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Tag Content
iUUCD ID IUUC-Ocu-074016
Ensembl Protein ID ENSOCUP00000001884.2
UniProt Accession G1SH00; G1SH00_RABIT
Protein Name Uncharacterized protein
Gene Name PML
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOCUG00000002183.3 ENSOCUT00000002182.3 ENSOCUP00000001884.2
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 65.91 0.00e+00 1043.00 IUUC-Hsa-045861
E3 activity/RING/RING 59.21 0.00e+00 879.00 IUUC-Mmu-063118
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Oryctolagus cuniculus
Protein Sequence
(Fasta)
MQQDPAPAGS PGSQRDAGPT RTPTMASPEL RSEGAPRSPS PAEQAEEEDF QFLQCQGCHT 60
QAKCPKLLPC LHTLCSGCLE APGLHCPICQ GPRALDGAPV LDNIFFESLQ RRLAVHQQVV 120
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Protein Fasta Sequence



>IUUC-Ocu-074016|E3,RING|Oryctolagus cuniculus
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Nucleotide Sequence
(Fasta)
ATGCAGCAGG ATCCCGCGCC CGCCGGGTCC CCGGGCTCCC AGCGCGACGC CGGCCCGACC 60
CGCACCCCCA CCATGGCGTC CCCGGAGTTG CGCTCCGAAG GTGCCCCACG TAGCCCCAGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Ocu-074016|E3,RING|Oryctolagus cuniculus
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Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR021978--DUF3583
IPR012337--RNaseH-like_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF12126--DUF3583
PF00643--zf-B_box

SMART

SM00336--BBOX

Gene Ontology

GO:0005829--C:cytosol
GO:0042406--C:extrinsic component of endoplasmic reticulum membrane
GO:0000784--C:nuclear chromosome, telomeric region
GO:0016363--C:nuclear matrix
GO:0031965--C:nuclear membrane
GO:0005730--C:nucleolus
GO:0016605--C:PML body
GO:0008270--F:zinc ion binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0007050--P:cell cycle arrest
GO:0045165--P:cell fate commitment
GO:0071353--P:cellular response to interleukin-4
GO:0090398--P:cellular senescence
GO:0032922--P:circadian regulation of gene expression
GO:0007182--P:common-partner SMAD protein phosphorylation
GO:0006977--P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0032469--P:endoplasmic reticulum calcium ion homeostasis
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0097191--P:extrinsic apoptotic signaling pathway
GO:0010761--P:fibroblast migration
GO:0045087--P:innate immune response
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0070059--P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0008631--P:intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0051457--P:maintenance of protein location in nucleus
GO:0030099--P:myeloid cell differentiation
GO:0016525--P:negative regulation of angiogenesis
GO:0030308--P:negative regulation of cell growth
GO:0008285--P:negative regulation of cell proliferation
GO:0050713--P:negative regulation of interleukin-1 beta secretion
GO:2000059--P:negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:1902187--P:negative regulation of viral release from host cell
GO:0030578--P:PML body organization
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:0048146--P:positive regulation of fibroblast proliferation
GO:0045345--P:positive regulation of MHC class I biosynthetic process
GO:0032206--P:positive regulation of telomere maintenance
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0006461--P:protein complex assembly
GO:0010522--P:regulation of calcium ion transport into cytosol
GO:0030155--P:regulation of cell adhesion
GO:2000779--P:regulation of double-strand break repair
GO:0001932--P:regulation of protein phosphorylation
GO:0010332--P:response to gamma radiation
GO:0001666--P:response to hypoxia
GO:0009411--P:response to UV
GO:0048384--P:retinoic acid receptor signaling pathway
GO:0007184--P:SMAD protein import into nucleus
GO:0007179--P:transforming growth factor beta receptor signaling pathway

KEGG ocu:100351382
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001901 Ailuropoda melanoleuca 67.64 0.00e+00 993.00
IUUC-Bta-012427 Bos taurus 65.94 0.00e+00 1062.00
IUUC-Cja-019029 Callithrix jacchus 69.49 0.00e+00 1073.00
IUUC-Cfa-021127 Canis familiaris 68.15 0.00e+00 1022.00
IUUC-Cpo-022553 Cavia porcellus 63.95 0.00e+00 906.00
IUUC-Csa-023187 Chlorocebus sabaeus 68.55 0.00e+00 747.00
IUUC-Cho-024937 Choloepus hoffmanni 61.40 2.00e-84 306.00
IUUC-Dno-029326 Dasypus novemcinctus 69.33 0.00e+00 997.00
IUUC-Dor-030808 Dipodomys ordii 59.30 0.00e+00 634.00
IUUC-Ete-032746 Echinops telfairi 65.57 6.00e-76 278.00
IUUC-Eca-033234 Equus caballus 67.53 0.00e+00 991.00
IUUC-Fca-035648 Felis catus 69.93 0.00e+00 1078.00
IUUC-Ggo-044927 Gorilla gorilla 69.08 0.00e+00 1088.00
IUUC-Hsa-045861 Homo sapiens 69.08 0.00e+00 1086.00
IUUC-Itr-047861 Ictidomys tridecemlineatus 68.52 0.00e+00 1100.00
IUUC-Loc-052276 Lepisosteus oculatus 35.40 2.00e-48 187.00
IUUC-Laf-054059 Loxodonta africana 65.73 0.00e+00 1011.00
IUUC-Meu-056495 Macropus eugenii 51.91 8.00e-99 354.00
IUUC-Mga-059224 Meleagris gallopavo 42.04 3.00e-39 157.00
IUUC-Mmr-061507 Microcebus murinus 66.12 0.00e+00 1028.00
IUUC-Mdo-062196 Monodelphis domestica 44.57 2.00e-175 609.00
IUUC-Mmu-063118 Mus musculus 60.27 0.00e+00 959.00
IUUC-Mpu-066024 Mustela putorius furo 64.09 0.00e+00 971.00
IUUC-Mlu-066980 Myotis lucifugus 64.78 0.00e+00 979.00
IUUC-Nle-069779 Nomascus leucogenys 69.34 0.00e+00 1045.00
IUUC-Oga-089085 Otolemur garnettii 59.86 0.00e+00 934.00
IUUC-Oar-089980 Ovis aries 64.15 0.00e+00 1010.00
IUUC-Ptr-091681 Pan troglodytes 69.04 0.00e+00 1085.00
IUUC-Pan-091965 Papio anubis 67.50 0.00e+00 1046.00
IUUC-Psi-093577 Pelodiscus sinensis 37.64 5.00e-110 392.00
IUUC-Pab-098215 Pongo abelii 65.70 2.00e-168 586.00
IUUC-Pca-100883 Procavia capensis 63.95 0.00e+00 725.00
IUUC-Pva-102465 Pteropus vampyrus 62.26 0.00e+00 702.00
IUUC-Rno-105120 Rattus norvegicus 60.41 0.00e+00 987.00
IUUC-Sar-113320 Sorex araneus 56.66 3.00e-74 273.00
IUUC-Ssc-116042 Sus scrofa 65.30 0.00e+00 1067.00
IUUC-Tbe-127880 Tupaia belangeri 66.12 4.00e-129 455.00
Created Date 25-Jun-2017

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