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Tag Content
UUCD2 ID IUUC-Cfa-020029
UUCD1 version UUC-CaF-00147
Ensembl Protein ID ENSCAFP00000022867.3
UniProt Accession E2R263; E2R263_CANLF
Genbank Protein ID ENSCAFP00000022867
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAEX03017410
Gene Name TBL1XR1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCAFG00000015543.4 ENSCAFT00000024648.4 ENSCAFP00000022867.3
ENSCAFG00000015543.4 ENSCAFT00000048542.1 ENSCAFP00000038269.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 6.50e-54 177.8 347 385
UBD/Beta-Prp 7.30e-66 222.6 312 513
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHt++v+++++ ++ +ll+s+sdD t+k+W+++++++++
   Q: 347  GHTNEVNAIKWdPTgNLLASCSDDMTLKIWSMKQDNCVH 385
           8***********778*********************987 PP
   

   UBD/Beta-Prp
   S: 14   tcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsf 102
            +v++ ++++ +a+ s+d +i v ++ +   +++++gh++ev+a+k++p+g++l+++s+D+t+k+w++++  cvh l++h+++++++++
   Q: 312  LDVDW-QSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKW 399
           44555.66777777777777777777777777777777777777777777777777777777777777777777777777777777777 PP
   S: 103  sp........sg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtds 182
           sp        +    l+s+s d+t+r+wd++ g c++ tl++h++ v +v+++pdg++l+sGs D++v +W+ +tg l++  +g  t+ 
   Q: 400  SPtgpgtnnpNAnLMLASASFDSTVRLWDVDRGICIH-TLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG--TGG 485
           7755555444222467777777777777777777777.7777777777777777777777777777777777777777777776..777 PP
   S: 183  vyslsfdsngkelvsgsldgtvklwdlq 210
           +  + ++  g  + + + dg+v + dl+
   Q: 486  IFEVCWNAAGDKVGASASDGSVCVLDLR 513
           7777777777777777777777776665 PP
   
Organism Canis familiaris
Protein Sequence
(Fasta)
MSISSDEVNF LVYRYLQESG FSHSAFTFGI ESHISQSNIN GALVPPAALI SIIQKGLQYV 60
EAEVSINEDG TLFDGRPIES LSLIDAVMPD VVQTRQQAYR DKLAQQQAAA AATSTAATNQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cfa-020029|E3,WD_repeat;UBD,Beta-Prp|Canis familiaris
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGTCAGCAGC TGTGACCGGC GGCCCGGACC CCAGCCGCGT CCCCACCTCA ATGCCCGGCC 60
AATGGTAAGC TGCCCACCCG AACGGCGCTC GTCTCCGGTC GCTTTCTCGT CTTGCTGTGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cfa-020029|E3,WD_repeat;UBD,Beta-Prp|Canis familiaris
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08513--LisH
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00667--LisH
SM00320--WD40
Gene Ontology

GO:0000118--C:histone deacetylase complex
GO:0005876--C:spindle microtubule
GO:0017053--C:transcriptional repressor complex
GO:0003714--F:transcription corepressor activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0060613--P:fat pad development
GO:0016575--P:histone deacetylation
GO:0016042--P:lipid catabolic process
GO:0035264--P:multicellular organism growth
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0030814--P:regulation of cAMP metabolic process
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0090207--P:regulation of triglyceride metabolic process
GO:0002021--P:response to dietary excess
GO:0050872--P:white fat cell differentiation
KEGG cfa:488176
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000916 Aegilops tauschii 60.71 5.00e-55 206.00
IUUC-Aml-001717 Ailuropoda melanoleuca 99.81 0.00e+00 957.00
IUUC-Atr-002514 Amborella trichopoda 65.38 4.00e-145 508.00
IUUC-Apl-003708 Anas platyrhynchos 98.58 0.00e+00 924.00
IUUC-Aca-004611 Anolis carolinensis 98.44 0.00e+00 962.00
IUUC-Aly-005622 Arabidopsis lyrata 58.40 1.00e-119 423.00
IUUC-Ath-007137 Arabidopsis thaliana 59.50 3.00e-121 429.00
IUUC-Ago-007869 Ashbya gossypii 28.27 1.00e-32 134.00
IUUC-Ame-011601 Astyanax mexicanus 92.41 0.00e+00 904.00
IUUC-Bta-012418 Bos taurus 99.03 0.00e+00 993.00
IUUC-Bdi-014315 Brachypodium distachyon 60.42 8.00e-135 474.00
IUUC-Bol-016277 Brassica oleracea 57.25 3.00e-127 449.00
IUUC-Bra-016944 Brassica rapa 60.56 1.00e-126 446.00
IUUC-Cja-018832 Callithrix jacchus 99.22 0.00e+00 964.00
IUUC-Cpo-022080 Cavia porcellus 94.17 0.00e+00 924.00
IUUC-Csa-024075 Chlorocebus sabaeus 99.03 0.00e+00 959.00
IUUC-Cho-024872 Choloepus hoffmanni 98.29 2.00e-112 399.00
IUUC-Csv-026257 Ciona savignyi 69.96 0.00e+00 761.00
IUUC-Cme-027258 Cyanidioschyzon merolae 40.55 5.00e-107 381.00
IUUC-Dre-028075 Danio rerio 96.50 0.00e+00 930.00
IUUC-Dno-029196 Dasypus novemcinctus 99.42 0.00e+00 971.00
IUUC-Dor-030732 Dipodomys ordii 99.45 0.00e+00 733.00
IUUC-Eeu-034952 Erinaceus europaeus 89.22 0.00e+00 831.00
IUUC-Fca-035734 Felis catus 99.42 0.00e+00 971.00
IUUC-Fal-037185 Ficedula albicollis 98.83 0.00e+00 964.00
IUUC-Gmo-038870 Gadus morhua 90.66 0.00e+00 931.00
IUUC-Gga-041161 Gallus gallus 98.83 0.00e+00 965.00
IUUC-Gac-041844 Gasterosteus aculeatus 92.23 0.00e+00 955.00
IUUC-Gma-044208 Glycine max 48.34 1.00e-153 536.00
IUUC-Ggo-044882 Gorilla gorilla 99.03 0.00e+00 959.00
IUUC-Hsa-046488 Homo sapiens 99.03 0.00e+00 959.00
IUUC-Itr-047958 Ictidomys tridecemlineatus 100.00 0.00e+00 740.00
IUUC-Kpa-049338 Komagataella pastoris 28.91 8.00e-32 131.00
IUUC-Lch-050672 Latimeria chalumnae 96.12 0.00e+00 974.00
IUUC-Lpe-051084 Leersia perrieri 62.64 2.00e-136 479.00
IUUC-Loc-052030 Lepisosteus oculatus 95.75 0.00e+00 963.00
IUUC-Laf-054280 Loxodonta africana 98.64 0.00e+00 992.00
IUUC-Mcc-055203 Macaca mulatta 99.03 0.00e+00 959.00
IUUC-Meu-056563 Macropus eugenii 98.32 6.00e-135 473.00
IUUC-Mtr-058624 Medicago truncatula 60.44 9.00e-129 453.00
IUUC-Mga-059660 Meleagris gallopavo 98.83 0.00e+00 965.00
IUUC-Mvi-060557 Microbotryum violaceum 36.77 2.00e-70 260.00
IUUC-Mmr-060925 Microcebus murinus 98.20 0.00e+00 924.00
IUUC-Mdo-062078 Monodelphis domestica 98.64 0.00e+00 962.00
IUUC-Mmu-063603 Mus musculus 98.83 0.00e+00 967.00
IUUC-Mac-065508 Musa acuminata 61.80 2.00e-93 335.00
IUUC-Mpu-066741 Mustela putorius furo 100.00 0.00e+00 959.00
IUUC-Mlu-068152 Myotis lucifugus 99.22 0.00e+00 964.00
IUUC-Nle-069229 Nomascus leucogenys 99.03 0.00e+00 959.00
IUUC-Opr-070277 Ochotona princeps 88.36 0.00e+00 820.00
IUUC-Ont-072623 Oreochromis niloticus 92.23 0.00e+00 955.00
IUUC-Ocu-074280 Oryctolagus cuniculus 97.32 0.00e+00 960.00
IUUC-Oba-075618 Oryza barthii 48.65 2.00e-144 506.00
IUUC-Obr-076718 Oryza brachyantha 62.91 5.00e-137 481.00
IUUC-Ogl-077302 Oryza glaberrima 50.81 7.00e-157 547.00
IUUC-Ogu-078718 Oryza glumaepatula 50.81 7.00e-157 547.00
IUUC-Oin-079515 Oryza indica 44.12 2.00e-94 340.00
IUUC-Olo-080427 Oryza longistaminata 63.32 4.00e-132 465.00
IUUC-Ome-081696 Oryza meridionalis 49.73 2.00e-151 529.00
IUUC-Oni-082137 Oryza nivara 50.81 7.00e-157 547.00
IUUC-Opu-083505 Oryza punctata 48.65 2.00e-143 502.00
IUUC-Oru-085276 Oryza rufipogon 50.63 2.00e-156 545.00
IUUC-Osa-085791 Oryza sativa 50.81 7.00e-157 547.00
IUUC-Ola-087365 Oryzias latipes 95.34 0.00e+00 954.00
IUUC-Olu-087589 Ostreococcus lucimarinus 52.25 2.00e-155 542.00
IUUC-Oga-088357 Otolemur garnettii 95.33 0.00e+00 906.00
IUUC-Oar-089214 Ovis aries 99.22 0.00e+00 996.00
IUUC-Ptr-091532 Pan troglodytes 99.03 0.00e+00 959.00
IUUC-Pan-091927 Papio anubis 99.03 0.00e+00 959.00
IUUC-Psi-093941 Pelodiscus sinensis 92.03 0.00e+00 942.00
IUUC-Pma-094105 Petromyzon marinus 63.28 2.00e-100 358.00
IUUC-Ppa-095868 Physcomitrella patens 65.16 9.00e-140 490.00
IUUC-Pfo-096158 Poecilia formosa 92.23 0.00e+00 955.00
IUUC-Pab-098705 Pongo abelii 99.03 0.00e+00 959.00
IUUC-Pca-100256 Procavia capensis 98.43 0.00e+00 949.00
IUUC-Ppe-101572 Prunus persica 63.69 5.00e-128 451.00
IUUC-Pva-102616 Pteropus vampyrus 98.82 0.00e+00 951.00
IUUC-Rno-105411 Rattus norvegicus 99.03 0.00e+00 969.00
IUUC-Sce-106132 Saccharomyces cerevisiae 25.13 7.00e-43 168.00
IUUC-Sha-106636 Sarcophilus harrisii 97.86 0.00e+00 956.00
IUUC-Smo-109301 Selaginella moellendorffii 63.49 8.00e-143 500.00
IUUC-Sit-110710 Setaria italica 63.71 1.00e-142 499.00
IUUC-Sly-111042 Solanum lycopersicum 50.68 2.00e-150 525.00
IUUC-Stu-112744 Solanum tuberosum 49.51 1.00e-142 499.00
IUUC-Sar-112971 Sorex araneus 90.20 0.00e+00 867.00
IUUC-Sbi-114420 Sorghum bicolor 63.19 2.00e-142 499.00
IUUC-Sre-115175 Sporisorium reilianum 37.17 5.00e-58 219.00
IUUC-Ssc-115695 Sus scrofa 97.47 0.00e+00 949.00
IUUC-Tgu-117009 Taeniopygia guttata 98.81 0.00e+00 948.00
IUUC-Tru-118581 Takifugu rubripes 94.95 0.00e+00 958.00
IUUC-Tsy-119424 Tarsius syrichta 81.85 0.00e+00 738.00
IUUC-Tni-119986 Tetraodon nigroviridis 95.34 0.00e+00 960.00
IUUC-Tca-121739 Theobroma cacao 56.87 5.00e-125 441.00
IUUC-Tme-127126 Tuber melanosporum 38.42 2.00e-58 219.00
IUUC-Tbe-127665 Tupaia belangeri 82.85 0.00e+00 826.00
IUUC-Vpa-130768 Vicugna pacos 98.62 0.00e+00 944.00
IUUC-Vvi-131193 Vitis vinifera 60.16 1.00e-128 453.00
IUUC-Xtr-132842 Xenopus tropicalis 92.00 0.00e+00 911.00
IUUC-Xma-134020 Xiphophorus maculatus 92.23 0.00e+00 956.00
Created Date 25-Jun-2017

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