iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-021214

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03007553

Gene Name

USP34

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000003007.4	ENSCAFT00000004838.4	ENSCAFP00000004484.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.40e-69	235.2	1881	2226

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           +Gl+Nlg+tCY+ S++Q+L++ipe r+++++ k++e++       ++++ l +lqk+f+ l++s+ ka++pr + k+  + ++ +++
   Q: 1881 VGLTNLGATCYLASTIQQLYMIPEARQAVFTaKYSEDM-------KHKTTLLELQKMFTYLMESECKAYNPRPFCKTYTMDKQPLNT 1960
           6******************************3444444.......4568899*********************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
            eq+D  Ef++ l+ ++ee                               + k++++ lF+g ++++++ l+c++vs++ e+f+++ 
   Q: 1961 GEQKDMTEFFTDLITKIEEMS----------------------------PELKNTVKSLFGGVITNNVVSLDCEHVSQTAEEFYTVR 2019
           *****************9977............................567899******************************** PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLd 260
           ++v + +     ++ ++L++ t +++leg+n+y c++c kk++aek+  +kklP++L+++ +R++f+  ++++ek+n++++fpl+Ld
   Q: 2020 CQVADMK-----NIYESLDEVTIKDTLEGDNMYTCSHCGKKVRAEKRACFKKLPRILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLD 2101
           *******.....9************************************************************************** PP
   S: 261  lspfcts................peekqkekkkYeLiavvvHsGslssGHYvayvkn.......ekgkWllfdDskVtevkeeevle 324
           ++p++++                + +k++e+++Y+Li+v vH+G++++GHY++++++       +++kW+lf+D +V++ + ++  +
   Q: 2102 MTPYTEDflmgksdrkegfkevsDHSKDTESYEYDLIGVTVHTGTADGGHYYSFIRDivnphayKNNKWYLFNDAEVKPFDSAQLAS 2188
           **********99999999999986666777***************************99999988999******************9 PP
   S: 325  etg........................staYvlfYkrr 338
           e+                         ++aY+lfYkr+
   Q: 2189 ECFggemttktydsvtdkfmdfsfektHSAYMLFYKRM 2226
           7779********************************96 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

SVSDIEGGDG LQLRKEHTLK IFAYINSWTQ RQCLCCFKEY KHLEIFNQVV CALINLVIAQ 60
VQVLRDQLCK HCATINIDST WQDETNQVEE PLNIERECNE GSTERQKSIE KKPNSTRICN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCAGTATCAG ATATAGAAGG TGGTGATGGA CTGCAGCTCA GAAAGGAACA TACTCTCAAA 60
ATATTTGCTT ATATCAATTC CTGGACACAG AGGTATGCAT CTTTAAGTAC TTTAAAGACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR011030--Vitellinogen_superhlx

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0071108--P:protein K48-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002257	Ailuropoda melanoleuca	99.38	0.00e+00	6895.00
IUUC-Apl-003284	Anas platyrhynchos	95.06	0.00e+00	6326.00
IUUC-Aca-004415	Anolis carolinensis	93.10	0.00e+00	6461.00
IUUC-Acl-008140	Aspergillus clavatus	28.97	8.00e-64	240.00
IUUC-Afl-008381	Aspergillus flavus	28.16	7.00e-64	240.00
IUUC-Afu-008857	Aspergillus fumigatus	27.35	5.00e-64	241.00
IUUC-Ani-009257	Aspergillus nidulans	28.87	1.00e-56	216.00
IUUC-Ang-009759	Aspergillus niger	28.02	7.00e-64	240.00
IUUC-Aor-009931	Aspergillus oryzae	27.09	5.00e-64	241.00
IUUC-Ate-010246	Aspergillus terreus	29.03	8.00e-53	203.00
IUUC-Ame-011219	Astyanax mexicanus	65.10	0.00e+00	2490.00
IUUC-Bgr-012195	Blumeria graminis	27.63	1.00e-64	243.00
IUUC-Bta-012989	Bos taurus	98.73	0.00e+00	6820.00
IUUC-Bci-013798	Botrytis cinerea	32.44	3.00e-58	221.00
IUUC-Cja-018974	Callithrix jacchus	97.17	0.00e+00	826.00
IUUC-Cpo-021912	Cavia porcellus	98.14	0.00e+00	4748.00
IUUC-Csa-023658	Chlorocebus sabaeus	98.50	0.00e+00	6818.00
IUUC-Cho-024971	Choloepus hoffmanni	84.11	0.00e+00	3218.00
IUUC-Cgl-026466	Colletotrichum gloeosporioides	27.99	4.00e-64	241.00
IUUC-Dre-027428	Danio rerio	85.28	0.00e+00	4641.00
IUUC-Dno-029690	Dasypus novemcinctus	98.01	0.00e+00	6686.00
IUUC-Dor-030817	Dipodomys ordii	88.94	0.00e+00	2156.00
IUUC-Dse-031423	Dothistroma septosporum	25.23	1.00e-35	147.00
IUUC-Dme-032102	Drosophila melanogaster	53.85	0.00e+00	849.00
IUUC-Ete-032552	Echinops telfairi	94.18	0.00e+00	3009.00
IUUC-Eca-033457	Equus caballus	99.06	0.00e+00	6578.00
IUUC-Eeu-035118	Erinaceus europaeus	94.51	0.00e+00	3085.00
IUUC-Fca-036213	Felis catus	96.96	0.00e+00	5101.00
IUUC-Fal-037643	Ficedula albicollis	92.59	0.00e+00	6423.00
IUUC-Fox-037971	Fusarium oxysporum	27.27	1.00e-63	239.00
IUUC-Fso-038108	Fusarium solani	27.10	2.00e-60	229.00
IUUC-Ggr-040075	Gaeumannomyces graminis	32.16	1.00e-62	236.00
IUUC-Gga-040511	Gallus gallus	92.42	0.00e+00	6459.00
IUUC-Gac-042024	Gasterosteus aculeatus	88.03	0.00e+00	5021.00
IUUC-Ggo-044924	Gorilla gorilla	94.60	0.00e+00	6280.00
IUUC-Hsa-046913	Homo sapiens	98.56	0.00e+00	6851.00
IUUC-Itr-048626	Ictidomys tridecemlineatus	98.59	0.00e+00	6858.00
IUUC-Lch-049675	Latimeria chalumnae	86.16	0.00e+00	4892.00
IUUC-Loc-052832	Lepisosteus oculatus	86.81	0.00e+00	5959.00
IUUC-Lma-053130	Leptosphaeria maculans	27.66	2.00e-61	232.00
IUUC-Laf-054169	Loxodonta africana	97.08	0.00e+00	6788.00
IUUC-Mcc-055847	Macaca mulatta	97.65	0.00e+00	6734.00
IUUC-Meu-056327	Macropus eugenii	85.38	0.00e+00	1566.00
IUUC-Mor-057152	Magnaporthe oryzae	35.14	9.00e-62	233.00
IUUC-Mpo-057310	Magnaporthe poae	26.28	3.00e-60	228.00
IUUC-Mmr-060780	Microcebus murinus	98.87	0.00e+00	6865.00
IUUC-Mdo-062308	Monodelphis domestica	93.06	0.00e+00	6201.00
IUUC-Mmu-063457	Mus musculus	96.39	0.00e+00	6742.00
IUUC-Mpu-066917	Mustela putorius furo	97.14	0.00e+00	6682.00
IUUC-Mlu-067696	Myotis lucifugus	98.70	0.00e+00	6828.00
IUUC-Nfi-068259	Neosartorya fischeri	27.70	2.00e-64	242.00
IUUC-Ncr-068911	Neurospora crassa	25.71	8.00e-60	227.00
IUUC-Nle-069586	Nomascus leucogenys	98.47	0.00e+00	6878.00
IUUC-Opr-070447	Ochotona princeps	94.19	0.00e+00	2895.00
IUUC-Ont-072396	Oreochromis niloticus	82.07	0.00e+00	5490.00
IUUC-Oan-073147	Ornithorhynchus anatinus	94.99	0.00e+00	6604.00
IUUC-Ocu-074324	Oryctolagus cuniculus	98.39	0.00e+00	6816.00
IUUC-Ola-086312	Oryzias latipes	82.27	0.00e+00	5300.00
IUUC-Oga-088878	Otolemur garnettii	98.81	0.00e+00	6867.00
IUUC-Oar-089919	Ovis aries	98.73	0.00e+00	6818.00
IUUC-Ptr-090713	Pan troglodytes	98.49	0.00e+00	6283.00
IUUC-Pan-091957	Papio anubis	99.00	0.00e+00	5140.00
IUUC-Psi-093240	Pelodiscus sinensis	93.95	0.00e+00	6534.00
IUUC-Pma-094469	Petromyzon marinus	73.05	0.00e+00	4092.00
IUUC-Pno-095059	Phaeosphaeria nodorum	29.39	4.00e-57	218.00
IUUC-Pfo-097159	Poecilia formosa	79.85	0.00e+00	5527.00
IUUC-Pab-098003	Pongo abelii	98.02	0.00e+00	6499.00
IUUC-Pca-100799	Procavia capensis	91.08	0.00e+00	1945.00
IUUC-Pva-103226	Pteropus vampyrus	93.83	0.00e+00	6418.00
IUUC-Pte-104235	Pyrenophora teres	32.13	1.00e-58	223.00
IUUC-Pyt-104803	Pyrenophora triticirepentis	27.36	4.00e-61	230.00
IUUC-Rno-105389	Rattus norvegicus	96.61	0.00e+00	5559.00
IUUC-Sha-106979	Sarcophilus harrisii	95.09	0.00e+00	6611.00
IUUC-Sar-113444	Sorex araneus	91.82	0.00e+00	6001.00
IUUC-Ssc-115815	Sus scrofa	98.19	0.00e+00	5678.00
IUUC-Tgu-117470	Taeniopygia guttata	94.38	0.00e+00	6253.00
IUUC-Tru-118543	Takifugu rubripes	82.45	0.00e+00	5381.00
IUUC-Tsy-119081	Tarsius syrichta	89.43	0.00e+00	4904.00
IUUC-Tni-120294	Tetraodon nigroviridis	83.21	3.00e-164	571.00
IUUC-Tre-122057	Trichoderma reesei	29.91	3.00e-63	238.00
IUUC-Tvi-122570	Trichoderma virens	35.89	2.00e-59	226.00
IUUC-Tme-127154	Tuber melanosporum	27.50	2.00e-59	224.00
IUUC-Tbe-127801	Tupaia belangeri	87.11	0.00e+00	3332.00
IUUC-Ttr-129262	Tursiops truncatus	94.54	0.00e+00	6489.00
IUUC-Vda-129686	Verticillium dahliae	27.91	4.00e-62	234.00
IUUC-Vpa-130484	Vicugna pacos	94.62	0.00e+00	6447.00
IUUC-Xtr-131769	Xenopus tropicalis	86.58	0.00e+00	6076.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence