iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xtr-132400

Ensembl Protein ID

ENSXETP00000048528.3

UniProt Accession

F6SP18; F6SP18_XENTR

Genbank Protein ID

ENSXETP00000048528

Protein Name

Hypermethylated in cancer 2

Genbank Nucleotide ID

AAMC01006274

Gene Name

hic2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000022419.3	ENSXETT00000048528.3	ENSXETP00000048528.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	7.80e-14	52.0	65	124

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.d.vqpevfrallkFlYtgkl 65
           +Dvi+vv++  f+ahk +LaasS +F++l l+        + ++++ d v p vfr++l+F+Ytgkl
   Q: 65   CDVIIVVENALFRAHKNILAASSMYFKSLVLH-------DNLINLDtDmVNPAVFRQILDFIYTGKL 124
           9*****************************99.......5789999889****************98 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

GVKSLAWPGS IRALCKCPPV PAAGWWCKAA CTWGTSKETV EMDLPNHAKQ MLLQLNQQRA 60
KGFLCDVIIV VENALFRAHK NILAASSMYF KSLVLHDNLI NLDTDMVNPA VFRQILDFIY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTGTCAAGA GTTTGGCATG GCCAGGTAGC ATAAGGGCAT AAAGCAGTGG TTCTCAACCT 60
TCCTAATGCC ACGATCCTTT AATACAGTTC CTCATGTTGT GGTGACCCCC AACCATAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0046872--F:metal ion binding
GO:0003676--F:nucleic acid binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004217	Anas platyrhynchos	73.03	0.00e+00	726.00
IUUC-Ame-010754	Astyanax mexicanus	62.72	6.00e-155	540.00
IUUC-Bta-013162	Bos taurus	56.77	2.00e-146	512.00
IUUC-Cfa-020537	Canis familiaris	65.71	1.00e-105	376.00
IUUC-Cpo-021843	Cavia porcellus	60.07	1.00e-172	599.00
IUUC-Csa-023171	Chlorocebus sabaeus	62.78	2.00e-101	362.00
IUUC-Dre-027672	Danio rerio	62.17	7.00e-178	616.00
IUUC-Dno-029125	Dasypus novemcinctus	83.94	2.00e-97	349.00
IUUC-Dor-030484	Dipodomys ordii	61.40	4.00e-63	234.00
IUUC-Ete-033019	Echinops telfairi	60.29	2.00e-55	210.00
IUUC-Eca-033737	Equus caballus	63.72	2.00e-101	363.00
IUUC-Eeu-035190	Erinaceus europaeus	46.79	1.00e-76	280.00
IUUC-Fca-036031	Felis catus	63.72	2.00e-102	366.00
IUUC-Fal-037342	Ficedula albicollis	71.80	0.00e+00	736.00
IUUC-Gmo-039209	Gadus morhua	59.93	1.00e-164	573.00
IUUC-Gga-040433	Gallus gallus	71.58	0.00e+00	727.00
IUUC-Gac-041588	Gasterosteus aculeatus	61.53	2.00e-173	602.00
IUUC-Ggo-045081	Gorilla gorilla	62.78	1.00e-101	363.00
IUUC-Hsa-046397	Homo sapiens	62.46	2.00e-101	363.00
IUUC-Itr-048738	Ictidomys tridecemlineatus	64.04	4.00e-102	365.00
IUUC-Lch-049980	Latimeria chalumnae	61.73	6.00e-163	566.00
IUUC-Loc-052129	Lepisosteus oculatus	71.58	0.00e+00	739.00
IUUC-Mcc-055370	Macaca mulatta	63.41	7.00e-103	367.00
IUUC-Mga-059911	Meleagris gallopavo	71.28	0.00e+00	713.00
IUUC-Mmr-060683	Microcebus murinus	60.88	2.00e-101	362.00
IUUC-Mdo-062271	Monodelphis domestica	60.54	2.00e-102	366.00
IUUC-Mmu-063688	Mus musculus	57.58	9.00e-165	573.00
IUUC-Mpu-066134	Mustela putorius furo	63.41	6.00e-102	364.00
IUUC-Mlu-067531	Myotis lucifugus	63.58	2.00e-104	372.00
IUUC-Nle-069726	Nomascus leucogenys	54.60	4.00e-84	305.00
IUUC-Opr-071056	Ochotona princeps	46.87	7.00e-86	311.00
IUUC-Ont-071390	Oreochromis niloticus	62.29	5.00e-177	613.00
IUUC-Ocu-073887	Oryctolagus cuniculus	58.86	5.00e-98	352.00
IUUC-Ola-087091	Oryzias latipes	58.27	2.00e-125	442.00
IUUC-Oga-088655	Otolemur garnettii	62.89	1.00e-103	370.00
IUUC-Ptr-090786	Pan troglodytes	62.78	2.00e-101	362.00
IUUC-Pan-092901	Papio anubis	62.78	3.00e-101	362.00
IUUC-Psi-093290	Pelodiscus sinensis	70.70	0.00e+00	747.00
IUUC-Pma-094179	Petromyzon marinus	70.51	6.00e-33	131.00
IUUC-Pfo-096241	Poecilia formosa	59.49	9.00e-155	540.00
IUUC-Pab-098162	Pongo abelii	62.78	3.00e-101	362.00
IUUC-Pca-101051	Procavia capensis	58.66	1.00e-158	553.00
IUUC-Rno-105690	Rattus norvegicus	57.40	7.00e-174	603.00
IUUC-Sre-115118	Sporisorium reilianum	32.61	2.00e-05	45.40
IUUC-Ssc-116215	Sus scrofa	64.10	3.00e-101	362.00
IUUC-Tgu-116768	Taeniopygia guttata	71.28	0.00e+00	728.00
IUUC-Tru-117833	Takifugu rubripes	58.28	2.00e-160	558.00
IUUC-Tni-119907	Tetraodon nigroviridis	53.97	2.00e-134	472.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence