iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066326

Ensembl Protein ID

ENSMPUP00000007189.1

UniProt Accession

M3Y782; M3Y782_MUSPF

Genbank Protein ID

ENSMPUP00000007189

Protein Name

Non-specific serine/threonine protein kinase

Genbank Nucleotide ID

AEYP01029363

Gene Name

PRKAA2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000007247.1	ENSMPUT00000007308.1	ENSMPUP00000007189.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	47.57	8.00e-117	417.00	IUUC-Ath-007014
UBD/Alpha-Helix/UBA	40.65	2.00e-99	357.00	IUUC-Spo-108202

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MNLVGEHQLT GHKVAVKILN RQKIRSLDVV GKIKREIQNL KLFRHPHIIK LYQVISTPTD 60
FFMVMEYVSG GELFDYICKH GRVEEVEARR LFQQILSAVD YCHRHMVVHR DLKPENVLLD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGGAGAGAG AGAGCGAAAG AGAGAGAGAA CGAGCCGGGA ACAGTAGCAG AGGGAGAAGG 60
AGAAGCAGGC TCCCCACTGA TCAAGGAATC AGATACCAGG ACTTGATCCC AGGACCCAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR032270--AMPK_C
IPR028375--KA1/Ssp2_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF16579--AdenylateSensor
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005794--C:Golgi apparatus
GO:0016607--C:nuclear speck
GO:0004679--F:AMP-activated protein kinase activity
GO:0005524--F:ATP binding
GO:0003682--F:chromatin binding
GO:0035174--F:histone serine kinase activity
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0035690--P:cellular response to drug
GO:0042149--P:cellular response to glucose starvation
GO:0071380--P:cellular response to prostaglandin E stimulus
GO:0042593--P:glucose homeostasis
GO:0008610--P:lipid biosynthetic process
GO:0043066--P:negative regulation of apoptotic process
GO:0032007--P:negative regulation of TOR signaling
GO:0010508--P:positive regulation of autophagy
GO:0042752--P:regulation of circadian rhythm
GO:0010468--P:regulation of gene expression
GO:0016241--P:regulation of macroautophagy
GO:0014850--P:response to muscle activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000713	Aegilops tauschii	46.92	7.00e-116	411.00
IUUC-Aml-001907	Ailuropoda melanoleuca	73.85	0.00e+00	756.00
IUUC-Atr-002770	Amborella trichopoda	46.75	7.00e-117	414.00
IUUC-Apl-003395	Anas platyrhynchos	94.06	0.00e+00	1026.00
IUUC-Aca-004480	Anolis carolinensis	94.09	0.00e+00	970.00
IUUC-Aly-006289	Arabidopsis lyrata	47.46	4.00e-118	418.00
IUUC-Ath-007014	Arabidopsis thaliana	47.57	2.00e-118	419.00
IUUC-Ago-007957	Ashbya gossypii	42.14	1.00e-108	387.00
IUUC-Acl-008103	Aspergillus clavatus	61.96	6.00e-96	345.00
IUUC-Afl-008555	Aspergillus flavus	61.57	2.00e-96	346.00
IUUC-Afu-008949	Aspergillus fumigatus	61.96	4.00e-96	345.00
IUUC-Ani-009408	Aspergillus nidulans	64.34	1.00e-96	347.00
IUUC-Ang-009551	Aspergillus niger	61.96	6.00e-96	345.00
IUUC-Aor-010176	Aspergillus oryzae	61.57	2.00e-96	347.00
IUUC-Ate-010287	Aspergillus terreus	61.96	5.00e-96	345.00
IUUC-Ame-011019	Astyanax mexicanus	85.66	0.00e+00	947.00
IUUC-Bgr-012045	Blumeria graminis	61.94	4.00e-95	342.00
IUUC-Bta-012786	Bos taurus	74.71	0.00e+00	758.00
IUUC-Bci-013774	Botrytis cinerea	46.48	2.00e-97	350.00
IUUC-Bdi-014319	Brachypodium distachyon	47.57	2.00e-116	412.00
IUUC-Bol-016242	Brassica oleracea	47.65	3.00e-121	428.00
IUUC-Bra-016750	Brassica rapa	47.65	1.00e-121	429.00
IUUC-Cel-018518	Caenorhabditis elegans	58.33	1.00e-169	589.00
IUUC-Cja-019386	Callithrix jacchus	98.85	0.00e+00	1040.00
IUUC-Cfa-020177	Canis familiaris	73.80	0.00e+00	762.00
IUUC-Cpo-021805	Cavia porcellus	98.27	0.00e+00	1036.00
IUUC-Cre-022915	Chlamydomonas reinhardtii	54.64	8.00e-89	320.00
IUUC-Csa-024267	Chlorocebus sabaeus	98.85	0.00e+00	1025.00
IUUC-Cho-024859	Choloepus hoffmanni	71.69	0.00e+00	749.00
IUUC-Cin-025550	Ciona intestinalis	60.80	0.00e+00	633.00
IUUC-Csv-026139	Ciona savignyi	58.98	0.00e+00	632.00
IUUC-Cne-027044	Cryptococcus neoformans	50.27	3.00e-100	359.00
IUUC-Cme-027289	Cyanidioschyzon merolae	43.97	3.00e-101	362.00
IUUC-Dre-027749	Danio rerio	69.84	0.00e+00	737.00
IUUC-Dno-030006	Dasypus novemcinctus	73.65	0.00e+00	754.00
IUUC-Dor-030578	Dipodomys ordii	97.70	0.00e+00	1032.00
IUUC-Dse-031507	Dothistroma septosporum	64.34	1.00e-97	350.00
IUUC-Dme-031704	Drosophila melanogaster	59.05	0.00e+00	644.00
IUUC-Ete-033055	Echinops telfairi	72.39	0.00e+00	780.00
IUUC-Eca-034016	Equus caballus	98.66	0.00e+00	1036.00
IUUC-Fca-035754	Felis catus	71.91	0.00e+00	749.00
IUUC-Fal-037363	Ficedula albicollis	74.42	0.00e+00	755.00
IUUC-Fox-038073	Fusarium oxysporum	52.51	7.00e-99	354.00
IUUC-Fso-038236	Fusarium solani	52.11	2.00e-95	343.00
IUUC-Gmo-039633	Gadus morhua	69.61	0.00e+00	763.00
IUUC-Ggr-039987	Gaeumannomyces graminis	48.83	2.00e-95	343.00
IUUC-Gga-040546	Gallus gallus	92.32	0.00e+00	1001.00
IUUC-Gac-041822	Gasterosteus aculeatus	83.43	0.00e+00	890.00
IUUC-Gma-042712	Glycine max	46.03	6.00e-117	414.00
IUUC-Ggo-045303	Gorilla gorilla	99.04	0.00e+00	1043.00
IUUC-Hsa-045746	Homo sapiens	99.04	0.00e+00	1043.00
IUUC-Hvu-047406	Hordeum vulgare	47.02	3.00e-117	415.00
IUUC-Itr-048134	Ictidomys tridecemlineatus	98.46	0.00e+00	1038.00
IUUC-Kpa-049190	Komagataella pastoris	44.92	8.00e-114	404.00
IUUC-Lch-049623	Latimeria chalumnae	72.32	0.00e+00	750.00
IUUC-Lpe-051392	Leersia perrieri	46.07	1.00e-116	413.00
IUUC-Loc-052928	Lepisosteus oculatus	90.04	0.00e+00	971.00
IUUC-Lma-053054	Leptosphaeria maculans	63.56	2.00e-98	353.00
IUUC-Laf-053459	Loxodonta africana	97.70	0.00e+00	1033.00
IUUC-Mcc-055862	Macaca mulatta	99.04	0.00e+00	1043.00
IUUC-Mor-057170	Magnaporthe oryzae	50.62	1.00e-93	337.00
IUUC-Mpo-057302	Magnaporthe poae	49.27	7.00e-96	344.00
IUUC-Mtr-058309	Medicago truncatula	47.30	3.00e-116	411.00
IUUC-Mla-059058	Melampsora laricipopulina	41.57	9.00e-98	350.00
IUUC-Mga-059206	Meleagris gallopavo	92.13	0.00e+00	1000.00
IUUC-Mvi-060337	Microbotryum violaceum	41.40	7.00e-102	364.00
IUUC-Mmr-061619	Microcebus murinus	97.70	0.00e+00	1023.00
IUUC-Mdo-062160	Monodelphis domestica	93.28	0.00e+00	1009.00
IUUC-Mmu-063406	Mus musculus	97.31	0.00e+00	1020.00
IUUC-Mac-064518	Musa acuminata	44.65	2.00e-113	402.00
IUUC-Mlu-067968	Myotis lucifugus	97.71	0.00e+00	1002.00
IUUC-Nfi-068493	Neosartorya fischeri	61.96	3.00e-96	346.00
IUUC-Ncr-068665	Neurospora crassa	42.09	6.00e-101	361.00
IUUC-Nle-070158	Nomascus leucogenys	98.85	0.00e+00	1040.00
IUUC-Opr-070272	Ochotona princeps	71.72	0.00e+00	748.00
IUUC-Ont-071395	Oreochromis niloticus	86.10	0.00e+00	934.00
IUUC-Oan-073322	Ornithorhynchus anatinus	71.67	0.00e+00	742.00
IUUC-Ocu-074188	Oryctolagus cuniculus	72.52	0.00e+00	749.00
IUUC-Oba-075436	Oryza barthii	46.60	2.00e-118	419.00
IUUC-Obr-076507	Oryza brachyantha	46.92	3.00e-117	415.00
IUUC-Ogl-077718	Oryza glaberrima	49.53	7.00e-116	410.00
IUUC-Ogu-078349	Oryza glumaepatula	46.60	2.00e-118	419.00
IUUC-Oin-079889	Oryza indica	45.44	2.00e-116	412.00
IUUC-Olo-080521	Oryza longistaminata	46.60	2.00e-118	419.00
IUUC-Ome-081630	Oryza meridionalis	46.38	5.00e-118	417.00
IUUC-Oni-082211	Oryza nivara	46.60	2.00e-118	419.00
IUUC-Opu-083617	Oryza punctata	46.28	4.00e-117	414.00
IUUC-Oru-084252	Oryza rufipogon	46.60	3.00e-118	418.00
IUUC-Osa-085548	Oryza sativa	46.60	3.00e-118	418.00
IUUC-Ola-087169	Oryzias latipes	84.00	0.00e+00	909.00
IUUC-Olu-087861	Ostreococcus lucimarinus	48.05	5.00e-109	388.00
IUUC-Oga-088003	Otolemur garnettii	73.85	0.00e+00	757.00
IUUC-Oar-089933	Ovis aries	74.71	0.00e+00	758.00
IUUC-Ptr-090741	Pan troglodytes	99.04	0.00e+00	1043.00
IUUC-Pan-092526	Papio anubis	74.04	0.00e+00	758.00
IUUC-Psi-094034	Pelodiscus sinensis	73.85	0.00e+00	754.00
IUUC-Pno-095030	Phaeosphaeria nodorum	63.56	8.00e-97	347.00
IUUC-Ppa-095615	Physcomitrella patens	44.82	3.00e-116	412.00
IUUC-Pfo-096295	Poecilia formosa	85.14	0.00e+00	920.00
IUUC-Pab-098023	Pongo abelii	99.04	0.00e+00	1043.00
IUUC-Pop-100042	Populus trichocarpa	47.16	6.00e-120	424.00
IUUC-Pca-101104	Procavia capensis	78.34	2.00e-164	572.00
IUUC-Ppe-101642	Prunus persica	48.03	2.00e-117	416.00
IUUC-Pva-102470	Pteropus vampyrus	97.70	0.00e+00	1024.00
IUUC-Pgr-103406	Puccinia graminis	61.63	4.00e-85	309.00
IUUC-Ptt-103713	Puccinia triticina	38.96	5.00e-76	278.00
IUUC-Pte-104259	Pyrenophora teres	63.16	8.00e-98	351.00
IUUC-Pyt-104752	Pyrenophora triticirepentis	63.56	1.00e-98	353.00
IUUC-Rno-104960	Rattus norvegicus	97.89	0.00e+00	1032.00
IUUC-Sce-106290	Saccharomyces cerevisiae	42.15	3.00e-109	389.00
IUUC-Sha-107603	Sarcophilus harrisii	73.65	0.00e+00	754.00
IUUC-Sja-107772	Schizosaccharomyces japonicus	39.92	7.00e-104	370.00
IUUC-Spo-108202	Schizosaccharomyces pombe	40.65	1.00e-99	357.00
IUUC-Ssl-108535	Sclerotinia sclerotiorum	48.53	1.00e-96	347.00
IUUC-Smo-109309	Selaginella moellendorffii	44.97	3.00e-114	405.00
IUUC-Sit-109745	Setaria italica	47.49	2.00e-119	422.00
IUUC-Sly-110890	Solanum lycopersicum	46.86	1.00e-118	420.00
IUUC-Stu-112144	Solanum tuberosum	45.36	4.00e-112	398.00
IUUC-Sar-113521	Sorex araneus	65.33	0.00e+00	636.00
IUUC-Sbi-114764	Sorghum bicolor	47.10	3.00e-120	425.00
IUUC-Sre-115141	Sporisorium reilianum	67.74	8.00e-106	378.00
IUUC-Ssc-115732	Sus scrofa	73.80	0.00e+00	760.00
IUUC-Tgu-117190	Taeniopygia guttata	74.62	0.00e+00	754.00
IUUC-Tru-118735	Takifugu rubripes	84.38	0.00e+00	920.00
IUUC-Tsy-119503	Tarsius syrichta	95.58	0.00e+00	984.00
IUUC-Tni-119880	Tetraodon nigroviridis	85.31	0.00e+00	926.00
IUUC-Tca-121386	Theobroma cacao	46.43	3.00e-119	421.00
IUUC-Tre-122070	Trichoderma reesei	48.91	1.00e-96	347.00
IUUC-Tvi-122305	Trichoderma virens	50.59	4.00e-95	342.00
IUUC-Tae-123515	Triticum aestivum	47.12	9.00e-119	420.00
IUUC-Tur-126416	Triticum urartu	46.92	8.00e-116	410.00
IUUC-Tme-127174	Tuber melanosporum	40.30	1.00e-66	247.00
IUUC-Tbe-127791	Tupaia belangeri	86.09	3.00e-113	401.00
IUUC-Ttr-129224	Tursiops truncatus	71.91	0.00e+00	747.00
IUUC-Uma-129372	Ustilago maydis	67.74	4.00e-105	375.00
IUUC-Vda-129819	Verticillium dahliae	53.82	1.00e-79	290.00
IUUC-Vpa-130220	Vicugna pacos	98.27	0.00e+00	1030.00
IUUC-Vvi-131649	Vitis vinifera	47.15	9.00e-118	417.00
IUUC-Xtr-132954	Xenopus tropicalis	92.51	0.00e+00	1006.00
IUUC-Xma-134119	Xiphophorus maculatus	84.95	0.00e+00	918.00
IUUC-Yli-134422	Yarrowia lipolytica	45.27	2.00e-112	399.00
IUUC-Zma-135621	Zea mays	61.92	5.00e-112	398.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence