iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066577

Ensembl Protein ID

ENSMPUP00000010925.1

UniProt Accession

M3YHW8; M3YHW8_MUSPF

Genbank Protein ID

ENSMPUP00000010925

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01103171

Gene Name

WDR61

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000011014.1	ENSMPUT00000011107.1	ENSMPUP00000010925.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-43	145.4	230	269
UBD/Beta-Prp	4.40e-74	249.3	12	303

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+++v  +af +d t++vs+s D+++kvWD+ t +++++
   Q: 230  GHASWVLNVAFcPDdTHFVSSSSDKSVKVWDVGTRTCVHT 269
           8***********777*****************99999875 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkf....spdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvh 88
           +++h++ i +v++    ++ ++ ++tgs d+ +kvw+++++ l   +sl+gh+ +v +v++s++ +i +++s D++i++wdl++gk++ 
   Q: 12   EQAHDDAIWSVAWgtdkKEISETVVTGSLDDLVKVWKWSDERLdlQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQIK 100
           56777777778887655566789******************99999******************************************* PP
   S: 89   tlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltg 177
           ++ +   ++++l+fsp++++l++G+h+  ++++ +e+g++ +  l+ + +++ +++++pdg++l+sG+ D++++++d++tgkll+tl+g
   Q: 101  SIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEY-SLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEG 188
           ******************************************.*********************************************9 PP
   S: 178  ghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
            h  +++sl+f+++++ lv++s+dg++k++d+q+ +   tl gh ++v+ v+f+p+d+++vs ssD+s+++Wd+ ++++++t+  h+++
   Q: 189  -HAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQ 276
           .**************************************************************************************** PP
   S: 267  visvavlsfgdnvlvlgsedskvniwkl 294
           v+ v++ + +++++v++++d++++++++
   Q: 277  VWGVKY-NGNGSKIVSVGDDQEIHVYDC 303
           ******.999****************97 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MTNQYSILFK QEQAHDDAIW SVAWGTDKKE ISETVVTGSL DDLVKVWKWS DERLDLQWSL 60
EGHQLGVVSV DISHTLPIAA SSSLDAHIRL WDLENGKQIK SIDAGPVDAW TLAFSPDSQY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGCGAGATG CCCCGCCCCC GCGTCGTAGC TCATCGCTGC GCGACGCTGT CGCCGCGAGC 60
CGCGCGTCAC AAGCGCGGCG ACCGTGCAGC CGGCAGGACG GCGGTGAGTT GACGCGCGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016593--C:Cdc73/Paf1 complex
GO:0005829--C:cytosol
GO:0055087--C:Ski complex
GO:0035327--C:transcriptionally active chromatin
GO:0080182--P:histone H3-K4 trimethylation
GO:0045638--P:negative regulation of myeloid cell differentiation
GO:0051571--P:positive regulation of histone H3-K4 methylation
GO:2001162--P:positive regulation of histone H3-K79 methylation
GO:0032968--P:positive regulation of transcription elongation from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000774	Aegilops tauschii	34.12	2.00e-47	182.00
IUUC-Aml-002245	Ailuropoda melanoleuca	99.34	5.00e-168	583.00
IUUC-Atr-003142	Amborella trichopoda	51.55	2.00e-38	151.00
IUUC-Apl-003179	Anas platyrhynchos	90.49	4.00e-156	543.00
IUUC-Aca-004880	Anolis carolinensis	88.85	4.00e-157	546.00
IUUC-Aly-005956	Arabidopsis lyrata	37.50	8.00e-55	207.00
IUUC-Ath-007230	Arabidopsis thaliana	37.18	1.00e-50	193.00
IUUC-Acl-008297	Aspergillus clavatus	28.88	4.00e-25	108.00
IUUC-Ang-009702	Aspergillus niger	30.23	1.00e-30	126.00
IUUC-Ame-011511	Astyanax mexicanus	84.04	5.00e-149	520.00
IUUC-Bgr-012189	Blumeria graminis	30.47	8.00e-29	120.00
IUUC-Bta-012936	Bos taurus	97.70	2.00e-166	577.00
IUUC-Bdi-015020	Brachypodium distachyon	37.59	3.00e-47	181.00
IUUC-Bol-016345	Brassica oleracea	38.78	4.00e-56	211.00
IUUC-Bra-017323	Brassica rapa	38.78	3.00e-56	211.00
IUUC-Cja-019961	Callithrix jacchus	98.03	2.00e-166	578.00
IUUC-Cfa-020862	Canis familiaris	98.69	8.00e-167	579.00
IUUC-Cpo-021356	Cavia porcellus	98.34	5.00e-165	573.00
IUUC-Cre-022602	Chlamydomonas reinhardtii	42.30	9.00e-58	216.00
IUUC-Csa-024067	Chlorocebus sabaeus	97.70	6.00e-166	576.00
IUUC-Cho-024421	Choloepus hoffmanni	82.83	1.00e-82	298.00
IUUC-Cin-025261	Ciona intestinalis	64.26	8.00e-116	409.00
IUUC-Cgl-026446	Colletotrichum gloeosporioides	28.30	4.00e-29	121.00
IUUC-Cne-026846	Cryptococcus neoformans	29.55	9.00e-25	107.00
IUUC-Dre-027706	Danio rerio	65.90	6.00e-110	390.00
IUUC-Dno-029084	Dasypus novemcinctus	97.72	1.00e-165	575.00
IUUC-Dor-030353	Dipodomys ordii	82.61	6.00e-122	429.00
IUUC-Dse-031348	Dothistroma septosporum	31.03	4.00e-26	112.00
IUUC-Dme-031836	Drosophila melanogaster	52.62	2.00e-88	318.00
IUUC-Ete-032261	Echinops telfairi	94.75	1.00e-159	555.00
IUUC-Eca-034231	Equus caballus	90.16	5.00e-151	526.00
IUUC-Eeu-034828	Erinaceus europaeus	97.59	3.00e-155	540.00
IUUC-Fca-036569	Felis catus	98.69	4.00e-167	580.00
IUUC-Fal-037469	Ficedula albicollis	92.46	8.00e-160	555.00
IUUC-Fox-038047	Fusarium oxysporum	33.00	1.00e-29	123.00
IUUC-Gmo-039579	Gadus morhua	83.93	5.00e-146	509.00
IUUC-Gga-040808	Gallus gallus	93.15	4.00e-153	533.00
IUUC-Gac-042100	Gasterosteus aculeatus	84.26	3.00e-147	513.00
IUUC-Gma-043509	Glycine max	40.94	5.00e-59	221.00
IUUC-Ggo-045227	Gorilla gorilla	98.03	2.00e-166	578.00
IUUC-Hsa-045839	Homo sapiens	98.03	2.00e-166	578.00
IUUC-Hvu-047591	Hordeum vulgare	38.17	2.00e-49	189.00
IUUC-Itr-048741	Ictidomys tridecemlineatus	98.36	4.00e-167	580.00
IUUC-Lch-049549	Latimeria chalumnae	83.93	5.00e-147	513.00
IUUC-Lpe-050746	Leersia perrieri	38.59	7.00e-48	184.00
IUUC-Loc-052540	Lepisosteus oculatus	87.21	7.00e-149	519.00
IUUC-Lma-052992	Leptosphaeria maculans	28.14	1.00e-27	116.00
IUUC-Laf-053907	Loxodonta africana	98.36	4.00e-167	580.00
IUUC-Mcc-055828	Macaca mulatta	91.69	3.00e-162	563.00
IUUC-Meu-056075	Macropus eugenii	94.49	8.00e-135	472.00
IUUC-Mtr-057728	Medicago truncatula	40.71	3.00e-56	212.00
IUUC-Mga-059872	Meleagris gallopavo	92.79	2.00e-160	557.00
IUUC-Mvi-060564	Microbotryum violaceum	32.11	3.00e-29	122.00
IUUC-Mmr-060985	Microcebus murinus	97.95	2.00e-158	551.00
IUUC-Mdo-062758	Monodelphis domestica	89.80	5.00e-157	546.00
IUUC-Mmu-063580	Mus musculus	96.72	1.00e-164	571.00
IUUC-Mac-064880	Musa acuminata	40.19	2.00e-57	215.00
IUUC-Nle-069573	Nomascus leucogenys	98.03	2.00e-166	578.00
IUUC-Opr-070216	Ochotona princeps	98.01	2.00e-163	568.00
IUUC-Ont-071981	Oreochromis niloticus	85.57	5.00e-150	523.00
IUUC-Oan-073223	Ornithorhynchus anatinus	93.94	9.00e-108	382.00
IUUC-Ocu-074199	Oryctolagus cuniculus	84.59	1.00e-138	485.00
IUUC-Oba-075255	Oryza barthii	40.00	2.00e-41	162.00
IUUC-Obr-076168	Oryza brachyantha	47.20	1.00e-35	143.00
IUUC-Ogl-077777	Oryza glaberrima	38.59	1.00e-48	186.00
IUUC-Ogu-078780	Oryza glumaepatula	38.59	1.00e-48	186.00
IUUC-Oin-079228	Oryza indica	38.59	3.00e-51	195.00
IUUC-Olo-080617	Oryza longistaminata	45.77	3.00e-29	120.00
IUUC-Ome-081421	Oryza meridionalis	38.59	8.00e-48	183.00
IUUC-Oni-082997	Oryza nivara	38.59	3.00e-51	195.00
IUUC-Opu-083931	Oryza punctata	38.91	1.00e-48	186.00
IUUC-Oru-084645	Oryza rufipogon	38.59	1.00e-48	186.00
IUUC-Osa-085842	Oryza sativa	38.59	3.00e-51	195.00
IUUC-Ola-086696	Oryzias latipes	85.25	6.00e-146	509.00
IUUC-Olu-087643	Ostreococcus lucimarinus	39.91	2.00e-41	162.00
IUUC-Oga-088272	Otolemur garnettii	97.37	2.00e-165	574.00
IUUC-Oar-089416	Ovis aries	97.70	2.00e-166	577.00
IUUC-Ptr-090944	Pan troglodytes	98.03	2.00e-166	578.00
IUUC-Pan-091861	Papio anubis	98.03	2.00e-166	578.00
IUUC-Psi-093750	Pelodiscus sinensis	93.11	1.00e-160	558.00
IUUC-Pma-094608	Petromyzon marinus	79.35	1.00e-134	472.00
IUUC-Pno-094832	Phaeosphaeria nodorum	32.59	2.00e-26	112.00
IUUC-Ppa-095737	Physcomitrella patens	40.06	1.00e-55	210.00
IUUC-Pfo-096479	Poecilia formosa	86.23	6.00e-144	503.00
IUUC-Pab-098179	Pongo abelii	98.03	2.00e-166	578.00
IUUC-Pop-099532	Populus trichocarpa	40.91	8.00e-56	210.00
IUUC-Pca-100664	Procavia capensis	76.45	2.00e-105	374.00
IUUC-Ppe-102056	Prunus persica	40.26	1.00e-57	216.00
IUUC-Pva-102859	Pteropus vampyrus	98.36	3.00e-166	577.00
IUUC-Pte-104236	Pyrenophora teres	35.56	2.00e-25	109.00
IUUC-Rno-105826	Rattus norvegicus	96.39	6.00e-164	569.00
IUUC-Sha-106660	Sarcophilus harrisii	91.36	4.00e-151	526.00
IUUC-Sja-107800	Schizosaccharomyces japonicus	33.22	5.00e-37	147.00
IUUC-Spo-108244	Schizosaccharomyces pombe	30.92	2.00e-35	142.00
IUUC-Smo-109234	Selaginella moellendorffii	43.68	1.00e-60	226.00
IUUC-Sit-110048	Setaria italica	37.11	1.00e-40	159.00
IUUC-Sly-111618	Solanum lycopersicum	38.78	4.00e-52	198.00
IUUC-Stu-112543	Solanum tuberosum	39.10	2.00e-55	209.00
IUUC-Sar-113743	Sorex araneus	77.70	7.00e-130	456.00
IUUC-Sbi-114309	Sorghum bicolor	38.83	8.00e-42	164.00
IUUC-Ssc-115560	Sus scrofa	92.13	5.00e-153	533.00
IUUC-Tgu-117300	Taeniopygia guttata	92.79	2.00e-160	557.00
IUUC-Tru-117933	Takifugu rubripes	84.92	3.00e-149	520.00
IUUC-Tsy-119574	Tarsius syrichta	87.54	4.00e-143	500.00
IUUC-Tni-120191	Tetraodon nigroviridis	86.92	9.00e-113	399.00
IUUC-Tca-120983	Theobroma cacao	39.81	2.00e-56	212.00
IUUC-Tae-124056	Triticum aestivum	36.36	1.00e-49	190.00
IUUC-Tur-126711	Triticum urartu	36.25	2.00e-48	186.00
IUUC-Tme-127066	Tuber melanosporum	33.83	9.00e-34	137.00
IUUC-Tbe-127802	Tupaia belangeri	98.69	4.00e-167	580.00
IUUC-Ttr-128861	Tursiops truncatus	96.23	1.00e-54	206.00
IUUC-Vda-129720	Verticillium dahliae	29.27	9.00e-23	100.00
IUUC-Vpa-130618	Vicugna pacos	94.33	2.00e-133	467.00
IUUC-Vvi-130981	Vitis vinifera	40.38	3.00e-55	208.00
IUUC-Xtr-132460	Xenopus tropicalis	86.23	7.00e-146	509.00
IUUC-Xma-134154	Xiphophorus maculatus	86.23	4.00e-144	503.00
IUUC-Yli-134554	Yarrowia lipolytica	29.71	4.00e-21	95.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence