iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000075098.5	ENSDART00000136300.3	ENSDARP00000121766.2
ENSDARG00000075098.5	ENSDART00000170546.1	ENSDARP00000139992.1
ENSDARG00000075098.5	ENSDART00000110824.3	ENSDARP00000101619.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.60e-53	175.0	541	578
UBD/Beta-Prp	8.00e-74	249.4	491	675

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlrtgvl 35
           gHt++v+ +++    +++l+sGsdDgt+++WD++++ +
   Q: 541  GHTAKVFHVRWsplREGILCSGSDDGTVRIWDYTQDAC 578
           8**********9987799***************99987 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgk.ilvtgseDrtikvw..dlstgkcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqc 128
           +l++ ++h a+v  +++s++ k +++tg eD++++v+    s+ +++ +++gh+++v  +++sp     l sGs+d t+r+wd  ++ c
   Q: 491  VLHK-YKHPAAVFGCDWSQNNKdMIATGCEDKNVRVYylATSSDQPLKVFTGHTAKVFHVRWSPlREGILCSGSDDGTVRIWDYTQDAC 578
           4444.78999*******988777**************88788999*******************666********************** PP
   S: 129  leetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng.kelvsgsldgtvklwdlq...tg 212
           ++ +lsgh++ v+++ ++ +   ll sGs D t+r+Wd + g++l+t    h  +vy l+ ++++ + ++s+s+d+tv+lw+l    + 
   Q: 579  IN-VLSGHTAPVRGLMWNTEVpYLLTSGSWDYTIRVWDTRDGTCLDTVYD-HGADVYGLTCHPSRpFTMASCSRDSTVRLWSLTpliAP 665
           **.******************9999***********************87.************99899***************988888 PP
   S: 213  ecvrtlnght 222
            +v++l++h+
   Q: 666  LVVNILTDHS 675
           8888888886 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MSQVKQVGLL AAGCQPWNKD VCAASGDRFA YCATLAIYVY QLDHRYNEFK LRAIMSEHKK 60
TITAISWCPH NPEVFASASA DNLLIIWNVA EQKAVARLDN TKGIPASLSW CWNAGDSVAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCGTTTCTC CGTCAGCGGT ACACCTAATC TCAGCACCAG GTCGCTGTCC ACTGACAACG 60
ACAGAGGTAG GTGATCTTCA TTATCTTATT TCCCTCGCAT GTTTCAATCC CGTGTACACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001190	Ailuropoda melanoleuca	81.08	0.00e+00	2226.00
IUUC-Apl-003326	Anas platyrhynchos	83.80	0.00e+00	2248.00
IUUC-Aca-004349	Anolis carolinensis	83.14	0.00e+00	2233.00
IUUC-Ame-011366	Astyanax mexicanus	67.82	0.00e+00	1660.00
IUUC-Bta-013275	Bos taurus	80.69	0.00e+00	2219.00
IUUC-Cja-018970	Callithrix jacchus	80.32	0.00e+00	2202.00
IUUC-Cfa-021237	Canis familiaris	79.91	0.00e+00	2199.00
IUUC-Cpo-021342	Cavia porcellus	74.43	0.00e+00	1436.00
IUUC-Cre-022569	Chlamydomonas reinhardtii	29.36	7.00e-83	302.00
IUUC-Csa-023687	Chlorocebus sabaeus	80.82	0.00e+00	2212.00
IUUC-Cho-024772	Choloepus hoffmanni	72.02	0.00e+00	725.00
IUUC-Csv-026021	Ciona savignyi	41.11	0.00e+00	1034.00
IUUC-Dno-029369	Dasypus novemcinctus	76.56	0.00e+00	2024.00
IUUC-Dor-030645	Dipodomys ordii	77.92	0.00e+00	2121.00
IUUC-Ete-032530	Echinops telfairi	75.79	0.00e+00	2054.00
IUUC-Eca-034405	Equus caballus	81.00	0.00e+00	2220.00
IUUC-Eeu-035006	Erinaceus europaeus	82.86	0.00e+00	1008.00
IUUC-Fca-035965	Felis catus	80.56	0.00e+00	2196.00
IUUC-Fal-037136	Ficedula albicollis	82.40	0.00e+00	2187.00
IUUC-Gmo-039293	Gadus morhua	81.68	0.00e+00	2103.00
IUUC-Gga-040931	Gallus gallus	81.58	0.00e+00	2171.00
IUUC-Gac-042493	Gasterosteus aculeatus	80.86	0.00e+00	2149.00
IUUC-Ggo-045540	Gorilla gorilla	81.19	0.00e+00	2216.00
IUUC-Hsa-046708	Homo sapiens	80.71	0.00e+00	2218.00
IUUC-Lch-050135	Latimeria chalumnae	83.61	0.00e+00	1757.00
IUUC-Loc-051730	Lepisosteus oculatus	88.95	0.00e+00	2393.00
IUUC-Laf-053743	Loxodonta africana	80.93	0.00e+00	2205.00
IUUC-Mcc-055590	Macaca mulatta	80.82	0.00e+00	2210.00
IUUC-Meu-056328	Macropus eugenii	63.59	0.00e+00	1551.00
IUUC-Mga-059877	Meleagris gallopavo	79.52	0.00e+00	2147.00
IUUC-Mmr-060756	Microcebus murinus	81.67	0.00e+00	2231.00
IUUC-Mdo-062749	Monodelphis domestica	81.66	0.00e+00	2246.00
IUUC-Mmu-063668	Mus musculus	77.94	0.00e+00	2156.00
IUUC-Mpu-066856	Mustela putorius furo	81.18	0.00e+00	2206.00
IUUC-Mlu-067186	Myotis lucifugus	77.73	0.00e+00	2135.00
IUUC-Nle-070018	Nomascus leucogenys	80.63	0.00e+00	2219.00
IUUC-Ont-071482	Oreochromis niloticus	76.07	0.00e+00	2017.00
IUUC-Oan-073065	Ornithorhynchus anatinus	83.25	0.00e+00	1749.00
IUUC-Ocu-073786	Oryctolagus cuniculus	80.15	0.00e+00	2189.00
IUUC-Oga-088545	Otolemur garnettii	76.17	0.00e+00	2071.00
IUUC-Oar-090205	Ovis aries	81.26	0.00e+00	2233.00
IUUC-Ptr-091092	Pan troglodytes	80.86	0.00e+00	2219.00
IUUC-Pan-092430	Papio anubis	80.90	0.00e+00	2214.00
IUUC-Psi-093774	Pelodiscus sinensis	85.64	0.00e+00	2303.00
IUUC-Pfo-097414	Poecilia formosa	81.56	0.00e+00	2125.00
IUUC-Pab-097853	Pongo abelii	80.86	0.00e+00	2216.00
IUUC-Pca-100440	Procavia capensis	60.65	6.00e-179	622.00
IUUC-Pva-102838	Pteropus vampyrus	78.79	0.00e+00	2150.00
IUUC-Rno-104951	Rattus norvegicus	76.64	0.00e+00	2103.00
IUUC-Sha-107508	Sarcophilus harrisii	80.08	0.00e+00	2210.00
IUUC-Sar-113549	Sorex araneus	87.30	0.00e+00	1509.00
IUUC-Ssc-115753	Sus scrofa	78.52	0.00e+00	1700.00
IUUC-Tgu-117315	Taeniopygia guttata	83.19	0.00e+00	2242.00
IUUC-Tru-118153	Takifugu rubripes	80.21	0.00e+00	2120.00
IUUC-Tsy-119384	Tarsius syrichta	74.90	0.00e+00	2047.00
IUUC-Tni-120820	Tetraodon nigroviridis	84.26	1.00e-111	395.00
IUUC-Tbe-127579	Tupaia belangeri	66.27	0.00e+00	868.00
IUUC-Ttr-128488	Tursiops truncatus	73.33	0.00e+00	1984.00
IUUC-Vpa-130274	Vicugna pacos	82.33	0.00e+00	982.00
IUUC-Xtr-132199	Xenopus tropicalis	85.48	0.00e+00	2316.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence