iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-005342

Ensembl Protein ID

ENSACAP00000021897.1

UniProt Accession

R4G9J4; R4G9J4_ANOCA

Protein Name

Uncharacterized protein

Gene Name

LOC103278896

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000028775.1	ENSACAT00000029315.1	ENSACAP00000021897.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	4.10e-77	259.8	731	1053

Active Site

Position(s)	Description	Evidence
1021	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 7    krlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlpls 93
           + ++v+f+gE g+d gG+++ef++ l+kel+ p+  +f++ ++++  ++p +      p + +++ ++G l g+al+++++   p++
   Q: 731  QFFKVQFEGEPGIDDGGLSQEFFTILVKELCAPKCRIFTHFDESHLIWFPPQV-----PAQKDIYFLIGNLFGMALYNQKIAAFPFP 812
           3456**************************************99999998764.....46778899********************* PP
   S: 94   ksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvvey 180
            +++k++ +++ +ledl+e+ p++ +sl+ +++ + +d+ el l+l f + ee+ g+++  eLk++G+n pVt++N++eYv+++v+y
   Q: 813  LALFKKMANVQPTLEDLKELFPTIGRSLQTVLDEQREDVIEL-LQLDFMKVEEHEGSRTMIELKENGANLPVTKSNRKEYVDAYVHY 898
           **********************************99999998.9****99999********************************** PP
   S: 181  rlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqF 267
           ++++++++q++ f +Gf++ +p  + ++F++ el+l++ G +++d+e+++k++ky g y+++++ i+ Fw+ ++++ +e +k+fL F
   Q: 899  IFTTSVEKQFADFMRGFERGCPTGKWKIFNPIELQLVLLGHKKYDWEQFEKNAKYAG-YEKTEQIIKDFWDEFHDLPEEMKKDFLAF 984
           *******************************************************55.***************************** PP
   S: 268  vTgssrlPlgGfaelkprlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           +Tg++r+P++G++++   ++  rk+  d ++P+++TC   L LP+Ys+ ++lk++ l+A e+++ F+ls
   Q: 985  LTGTNRIPAQGMEKFIFTITDSRKEDPDLWYPEASTCCKILFLPRYSNRDVLKKMFLTALEYSEKFGLS 1053
           ****************777777778899**************************************985 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MPAGKKQPAK MPKREKMRRC PKEMPKKRET LGKGKAPSQS GPPPTPSSGK SMGLRLFPER 60
DQVCRVDPGA IRQISCKHGY LAVVGTQKRD VLVFEPAAGK PGCPNAARRK PKHIKLKKNS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATACCATAC TTTCCTTTTT TACGTTTCTA TGAAGCAATT GGGGCCAGTT AACACCTCCT 60
AACAAAGGAC TCCCCCCAGG CAGGAAGCAG CCAGGCTTTG AAGCTGAAAG GCAATTCAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens

PROSITE

PS50237--HECT
PS00626--RCC1_2
PS50012--RCC1_3

Pfam

PF00632--HECT
PF00415--RCC1

PRINTS

PR00633--RCCNDNSATION

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

acs:103278896

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-012422	Bos taurus	36.57	1.00e-158	553.00
IUUC-Dor-030862	Dipodomys ordii	39.45	2.00e-99	357.00
IUUC-Fal-037529	Ficedula albicollis	47.47	0.00e+00	805.00
IUUC-Gga-041079	Gallus gallus	46.74	0.00e+00	775.00
IUUC-Loc-052283	Lepisosteus oculatus	40.94	0.00e+00	657.00
IUUC-Mga-059605	Meleagris gallopavo	45.31	0.00e+00	657.00
IUUC-Sar-113605	Sorex araneus	50.48	2.00e-85	310.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence