iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pop-099665

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Eukaryotic translation initiation factor 3 subunit I

Genbank Nucleotide ID

CM000346

Gene Name

XM_002315798.1; POPTR_0010s11040g

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
POPTR_0010s11040	POPTR_0010s11040.1	POPTR_0010s11040.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.40e-19	67.9	50	87

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH++ v+c++   d  ll+++s D ++k+W++ tg +l
   Q: 50   GHNGAVWCCDVsRDsMLLITASADQSVKLWNVQTGAQL 87
           8***********77799***************999775 PP

Organism

Populus trichocarpa

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

MRPILMKGHE RPLTFLKYNR EGDLLFSCAK DHNPTVWFAD NGERLGTYRG HNGAVWCCDV 60
SRDSMLLITA SADQSVKLWN VQTGAQLFTF NFNSPARSVD FSVGDKLAVI TTDPFMGVTS 120

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Nucleotide Sequence
(Fasta)

ATGAGACCAA TCTTGATGAA AGGGCATGAA AGGCCCTTAA CATTCCTAAA ATACAACAGG 60
GAAGGAGATC TCTTGTTTTC TTGTGCTAAA GATCATAATC CCACCGTCTG GTTCGCCGAT 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-0675--Receptor
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027525--eIF3i
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0003743--F:translation initiation factor activity
GO:0001731--P:formation of translation preinitiation complex
GO:0006446--P:regulation of translational initiation

KEGG

pop:POPTR_0010s11040g

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-008000	Ashbya gossypii	45.97	2.00e-77	281.00
IUUC-Cel-018226	Caenorhabditis elegans	41.74	9.00e-71	259.00
IUUC-Kpa-049325	Komagataella pastoris	43.73	2.00e-77	281.00
IUUC-Rno-105867	Rattus norvegicus	44.51	7.00e-71	259.00
IUUC-Sre-115096	Sporisorium reilianum	44.67	3.00e-76	277.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence