iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-021082

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03012239

Gene Name

SCAP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000013200.3	ENSCAFT00000020960.3	ENSCAFP00000019461.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.30e-14	52.7	1116	1149

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd.tl.lvsGsdDgtikvWDlrtg 33
           gH++ +t +   d t+ l+sG+ Dg i +WD+ tg
   Q: 1116 GHSGAITTVYI-DqTMvLASGGQDGAICLWDVLTG 1149
           8********88.446648*************9887 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MTLTERLREK ISQAFYNHGL LCASYPIPII LFTGLCILAC CCPLLKLPLP GTGPVEFTTP 60
VKDYSPPPVA PDHKPGEPSE RPEWYVGAPV AYIQQIFVKS SVSPWHKNLL AVDVFRSPLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGTCCA CTGTCGGTGC TGTCCAGCGC ACACCAGGCT GATCCATGGT CACTTTCCGG 60
GATGGCAGCA AGGTGACTTC AACTGAGGAT GACCCTGACT GAAAGGCTTC GTGAGAAGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR030225--SCAP
IPR000731--SSD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50156--SSD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12349--Sterol-sensing
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0015485--F:cholesterol binding
GO:0008203--P:cholesterol metabolic process
GO:0045540--P:regulation of cholesterol biosynthetic process
GO:0042304--P:regulation of fatty acid biosynthetic process
GO:0001666--P:response to hypoxia
GO:0032868--P:response to insulin
GO:0032933--P:SREBP signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001802	Ailuropoda melanoleuca	98.92	0.00e+00	1135.00
IUUC-Apl-003294	Anas platyrhynchos	76.24	0.00e+00	1698.00
IUUC-Aca-004424	Anolis carolinensis	69.92	0.00e+00	1499.00
IUUC-Bta-013478	Bos taurus	92.42	0.00e+00	2055.00
IUUC-Cel-018160	Caenorhabditis elegans	30.12	1.00e-65	245.00
IUUC-Cja-019123	Callithrix jacchus	89.99	0.00e+00	1991.00
IUUC-Cpo-022477	Cavia porcellus	84.70	0.00e+00	1875.00
IUUC-Csa-023176	Chlorocebus sabaeus	89.99	0.00e+00	1988.00
IUUC-Cin-025490	Ciona intestinalis	37.28	4.00e-89	322.00
IUUC-Csv-026115	Ciona savignyi	36.79	1.00e-131	464.00
IUUC-Dre-028008	Danio rerio	67.72	0.00e+00	1515.00
IUUC-Dno-028887	Dasypus novemcinctus	91.73	0.00e+00	1201.00
IUUC-Dor-030467	Dipodomys ordii	93.67	0.00e+00	881.00
IUUC-Dme-032087	Drosophila melanogaster	32.67	9.00e-110	392.00
IUUC-Ete-032372	Echinops telfairi	76.79	0.00e+00	1670.00
IUUC-Eca-033896	Equus caballus	92.97	0.00e+00	2137.00
IUUC-Eeu-035099	Erinaceus europaeus	84.62	0.00e+00	1197.00
IUUC-Fca-035616	Felis catus	89.89	0.00e+00	1991.00
IUUC-Fal-037231	Ficedula albicollis	74.31	0.00e+00	1629.00
IUUC-Gmo-039439	Gadus morhua	74.52	0.00e+00	679.00
IUUC-Gac-041516	Gasterosteus aculeatus	67.43	0.00e+00	1498.00
IUUC-Hsa-046674	Homo sapiens	92.10	0.00e+00	2106.00
IUUC-Itr-048879	Ictidomys tridecemlineatus	91.79	0.00e+00	2079.00
IUUC-Lch-049689	Latimeria chalumnae	70.22	0.00e+00	1620.00
IUUC-Loc-052417	Lepisosteus oculatus	51.75	2.00e-130	459.00
IUUC-Laf-053795	Loxodonta africana	89.90	0.00e+00	2044.00
IUUC-Mcc-055502	Macaca mulatta	92.73	0.00e+00	2102.00
IUUC-Mga-059805	Meleagris gallopavo	77.61	0.00e+00	1711.00
IUUC-Mmr-060997	Microcebus murinus	91.56	0.00e+00	2103.00
IUUC-Mdo-062940	Monodelphis domestica	80.23	0.00e+00	1798.00
IUUC-Mmu-063255	Mus musculus	90.23	0.00e+00	2037.00
IUUC-Mpu-066158	Mustela putorius furo	95.70	0.00e+00	2170.00
IUUC-Mlu-067201	Myotis lucifugus	87.86	0.00e+00	2008.00
IUUC-Nle-069145	Nomascus leucogenys	94.13	0.00e+00	1331.00
IUUC-Opr-070797	Ochotona princeps	86.32	0.00e+00	1912.00
IUUC-Ont-071553	Oreochromis niloticus	67.23	0.00e+00	1500.00
IUUC-Ocu-074598	Oryctolagus cuniculus	91.95	0.00e+00	2043.00
IUUC-Ola-086650	Oryzias latipes	84.68	8.00e-113	399.00
IUUC-Oar-089287	Ovis aries	87.24	0.00e+00	1122.00
IUUC-Pan-092004	Papio anubis	92.51	0.00e+00	2078.00
IUUC-Psi-093028	Pelodiscus sinensis	71.53	0.00e+00	1506.00
IUUC-Pma-094145	Petromyzon marinus	61.07	0.00e+00	748.00
IUUC-Pfo-096320	Poecilia formosa	66.82	0.00e+00	1508.00
IUUC-Pab-097862	Pongo abelii	92.57	0.00e+00	2111.00
IUUC-Pca-100862	Procavia capensis	77.71	0.00e+00	1625.00
IUUC-Pva-103050	Pteropus vampyrus	92.11	0.00e+00	1318.00
IUUC-Rno-105852	Rattus norvegicus	90.62	0.00e+00	2054.00
IUUC-Sha-107312	Sarcophilus harrisii	80.62	0.00e+00	1813.00
IUUC-Sar-113311	Sorex araneus	86.28	0.00e+00	788.00
IUUC-Ssc-116356	Sus scrofa	92.50	0.00e+00	2133.00
IUUC-Tgu-116896	Taeniopygia guttata	60.50	2.00e-145	510.00
IUUC-Tru-118197	Takifugu rubripes	67.76	0.00e+00	1508.00
IUUC-Tni-119823	Tetraodon nigroviridis	65.24	0.00e+00	1490.00
IUUC-Ttr-129164	Tursiops truncatus	92.58	0.00e+00	2058.00
IUUC-Xtr-132819	Xenopus tropicalis	68.67	0.00e+00	1606.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence