iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088945

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03058919

Gene Name

PIAS4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000001656.2	ENSOGAT00000001657.2	ENSOGAP00000001477.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	95.89	0.00e+00	934.00	IUUC-Hsa-045784
E3 activity/RING/RING	27.42	8.00e-29	123.00	IUUC-Sce-106398

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MAAELVEAKN MVMSFRVSDL QMLLGFVGRS KSGLKHELVT RALQLVQFDC SPELFKKIKE 60
LYETRYAKKN SEPVPQPHRP LDPLTMHSTY DRAGAVPRTP LSGPNIDYPV LYGKYLNGLG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCGG AGCTGGTGGA GGCTAAAGTG AGTAATCGGC GGCGGCGCCG GCCAGGGCGG 60
GCGAAGGGGT AGGGGCCGGA CTGCGGGCTG GGGCCTGCGC CTTCTGCCCA GGGACTTACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027224--PIAS4
IPR023321--PINIT
IPR003034--SAP_dom
IPR004181--Znf_MIZ

PROSITE

PS51466--PINIT
PS50800--SAP
PS51044--ZF_SP_RING

Pfam

PF14324--PINIT
PF02891--zf-MIZ

SMART

SM00513--SAP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005654--C:nucleoplasm
GO:1990234--C:transferase complex
GO:0003677--F:DNA binding
GO:0061665--F:SUMO ligase activity
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1902174--P:positive regulation of keratinocyte apoptotic process
GO:0033235--P:positive regulation of protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001745	Ailuropoda melanoleuca	92.14	0.00e+00	885.00
IUUC-Apl-003765	Anas platyrhynchos	81.82	0.00e+00	816.00
IUUC-Ame-010763	Astyanax mexicanus	59.56	1.00e-146	513.00
IUUC-Bta-012369	Bos taurus	94.35	0.00e+00	912.00
IUUC-Cja-019450	Callithrix jacchus	94.13	0.00e+00	917.00
IUUC-Cfa-020933	Canis familiaris	94.17	0.00e+00	905.00
IUUC-Cpo-022112	Cavia porcellus	92.83	0.00e+00	870.00
IUUC-Csa-023913	Chlorocebus sabaeus	83.30	0.00e+00	751.00
IUUC-Cgl-026533	Colletotrichum gloeosporioides	27.48	8.00e-34	138.00
IUUC-Dre-027609	Danio rerio	58.78	4.00e-142	497.00
IUUC-Dno-029664	Dasypus novemcinctus	74.94	2.00e-154	539.00
IUUC-Ete-032988	Echinops telfairi	92.74	1.00e-172	599.00
IUUC-Eca-034430	Equus caballus	92.94	0.00e+00	880.00
IUUC-Fca-035968	Felis catus	97.95	2.00e-169	587.00
IUUC-Fal-037449	Ficedula albicollis	83.00	0.00e+00	799.00
IUUC-Fso-038103	Fusarium solani	34.72	9.00e-27	114.00
IUUC-Gmo-038925	Gadus morhua	60.54	4.00e-138	484.00
IUUC-Ggr-039896	Gaeumannomyces graminis	32.48	2.00e-29	124.00
IUUC-Gga-040362	Gallus gallus	85.55	0.00e+00	849.00
IUUC-Gac-042353	Gasterosteus aculeatus	58.82	2.00e-133	469.00
IUUC-Ggo-044810	Gorilla gorilla	93.35	0.00e+00	884.00
IUUC-Hsa-045784	Homo sapiens	95.89	0.00e+00	933.00
IUUC-Itr-048486	Ictidomys tridecemlineatus	90.89	0.00e+00	885.00
IUUC-Lch-049727	Latimeria chalumnae	72.49	2.00e-153	535.00
IUUC-Loc-052354	Lepisosteus oculatus	54.38	6.00e-124	437.00
IUUC-Laf-054261	Loxodonta africana	92.62	0.00e+00	911.00
IUUC-Mcc-054931	Macaca mulatta	95.30	0.00e+00	918.00
IUUC-Meu-056468	Macropus eugenii	87.70	0.00e+00	870.00
IUUC-Mpo-057405	Magnaporthe poae	33.06	9.00e-29	121.00
IUUC-Mtr-058267	Medicago truncatula	33.33	4.00e-18	87.00
IUUC-Mla-058882	Melampsora laricipopulina	36.84	4.00e-23	102.00
IUUC-Mga-059981	Meleagris gallopavo	88.83	0.00e+00	706.00
IUUC-Mvi-060421	Microbotryum violaceum	29.10	7.00e-28	119.00
IUUC-Mmr-061181	Microcebus murinus	94.86	0.00e+00	882.00
IUUC-Mdo-062345	Monodelphis domestica	87.50	0.00e+00	871.00
IUUC-Mmu-063197	Mus musculus	87.77	0.00e+00	859.00
IUUC-Mpu-066275	Mustela putorius furo	92.22	0.00e+00	897.00
IUUC-Mlu-067194	Myotis lucifugus	93.40	0.00e+00	906.00
IUUC-Ncr-068929	Neurospora crassa	27.70	3.00e-27	116.00
IUUC-Ont-072227	Oreochromis niloticus	58.82	5.00e-139	487.00
IUUC-Oba-075731	Oryza barthii	42.86	1.00e-20	95.50
IUUC-Obr-076179	Oryza brachyantha	32.58	2.00e-20	94.70
IUUC-Ogl-077808	Oryza glaberrima	42.86	1.00e-20	95.50
IUUC-Ogu-078271	Oryza glumaepatula	42.86	1.00e-20	95.50
IUUC-Oin-079070	Oryza indica	42.86	9.00e-21	95.90
IUUC-Oru-084716	Oryza rufipogon	42.86	8.00e-21	95.90
IUUC-Ola-086865	Oryzias latipes	57.43	6.00e-137	480.00
IUUC-Oar-089412	Ovis aries	91.41	0.00e+00	870.00
IUUC-Ptr-091550	Pan troglodytes	86.32	0.00e+00	647.00
IUUC-Pan-092183	Papio anubis	96.09	0.00e+00	931.00
IUUC-Psi-093003	Pelodiscus sinensis	83.79	0.00e+00	831.00
IUUC-Pfo-096704	Poecilia formosa	59.23	3.00e-141	495.00
IUUC-Pab-097923	Pongo abelii	98.95	0.00e+00	779.00
IUUC-Pca-100249	Procavia capensis	77.69	2.00e-144	504.00
IUUC-Pva-102562	Pteropus vampyrus	89.29	0.00e+00	840.00
IUUC-Rno-105762	Rattus norvegicus	88.74	0.00e+00	862.00
IUUC-Sce-106398	Saccharomyces cerevisiae	34.10	1.00e-28	121.00
IUUC-Sha-107253	Sarcophilus harrisii	86.72	0.00e+00	863.00
IUUC-Sja-107662	Schizosaccharomyces japonicus	31.41	4.00e-29	123.00
IUUC-Sar-113149	Sorex araneus	85.45	1.00e-126	446.00
IUUC-Ssc-115241	Sus scrofa	94.15	0.00e+00	915.00
IUUC-Tgu-116884	Taeniopygia guttata	83.76	0.00e+00	802.00
IUUC-Tru-118031	Takifugu rubripes	59.28	5.00e-145	507.00
IUUC-Tni-119766	Tetraodon nigroviridis	59.23	3.00e-140	491.00
IUUC-Ttr-128556	Tursiops truncatus	84.80	0.00e+00	749.00
IUUC-Xtr-131866	Xenopus tropicalis	77.46	0.00e+00	764.00
IUUC-Xma-133963	Xiphophorus maculatus	59.50	2.00e-135	475.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence