iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000058664.2	ENSRNOT00000092901.1	ENSRNOP00000076011.1
ENSRNOG00000058664.2	ENSRNOT00000088719.1	ENSRNOP00000071193.1

Annotation

Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	8.00e-82	275.5	1555	1954

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.............kkkeklneenp...............................k 43
           +GlkN g+tCYmNSv+Q+L++ip++r+ +l              k      +e +                               k
   Q: 1555 VGLKNAGATCYMNSVIQQLYMIPSIRNSILAieniwndtdddtfK------DERQdsennidprddvfgyphqfedkptlnkaedrK 1635
           6******************************88888775544331......222244446677777888877777777777777777 PP
   S: 44   epkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdea 130
           + +  +lk+lq  f +l  s+ +++ pr ++++++ + e ++  eq+Da Ef++ l+d+l+e++                       
   Q: 1636 DYNIGVLKHLQITFGHLAASQLQYYVPRGFWQQFRLWGEPVNLREQHDALEFFNSLVDSLDEAF----------------------- 1699
           7777************************************************************....................... PP
   S: 131  eekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqea 217
              k   +++l+s++++g++ +q +c+ c ++++ ee+f++l++++++++     +l d+Le++ k + leg+n+y+cekc+kk+++
   Q: 1700 ---KALGHPTLLSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQ-----NLLDSLEQYIKGDLLEGANAYHCEKCDKKVDT 1778
           ...77999******************************************.....9******************************* PP
   S: 218  ekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts.................peekqke..........kkk 277
           +k+l +kklP vL ++LkRf ++ e+++ +k+n+++efp+eLd++p+++                  +     +          ++k
   Q: 1779 VKRLLIKKLPSVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAgatklegdgvhpqtqliK-----QneqsenvvpgSTK 1860
           **************************************************666666666666665552.....04455578888*** PP
   S: 278  YeLiavvvHsGslssGHYvayvknekgk......WllfdDskVtevkeeevleetg...........................staY 331
           Y+L++v+vHsG++++GHY++y+ +++gk      W++fdD  Vte+k+++ +e+++                           ++aY
   Q: 1861 YRLVGVLVHSGQANGGHYYSYIIQRNGKdnnrgrWFKFDDGDVTECKMDDDEEMKNqcfggeymgevfdhmmkrmsyrrqkrwWNAY 1947
           ************************5555555667*******************9999****************************** PP
   S: 332  vlfYkrr 338
           +lfY+r+
   Q: 1948 ILFYERM 1954
           *****96 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MTVTTRGSPV GENESQGQAP DGQSQPSFQQ NQISSSDSSN ENSPATPPDE QGQGDAPPQH 60
EEEDPTFPHA DLAKLEDMIN RPRWVVPVLP KGELEVLLEA SIDLTKKGID AKSEACQRFF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTGGTGCTA AGGGCTAAGG GGCGTGGCTT TGCAGGCGTT GAGATCCCTT GAGCCTTTGC 60
GTGGCGCTAA GGCTGTTGGG AGTTTTCATT TCTCAGCGTC GAGCGGTTGG GTCCGCCATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005737--C:cytoplasm
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016477--P:cell migration
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID

Species

Identity

E-value

Score

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence