iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045120

UUCD1 version

UUC-GoG-00214

Ensembl Protein ID

ENSGGOP00000005107.2

UniProt Accession

G3QR69; G3QR69_GORGO

Protein Name

Uncharacterized protein

Gene Name

WDR77

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000005208.2	ENSGGOT00000005238.2	ENSGGOP00000005107.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.10e-17	62.4	127	163

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H d v+ ++  s+ t  vsGs D  ikvWDl ++v+l
   Q: 127  HDDIVSTVSVlSSgTQAVSGSKDICIKVWDLAQQVVL 163
           89999999977555*****************999987 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

AVEMRKETPP PLVPPAAREW NLPPNAPACM ERQLEAARYR SDGALLLGAS SLSGRCWAGS 60
LWLFKDPCAA PNEGFCSAGV QTEAGVADLT WVGERGILVA SDSGAVELWE LDENETLIVS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTCCAGTTT GAGTCTAGGT TGGAGTTGGA GCCGTGGAGA TGCGGAAGGA AACCCCACCC 60
CCCCTAGTGC CCCCGGCGGC CCGGGAGTGG AATCTTCCCC CAAATGCGCC CGCCTGCATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0034709--C:methylosome
GO:0005654--C:nucleoplasm
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0008327--F:methyl-CpG binding
GO:0060770--P:negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0008284--P:positive regulation of cell proliferation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0060528--P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002192	Ailuropoda melanoleuca	91.30	1.00e-179	622.00
IUUC-Apl-003921	Anas platyrhynchos	63.16	8.00e-67	245.00
IUUC-Aca-004870	Anolis carolinensis	70.00	2.00e-119	421.00
IUUC-Ame-011872	Astyanax mexicanus	46.24	2.00e-38	151.00
IUUC-Bta-013325	Bos taurus	91.81	0.00e+00	626.00
IUUC-Cja-019059	Callithrix jacchus	96.78	0.00e+00	648.00
IUUC-Cfa-021036	Canis familiaris	91.07	7.00e-157	546.00
IUUC-Cpo-022369	Cavia porcellus	89.77	8.00e-177	612.00
IUUC-Csa-023585	Chlorocebus sabaeus	97.95	0.00e+00	657.00
IUUC-Cho-024470	Choloepus hoffmanni	82.57	7.00e-114	402.00
IUUC-Dno-029867	Dasypus novemcinctus	88.60	5.00e-177	613.00
IUUC-Dor-030834	Dipodomys ordii	64.14	6.00e-115	407.00
IUUC-Ete-032245	Echinops telfairi	82.47	4.00e-139	486.00
IUUC-Eca-033360	Equus caballus	91.23	9.00e-173	598.00
IUUC-Eeu-035353	Erinaceus europaeus	89.77	2.00e-176	611.00
IUUC-Fca-036277	Felis catus	92.40	0.00e+00	626.00
IUUC-Fal-037383	Ficedula albicollis	67.05	2.00e-102	365.00
IUUC-Gmo-038575	Gadus morhua	54.65	8.00e-101	360.00
IUUC-Gga-040658	Gallus gallus	69.63	3.00e-129	454.00
IUUC-Gac-041463	Gasterosteus aculeatus	52.04	3.00e-85	308.00
IUUC-Hsa-046247	Homo sapiens	99.12	0.00e+00	664.00
IUUC-Itr-048292	Ictidomys tridecemlineatus	93.86	1.00e-179	622.00
IUUC-Lch-049741	Latimeria chalumnae	65.51	8.00e-113	399.00
IUUC-Loc-052695	Lepisosteus oculatus	59.28	8.00e-107	379.00
IUUC-Laf-054535	Loxodonta africana	88.22	1.00e-174	605.00
IUUC-Mcc-054699	Macaca mulatta	97.95	0.00e+00	657.00
IUUC-Meu-056053	Macropus eugenii	75.80	4.00e-138	484.00
IUUC-Mga-059672	Meleagris gallopavo	64.95	7.00e-72	262.00
IUUC-Mmr-060963	Microcebus murinus	92.98	0.00e+00	635.00
IUUC-Mdo-062694	Monodelphis domestica	73.47	4.00e-132	464.00
IUUC-Mmu-064031	Mus musculus	88.89	2.00e-175	608.00
IUUC-Mpu-066408	Mustela putorius furo	91.81	0.00e+00	625.00
IUUC-Mlu-068184	Myotis lucifugus	89.21	1.00e-174	605.00
IUUC-Nle-069251	Nomascus leucogenys	97.66	0.00e+00	656.00
IUUC-Opr-071156	Ochotona princeps	84.50	7.00e-164	569.00
IUUC-Ont-072683	Oreochromis niloticus	57.32	5.00e-98	350.00
IUUC-Oan-073042	Ornithorhynchus anatinus	75.17	1.00e-125	442.00
IUUC-Ocu-074843	Oryctolagus cuniculus	92.71	9.00e-176	608.00
IUUC-Ola-086929	Oryzias latipes	53.23	4.00e-89	321.00
IUUC-Oga-088237	Otolemur garnettii	91.81	2.00e-180	624.00
IUUC-Oar-089312	Ovis aries	91.46	1.00e-164	572.00
IUUC-Ptr-091625	Pan troglodytes	99.12	0.00e+00	664.00
IUUC-Pan-091902	Papio anubis	93.02	2.00e-178	618.00
IUUC-Psi-094035	Pelodiscus sinensis	71.86	7.00e-127	446.00
IUUC-Pma-094565	Petromyzon marinus	64.04	2.00e-57	214.00
IUUC-Pfo-097070	Poecilia formosa	53.80	2.00e-92	332.00
IUUC-Pab-098007	Pongo abelii	99.12	0.00e+00	664.00
IUUC-Pca-100513	Procavia capensis	74.06	4.00e-104	370.00
IUUC-Pva-102821	Pteropus vampyrus	86.26	6.00e-165	573.00
IUUC-Rno-105836	Rattus norvegicus	87.93	2.00e-176	611.00
IUUC-Sha-106847	Sarcophilus harrisii	69.39	1.00e-87	315.00
IUUC-Sar-113451	Sorex araneus	84.55	3.00e-167	580.00
IUUC-Ssc-115978	Sus scrofa	90.64	5.00e-173	600.00
IUUC-Tgu-116745	Taeniopygia guttata	69.30	3.00e-95	340.00
IUUC-Tru-117945	Takifugu rubripes	52.48	2.00e-81	295.00
IUUC-Tsy-119059	Tarsius syrichta	88.14	3.00e-90	323.00
IUUC-Tni-120414	Tetraodon nigroviridis	54.29	1.00e-94	339.00
IUUC-Tbe-127559	Tupaia belangeri	94.44	0.00e+00	641.00
IUUC-Ttr-128505	Tursiops truncatus	89.47	6.00e-174	602.00
IUUC-Vpa-130350	Vicugna pacos	93.96	1.00e-100	358.00
IUUC-Xtr-132939	Xenopus tropicalis	60.00	4.00e-114	404.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence