iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-022152

Ensembl Protein ID

ENSCPOP00000010779.2

UniProt Accession

H0VKF2; H0VKF2_CAVPO

Genbank Protein ID

ENSCPOP00000010779

Protein Name

DNA repair protein REV1

Genbank Nucleotide ID

AAKN02027879

Gene Name

REV1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000011981.3	ENSCPOT00000012097.2	ENSCPOP00000010779.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBM	2.50e-19	68.2	1007	1035

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBM

   S: 1    lPsqvDpeVfsqLPeeiQeEvmaelrqqk 29
           ++sqvDpeVf++LP+e+Q+E++a+++q++
   Q: 1007 AFSQVDPEVFAALPAELQKELKAAYDQRQ 1035
           59*************************98 PP

Organism

Cavia porcellus

Functional Description
(View)

Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.

Protein Sequence
(Fasta)

MRRGGWRKRA ENDWEKWGGY MAAKVQKLEQ QFRSDAALQK DGTSSTIFSG VAIYVNGYTD 60
PSAEELRKLM MLHGGQYHVY YSRSKTTHII ATNLPTAKIK ELKGEKVIRP EWIVESIKAG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGGCGAG GTGGATGGAG GAAGCGAGCT GAAAATGACT GGGAAAAATG GGTGTGTTTT 60
GAAGAATAAA AATAATTATA TCAGAATAGC TAGTTTTTTC TCATTTTTCT TTTAGTTTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0237--DNA synthesis
KW-0238--DNA-binding
KW-0548--Nucleotidyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR001357--BRCT_dom
IPR017961--DNA_pol_Y-fam_little_finger
IPR025527--DUF4414
IPR012112--REV1
IPR031991--Rev1_C
IPR001126--UmuC

PROSITE

PS50172--BRCT
PS50173--UMUC

Pfam

PF16589--BRCT_2
PF14377--DUF4414
PF00817--IMS
PF11799--IMS_C
PF16727--REV1_C

SMART

SM00292--BRCT

Gene Ontology

GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0017125--F:deoxycytidyl transferase activity
GO:0042276--P:error-prone translesion synthesis
GO:0009411--P:response to UV

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000375	Aegilops tauschii	28.87	4.00e-30	127.00
IUUC-Aml-001185	Ailuropoda melanoleuca	83.33	0.00e+00	2044.00
IUUC-Atr-002915	Amborella trichopoda	35.92	2.00e-82	301.00
IUUC-Apl-004054	Anas platyrhynchos	72.18	0.00e+00	1721.00
IUUC-Aca-004304	Anolis carolinensis	67.06	0.00e+00	1608.00
IUUC-Aly-005696	Arabidopsis lyrata	33.90	2.00e-83	304.00
IUUC-Ath-006893	Arabidopsis thaliana	33.21	5.00e-84	306.00
IUUC-Ago-007722	Ashbya gossypii	28.74	5.00e-41	162.00
IUUC-Acl-008347	Aspergillus clavatus	36.25	8.00e-86	312.00
IUUC-Afl-008444	Aspergillus flavus	36.71	9.00e-88	318.00
IUUC-Afu-008837	Aspergillus fumigatus	31.68	5.00e-85	309.00
IUUC-Ani-009188	Aspergillus nidulans	38.37	6.00e-91	329.00
IUUC-Ang-009866	Aspergillus niger	34.43	6.00e-95	342.00
IUUC-Aor-010107	Aspergillus oryzae	36.71	1.00e-87	318.00
IUUC-Ate-010359	Aspergillus terreus	32.97	1.00e-91	331.00
IUUC-Ame-010664	Astyanax mexicanus	48.68	0.00e+00	1090.00
IUUC-Bgr-012244	Blumeria graminis	28.51	3.00e-84	306.00
IUUC-Bta-013405	Bos taurus	77.57	0.00e+00	1748.00
IUUC-Bci-013849	Botrytis cinerea	31.85	1.00e-87	318.00
IUUC-Bdi-014066	Brachypodium distachyon	36.70	2.00e-84	307.00
IUUC-Bol-015544	Brassica oleracea	34.71	2.00e-85	311.00
IUUC-Bra-017792	Brassica rapa	32.82	6.00e-82	299.00
IUUC-Cel-018148	Caenorhabditis elegans	32.70	5.00e-82	299.00
IUUC-Cja-019742	Callithrix jacchus	73.43	0.00e+00	1473.00
IUUC-Cfa-020112	Canis familiaris	83.81	0.00e+00	2072.00
IUUC-Cre-022951	Chlamydomonas reinhardtii	41.42	2.00e-39	157.00
IUUC-Csa-023504	Chlorocebus sabaeus	84.42	0.00e+00	2088.00
IUUC-Cho-024780	Choloepus hoffmanni	65.71	0.00e+00	713.00
IUUC-Cin-025276	Ciona intestinalis	41.01	2.00e-106	379.00
IUUC-Csv-026283	Ciona savignyi	43.51	1.00e-114	406.00
IUUC-Cgl-026726	Colletotrichum gloeosporioides	27.97	1.00e-89	325.00
IUUC-Cne-027079	Cryptococcus neoformans	32.54	4.00e-75	276.00
IUUC-Cme-027346	Cyanidioschyzon merolae	28.08	5.00e-46	179.00
IUUC-Dre-028073	Danio rerio	49.21	0.00e+00	1081.00
IUUC-Dno-030038	Dasypus novemcinctus	78.61	0.00e+00	1922.00
IUUC-Dor-031100	Dipodomys ordii	79.94	0.00e+00	1470.00
IUUC-Dse-031310	Dothistroma septosporum	29.67	3.00e-85	310.00
IUUC-Dme-031991	Drosophila melanogaster	41.55	3.00e-112	399.00
IUUC-Ete-033082	Echinops telfairi	73.33	0.00e+00	1351.00
IUUC-Eca-033471	Equus caballus	84.13	0.00e+00	2050.00
IUUC-Eeu-034993	Erinaceus europaeus	81.49	0.00e+00	1362.00
IUUC-Fca-035367	Felis catus	83.11	0.00e+00	1988.00
IUUC-Fal-036973	Ficedula albicollis	72.62	0.00e+00	1678.00
IUUC-Fox-037677	Fusarium oxysporum	30.64	2.00e-88	320.00
IUUC-Fso-038252	Fusarium solani	31.23	5.00e-92	332.00
IUUC-Gmo-039669	Gadus morhua	52.57	0.00e+00	824.00
IUUC-Ggr-039988	Gaeumannomyces graminis	29.93	1.00e-85	311.00
IUUC-Gga-040423	Gallus gallus	72.58	0.00e+00	1717.00
IUUC-Gac-042134	Gasterosteus aculeatus	49.27	0.00e+00	776.00
IUUC-Gma-042929	Glycine max	36.76	2.00e-86	313.00
IUUC-Ggo-044528	Gorilla gorilla	84.84	0.00e+00	2086.00
IUUC-Hsa-046259	Homo sapiens	84.76	0.00e+00	2060.00
IUUC-Hvu-047139	Hordeum vulgare	36.47	3.00e-57	216.00
IUUC-Itr-048621	Ictidomys tridecemlineatus	84.92	0.00e+00	2114.00
IUUC-Kpa-049169	Komagataella pastoris	29.49	6.00e-63	236.00
IUUC-Lch-050471	Latimeria chalumnae	62.83	0.00e+00	1483.00
IUUC-Lpe-050800	Leersia perrieri	28.45	2.00e-89	323.00
IUUC-Loc-052320	Lepisosteus oculatus	46.89	0.00e+00	917.00
IUUC-Lma-053149	Leptosphaeria maculans	29.92	2.00e-87	317.00
IUUC-Laf-053810	Loxodonta africana	79.29	0.00e+00	1887.00
IUUC-Mcc-055574	Macaca mulatta	84.76	0.00e+00	2048.00
IUUC-Meu-055945	Macropus eugenii	61.80	0.00e+00	1084.00
IUUC-Mor-057195	Magnaporthe oryzae	30.79	4.00e-92	333.00
IUUC-Mpo-057488	Magnaporthe poae	31.63	8.00e-86	312.00
IUUC-Mtr-057955	Medicago truncatula	35.91	5.00e-87	316.00
IUUC-Mla-059027	Melampsora laricipopulina	36.29	2.00e-81	297.00
IUUC-Mga-060156	Meleagris gallopavo	72.73	0.00e+00	1734.00
IUUC-Mvi-060398	Microbotryum violaceum	35.83	2.00e-81	297.00
IUUC-Mmr-061113	Microcebus murinus	85.17	0.00e+00	2070.00
IUUC-Mdo-063001	Monodelphis domestica	77.76	0.00e+00	1880.00
IUUC-Mmu-063180	Mus musculus	81.45	0.00e+00	1978.00
IUUC-Mac-065551	Musa acuminata	36.60	3.00e-53	203.00
IUUC-Mpu-066525	Mustela putorius furo	83.33	0.00e+00	2040.00
IUUC-Mlu-067877	Myotis lucifugus	81.58	0.00e+00	1986.00
IUUC-Nfi-068418	Neosartorya fischeri	32.23	7.00e-86	312.00
IUUC-Ncr-068648	Neurospora crassa	32.09	6.00e-89	322.00
IUUC-Nle-069959	Nomascus leucogenys	84.84	0.00e+00	2066.00
IUUC-Opr-070522	Ochotona princeps	80.08	0.00e+00	1149.00
IUUC-Ont-072293	Oreochromis niloticus	44.28	0.00e+00	993.00
IUUC-Oan-073519	Ornithorhynchus anatinus	75.89	0.00e+00	1837.00
IUUC-Ocu-074492	Oryctolagus cuniculus	81.71	0.00e+00	1879.00
IUUC-Oba-075567	Oryza barthii	28.10	1.00e-87	318.00
IUUC-Obr-076332	Oryza brachyantha	36.63	1.00e-87	318.00
IUUC-Ogl-077348	Oryza glaberrima	28.44	7.00e-89	322.00
IUUC-Ogu-078779	Oryza glumaepatula	27.91	3.00e-87	317.00
IUUC-Oin-079738	Oryza indica	26.91	9.00e-77	281.00
IUUC-Olo-080701	Oryza longistaminata	27.00	2.00e-76	280.00
IUUC-Ome-081708	Oryza meridionalis	28.63	3.00e-85	310.00
IUUC-Oni-082251	Oryza nivara	34.13	5.00e-85	309.00
IUUC-Opu-083528	Oryza punctata	31.33	2.00e-79	291.00
IUUC-Oru-084293	Oryza rufipogon	27.77	1.00e-82	301.00
IUUC-Osa-085549	Oryza sativa	28.44	2.00e-88	321.00
IUUC-Ola-086793	Oryzias latipes	47.53	0.00e+00	822.00
IUUC-Olu-087786	Ostreococcus lucimarinus	29.67	5.00e-59	222.00
IUUC-Oga-089006	Otolemur garnettii	84.43	0.00e+00	2048.00
IUUC-Oar-089597	Ovis aries	78.79	0.00e+00	1920.00
IUUC-Ptr-091520	Pan troglodytes	84.84	0.00e+00	2061.00
IUUC-Pan-092333	Papio anubis	84.76	0.00e+00	2031.00
IUUC-Psi-094004	Pelodiscus sinensis	73.60	0.00e+00	1791.00
IUUC-Pma-094128	Petromyzon marinus	53.77	9.00e-94	337.00
IUUC-Pno-094849	Phaeosphaeria nodorum	29.35	6.00e-82	299.00
IUUC-Ppa-095714	Physcomitrella patens	27.77	1.00e-90	328.00
IUUC-Pfo-096569	Poecilia formosa	46.53	0.00e+00	993.00
IUUC-Pab-097960	Pongo abelii	84.36	0.00e+00	2054.00
IUUC-Pop-098921	Populus trichocarpa	35.44	2.00e-81	297.00
IUUC-Pca-100509	Procavia capensis	65.39	0.00e+00	1116.00
IUUC-Ppe-101730	Prunus persica	36.40	1.00e-88	321.00
IUUC-Pva-102142	Pteropus vampyrus	80.86	0.00e+00	1938.00
IUUC-Pgr-103446	Puccinia graminis	31.21	5.00e-69	255.00
IUUC-Ptt-103849	Puccinia triticina	30.48	3.00e-73	271.00
IUUC-Pte-104128	Pyrenophora teres	31.14	4.00e-84	306.00
IUUC-Pyt-104754	Pyrenophora triticirepentis	32.17	1.00e-82	301.00
IUUC-Rno-104871	Rattus norvegicus	80.18	0.00e+00	1945.00
IUUC-Sce-106236	Saccharomyces cerevisiae	26.58	5.00e-41	163.00
IUUC-Sha-106962	Sarcophilus harrisii	76.80	0.00e+00	1869.00
IUUC-Sja-107691	Schizosaccharomyces japonicus	27.40	7.00e-66	245.00
IUUC-Spo-108170	Schizosaccharomyces pombe	33.68	1.00e-63	238.00
IUUC-Ssl-108668	Sclerotinia sclerotiorum	31.25	2.00e-90	327.00
IUUC-Smo-109554	Selaginella moellendorffii	36.61	4.00e-84	306.00
IUUC-Sit-110479	Setaria italica	41.39	6.00e-69	256.00
IUUC-Sly-111752	Solanum lycopersicum	35.49	4.00e-90	326.00
IUUC-Sar-113304	Sorex araneus	81.10	0.00e+00	1940.00
IUUC-Sbi-114196	Sorghum bicolor	40.73	2.00e-68	254.00
IUUC-Sre-115151	Sporisorium reilianum	33.04	6.00e-84	306.00
IUUC-Ssc-116104	Sus scrofa	81.35	0.00e+00	1992.00
IUUC-Tgu-117438	Taeniopygia guttata	73.11	0.00e+00	1724.00
IUUC-Tru-118553	Takifugu rubripes	46.88	0.00e+00	977.00
IUUC-Tsy-119056	Tarsius syrichta	80.49	0.00e+00	1893.00
IUUC-Tni-119933	Tetraodon nigroviridis	46.67	0.00e+00	944.00
IUUC-Tca-121376	Theobroma cacao	31.57	1.00e-108	388.00
IUUC-Tre-121972	Trichoderma reesei	27.21	9.00e-82	298.00
IUUC-Tvi-122342	Trichoderma virens	31.47	5.00e-81	296.00
IUUC-Tae-123898	Triticum aestivum	35.04	4.00e-86	313.00
IUUC-Tur-126735	Triticum urartu	35.98	1.00e-33	139.00
IUUC-Tme-126999	Tuber melanosporum	31.77	8.00e-80	292.00
IUUC-Tbe-127280	Tupaia belangeri	83.17	2.00e-132	467.00
IUUC-Ttr-129104	Tursiops truncatus	81.90	0.00e+00	1984.00
IUUC-Uma-129562	Ustilago maydis	31.41	5.00e-88	319.00
IUUC-Vda-129862	Verticillium dahliae	30.80	7.00e-91	329.00
IUUC-Vpa-130819	Vicugna pacos	80.65	0.00e+00	1048.00
IUUC-Vvi-131111	Vitis vinifera	34.74	7.00e-83	302.00
IUUC-Xtr-132629	Xenopus tropicalis	59.06	0.00e+00	1357.00
IUUC-Xma-134065	Xiphophorus maculatus	50.86	0.00e+00	805.00
IUUC-Yli-134633	Yarrowia lipolytica	33.60	3.00e-64	240.00
IUUC-Zma-135176	Zea mays	35.05	3.00e-84	306.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence