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Tag Content
UUCD2 ID IUUC-Bta-013522
UUCD1 version UUC-BoT-00873
Ensembl Protein ID ENSBTAP00000021554.4
UniProt Accession Q2KHT6; FBX32_BOVIN
Genbank Protein ID AAI12889.1
Protein Name F-box only protein 32
Genbank Nucleotide ID BC112888
Gene Name FBXO32
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSBTAG00000016194.4 ENSBTAT00000021554.4 ENSBTAP00000021554.4
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 adaptor/Cullin RING/SCF/F-box 27.62 3.00e-35 145.00 IUUC-Cel-018348
E3 adaptor/Cullin RING/SCF/F-box 98.03 0.00e+00 727.00 IUUC-Hsa-046173
E3 adaptor/Cullin RING/SCF/F-box 94.37 0.00e+00 697.00 IUUC-Rno-105610
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Bos taurus
Functional Description
(View)

Functional Description


     Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1 (By similarity).
 Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1 (By similarity).
Protein Sequence
(Fasta)
MPFLGQDWRS PGQSWVKTAD GWKRFLDEKS GSFVSDLGSY CSKEVYNKEN LFNSLNYDVA 60
AKKRKKDMLN SKTKTQYFHQ EKWIYVHKGS TKERHGYCTL GEAFNRLDFS TAILDSRRFN 120
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Protein Fasta Sequence


>IUUC-Bta-013522|E3,F-box|Bos taurus
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Nucleotide Sequence
(Fasta)
ATGCCATTCC TCGGGCAGGA CTGGCGGTCG CCGGGGCAGA GCTGGGTGAA GACAGCGGAT 60
GGCTGGAAAC GCTTCCTGGA CGAGAAGAGC GGCAGCTTCG TGAGCGACCT CGGCAGGTGA 120
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Nucleotide Fasta Sequence


>IUUC-Bta-013522|E3,F-box|Bos taurus
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Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
Interpro

IPR001810--F-box_dom
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0030018--C:Z disc
GO:0071549--P:cellular response to dexamethasone stimulus
GO:0016567--P:protein ubiquitination
GO:0014894--P:response to denervation involved in regulation of muscle adaptation
KEGG bta:513776
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001986 Ailuropoda melanoleuca 98.59 0.00e+00 731.00
IUUC-Apl-003973 Anas platyrhynchos 92.79 7.00e-179 619.00
IUUC-Aca-004945 Anolis carolinensis 89.30 0.00e+00 655.00
IUUC-Ame-011383 Astyanax mexicanus 75.49 3.00e-164 570.00
IUUC-Bdi-014435 Brachypodium distachyon 37.50 6.00e-05 41.20
IUUC-Bol-015763 Brassica oleracea 28.81 3.80e-02 31.60
IUUC-Cel-018348 Caenorhabditis elegans 27.62 4.00e-36 145.00
IUUC-Cja-019893 Callithrix jacchus 98.03 0.00e+00 727.00
IUUC-Cfa-021053 Canis familiaris 98.59 0.00e+00 730.00
IUUC-Cpo-021330 Cavia porcellus 97.46 0.00e+00 723.00
IUUC-Csa-023160 Chlorocebus sabaeus 98.31 0.00e+00 728.00
IUUC-Cho-024993 Choloepus hoffmanni 77.23 5.00e-131 460.00
IUUC-Cin-025462 Ciona intestinalis 29.79 1.00e-25 109.00
IUUC-Csv-025908 Ciona savignyi 30.65 7.00e-43 167.00
IUUC-Cme-027326 Cyanidioschyzon merolae 24.00 1.70e-02 32.00
IUUC-Dre-028707 Danio rerio 76.19 1.00e-161 562.00
IUUC-Dno-029334 Dasypus novemcinctus 97.18 0.00e+00 723.00
IUUC-Dor-030350 Dipodomys ordii 97.07 0.00e+00 679.00
IUUC-Dme-031699 Drosophila melanogaster 27.62 8.00e-32 130.00
IUUC-Ete-033123 Echinops telfairi 76.97 2.00e-133 468.00
IUUC-Eca-033246 Equus caballus 98.59 0.00e+00 727.00
IUUC-Eeu-035339 Erinaceus europaeus 98.27 2.00e-133 468.00
IUUC-Fca-035805 Felis catus 98.58 0.00e+00 720.00
IUUC-Fal-037424 Ficedula albicollis 92.11 0.00e+00 691.00
IUUC-Gmo-039533 Gadus morhua 52.73 7.00e-105 373.00
IUUC-Gga-040478 Gallus gallus 93.24 0.00e+00 694.00
IUUC-Gac-042238 Gasterosteus aculeatus 73.13 1.00e-157 548.00
IUUC-Ggo-045515 Gorilla gorilla 98.31 0.00e+00 728.00
IUUC-Hsa-046173 Homo sapiens 98.03 0.00e+00 727.00
IUUC-Itr-048038 Ictidomys tridecemlineatus 98.03 0.00e+00 726.00
IUUC-Lch-049820 Latimeria chalumnae 81.69 8.00e-176 609.00
IUUC-Loc-051732 Lepisosteus oculatus 79.44 7.00e-171 592.00
IUUC-Laf-053789 Loxodonta africana 96.36 0.00e+00 684.00
IUUC-Mcc-055119 Macaca mulatta 98.31 0.00e+00 728.00
IUUC-Meu-056262 Macropus eugenii 79.72 4.00e-96 344.00
IUUC-Mga-059869 Meleagris gallopavo 85.96 2.00e-176 611.00
IUUC-Mmr-061443 Microcebus murinus 98.03 0.00e+00 726.00
IUUC-Mdo-062355 Monodelphis domestica 95.21 0.00e+00 711.00
IUUC-Mmu-064306 Mus musculus 95.21 0.00e+00 710.00
IUUC-Mpu-066902 Mustela putorius furo 98.47 0.00e+00 637.00
IUUC-Mlu-067076 Myotis lucifugus 97.18 0.00e+00 720.00
IUUC-Nle-069716 Nomascus leucogenys 98.31 0.00e+00 728.00
IUUC-Opr-070514 Ochotona princeps 68.29 7.00e-27 113.00
IUUC-Ont-072007 Oreochromis niloticus 74.30 9.00e-157 546.00
IUUC-Oan-073321 Ornithorhynchus anatinus 95.32 1.00e-160 558.00
IUUC-Ocu-074320 Oryctolagus cuniculus 96.62 0.00e+00 694.00
IUUC-Ola-087193 Oryzias latipes 73.74 6.00e-160 556.00
IUUC-Oga-088558 Otolemur garnettii 97.75 0.00e+00 726.00
IUUC-Oar-090092 Ovis aries 99.15 0.00e+00 731.00
IUUC-Ptr-091443 Pan troglodytes 97.18 0.00e+00 720.00
IUUC-Pan-092207 Papio anubis 98.31 0.00e+00 728.00
IUUC-Psi-093282 Pelodiscus sinensis 91.06 0.00e+00 682.00
IUUC-Pma-094448 Petromyzon marinus 67.60 9.00e-145 506.00
IUUC-Pfo-096873 Poecilia formosa 74.02 2.00e-161 561.00
IUUC-Pab-097940 Pongo abelii 61.94 3.00e-125 441.00
IUUC-Pca-101124 Procavia capensis 95.49 0.00e+00 705.00
IUUC-Pva-102791 Pteropus vampyrus 97.18 0.00e+00 722.00
IUUC-Rno-105610 Rattus norvegicus 94.37 0.00e+00 697.00
IUUC-Sha-106684 Sarcophilus harrisii 95.21 0.00e+00 712.00
IUUC-Smo-109491 Selaginella moellendorffii 22.91 4.00e-04 39.30
IUUC-Sar-113077 Sorex araneus 87.03 1.00e-163 568.00
IUUC-Ssc-115993 Sus scrofa 95.49 0.00e+00 700.00
IUUC-Tgu-117376 Taeniopygia guttata 91.85 7.00e-178 615.00
IUUC-Tru-118690 Takifugu rubripes 73.74 5.00e-160 556.00
IUUC-Tsy-119123 Tarsius syrichta 61.25 2.00e-75 275.00
IUUC-Tni-120740 Tetraodon nigroviridis 72.35 2.00e-159 555.00
IUUC-Tbe-127713 Tupaia belangeri 88.29 1.00e-163 568.00
IUUC-Ttr-128339 Tursiops truncatus 98.87 0.00e+00 731.00
IUUC-Vpa-130070 Vicugna pacos 99.28 2.00e-81 295.00
IUUC-Xtr-132470 Xenopus tropicalis 83.94 0.00e+00 629.00
Created Date 25-Jun-2017

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