iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	47.83	1.10e+00	29.30	IUUC-Sce-106376
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	47.83	1.10e+00	29.30	IUUC-Sce-106376

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Arabidopsis thaliana

Functional Description
(View)

Sugar-1-kinase with a strict substrate specificity for D-glucuronic acid and ATP. Involved in the biosynthesis of UDP-glucuronic acid (UDP-GlcA), providing nucleotide sugars for cell-wall polymers. May be also involved in a salvage pathway for glucuronic acid.

Protein Sequence
(Fasta)

MDMLKKESKK RVREEKMDPN STVSGDGQAT AAIEHRSFAR IGFLGNPSDV YFGRTISLTI 60
GNFWASVKLE PSEHLVIKPH PFHDLVQFTS LDHLLNRLQN EGYYGGVRLL MAICKVFRNY 120

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Nucleotide Sequence
(Fasta)

TGGGACCCAA ATACTGTTAT AAAAAAGGAT CATTAAAATG GATATGTTAA AAAAAGAAAG 60
TAAAAAACGC GTCAGGGAAG AGAAGATGGA TCCGAATTCC ACGGTTTCCG GCGATGGTCA 120

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Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0119--Carbohydrate metabolism
KW-0170--Cobalt
KW-0181--Complete proteome
KW-0418--Kinase
KW-0460--Magnesium
KW-0464--Manganese
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR013750--GHMP_kinase_C_dom
IPR006204--GHMP_kinase_N_dom
IPR006206--Mevalonate/galactokinase
IPR020568--Ribosomal_S5_D2-typ_fold
IPR014721--Ribosomal_S5_D2-typ_fold_subgr

Pfam

PF00288--GHMP_kinases_N

PRINTS

PR00959--MEVGALKINASE

Gene Ontology

GO:0005829--C:cytosol
GO:0005524--F:ATP binding
GO:0047940--F:glucuronokinase activity
GO:0046872--F:metal ion binding
GO:0008266--F:poly(U) RNA binding
GO:0042546--P:cell wall biogenesis
GO:0006020--P:inositol metabolic process
GO:0048868--P:pollen tube development

KEGG

ath:AT3G01640

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ete-032275	Echinops telfairi	37.78	7.30e-01	28.50
IUUC-Gma-043819	Glycine max	30.12	2.20e+00	27.70
IUUC-Pma-094112	Petromyzon marinus	23.13	7.20e+00	26.20
IUUC-Sce-106376	Saccharomyces cerevisiae	47.83	2.30e-01	29.30

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence