iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000011424.1	ENSPPYT00000013263.1	ENSPPYP00000012751.1
ENSPPYG00000011424.1	ENSPPYT00000013264.1	ENSPPYP00000012752.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.40e-35	119.1	166	203
UBD/Beta-Prp	9.00e-55	186.0	268	525

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH + v+c+af  + +++ +GsdD+ +k+W+++ g+ll
   Q: 166  GHLSAVYCVAFdRTgHRIFTGSDDCLVKIWSTHNGRLL 203
           8**********955599***************999987 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvttgkl......lrslsgheaevtavk..fspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlsl 100
           +++++++++dgt+  w+++ ++l      l+  ++  ++v+ ++  fs  g +l+tgs+D++i+ +   +++++ +  l+ h+d+v s+
   Q: 268  QRYMVSTGADGTVCFWQWDLESLkfsprpLKFTEKPRPGVQMLCssFSVGGMFLATGSTDHVIRMYflGFEAPEKIAELESHTDKVDSI 356
           689*****************99999988777778888888755522888888**************99999****************** PP
   S: 101  sfspsgdklvsGshdrtirvwdletgqclee...............tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           +f+ +gd+++sGs+d t+r+w  e+ ++ +                 ++  +  v++++++++++++v++ +D ++++W++ tg+ll+ 
   Q: 357  QFCNNGDRFLSGSRDGTARIWRFEQLEWRSIlldmatrisgdlsseEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHN 445
           **************************99998999********998877777888*********************************** PP
   S: 175  ltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriW 249
           l g h d v  l+   fds  + ++s+++dg++ +wd+ +g+ ++ + +         v + +fs+++++++++ s+g + i+
   Q: 446  LMG-HADEVFVLEthpFDS--RIMLSAGHDGSIFIWDITKGTKMKHYFNMIegqghGAVFDCKFSQDGQHFACTDSHGHLLIF 525
           **9.*********555555..99****************999977766544444456677789999*****999999998886 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

LYFLIARYLS APCRRAAQVL VQELEQYQLL PKRLDWEGNE HNRSYEELVL SNKHVAPDHL 60
LQICQRIGPM LDKEIPPSIS RVTSLLGAGR QSLLRTAKDC RHTVWKGSAF AALHRGRPPE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGTACTTCC TCATCGCCCG GTACCTATCG GCGGCCGTGT CGGAGAGCGG CCCAGGTGAG 60
TGCGGGCCCG CGGGCGGCTG CGGACTTGGC GTCTCCAGTG TCCCCGCCGC CGCCGGGGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002332	Ailuropoda melanoleuca	83.34	0.00e+00	3236.00
IUUC-Apl-004083	Anas platyrhynchos	68.01	0.00e+00	1899.00
IUUC-Aca-004348	Anolis carolinensis	71.11	0.00e+00	1899.00
IUUC-Ame-010718	Astyanax mexicanus	70.61	0.00e+00	1167.00
IUUC-Bta-013217	Bos taurus	87.46	0.00e+00	3588.00
IUUC-Cja-019966	Callithrix jacchus	93.86	0.00e+00	3919.00
IUUC-Cfa-021037	Canis familiaris	87.69	0.00e+00	3512.00
IUUC-Cpo-021934	Cavia porcellus	90.51	0.00e+00	2686.00
IUUC-Csa-023352	Chlorocebus sabaeus	96.24	0.00e+00	3766.00
IUUC-Cho-024690	Choloepus hoffmanni	77.82	0.00e+00	1298.00
IUUC-Dre-028205	Danio rerio	68.15	0.00e+00	1139.00
IUUC-Dno-028938	Dasypus novemcinctus	84.89	0.00e+00	3480.00
IUUC-Eca-034349	Equus caballus	88.38	0.00e+00	3470.00
IUUC-Fca-035485	Felis catus	81.60	0.00e+00	3023.00
IUUC-Fal-037307	Ficedula albicollis	76.24	0.00e+00	2224.00
IUUC-Gga-040865	Gallus gallus	75.94	0.00e+00	2242.00
IUUC-Gma-043340	Glycine max	30.12	3.00e-68	254.00
IUUC-Ggo-045500	Gorilla gorilla	97.61	0.00e+00	4038.00
IUUC-Hsa-046350	Homo sapiens	97.61	0.00e+00	4039.00
IUUC-Itr-047962	Ictidomys tridecemlineatus	90.94	0.00e+00	1097.00
IUUC-Lch-049662	Latimeria chalumnae	65.83	0.00e+00	2024.00
IUUC-Laf-053848	Loxodonta africana	86.36	0.00e+00	3474.00
IUUC-Mcc-054638	Macaca mulatta	96.48	0.00e+00	3992.00
IUUC-Meu-056739	Macropus eugenii	79.91	0.00e+00	1118.00
IUUC-Mga-060165	Meleagris gallopavo	76.18	0.00e+00	2224.00
IUUC-Mmr-061227	Microcebus murinus	90.94	0.00e+00	3723.00
IUUC-Mdo-062074	Monodelphis domestica	81.88	0.00e+00	2375.00
IUUC-Mmu-064075	Mus musculus	82.06	0.00e+00	2919.00
IUUC-Mpu-066643	Mustela putorius furo	89.04	0.00e+00	2930.00
IUUC-Mlu-067735	Myotis lucifugus	85.38	0.00e+00	3419.00
IUUC-Nle-069402	Nomascus leucogenys	94.81	0.00e+00	3062.00
IUUC-Ont-072298	Oreochromis niloticus	60.84	0.00e+00	1792.00
IUUC-Oan-072954	Ornithorhynchus anatinus	83.31	0.00e+00	2436.00
IUUC-Ocu-074456	Oryctolagus cuniculus	87.15	0.00e+00	3614.00
IUUC-Oba-075709	Oryza barthii	29.93	3.00e-58	221.00
IUUC-Oru-085195	Oryza rufipogon	29.93	3.00e-58	221.00
IUUC-Olu-087745	Ostreococcus lucimarinus	26.67	7.00e-57	216.00
IUUC-Oga-087938	Otolemur garnettii	81.49	0.00e+00	3152.00
IUUC-Oar-090214	Ovis aries	86.54	0.00e+00	3476.00
IUUC-Ptr-091213	Pan troglodytes	97.66	0.00e+00	4009.00
IUUC-Pan-092444	Papio anubis	95.75	0.00e+00	3966.00
IUUC-Psi-093271	Pelodiscus sinensis	75.49	0.00e+00	1994.00
IUUC-Pma-094427	Petromyzon marinus	67.30	1.00e-129	455.00
IUUC-Ppa-095793	Physcomitrella patens	29.90	1.00e-71	266.00
IUUC-Pfo-097318	Poecilia formosa	61.50	0.00e+00	1738.00
IUUC-Pca-100759	Procavia capensis	70.37	0.00e+00	1123.00
IUUC-Pva-102782	Pteropus vampyrus	86.93	0.00e+00	3512.00
IUUC-Rno-105687	Rattus norvegicus	78.07	0.00e+00	3196.00
IUUC-Sar-113519	Sorex araneus	80.71	0.00e+00	1788.00
IUUC-Tgu-116513	Taeniopygia guttata	76.11	0.00e+00	2240.00
IUUC-Tsy-118921	Tarsius syrichta	89.92	0.00e+00	2037.00
IUUC-Tca-121098	Theobroma cacao	30.70	7.00e-77	283.00
IUUC-Tbe-127663	Tupaia belangeri	78.07	0.00e+00	1276.00
IUUC-Ttr-128561	Tursiops truncatus	85.72	0.00e+00	3347.00
IUUC-Vpa-130444	Vicugna pacos	84.79	0.00e+00	3271.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence