iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-098519

Ensembl Protein ID

ENSPPYP00000017227.2

UniProt Accession

H2PFE9; H2PFE9_PONAB

Genbank Protein ID

ENSPPYP00000017227

Protein Name

Non-specific serine/threonine protein kinase

Genbank Nucleotide ID

ABGA01152405

Gene Name

PRKAA1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000015421.2	ENSPPYT00000017927.2	ENSPPYP00000017227.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	40.28	3.00e-98	353.00	IUUC-Spo-108202

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pongo abelii

Protein Sequence
(Fasta)

MRRLSSWRKM ATAEKQKHDG RVKIGHYILG DTLGVGTFGK VKVGKHELTG HKVAVKILNR 60
QKIRSLDVVG KIRREIQNLK LFRHPHIIKL YQVISTPSDI FMVMEYVSGG ELFDYICKNG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCCCTCCG CCCCCTCCCG CAGCGCCATG CGCAGACTCA GTTCCTGGAG AAAGATGGCG 60
ACAGCCGAGA AGCAGAAACA CGACGGGCGG GTGAAGATCG GCCACTACAT CCTGGGTGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR032270--AMPK_C
IPR028375--KA1/Ssp2_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF16579--AdenylateSensor
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005829--C:cytosol
GO:0016607--C:nuclear speck
GO:0004679--F:AMP-activated protein kinase activity
GO:0005524--F:ATP binding
GO:0003682--F:chromatin binding
GO:0035174--F:histone serine kinase activity
GO:0061762--P:CAMKK-AMPK signaling cascade
GO:0042149--P:cellular response to glucose starvation
GO:0071380--P:cellular response to prostaglandin E stimulus
GO:0019395--P:fatty acid oxidation
GO:0042593--P:glucose homeostasis
GO:0006006--P:glucose metabolic process
GO:0008610--P:lipid biosynthetic process
GO:0043066--P:negative regulation of apoptotic process
GO:0050995--P:negative regulation of lipid catabolic process
GO:0032007--P:negative regulation of TOR signaling
GO:0010508--P:positive regulation of autophagy
GO:0010628--P:positive regulation of gene expression
GO:0048643--P:positive regulation of skeletal muscle tissue development
GO:0042752--P:regulation of circadian rhythm
GO:0033135--P:regulation of peptidyl-serine phosphorylation
GO:1901563--P:response to camptothecin
GO:0010332--P:response to gamma radiation
GO:0042542--P:response to hydrogen peroxide
GO:0009411--P:response to UV

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001907	Ailuropoda melanoleuca	99.28	0.00e+00	1056.00
IUUC-Atr-002770	Amborella trichopoda	48.47	4.00e-125	441.00
IUUC-Bta-012786	Bos taurus	99.28	0.00e+00	1066.00
IUUC-Cfa-020177	Canis familiaris	99.42	0.00e+00	1003.00
IUUC-Cho-024859	Choloepus hoffmanni	96.99	0.00e+00	989.00
IUUC-Cme-027289	Cyanidioschyzon merolae	46.44	2.00e-111	395.00
IUUC-Dre-027749	Danio rerio	83.28	0.00e+00	947.00
IUUC-Dno-030006	Dasypus novemcinctus	98.93	0.00e+00	1048.00
IUUC-Ete-033055	Echinops telfairi	95.94	0.00e+00	1058.00
IUUC-Eca-034239	Equus caballus	99.81	0.00e+00	1003.00
IUUC-Fca-035754	Felis catus	96.32	0.00e+00	1034.00
IUUC-Fal-037363	Ficedula albicollis	93.59	0.00e+00	1006.00
IUUC-Gmo-039633	Gadus morhua	82.43	0.00e+00	974.00
IUUC-Ggo-044797	Gorilla gorilla	99.82	0.00e+00	1058.00
IUUC-Hsa-045867	Homo sapiens	100.00	0.00e+00	1058.00
IUUC-Lch-049623	Latimeria chalumnae	90.02	0.00e+00	952.00
IUUC-Lpe-051392	Leersia perrieri	52.24	2.00e-125	442.00
IUUC-Loc-052362	Lepisosteus oculatus	90.00	0.00e+00	932.00
IUUC-Laf-053799	Loxodonta africana	99.28	0.00e+00	1089.00
IUUC-Mor-057170	Magnaporthe oryzae	49.87	5.00e-102	365.00
IUUC-Mtr-058309	Medicago truncatula	48.64	2.00e-125	442.00
IUUC-Mmr-061761	Microcebus murinus	99.64	0.00e+00	1055.00
IUUC-Mlu-068227	Myotis lucifugus	98.45	0.00e+00	996.00
IUUC-Opr-070272	Ochotona princeps	95.64	0.00e+00	1032.00
IUUC-Ont-072027	Oreochromis niloticus	83.68	0.00e+00	948.00
IUUC-Oan-073322	Ornithorhynchus anatinus	88.17	0.00e+00	983.00
IUUC-Ocu-074188	Oryctolagus cuniculus	96.63	0.00e+00	1021.00
IUUC-Oba-075436	Oryza barthii	48.24	2.00e-126	446.00
IUUC-Obr-076507	Oryza brachyantha	48.16	8.00e-127	447.00
IUUC-Ogu-078349	Oryza glumaepatula	47.59	2.00e-126	446.00
IUUC-Ome-081630	Oryza meridionalis	48.03	4.00e-126	444.00
IUUC-Oni-082211	Oryza nivara	48.24	7.00e-127	447.00
IUUC-Opu-083617	Oryza punctata	47.47	1.00e-125	443.00
IUUC-Oru-084252	Oryza rufipogon	48.24	1.00e-126	446.00
IUUC-Osa-085548	Oryza sativa	48.24	1.00e-126	446.00
IUUC-Ola-086366	Oryzias latipes	83.88	0.00e+00	960.00
IUUC-Olu-087861	Ostreococcus lucimarinus	48.75	4.00e-118	418.00
IUUC-Oga-088003	Otolemur garnettii	99.82	0.00e+00	1057.00
IUUC-Oar-089933	Ovis aries	99.28	0.00e+00	1066.00
IUUC-Ptr-090718	Pan troglodytes	100.00	0.00e+00	1058.00
IUUC-Pan-092526	Papio anubis	99.82	0.00e+00	1057.00
IUUC-Psi-094034	Pelodiscus sinensis	93.40	0.00e+00	1006.00
IUUC-Pfo-097050	Poecilia formosa	83.80	0.00e+00	951.00
IUUC-Pop-099781	Populus trichocarpa	54.01	8.00e-127	447.00
IUUC-Pca-101104	Procavia capensis	95.43	0.00e+00	764.00
IUUC-Sha-107603	Sarcophilus harrisii	97.32	0.00e+00	1042.00
IUUC-Spo-108202	Schizosaccharomyces pombe	40.67	2.00e-107	382.00
IUUC-Smo-109309	Selaginella moellendorffii	46.26	1.00e-122	433.00
IUUC-Sit-109745	Setaria italica	53.16	2.00e-127	449.00
IUUC-Sar-113521	Sorex araneus	89.73	0.00e+00	866.00
IUUC-Sbi-114764	Sorghum bicolor	48.36	2.00e-128	452.00
IUUC-Ssc-115732	Sus scrofa	99.42	0.00e+00	1000.00
IUUC-Tgu-117190	Taeniopygia guttata	93.06	0.00e+00	999.00
IUUC-Tni-119833	Tetraodon nigroviridis	83.88	0.00e+00	944.00
IUUC-Tre-122070	Trichoderma reesei	49.21	1.00e-103	370.00
IUUC-Tme-127174	Tuber melanosporum	39.38	2.00e-68	253.00
IUUC-Ttr-129224	Tursiops truncatus	95.47	0.00e+00	1052.00
IUUC-Vvi-131649	Vitis vinifera	48.57	8.00e-126	443.00
IUUC-Xma-134082	Xiphophorus maculatus	84.03	0.00e+00	874.00
IUUC-Zma-135621	Zea mays	53.49	9.00e-122	431.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence