iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-097923

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01036734

Gene Name

PIAS4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000009394.2	ENSPPYT00000010949.2	ENSPPYP00000010535.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	99.74	0.00e+00	783.00	IUUC-Hsa-045784

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pongo abelii

Protein Sequence
(Fasta)

MAAELVDAKN MVMSFRVSDL QMLLGFVGRS KSGLKHELVT RALQLVQFDC SPELFKKIKE 60
LYETRYAKKN SEPAPQPHRP LDPLTMHSTY DRAGAVPRTP LAGPNIDYPV LYGKYLNGLG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTGACGCGA CGGCTGGGGG CTCCCGGCGC GGGGGACTCT GGTGGCCAAT ATGGCGGCGG 60
AGCTGGTGGA TGCCAAAGTG AGTGAGCGGT GGCGGCCCCG GCCGGGGCAA GTGGGCGAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027224--PIAS4
IPR023321--PINIT
IPR003034--SAP_dom
IPR004181--Znf_MIZ

PROSITE

PS51466--PINIT
PS50800--SAP
PS51044--ZF_SP_RING

Pfam

PF14324--PINIT
PF02891--zf-MIZ

SMART

SM00513--SAP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005654--C:nucleoplasm
GO:1990234--C:transferase complex
GO:0003677--F:DNA binding
GO:0061665--F:SUMO ligase activity
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1902174--P:positive regulation of keratinocyte apoptotic process
GO:0033235--P:positive regulation of protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001745	Ailuropoda melanoleuca	95.48	0.00e+00	739.00
IUUC-Apl-003765	Anas platyrhynchos	89.89	0.00e+00	701.00
IUUC-Ame-010763	Astyanax mexicanus	61.54	3.00e-134	471.00
IUUC-Bta-012369	Bos taurus	97.90	0.00e+00	767.00
IUUC-Cja-019450	Callithrix jacchus	98.43	0.00e+00	766.00
IUUC-Cfa-020933	Canis familiaris	97.90	0.00e+00	768.00
IUUC-Cpo-022112	Cavia porcellus	96.59	0.00e+00	763.00
IUUC-Csa-023913	Chlorocebus sabaeus	85.07	8.00e-178	616.00
IUUC-Cgl-026533	Colletotrichum gloeosporioides	28.61	1.00e-31	130.00
IUUC-Dre-027609	Danio rerio	60.89	3.00e-131	461.00
IUUC-Dno-029664	Dasypus novemcinctus	92.74	8.00e-127	447.00
IUUC-Ete-032988	Echinops telfairi	92.74	1.00e-173	602.00
IUUC-Eca-034430	Equus caballus	95.79	0.00e+00	750.00
IUUC-Fca-035968	Felis catus	97.60	1.00e-169	588.00
IUUC-Fal-037449	Ficedula albicollis	89.10	0.00e+00	679.00
IUUC-Gmo-038925	Gadus morhua	59.84	4.00e-129	454.00
IUUC-Gga-040362	Gallus gallus	91.10	0.00e+00	719.00
IUUC-Gac-042353	Gasterosteus aculeatus	61.15	1.00e-126	446.00
IUUC-Ggo-044810	Gorilla gorilla	96.59	0.00e+00	746.00
IUUC-Hsa-045784	Homo sapiens	99.74	0.00e+00	781.00
IUUC-Itr-048486	Ictidomys tridecemlineatus	96.25	0.00e+00	745.00
IUUC-Lch-049727	Latimeria chalumnae	72.22	4.00e-153	533.00
IUUC-Loc-052354	Lepisosteus oculatus	54.33	4.00e-110	391.00
IUUC-Laf-054261	Loxodonta africana	96.85	0.00e+00	764.00
IUUC-Mcc-054931	Macaca mulatta	99.48	0.00e+00	777.00
IUUC-Meu-056468	Macropus eugenii	92.91	0.00e+00	736.00
IUUC-Mga-059981	Meleagris gallopavo	91.18	0.00e+00	709.00
IUUC-Mmr-061181	Microcebus murinus	95.70	0.00e+00	726.00
IUUC-Mdo-062345	Monodelphis domestica	92.91	0.00e+00	736.00
IUUC-Mmu-063197	Mus musculus	93.44	0.00e+00	729.00
IUUC-Mpu-066275	Mustela putorius furo	96.06	0.00e+00	753.00
IUUC-Mlu-067194	Myotis lucifugus	97.13	0.00e+00	760.00
IUUC-Ont-072227	Oreochromis niloticus	60.63	2.00e-128	452.00
IUUC-Ola-086865	Oryzias latipes	60.63	6.00e-128	450.00
IUUC-Oga-088945	Otolemur garnettii	98.95	0.00e+00	776.00
IUUC-Oar-089412	Ovis aries	97.86	0.00e+00	751.00
IUUC-Ptr-091550	Pan troglodytes	87.11	0.00e+00	654.00
IUUC-Pan-092183	Papio anubis	99.48	0.00e+00	778.00
IUUC-Psi-093003	Pelodiscus sinensis	89.27	0.00e+00	704.00
IUUC-Pfo-096704	Poecilia formosa	60.99	9.00e-131	460.00
IUUC-Pca-100249	Procavia capensis	79.91	6.00e-104	370.00
IUUC-Pva-102562	Pteropus vampyrus	94.62	0.00e+00	721.00
IUUC-Rno-105762	Rattus norvegicus	93.18	0.00e+00	728.00
IUUC-Sha-107253	Sarcophilus harrisii	91.86	0.00e+00	728.00
IUUC-Sar-113149	Sorex araneus	85.45	2.00e-127	449.00
IUUC-Ssc-115241	Sus scrofa	97.64	0.00e+00	766.00
IUUC-Tgu-116884	Taeniopygia guttata	89.87	0.00e+00	688.00
IUUC-Tru-118031	Takifugu rubripes	61.15	3.00e-134	472.00
IUUC-Tni-119766	Tetraodon nigroviridis	61.15	2.00e-129	456.00
IUUC-Ttr-128556	Tursiops truncatus	86.54	0.00e+00	635.00
IUUC-Xtr-131866	Xenopus tropicalis	82.52	0.00e+00	662.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence