iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004733

Ensembl Protein ID

ENSACAP00000001102.2

UniProt Accession

H9G4S4; H9G4S4_ANOCA

Protein Name

Protein HIRA

Gene Name

HIRA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000001056.3	ENSACAT00000001134.3	ENSACAP00000001102.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.30e-20	70.4	69	98

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H + v+c+++ ++  +l+sG+dD+ i+vW 
   Q: 69   HLACVNCVRWsNNgLYLASGGDDKLIMVWK 98
           8899******977799*************7 PP

Organism

Anolis carolinensis

Functional Description
(View)

Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

Protein Sequence
(Fasta)

MKLLKPAWVN HNGKPIFSVD IHPDGTKFAT GGQGEDSGKV VIWNMAPVVR EEDEKNENVP 60
KMLCQMDNHL ACVNCVRWSN NGLYLASGGD DKLIMVWKRA AYIGPSTVFG SSSKLANVEQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGCTCC TGAAGCCCGC CTGGGTCAAC CACAACGGTG AGCGCTCTGA GCATGGGCAG 60
AGTGCATTGG CGACGGGAGG GAGGGAGGAA GGAAGGGGCC TGCTTTTTGG TGCTACTCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR031120--HIR1
IPR011494--Hira
IPR019015--HIRA_B_motif
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07569--Hira
PF09453--HIRA_B
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0000790--C:nuclear chromatin
GO:0043234--C:protein complex
GO:0031491--F:nucleosome binding
GO:0003714--F:transcription corepressor activity
GO:0016569--P:covalent chromatin modification
GO:0006336--P:DNA replication-independent nucleosome assembly
GO:0007369--P:gastrulation
GO:0042692--P:muscle cell differentiation
GO:0001649--P:osteoblast differentiation
GO:0031935--P:regulation of chromatin silencing
GO:0006351--P:transcription, DNA-templated

KEGG

acs:100556463

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001039	Aegilops tauschii	35.46	1.00e-88	321.00
IUUC-Aml-001723	Ailuropoda melanoleuca	82.61	0.00e+00	1563.00
IUUC-Atr-003132	Amborella trichopoda	36.36	2.00e-89	323.00
IUUC-Apl-003197	Anas platyrhynchos	87.63	0.00e+00	1704.00
IUUC-Aly-005446	Arabidopsis lyrata	35.06	9.00e-83	301.00
IUUC-Ath-007627	Arabidopsis thaliana	29.07	2.00e-100	360.00
IUUC-Ago-007766	Ashbya gossypii	28.63	5.00e-59	222.00
IUUC-Acl-008104	Aspergillus clavatus	30.80	2.00e-65	244.00
IUUC-Afl-008591	Aspergillus flavus	32.21	6.00e-64	239.00
IUUC-Afu-008781	Aspergillus fumigatus	31.98	1.00e-59	225.00
IUUC-Ani-009272	Aspergillus nidulans	29.30	7.00e-56	212.00
IUUC-Ang-009655	Aspergillus niger	31.91	6.00e-65	242.00
IUUC-Aor-010119	Aspergillus oryzae	32.21	5.00e-64	239.00
IUUC-Ate-010530	Aspergillus terreus	27.89	6.00e-57	216.00
IUUC-Ame-011147	Astyanax mexicanus	90.10	5.00e-56	207.00
IUUC-Bgr-012237	Blumeria graminis	34.00	2.00e-64	240.00
IUUC-Bta-013320	Bos taurus	81.72	0.00e+00	1606.00
IUUC-Bci-013795	Botrytis cinerea	30.02	6.00e-69	256.00
IUUC-Bdi-014075	Brachypodium distachyon	37.38	2.00e-93	337.00
IUUC-Bol-016440	Brassica oleracea	35.06	2.00e-88	320.00
IUUC-Bra-016651	Brassica rapa	35.35	3.00e-87	316.00
IUUC-Cel-018692	Caenorhabditis elegans	38.36	8.00e-76	278.00
IUUC-Cja-018987	Callithrix jacchus	82.42	0.00e+00	1503.00
IUUC-Cfa-020132	Canis familiaris	81.74	0.00e+00	1562.00
IUUC-Cpo-021484	Cavia porcellus	82.13	0.00e+00	1598.00
IUUC-Cre-022846	Chlamydomonas reinhardtii	35.42	1.00e-60	228.00
IUUC-Csa-023081	Chlorocebus sabaeus	82.94	0.00e+00	1600.00
IUUC-Cin-025182	Ciona intestinalis	56.15	1.00e-161	563.00
IUUC-Csv-026154	Ciona savignyi	57.35	9.00e-158	550.00
IUUC-Cgl-026655	Colletotrichum gloeosporioides	31.32	1.00e-67	251.00
IUUC-Cne-026891	Cryptococcus neoformans	40.70	6.00e-83	301.00
IUUC-Cme-027349	Cyanidioschyzon merolae	30.87	5.00e-52	199.00
IUUC-Dre-027655	Danio rerio	69.50	0.00e+00	1393.00
IUUC-Dno-029557	Dasypus novemcinctus	74.66	0.00e+00	983.00
IUUC-Dor-030687	Dipodomys ordii	76.47	0.00e+00	710.00
IUUC-Dse-031334	Dothistroma septosporum	30.99	1.00e-64	241.00
IUUC-Dme-031746	Drosophila melanogaster	55.46	3.00e-160	559.00
IUUC-Ete-032384	Echinops telfairi	78.38	0.00e+00	1482.00
IUUC-Eca-033430	Equus caballus	82.54	0.00e+00	1560.00
IUUC-Fca-036121	Felis catus	82.22	0.00e+00	1563.00
IUUC-Fal-036817	Ficedula albicollis	87.55	0.00e+00	1704.00
IUUC-Fox-037906	Fusarium oxysporum	31.33	3.00e-68	253.00
IUUC-Fso-038409	Fusarium solani	32.24	4.00e-69	256.00
IUUC-Gmo-039151	Gadus morhua	87.06	0.00e+00	714.00
IUUC-Ggr-040016	Gaeumannomyces graminis	33.86	3.00e-70	259.00
IUUC-Gga-040936	Gallus gallus	88.49	0.00e+00	1781.00
IUUC-Gac-041405	Gasterosteus aculeatus	60.77	0.00e+00	1219.00
IUUC-Gma-044252	Glycine max	35.66	1.00e-88	321.00
IUUC-Ggo-045430	Gorilla gorilla	82.86	0.00e+00	1594.00
IUUC-Hsa-046442	Homo sapiens	82.85	0.00e+00	1597.00
IUUC-Hvu-047587	Hordeum vulgare	36.46	5.00e-80	292.00
IUUC-Itr-048910	Ictidomys tridecemlineatus	94.67	7.00e-170	588.00
IUUC-Kpa-049145	Komagataella pastoris	28.48	3.00e-60	226.00
IUUC-Lch-050474	Latimeria chalumnae	75.91	0.00e+00	1439.00
IUUC-Lpe-051209	Leersia perrieri	35.67	1.00e-84	307.00
IUUC-Loc-052119	Lepisosteus oculatus	72.62	0.00e+00	1413.00
IUUC-Lma-053237	Leptosphaeria maculans	32.09	5.00e-69	256.00
IUUC-Laf-053718	Loxodonta africana	83.80	0.00e+00	1608.00
IUUC-Mcc-055621	Macaca mulatta	82.50	0.00e+00	1508.00
IUUC-Meu-055914	Macropus eugenii	78.08	0.00e+00	923.00
IUUC-Mor-057090	Magnaporthe oryzae	34.00	1.00e-67	251.00
IUUC-Mpo-057364	Magnaporthe poae	32.22	9.00e-72	265.00
IUUC-Mtr-058691	Medicago truncatula	35.91	6.00e-88	318.00
IUUC-Mla-058914	Melampsora laricipopulina	36.00	3.00e-86	313.00
IUUC-Mga-060181	Meleagris gallopavo	86.52	0.00e+00	1736.00
IUUC-Mvi-060432	Microbotryum violaceum	38.04	1.00e-75	278.00
IUUC-Mmr-060871	Microcebus murinus	82.65	0.00e+00	1639.00
IUUC-Mdo-062301	Monodelphis domestica	84.31	0.00e+00	1625.00
IUUC-Mmu-063888	Mus musculus	81.07	0.00e+00	1576.00
IUUC-Mac-065137	Musa acuminata	37.66	3.00e-89	323.00
IUUC-Mpu-066732	Mustela putorius furo	82.31	0.00e+00	1588.00
IUUC-Mlu-067542	Myotis lucifugus	81.56	0.00e+00	1543.00
IUUC-Nfi-068396	Neosartorya fischeri	32.47	9.00e-60	225.00
IUUC-Ncr-068842	Neurospora crassa	30.97	6.00e-70	259.00
IUUC-Nle-070156	Nomascus leucogenys	83.14	0.00e+00	1606.00
IUUC-Opr-070808	Ochotona princeps	81.36	0.00e+00	1263.00
IUUC-Ont-072105	Oreochromis niloticus	67.47	0.00e+00	1359.00
IUUC-Ocu-074962	Oryctolagus cuniculus	83.04	0.00e+00	1580.00
IUUC-Oba-075178	Oryza barthii	36.58	2.00e-91	330.00
IUUC-Obr-076399	Oryza brachyantha	36.09	8.00e-92	331.00
IUUC-Ogu-078797	Oryza glumaepatula	36.58	2.00e-91	330.00
IUUC-Oin-080085	Oryza indica	35.32	2.00e-78	287.00
IUUC-Olo-081048	Oryza longistaminata	40.72	7.00e-66	246.00
IUUC-Ome-081324	Oryza meridionalis	36.38	3.00e-91	329.00
IUUC-Oni-082548	Oryza nivara	36.58	3.00e-91	330.00
IUUC-Opu-084008	Oryza punctata	41.33	5.00e-90	325.00
IUUC-Oru-084339	Oryza rufipogon	36.19	8.00e-91	328.00
IUUC-Osa-085782	Oryza sativa	36.19	8.00e-91	328.00
IUUC-Ola-087302	Oryzias latipes	62.18	0.00e+00	1208.00
IUUC-Olu-087611	Ostreococcus lucimarinus	36.38	1.00e-88	321.00
IUUC-Oga-087935	Otolemur garnettii	82.60	0.00e+00	1565.00
IUUC-Oar-089229	Ovis aries	63.16	0.00e+00	999.00
IUUC-Ptr-090715	Pan troglodytes	82.85	0.00e+00	1597.00
IUUC-Pan-092318	Papio anubis	82.78	0.00e+00	1570.00
IUUC-Psi-094053	Pelodiscus sinensis	87.63	0.00e+00	1731.00
IUUC-Pno-094985	Phaeosphaeria nodorum	32.85	5.00e-60	226.00
IUUC-Ppa-095819	Physcomitrella patens	36.21	1.00e-89	324.00
IUUC-Pfo-096857	Poecilia formosa	66.79	0.00e+00	1312.00
IUUC-Pab-098047	Pongo abelii	82.94	0.00e+00	1600.00
IUUC-Pop-099587	Populus trichocarpa	38.54	8.00e-92	332.00
IUUC-Pca-100558	Procavia capensis	82.12	0.00e+00	648.00
IUUC-Ppe-101261	Prunus persica	37.37	8.00e-90	325.00
IUUC-Pva-102683	Pteropus vampyrus	82.94	0.00e+00	1591.00
IUUC-Pgr-103660	Puccinia graminis	40.38	1.00e-77	284.00
IUUC-Ptt-103900	Puccinia triticina	34.26	2.00e-79	290.00
IUUC-Pte-104209	Pyrenophora teres	32.61	2.00e-67	251.00
IUUC-Pyt-104802	Pyrenophora triticirepentis	32.75	4.00e-67	249.00
IUUC-Rno-105566	Rattus norvegicus	80.98	0.00e+00	1594.00
IUUC-Sce-106291	Saccharomyces cerevisiae	32.59	3.00e-62	233.00
IUUC-Sha-107514	Sarcophilus harrisii	80.08	0.00e+00	1494.00
IUUC-Sja-107833	Schizosaccharomyces japonicus	35.20	7.00e-82	298.00
IUUC-Spo-108162	Schizosaccharomyces pombe	37.44	5.00e-79	289.00
IUUC-Smo-109186	Selaginella moellendorffii	40.35	7.00e-89	322.00
IUUC-Sit-110730	Setaria italica	37.08	7.00e-93	335.00
IUUC-Sly-111547	Solanum lycopersicum	37.47	1.00e-90	328.00
IUUC-Stu-112705	Solanum tuberosum	37.05	2.00e-91	330.00
IUUC-Sar-113222	Sorex araneus	77.49	0.00e+00	1395.00
IUUC-Sbi-114272	Sorghum bicolor	38.11	2.00e-95	343.00
IUUC-Sre-115061	Sporisorium reilianum	34.91	4.00e-77	283.00
IUUC-Ssc-116364	Sus scrofa	82.66	0.00e+00	1632.00
IUUC-Tgu-116645	Taeniopygia guttata	88.04	0.00e+00	1735.00
IUUC-Tru-117590	Takifugu rubripes	66.67	0.00e+00	1324.00
IUUC-Tsy-119212	Tarsius syrichta	80.62	0.00e+00	896.00
IUUC-Tni-119915	Tetraodon nigroviridis	66.13	0.00e+00	1289.00
IUUC-Tca-121765	Theobroma cacao	37.07	4.00e-91	329.00
IUUC-Tre-121887	Trichoderma reesei	30.61	2.00e-61	230.00
IUUC-Tvi-122262	Trichoderma virens	29.75	7.00e-61	229.00
IUUC-Tae-124148	Triticum aestivum	44.81	5.00e-38	152.00
IUUC-Tur-126483	Triticum urartu	37.77	1.00e-92	334.00
IUUC-Tme-127202	Tuber melanosporum	30.12	5.00e-58	219.00
IUUC-Tbe-127350	Tupaia belangeri	76.68	4.00e-174	605.00
IUUC-Ttr-129077	Tursiops truncatus	79.07	0.00e+00	1567.00
IUUC-Uma-129465	Ustilago maydis	35.67	7.00e-80	292.00
IUUC-Vda-129844	Verticillium dahliae	33.92	1.00e-68	254.00
IUUC-Vvi-131397	Vitis vinifera	37.00	1.00e-91	330.00
IUUC-Xtr-132057	Xenopus tropicalis	82.70	0.00e+00	996.00
IUUC-Xma-134139	Xiphophorus maculatus	68.37	0.00e+00	820.00
IUUC-Yli-134424	Yarrowia lipolytica	31.18	2.00e-64	241.00
IUUC-Zma-135839	Zea mays	37.43	1.00e-91	331.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence