iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-068038

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02024192

Gene Name

AMBRA1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000009880.2	ENSMLUT00000009886.2	ENSMLUP00000009013.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.90e-08	32.4	93	126

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd..tllvsGsdDgtikvWDlr 31
           gH    +c+ f ++  +l++sG+ Dg +++WDl+
   Q: 93   GHRRTPWCVTFhPTisGLIASGCLDGEVRIWDLH 126
           6777779*****76779***************97 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MKVVPEKNAV RILWGRERGT RAFGAQRLLQ ELVEDKTRWM KWEGKRVELP DSPRSTFLLA 60
FSPDRTLLAS THVNHNIYIT EVKTGKCVHS LIGHRRTPWC VTFHPTISGL IASGCLDGEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGGTTG TTCCAGAGAA AAATGCTGTC CGCATACTCT GGGGGCGAGA ACGGGGCACT 60
CGGGCCTTTG GAGCTCAGCG GCTTCTGCAG GAGCTGGTGG AAGATAAAAC CCGGTGGATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005930--C:axoneme
GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0045335--C:phagocytic vesicle
GO:0006914--P:autophagy
GO:0008285--P:negative regulation of cell proliferation
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0021915--P:neural tube development
GO:0098779--P:positive regulation of macromitophagy in response to mitochondrial depolarization
GO:0043552--P:positive regulation of phosphatidylinositol 3-kinase activity
GO:2000785--P:regulation of autophagosome assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001917	Ailuropoda melanoleuca	96.81	0.00e+00	1780.00
IUUC-Atr-002557	Amborella trichopoda	37.74	6.00e-30	126.00
IUUC-Apl-004186	Anas platyrhynchos	81.53	0.00e+00	1924.00
IUUC-Aca-004419	Anolis carolinensis	77.10	0.00e+00	1808.00
IUUC-Aly-006308	Arabidopsis lyrata	37.85	1.00e-28	121.00
IUUC-Ath-007656	Arabidopsis thaliana	37.09	3.00e-28	120.00
IUUC-Ame-011354	Astyanax mexicanus	58.85	0.00e+00	1298.00
IUUC-Bta-012455	Bos taurus	93.76	0.00e+00	2203.00
IUUC-Bdi-014580	Brachypodium distachyon	42.33	4.00e-30	126.00
IUUC-Bol-016094	Brassica oleracea	40.22	1.00e-28	122.00
IUUC-Bra-017308	Brassica rapa	40.76	1.00e-29	125.00
IUUC-Cja-019073	Callithrix jacchus	95.87	3.00e-159	555.00
IUUC-Cfa-020994	Canis familiaris	92.93	0.00e+00	1498.00
IUUC-Cpo-022101	Cavia porcellus	94.31	0.00e+00	2168.00
IUUC-Csa-023273	Chlorocebus sabaeus	93.85	0.00e+00	1581.00
IUUC-Cin-025567	Ciona intestinalis	52.20	3.00e-56	213.00
IUUC-Csv-026005	Ciona savignyi	51.26	3.00e-56	211.00
IUUC-Dre-028282	Danio rerio	58.72	0.00e+00	1274.00
IUUC-Dno-029948	Dasypus novemcinctus	94.62	0.00e+00	2204.00
IUUC-Dor-030568	Dipodomys ordii	96.08	0.00e+00	1234.00
IUUC-Ete-032864	Echinops telfairi	93.47	0.00e+00	1155.00
IUUC-Eca-034392	Equus caballus	94.47	0.00e+00	1611.00
IUUC-Eeu-034440	Erinaceus europaeus	87.02	0.00e+00	1220.00
IUUC-Fca-035359	Felis catus	93.49	0.00e+00	2164.00
IUUC-Fal-037483	Ficedula albicollis	81.89	0.00e+00	1964.00
IUUC-Gmo-039343	Gadus morhua	75.18	0.00e+00	769.00
IUUC-Gga-040787	Gallus gallus	82.67	0.00e+00	1233.00
IUUC-Gac-041321	Gasterosteus aculeatus	61.58	0.00e+00	1354.00
IUUC-Gma-044022	Glycine max	36.63	4.00e-29	123.00
IUUC-Ggo-044775	Gorilla gorilla	92.64	0.00e+00	1062.00
IUUC-Hsa-045708	Homo sapiens	95.23	0.00e+00	2253.00
IUUC-Hvu-047536	Hordeum vulgare	41.57	2.00e-29	124.00
IUUC-Itr-048376	Ictidomys tridecemlineatus	96.53	0.00e+00	1232.00
IUUC-Lch-050255	Latimeria chalumnae	69.46	0.00e+00	1414.00
IUUC-Lpe-050684	Leersia perrieri	41.76	2.00e-30	127.00
IUUC-Loc-052881	Lepisosteus oculatus	67.39	0.00e+00	1493.00
IUUC-Laf-053342	Loxodonta africana	72.59	0.00e+00	954.00
IUUC-Mcc-055848	Macaca mulatta	93.08	0.00e+00	2226.00
IUUC-Meu-056320	Macropus eugenii	84.75	0.00e+00	1079.00
IUUC-Mtr-058685	Medicago truncatula	39.68	2.00e-29	124.00
IUUC-Mga-059401	Meleagris gallopavo	85.63	0.00e+00	1665.00
IUUC-Mmr-061037	Microcebus murinus	94.63	0.00e+00	2197.00
IUUC-Mdo-062484	Monodelphis domestica	74.45	0.00e+00	1679.00
IUUC-Mmu-064090	Mus musculus	94.08	0.00e+00	2206.00
IUUC-Mac-065675	Musa acuminata	37.20	2.00e-29	124.00
IUUC-Mpu-066165	Mustela putorius furo	93.22	0.00e+00	1509.00
IUUC-Nle-069361	Nomascus leucogenys	97.32	0.00e+00	1930.00
IUUC-Opr-070360	Ochotona princeps	92.69	0.00e+00	882.00
IUUC-Ont-071277	Oreochromis niloticus	63.12	0.00e+00	1363.00
IUUC-Oan-073623	Ornithorhynchus anatinus	82.50	0.00e+00	1019.00
IUUC-Ocu-074600	Oryctolagus cuniculus	95.75	0.00e+00	1384.00
IUUC-Oba-075024	Oryza barthii	34.30	5.00e-32	133.00
IUUC-Obr-076172	Oryza brachyantha	34.71	6.00e-33	136.00
IUUC-Ogl-077411	Oryza glaberrima	34.30	6.00e-32	132.00
IUUC-Ogu-078025	Oryza glumaepatula	38.19	8.00e-32	132.00
IUUC-Oni-082463	Oryza nivara	34.30	5.00e-32	133.00
IUUC-Opu-084041	Oryza punctata	38.19	1.00e-31	131.00
IUUC-Oru-085075	Oryza rufipogon	38.19	2.00e-31	131.00
IUUC-Osa-085781	Oryza sativa	34.30	6.00e-32	132.00
IUUC-Ola-086729	Oryzias latipes	63.09	0.00e+00	1386.00
IUUC-Olu-087735	Ostreococcus lucimarinus	40.32	7.00e-24	105.00
IUUC-Oga-089113	Otolemur garnettii	93.56	0.00e+00	2145.00
IUUC-Oar-090171	Ovis aries	95.13	0.00e+00	2047.00
IUUC-Ptr-090970	Pan troglodytes	95.31	0.00e+00	2254.00
IUUC-Pan-092778	Papio anubis	93.74	0.00e+00	1599.00
IUUC-Psi-093571	Pelodiscus sinensis	81.36	0.00e+00	1953.00
IUUC-Pma-094563	Petromyzon marinus	73.75	2.00e-105	374.00
IUUC-Ppa-095832	Physcomitrella patens	36.70	3.00e-30	127.00
IUUC-Pfo-097365	Poecilia formosa	60.61	0.00e+00	1265.00
IUUC-Pab-098647	Pongo abelii	96.81	0.00e+00	1232.00
IUUC-Pop-099742	Populus trichocarpa	40.32	2.00e-29	124.00
IUUC-Pca-101035	Procavia capensis	92.08	0.00e+00	1172.00
IUUC-Ppe-101411	Prunus persica	37.56	3.00e-29	124.00
IUUC-Pva-103187	Pteropus vampyrus	98.81	0.00e+00	944.00
IUUC-Rno-105701	Rattus norvegicus	93.47	0.00e+00	2186.00
IUUC-Sha-107612	Sarcophilus harrisii	84.19	0.00e+00	1977.00
IUUC-Smo-108871	Selaginella moellendorffii	39.08	7.00e-27	115.00
IUUC-Sit-110786	Setaria italica	38.12	2.00e-32	134.00
IUUC-Sly-110859	Solanum lycopersicum	38.10	5.00e-32	132.00
IUUC-Stu-112031	Solanum tuberosum	38.57	4.00e-32	133.00
IUUC-Sar-113242	Sorex araneus	94.37	0.00e+00	1063.00
IUUC-Ssc-116094	Sus scrofa	95.15	0.00e+00	2254.00
IUUC-Tru-118308	Takifugu rubripes	61.81	0.00e+00	1318.00
IUUC-Tsy-119552	Tarsius syrichta	93.61	0.00e+00	1215.00
IUUC-Tca-121616	Theobroma cacao	37.80	5.00e-31	129.00
IUUC-Tae-124768	Triticum aestivum	42.17	5.00e-30	125.00
IUUC-Tur-126480	Triticum urartu	42.17	2.00e-30	127.00
IUUC-Tbe-127902	Tupaia belangeri	94.38	0.00e+00	973.00
IUUC-Ttr-129278	Tursiops truncatus	93.89	0.00e+00	1182.00
IUUC-Vpa-130741	Vicugna pacos	87.50	0.00e+00	845.00
IUUC-Vvi-131437	Vitis vinifera	45.45	5.00e-29	123.00
IUUC-Xtr-132247	Xenopus tropicalis	64.47	0.00e+00	1324.00
IUUC-Xma-134277	Xiphophorus maculatus	62.02	0.00e+00	1382.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence