iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052638

Ensembl Protein ID

ENSLOCP00000004686.1

UniProt Accession

W5M8H8; W5M8H8_LEPOC

Genbank Protein ID

ENSLOCP00000004686

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01018261

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000003921.1	ENSLOCT00000004694.1	ENSLOCP00000004686.1
ENSLOCG00000003921.1	ENSLOCT00000004709.1	ENSLOCP00000004701.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-28	97.2	320	350
E3 adaptor/Cullin RING/APC_C/CDC20	4.50e-131	436.8	185	491

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH+ +v++l++ +d ++l+sG++D+ ++vW 
   Q: 320  GHSQEVCGLEWsPDgKYLASGGNDNLVYVWQ 350
           8***********999***************6 PP

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+++ldap+lr+dfylnL+dWss+nv+avaL++svylw+a+t ++++l++l +e+d++t+vsw++eg++la+Gt++g+v+++Dv+++k+
   Q: 185  PDRILDAPDLRNDFYLNLIDWSSQNVMAVALHNSVYLWNASTCEITQLMKLeNEEDYITCVSWVKEGNFLAIGTSDGKVQLWDVDSQKR 273
           689************************************************899*********************************** PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse....Plk 173
           +r++++h+ rvg+LsWn+++lssGsr+g+i+h+dvrv++++++tl++h+qevCGl+w+ d+k+LasGGnDn v vw+  ++      l+
   Q: 274  LRSMASHTVRVGCLSWNNHILSSGSRSGHIHHHDVRVANHHVATLAGHSQEVCGLEWSPDGKYLASGGNDNLVYVWQGVQEGttqsALH 362
           ****************************************************************************987665555699* PP
   S: 174  kfkehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvae 262
           +f+ h++avka+aw+Pwq++ La+GGGt+D++i++wn+++ga++   d++sqv+sl++s ++kel+s+hG +  ++++wkyp ++kv+e
   Q: 363  TFNLHRGAVKAVAWCPWQPTTLATGGGTSDQHIRIWNVNSGACFLYKDVQSQVTSLAFSSNYKELISSHGDPLDSLIIWKYPAMTKVTE 451
           ***************************************************************************************** PP
   S: 263  lkgheaRvlslalspdgeaivtaagDetlrfwklfdkkka 302
           l gh+ Rvl+++lspdg+++++ a+Det+r+wk+f+ ++ 
   Q: 452  LAGHQGRVLTMTLSPDGSTVASIAADETVRLWKCFELDPL 491
           ***********************************98875 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

RLLTSMAHFE FENDLQNILK LDMPITNAPM ARWQRKASST SGAGQGSLNS SSVSPGKSMS 60
RSLSLSKTPA KTPGRNTSKA QNTPSKAGGD RYIPHRNPKQ MDVASFLMSK ENEPVESSSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGAGTTTAT CTCACCTGTT GACAACTAAA ATAAATATTA ACAACATTCT TTACTTCACA 60
CCAAAGGTAC AAAAATGTAA ATAAGTGAGC TCTCTAAGGT AATCCTAGCT TCCAAAATCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033187--CDC20
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000638	Aegilops tauschii	42.16	4.00e-97	348.00
IUUC-Aml-001545	Ailuropoda melanoleuca	62.72	0.00e+00	638.00
IUUC-Apl-003255	Anas platyrhynchos	64.46	6.00e-176	610.00
IUUC-Aca-004920	Anolis carolinensis	63.06	0.00e+00	630.00
IUUC-Aly-006303	Arabidopsis lyrata	44.29	4.00e-95	341.00
IUUC-Ame-010850	Astyanax mexicanus	67.93	5.00e-102	363.00
IUUC-Bgr-012059	Blumeria graminis	45.45	5.00e-89	322.00
IUUC-Bta-012625	Bos taurus	63.31	0.00e+00	639.00
IUUC-Bci-013607	Botrytis cinerea	44.97	7.00e-90	324.00
IUUC-Bdi-014569	Brachypodium distachyon	42.40	6.00e-89	321.00
IUUC-Bol-015368	Brassica oleracea	44.39	5.00e-95	342.00
IUUC-Cja-019132	Callithrix jacchus	62.72	0.00e+00	638.00
IUUC-Cfa-020780	Canis familiaris	63.12	0.00e+00	639.00
IUUC-Cpo-022223	Cavia porcellus	63.12	2.00e-172	598.00
IUUC-Cre-022701	Chlamydomonas reinhardtii	46.73	4.00e-101	361.00
IUUC-Csa-023666	Chlorocebus sabaeus	63.12	0.00e+00	639.00
IUUC-Cho-024920	Choloepus hoffmanni	61.03	5.00e-105	374.00
IUUC-Cin-025675	Ciona intestinalis	47.21	1.00e-118	420.00
IUUC-Csv-026019	Ciona savignyi	46.98	2.00e-116	412.00
IUUC-Cgl-026465	Colletotrichum gloeosporioides	43.87	2.00e-87	316.00
IUUC-Cne-026872	Cryptococcus neoformans	43.10	7.00e-84	304.00
IUUC-Cme-027234	Cyanidioschyzon merolae	47.09	3.00e-94	338.00
IUUC-Dre-028026	Danio rerio	64.69	0.00e+00	676.00
IUUC-Dno-028865	Dasypus novemcinctus	62.20	0.00e+00	627.00
IUUC-Dor-030958	Dipodomys ordii	62.92	0.00e+00	629.00
IUUC-Dse-031391	Dothistroma septosporum	46.55	6.00e-91	328.00
IUUC-Dme-031905	Drosophila melanogaster	46.99	1.00e-129	456.00
IUUC-Ete-032387	Echinops telfairi	59.17	7.00e-177	613.00
IUUC-Eca-033522	Equus caballus	54.97	6.00e-161	560.00
IUUC-Eeu-035059	Erinaceus europaeus	58.46	3.00e-156	545.00
IUUC-Fca-036346	Felis catus	64.14	5.00e-165	573.00
IUUC-Fal-037558	Ficedula albicollis	64.05	1.00e-180	625.00
IUUC-Fox-037850	Fusarium oxysporum	42.78	3.00e-87	316.00
IUUC-Fso-038375	Fusarium solani	43.06	1.00e-87	317.00
IUUC-Gmo-039284	Gadus morhua	69.80	0.00e+00	697.00
IUUC-Ggr-039864	Gaeumannomyces graminis	44.28	4.00e-88	318.00
IUUC-Gga-040790	Gallus gallus	64.96	0.00e+00	659.00
IUUC-Gac-041431	Gasterosteus aculeatus	69.09	0.00e+00	686.00
IUUC-Gma-043489	Glycine max	44.20	6.00e-96	344.00
IUUC-Ggo-045052	Gorilla gorilla	63.12	0.00e+00	639.00
IUUC-Hsa-046305	Homo sapiens	63.12	0.00e+00	639.00
IUUC-Hvu-047227	Hordeum vulgare	42.49	3.00e-95	342.00
IUUC-Itr-048461	Ictidomys tridecemlineatus	62.92	5.00e-173	600.00
IUUC-Lch-050174	Latimeria chalumnae	58.25	9.00e-155	540.00
IUUC-Lpe-050954	Leersia perrieri	43.17	4.00e-88	318.00
IUUC-Lma-052998	Leptosphaeria maculans	44.99	9.00e-92	330.00
IUUC-Laf-053742	Loxodonta africana	63.12	0.00e+00	641.00
IUUC-Mcc-054948	Macaca mulatta	63.12	0.00e+00	639.00
IUUC-Meu-056013	Macropus eugenii	60.48	2.00e-100	359.00
IUUC-Mor-057277	Magnaporthe oryzae	47.21	2.00e-85	309.00
IUUC-Mpo-057624	Magnaporthe poae	46.91	4.00e-86	311.00
IUUC-Mtr-058044	Medicago truncatula	43.12	1.00e-90	327.00
IUUC-Mga-060102	Meleagris gallopavo	63.98	0.00e+00	653.00
IUUC-Mmr-061615	Microcebus murinus	63.93	0.00e+00	633.00
IUUC-Mdo-061982	Monodelphis domestica	64.21	3.00e-158	553.00
IUUC-Mmu-063864	Mus musculus	62.52	0.00e+00	629.00
IUUC-Mpu-066502	Mustela putorius furo	62.72	0.00e+00	634.00
IUUC-Mlu-067277	Myotis lucifugus	60.31	2.00e-172	598.00
IUUC-Nle-070149	Nomascus leucogenys	62.92	0.00e+00	633.00
IUUC-Opr-070778	Ochotona princeps	62.94	2.00e-130	459.00
IUUC-Ont-071660	Oreochromis niloticus	68.04	0.00e+00	655.00
IUUC-Oan-073677	Ornithorhynchus anatinus	55.49	9.00e-147	513.00
IUUC-Ocu-073797	Oryctolagus cuniculus	63.37	0.00e+00	634.00
IUUC-Oba-075514	Oryza barthii	43.17	9.00e-88	317.00
IUUC-Obr-076018	Oryza brachyantha	44.39	1.00e-95	343.00
IUUC-Ogl-077254	Oryza glaberrima	43.17	9.00e-88	317.00
IUUC-Ogu-078562	Oryza glumaepatula	42.93	2.00e-87	316.00
IUUC-Oin-080094	Oryza indica	43.17	9.00e-88	317.00
IUUC-Olo-080449	Oryza longistaminata	43.17	6.00e-88	317.00
IUUC-Ome-081186	Oryza meridionalis	43.91	2.00e-94	340.00
IUUC-Oni-082243	Oryza nivara	43.17	9.00e-88	317.00
IUUC-Opu-084007	Oryza punctata	43.24	2.00e-87	315.00
IUUC-Oru-084357	Oryza rufipogon	43.17	2.00e-87	316.00
IUUC-Osa-086094	Oryza sativa	43.68	1.00e-87	317.00
IUUC-Ola-086907	Oryzias latipes	66.73	7.00e-176	610.00
IUUC-Olu-087647	Ostreococcus lucimarinus	45.60	7.00e-104	370.00
IUUC-Oga-088184	Otolemur garnettii	62.01	0.00e+00	627.00
IUUC-Oar-090023	Ovis aries	62.20	9.00e-168	583.00
IUUC-Ptr-090935	Pan troglodytes	62.79	1.00e-171	595.00
IUUC-Pan-091845	Papio anubis	63.12	0.00e+00	639.00
IUUC-Psi-093188	Pelodiscus sinensis	64.98	0.00e+00	672.00
IUUC-Pma-094187	Petromyzon marinus	50.58	2.00e-136	478.00
IUUC-Pno-094809	Phaeosphaeria nodorum	45.75	5.00e-91	328.00
IUUC-Ppa-095457	Physcomitrella patens	44.10	8.00e-94	337.00
IUUC-Pfo-097429	Poecilia formosa	62.94	2.00e-168	585.00
IUUC-Pab-098603	Pongo abelii	62.92	0.00e+00	638.00
IUUC-Pop-098890	Populus trichocarpa	44.77	6.00e-93	334.00
IUUC-Pca-101062	Procavia capensis	63.31	0.00e+00	636.00
IUUC-Ppe-101865	Prunus persica	43.20	2.00e-84	306.00
IUUC-Pva-102925	Pteropus vampyrus	62.72	0.00e+00	645.00
IUUC-Pte-104142	Pyrenophora teres	46.55	3.00e-91	329.00
IUUC-Pyt-104693	Pyrenophora triticirepentis	46.55	3.00e-91	329.00
IUUC-Rno-106005	Rattus norvegicus	62.72	0.00e+00	627.00
IUUC-Sha-107472	Sarcophilus harrisii	62.99	0.00e+00	630.00
IUUC-Sja-107919	Schizosaccharomyces japonicus	45.05	3.00e-87	315.00
IUUC-Spo-108075	Schizosaccharomyces pombe	45.60	5.00e-92	331.00
IUUC-Ssl-108507	Sclerotinia sclerotiorum	44.97	7.00e-89	321.00
IUUC-Smo-108922	Selaginella moellendorffii	43.82	2.00e-105	375.00
IUUC-Sit-110732	Setaria italica	42.50	3.00e-94	338.00
IUUC-Sly-111025	Solanum lycopersicum	43.03	6.00e-85	307.00
IUUC-Stu-112676	Solanum tuberosum	42.79	1.00e-86	313.00
IUUC-Sar-113092	Sorex araneus	59.96	1.00e-166	579.00
IUUC-Sbi-114207	Sorghum bicolor	43.41	6.00e-96	344.00
IUUC-Ssc-115710	Sus scrofa	62.92	0.00e+00	636.00
IUUC-Tgu-117100	Taeniopygia guttata	63.98	0.00e+00	626.00
IUUC-Tru-118184	Takifugu rubripes	61.45	1.00e-145	509.00
IUUC-Tsy-118892	Tarsius syrichta	60.00	1.00e-105	375.00
IUUC-Tni-120474	Tetraodon nigroviridis	66.27	1.00e-177	615.00
IUUC-Tca-120949	Theobroma cacao	43.50	4.00e-97	348.00
IUUC-Tre-122211	Trichoderma reesei	38.78	1.00e-86	313.00
IUUC-Tvi-122531	Trichoderma virens	44.67	1.00e-86	314.00
IUUC-Tae-123017	Triticum aestivum	42.16	9.00e-97	347.00
IUUC-Tur-126193	Triticum urartu	42.16	2.00e-96	346.00
IUUC-Tme-126905	Tuber melanosporum	46.61	8.00e-91	327.00
IUUC-Tbe-127384	Tupaia belangeri	67.57	7.00e-121	427.00
IUUC-Ttr-128511	Tursiops truncatus	63.31	0.00e+00	640.00
IUUC-Vda-129993	Verticillium dahliae	43.33	7.00e-89	321.00
IUUC-Vvi-131245	Vitis vinifera	43.98	2.00e-83	302.00
IUUC-Xtr-131993	Xenopus tropicalis	64.91	0.00e+00	644.00
IUUC-Xma-133332	Xiphophorus maculatus	66.60	0.00e+00	650.00
IUUC-Zma-135456	Zea mays	41.22	1.00e-92	333.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence