iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-072954

Ensembl Protein ID

ENSOANP00000010247.1

UniProt Accession

F6WHU8; F6WHU8_ORNAN

Protein Name

Uncharacterized protein

Gene Name

BRWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000006422.3	ENSOANT00000010249.1	ENSOANP00000010247.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.00e-33	113.2	367	397
UBD/Beta-Prp	1.30e-52	179.1	328	542

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           Htd+v +++f ++ ++++sGs+Dgt ++W++
   Q: 367  HTDKVDSIQFsNTgDRFLSGSRDGTARIWRF 397
           **********9778***************96 PP

UBD/Beta-Prp

   S: 56   tavkfspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee........... 131
            + +fs  g +l+tgs+D++i+ +   ++t++ +  l+ h+d+v s++fs +gd+++sGs+d t+r+w  e+ ++ +            
   Q: 328  LCSSFSVGGMFLATGSTDHVIRMYffGFETPEKIAELESHTDKVDSIQFSNTGDRFLSGSRDGTARIWRFEQPEWRSIlldmatrlsdd 416
           4667888888*************999999***************************************9999999988999*****999 PP
   S: 132  ...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgec 214
               ++  +  v++++++++++l+v++ +D  +++W++ tg+ll+ l g h d v  l+   fds  + ++s+++dg + +wd+ +g+ 
   Q: 417  qseEEKFMKPKVTMIAWNQNDSLVVTAVNDHLLKVWNSHTGQLLHNLVG-HADEVFVLEthpFDS--RIMLSAGHDGNIFIWDITKGTR 502
           9887777777899******99**************************99.********9555555..999**************97766 PP
   S: 215  ......vrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
                 + + +gh   v + +fs+++++++++ s+g + i+
   Q: 503  tkhyfnMIEGQGH-GAVFDCKFSSDGQHFACTDSHGHLLIF 542
           3344433344444.556667888899999999999988876 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MAEPSLARRS VPLIESELYF LIARFLSAGP CRRATQALVQ ELEQYQLLPK RLDWEGNEHD 60
RSYEELVLSN KHVAPDHLLQ ICQRIGPILD KEIPPSILKV TSLLGAGRQS LLRTAKDCRN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGAAC CTTCGCTCGC CCGCCGTTCC GTGCCGCTCA TCGAATCAGG TAAGAAGGAG 60
GAGGAGGAGG CAGGGACAGT CCTTCTCCTT CCGCCCCGGG GGTGCCCCCT TCCTCACCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001113	Aegilops tauschii	30.58	1.00e-62	235.00
IUUC-Aml-002332	Ailuropoda melanoleuca	77.06	0.00e+00	2598.00
IUUC-Apl-004083	Anas platyrhynchos	63.57	0.00e+00	2202.00
IUUC-Aca-004348	Anolis carolinensis	74.51	0.00e+00	1991.00
IUUC-Aly-006517	Arabidopsis lyrata	30.53	5.00e-73	269.00
IUUC-Ath-006577	Arabidopsis thaliana	30.38	3.00e-72	266.00
IUUC-Ame-010718	Astyanax mexicanus	70.91	0.00e+00	1180.00
IUUC-Bta-013217	Bos taurus	71.57	0.00e+00	2895.00
IUUC-Bdi-014797	Brachypodium distachyon	29.88	5.00e-59	223.00
IUUC-Bol-015737	Brassica oleracea	30.14	2.00e-73	271.00
IUUC-Bra-017961	Brassica rapa	30.10	9.00e-73	268.00
IUUC-Cja-019966	Callithrix jacchus	84.36	0.00e+00	2511.00
IUUC-Cfa-021037	Canis familiaris	70.48	0.00e+00	2824.00
IUUC-Cpo-021934	Cavia porcellus	82.98	0.00e+00	2511.00
IUUC-Cre-023003	Chlamydomonas reinhardtii	34.57	3.00e-34	140.00
IUUC-Csa-023352	Chlorocebus sabaeus	84.52	0.00e+00	2290.00
IUUC-Cho-024690	Choloepus hoffmanni	79.05	0.00e+00	853.00
IUUC-Cin-025553	Ciona intestinalis	39.11	3.00e-110	392.00
IUUC-Csv-025813	Ciona savignyi	44.39	0.00e+00	642.00
IUUC-Dre-028508	Danio rerio	58.79	0.00e+00	1656.00
IUUC-Dno-028938	Dasypus novemcinctus	68.94	0.00e+00	2788.00
IUUC-Dme-031752	Drosophila melanogaster	49.59	0.00e+00	664.00
IUUC-Ete-032650	Echinops telfairi	59.53	0.00e+00	1291.00
IUUC-Eca-034349	Equus caballus	79.88	0.00e+00	2526.00
IUUC-Fca-035485	Felis catus	73.71	0.00e+00	2625.00
IUUC-Fal-037307	Ficedula albicollis	72.72	0.00e+00	2483.00
IUUC-Gga-041097	Gallus gallus	63.88	0.00e+00	1843.00
IUUC-Gac-042435	Gasterosteus aculeatus	56.59	0.00e+00	1595.00
IUUC-Gma-044324	Glycine max	29.77	3.00e-69	257.00
IUUC-Ggo-045500	Gorilla gorilla	71.00	0.00e+00	2827.00
IUUC-Hsa-046350	Homo sapiens	70.39	0.00e+00	2864.00
IUUC-Itr-047962	Ictidomys tridecemlineatus	83.76	0.00e+00	1044.00
IUUC-Lch-049662	Latimeria chalumnae	80.05	0.00e+00	1357.00
IUUC-Lpe-051619	Leersia perrieri	30.71	1.00e-69	258.00
IUUC-Loc-052853	Lepisosteus oculatus	66.57	0.00e+00	1868.00
IUUC-Laf-053848	Loxodonta africana	83.03	0.00e+00	2475.00
IUUC-Mcc-054638	Macaca mulatta	70.36	0.00e+00	2853.00
IUUC-Meu-056739	Macropus eugenii	80.35	0.00e+00	1120.00
IUUC-Mtr-058094	Medicago truncatula	31.19	6.00e-72	266.00
IUUC-Mga-060063	Meleagris gallopavo	63.81	0.00e+00	1791.00
IUUC-Mmr-061227	Microcebus murinus	71.24	0.00e+00	2873.00
IUUC-Mdo-062074	Monodelphis domestica	70.30	0.00e+00	2783.00
IUUC-Mmu-064075	Mus musculus	71.86	0.00e+00	2613.00
IUUC-Mac-065343	Musa acuminata	31.44	1.00e-77	285.00
IUUC-Mpu-066643	Mustela putorius furo	85.69	0.00e+00	2388.00
IUUC-Mlu-067735	Myotis lucifugus	69.80	0.00e+00	2727.00
IUUC-Nle-069402	Nomascus leucogenys	85.10	0.00e+00	2485.00
IUUC-Ont-071589	Oreochromis niloticus	58.22	0.00e+00	1567.00
IUUC-Ocu-074456	Oryctolagus cuniculus	69.67	0.00e+00	2789.00
IUUC-Oba-075709	Oryza barthii	29.30	8.00e-61	229.00
IUUC-Obr-076619	Oryza brachyantha	30.29	1.00e-69	258.00
IUUC-Opu-083233	Oryza punctata	30.14	7.00e-65	242.00
IUUC-Oru-085195	Oryza rufipogon	29.30	9.00e-61	228.00
IUUC-Ola-086648	Oryzias latipes	57.83	0.00e+00	1637.00
IUUC-Olu-087745	Ostreococcus lucimarinus	26.09	1.00e-54	208.00
IUUC-Oga-087938	Otolemur garnettii	65.29	0.00e+00	2478.00
IUUC-Oar-090214	Ovis aries	70.90	0.00e+00	2763.00
IUUC-Ptr-091213	Pan troglodytes	71.02	0.00e+00	2839.00
IUUC-Pan-092444	Papio anubis	85.09	0.00e+00	2524.00
IUUC-Psi-093271	Pelodiscus sinensis	69.41	0.00e+00	2283.00
IUUC-Pma-094427	Petromyzon marinus	63.66	6.00e-128	449.00
IUUC-Ppa-095793	Physcomitrella patens	29.27	2.00e-73	271.00
IUUC-Pfo-097318	Poecilia formosa	62.71	0.00e+00	1792.00
IUUC-Pab-097573	Pongo abelii	83.57	0.00e+00	2422.00
IUUC-Pop-099672	Populus trichocarpa	30.94	8.00e-74	272.00
IUUC-Pca-100759	Procavia capensis	64.60	0.00e+00	1055.00
IUUC-Ppe-101849	Prunus persica	30.88	5.00e-74	273.00
IUUC-Pva-102782	Pteropus vampyrus	69.96	0.00e+00	2759.00
IUUC-Rno-105687	Rattus norvegicus	66.75	0.00e+00	2695.00
IUUC-Sha-106680	Sarcophilus harrisii	71.90	0.00e+00	2831.00
IUUC-Sly-111348	Solanum lycopersicum	30.47	3.00e-74	273.00
IUUC-Sar-113519	Sorex araneus	72.17	0.00e+00	1587.00
IUUC-Sbi-114195	Sorghum bicolor	28.25	1.00e-59	223.00
IUUC-Tgu-116513	Taeniopygia guttata	65.91	0.00e+00	2516.00
IUUC-Tru-118186	Takifugu rubripes	59.09	0.00e+00	945.00
IUUC-Tsy-118921	Tarsius syrichta	80.64	0.00e+00	1848.00
IUUC-Tni-120110	Tetraodon nigroviridis	56.31	0.00e+00	1536.00
IUUC-Tca-121615	Theobroma cacao	30.59	7.00e-69	256.00
IUUC-Tae-125478	Triticum aestivum	30.64	1.00e-71	265.00
IUUC-Tur-126809	Triticum urartu	30.47	4.00e-69	256.00
IUUC-Tbe-127663	Tupaia belangeri	77.66	0.00e+00	1126.00
IUUC-Ttr-128561	Tursiops truncatus	69.04	0.00e+00	2683.00
IUUC-Vpa-130444	Vicugna pacos	67.98	0.00e+00	2551.00
IUUC-Vvi-131362	Vitis vinifera	30.48	6.00e-75	276.00
IUUC-Xma-134159	Xiphophorus maculatus	57.18	0.00e+00	1515.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence