iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sit-110730

Ensembl Protein ID

Si000161m

UniProt Accession

K3XE44; K3XE44_SETIT

Genbank Protein ID

KQL04762.1

Protein Name

Protein HIRA

Genbank Nucleotide ID

CM003532

Gene Name

LOC101782572; SETIT_000161mg

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Si000161m.g	Si000161m	Si000161m

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-21	76.3	123	160
UBD/Beta-Prp	8.80e-40	137.7	11	208

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gHt++v +l++ +d  +l+sGs D+t+++W+++ g ++
   Q: 123  GHTADVVDLSWsPDdSTLASGSLDNTVHIWNMTNGICT 160
           8***********77799****************99886 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkl...........lrslsgheaevtavkfspdgkilvtgseDrtikvw................. 79
           h+  +i ++++ p++  +atg+ d+++++w++++ ++           l+++ +h + v++v++ ++g +l++gs+D++i +                  
   Q: 11   HEGLQIFSIDIQPGSLRFATGGGDQKVRIWSMKSVDKdnanhdssqrlLATMRDHFGSVNCVRWAKHGRYLASGSDDQVILIHerkagsgtsefgsgepp 110
           56667888999999********************9999*********************************************88888888888888888 PP
   S: 80   dlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltggh 179
           d+++ k ++tl+gh+++v++ls+sp++++l+sGs d+t+++w++ +g c   +l+gh+++v +v+++p g+ ++s s+D+tv +W+ +  +l ++ +g h
   Q: 111  DVENWKVIMTLRGHTADVVDLSWSPDDSTLASGSLDNTVHIWNMTNGICTA-VLRGHSSLVKGVTWDPIGSFIASQSDDKTVIIWRTSDWSLAHKTEG-H 208
           888************************************************.*********************************9988888888776.4 PP

Organism

Setaria italica

Functional Description
(View)

Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

Protein Sequence
(Fasta)

MITEKPSWIR HEGLQIFSID IQPGSLRFAT GGGDQKVRIW SMKSVDKDNA NHDSSQRLLA 60
TMRDHFGSVN CVRWAKHGRY LASGSDDQVI LIHERKAGSG TSEFGSGEPP DVENWKVIMT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCTCGGCCT CCCTAACCCT AACGAGGGCT GCGGCGGTCG CCGGTCACCG TCAGCCGCGA 60
AGCGCGCGGC GGGAAGCGGC AGGCAGGCGC GCGCTGGGCG GCTGCAGCTC GCGGCCTCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR003143--Cyt_cd1_C
IPR031120--HIR1
IPR011494--Hira
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07569--Hira
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0016569--P:covalent chromatin modification
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

KEGG

sita:101782572

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003197	Anas platyrhynchos	37.55	9.00e-86	311.00
IUUC-Aca-004733	Anolis carolinensis	37.67	4.00e-89	322.00
IUUC-Aly-005446	Arabidopsis lyrata	65.95	0.00e+00	1254.00
IUUC-Ath-007627	Arabidopsis thaliana	63.65	0.00e+00	1247.00
IUUC-Acl-008104	Aspergillus clavatus	33.58	4.00e-72	266.00
IUUC-Afl-008591	Aspergillus flavus	30.80	1.00e-67	251.00
IUUC-Afu-008781	Aspergillus fumigatus	33.47	5.00e-67	248.00
IUUC-Ani-009272	Aspergillus nidulans	29.67	2.00e-58	220.00
IUUC-Ang-009655	Aspergillus niger	35.20	6.00e-69	255.00
IUUC-Aor-010119	Aspergillus oryzae	30.38	2.00e-67	249.00
IUUC-Bgr-012237	Blumeria graminis	32.17	8.00e-66	244.00
IUUC-Bdi-014075	Brachypodium distachyon	84.91	0.00e+00	1739.00
IUUC-Bol-016440	Brassica oleracea	65.33	0.00e+00	1233.00
IUUC-Bra-016651	Brassica rapa	64.38	0.00e+00	1201.00
IUUC-Cja-018987	Callithrix jacchus	36.54	2.00e-76	280.00
IUUC-Cin-025182	Ciona intestinalis	36.49	3.00e-84	306.00
IUUC-Cme-027349	Cyanidioschyzon merolae	31.06	6.00e-56	212.00
IUUC-Dre-027655	Danio rerio	36.22	2.00e-85	310.00
IUUC-Dse-031334	Dothistroma septosporum	26.46	3.00e-87	316.00
IUUC-Ete-032384	Echinops telfairi	33.87	1.00e-64	241.00
IUUC-Eca-033430	Equus caballus	37.07	7.00e-83	301.00
IUUC-Fal-036817	Ficedula albicollis	37.27	1.00e-84	307.00
IUUC-Fox-037906	Fusarium oxysporum	35.14	2.00e-71	263.00
IUUC-Gga-040936	Gallus gallus	37.87	1.00e-89	323.00
IUUC-Gma-044252	Glycine max	69.01	0.00e+00	1419.00
IUUC-Lch-050474	Latimeria chalumnae	37.85	8.00e-82	298.00
IUUC-Lpe-051209	Leersia perrieri	84.50	0.00e+00	1669.00
IUUC-Loc-052119	Lepisosteus oculatus	37.01	2.00e-82	300.00
IUUC-Lma-053237	Leptosphaeria maculans	33.65	1.00e-65	244.00
IUUC-Meu-055914	Macropus eugenii	38.58	1.00e-56	214.00
IUUC-Mor-057090	Magnaporthe oryzae	35.51	1.00e-68	254.00
IUUC-Mpo-057364	Magnaporthe poae	34.42	8.00e-69	254.00
IUUC-Mtr-057744	Medicago truncatula	71.55	0.00e+00	1397.00
IUUC-Mga-060181	Meleagris gallopavo	37.90	2.00e-85	310.00
IUUC-Mdo-062301	Monodelphis domestica	37.67	2.00e-87	316.00
IUUC-Mmu-063888	Mus musculus	37.48	4.00e-88	318.00
IUUC-Mpu-066732	Mustela putorius furo	42.45	1.00e-82	301.00
IUUC-Nfi-068396	Neosartorya fischeri	33.33	8.00e-67	248.00
IUUC-Ncr-068842	Neurospora crassa	33.33	8.00e-72	265.00
IUUC-Nle-070156	Nomascus leucogenys	37.28	2.00e-87	317.00
IUUC-Oba-075178	Oryza barthii	86.51	0.00e+00	1645.00
IUUC-Obr-076399	Oryza brachyantha	85.94	0.00e+00	1664.00
IUUC-Ogu-078797	Oryza glumaepatula	86.51	0.00e+00	1645.00
IUUC-Oin-080085	Oryza indica	86.01	0.00e+00	1559.00
IUUC-Ome-081324	Oryza meridionalis	86.72	0.00e+00	1645.00
IUUC-Oni-082548	Oryza nivara	85.77	0.00e+00	1640.00
IUUC-Opu-084008	Oryza punctata	86.69	0.00e+00	843.00
IUUC-Oru-084339	Oryza rufipogon	86.30	0.00e+00	1640.00
IUUC-Osa-085782	Oryza sativa	86.30	0.00e+00	1640.00
IUUC-Ola-087302	Oryzias latipes	35.02	2.00e-79	290.00
IUUC-Olu-087611	Ostreococcus lucimarinus	35.43	7.00e-155	540.00
IUUC-Oga-087935	Otolemur garnettii	37.20	5.00e-84	305.00
IUUC-Psi-094053	Pelodiscus sinensis	37.67	6.00e-85	308.00
IUUC-Pno-094985	Phaeosphaeria nodorum	31.93	1.00e-59	224.00
IUUC-Ppa-095499	Physcomitrella patens	49.61	0.00e+00	927.00
IUUC-Pca-100558	Procavia capensis	49.22	8.00e-49	188.00
IUUC-Ppe-101261	Prunus persica	71.25	0.00e+00	1395.00
IUUC-Pgr-103660	Puccinia graminis	36.22	2.00e-61	229.00
IUUC-Ptt-103900	Puccinia triticina	32.08	6.00e-62	231.00
IUUC-Rno-105566	Rattus norvegicus	37.28	1.00e-87	317.00
IUUC-Sar-113222	Sorex araneus	36.23	2.00e-76	280.00
IUUC-Sre-115061	Sporisorium reilianum	33.79	3.00e-70	259.00
IUUC-Tgu-116645	Taeniopygia guttata	37.27	1.00e-84	307.00
IUUC-Tru-117590	Takifugu rubripes	36.61	1.00e-86	314.00
IUUC-Tni-119915	Tetraodon nigroviridis	37.65	7.00e-87	314.00
IUUC-Tme-127202	Tuber melanosporum	28.06	5.00e-50	192.00
IUUC-Ttr-129077	Tursiops truncatus	33.67	1.00e-73	271.00
IUUC-Vda-129844	Verticillium dahliae	33.41	5.00e-68	252.00
IUUC-Vvi-131397	Vitis vinifera	71.33	0.00e+00	1434.00
IUUC-Xtr-132057	Xenopus tropicalis	38.58	2.00e-89	323.00
IUUC-Yli-134424	Yarrowia lipolytica	36.02	8.00e-67	248.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence