iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048457

Ensembl Protein ID

ENSSTOP00000009067.2

UniProt Accession

I3MEU7; I3MEU7_ICTTR

Genbank Protein ID

ENSSTOP00000009067

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01088374

Gene Name

KEAP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000010114.2	ENSSTOT00000010107.2	ENSSTOP00000009067.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	9.80e-17	61.1	77	148
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	6.50e-09	35.0	181	211

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvv.....ggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +Dv+l+v        +f ahk+vLa+sS+vF+a+f+++l+e+   + v i+++ p+v++ l++F Yt ++++ 
   Q: 77   CDVTLQVkykdiPAAQFMAHKVVLASSSPVFKAMFTNGLREQG-MEVVSIEGIHPQVMERLIEFAYTASISMG 148
           89*****655444999*************************98.***********************998875 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++N++gi  fA++ +c +L+++a+++i  hF
   Q: 181  PSNAIGIANFAEQIGCAELHQRAREYIYMHF 211
           89****************************9 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MQPEPGPSRA GACSRFLPLC SQCPKGAGDA VMYASTECKA EVTPSQHGNR TFSYTLEDHT 60
KQAFGIMNEL RLSQQLCDVT LQVKYKDIPA AQFMAHKVVL ASSSPVFKAM FTNGLREQGM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGTATTGC CCCTTGTCAC CTGGAACCCC ATGCAGCCAG AACCTGGGCC TAGCAGGGCT 60
GGGGCCTGCA GCCGATTCCT GCCCCTGTGT TCACAGTGCC CCAAGGGGGC AGGGGACGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR030563--KEAP1
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005884--C:actin filament
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0005815--C:microtubule organizing center
GO:0030496--C:midbody
GO:0005654--C:nucleoplasm
GO:0071353--P:cellular response to interleukin-4
GO:0001701--P:in utero embryonic development
GO:0010499--P:proteasomal ubiquitin-independent protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0045604--P:regulation of epidermal cell differentiation
GO:0006355--P:regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001377	Ailuropoda melanoleuca	97.28	0.00e+00	1269.00
IUUC-Aca-005389	Anolis carolinensis	86.17	0.00e+00	1084.00
IUUC-Ame-010749	Astyanax mexicanus	78.57	0.00e+00	974.00
IUUC-Bta-013505	Bos taurus	96.63	0.00e+00	1263.00
IUUC-Cja-018823	Callithrix jacchus	96.96	0.00e+00	1270.00
IUUC-Cfa-021202	Canis familiaris	97.28	0.00e+00	1272.00
IUUC-Cpo-021830	Cavia porcellus	96.84	0.00e+00	845.00
IUUC-Csa-023728	Chlorocebus sabaeus	97.28	0.00e+00	1274.00
IUUC-Cin-025195	Ciona intestinalis	55.00	0.00e+00	674.00
IUUC-Csv-026155	Ciona savignyi	53.94	2.00e-180	625.00
IUUC-Dre-027388	Danio rerio	77.08	0.00e+00	949.00
IUUC-Dno-029066	Dasypus novemcinctus	85.28	0.00e+00	1086.00
IUUC-Dor-030674	Dipodomys ordii	95.13	0.00e+00	832.00
IUUC-Dme-032165	Drosophila melanogaster	49.38	2.00e-161	562.00
IUUC-Ete-032255	Echinops telfairi	92.86	2.00e-97	348.00
IUUC-Eca-034381	Equus caballus	93.43	0.00e+00	1203.00
IUUC-Eeu-034791	Erinaceus europaeus	92.36	0.00e+00	819.00
IUUC-Fca-036067	Felis catus	96.96	0.00e+00	1266.00
IUUC-Gmo-039691	Gadus morhua	77.21	0.00e+00	956.00
IUUC-Gga-040266	Gallus gallus	79.53	0.00e+00	997.00
IUUC-Gac-041866	Gasterosteus aculeatus	77.46	0.00e+00	960.00
IUUC-Ggo-044719	Gorilla gorilla	97.28	0.00e+00	1273.00
IUUC-Hsa-046255	Homo sapiens	97.28	0.00e+00	1273.00
IUUC-Lch-049646	Latimeria chalumnae	83.05	0.00e+00	1040.00
IUUC-Loc-052296	Lepisosteus oculatus	57.32	0.00e+00	646.00
IUUC-Laf-054579	Loxodonta africana	97.28	0.00e+00	1275.00
IUUC-Mcc-055315	Macaca mulatta	97.28	0.00e+00	1274.00
IUUC-Meu-056288	Macropus eugenii	88.46	0.00e+00	1130.00
IUUC-Mmr-061639	Microcebus murinus	96.79	0.00e+00	1270.00
IUUC-Mdo-062072	Monodelphis domestica	94.39	0.00e+00	1231.00
IUUC-Mmu-063622	Mus musculus	93.75	0.00e+00	1233.00
IUUC-Mpu-066737	Mustela putorius furo	94.71	0.00e+00	1229.00
IUUC-Mlu-068173	Myotis lucifugus	96.63	0.00e+00	1264.00
IUUC-Nle-069336	Nomascus leucogenys	57.55	0.00e+00	632.00
IUUC-Opr-070432	Ochotona princeps	96.83	0.00e+00	1222.00
IUUC-Ont-072160	Oreochromis niloticus	77.65	0.00e+00	955.00
IUUC-Oan-072691	Ornithorhynchus anatinus	80.34	0.00e+00	979.00
IUUC-Ocu-073798	Oryctolagus cuniculus	96.47	0.00e+00	1264.00
IUUC-Ola-086367	Oryzias latipes	74.54	0.00e+00	918.00
IUUC-Oga-088231	Otolemur garnettii	96.96	0.00e+00	1268.00
IUUC-Oar-089227	Ovis aries	95.35	0.00e+00	1239.00
IUUC-Ptr-091460	Pan troglodytes	97.28	0.00e+00	1273.00
IUUC-Pan-092713	Papio anubis	97.28	0.00e+00	1274.00
IUUC-Pfo-096468	Poecilia formosa	78.27	0.00e+00	959.00
IUUC-Pab-098357	Pongo abelii	97.44	0.00e+00	1276.00
IUUC-Pca-100837	Procavia capensis	96.15	0.00e+00	1255.00
IUUC-Pva-103249	Pteropus vampyrus	94.71	0.00e+00	1208.00
IUUC-Rno-106086	Rattus norvegicus	93.27	0.00e+00	1221.00
IUUC-Sha-107245	Sarcophilus harrisii	93.91	0.00e+00	1226.00
IUUC-Sar-112985	Sorex araneus	95.67	0.00e+00	1257.00
IUUC-Ssc-115756	Sus scrofa	97.44	0.00e+00	1273.00
IUUC-Tgu-116838	Taeniopygia guttata	53.93	2.00e-118	418.00
IUUC-Tru-117644	Takifugu rubripes	77.82	0.00e+00	979.00
IUUC-Tni-120245	Tetraodon nigroviridis	78.02	0.00e+00	966.00
IUUC-Tbe-127472	Tupaia belangeri	98.37	5.00e-149	521.00
IUUC-Ttr-128953	Tursiops truncatus	95.81	0.00e+00	705.00
IUUC-Vpa-130683	Vicugna pacos	94.02	0.00e+00	1097.00
IUUC-Xtr-132827	Xenopus tropicalis	76.11	0.00e+00	951.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence