iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000017788.1	ENSSHAT00000021147.1	ENSSHAP00000020977.1
ENSSHAG00000017788.1	ENSSHAT00000021148.1	ENSSHAP00000020978.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-30	103.9	118	156
UBD/Beta-Prp	1.20e-54	185.7	221	478

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvllk 37
           gH +sv+c+af  s++++ +GsdD+ +k+W++++g+ll 
   Q: 118  GHLSSVYCVAFdrSGRRIFTGSDDCLVKIWSTDDGRLLS 156
           8**********96669*******************9875 PP

UBD/Beta-Prp

   S: 23   sllatgsrdgtikvwdvttgkl......lrslsgheae..........vtavkfspdgkilvtgseDrtikvw..dlstgkcvhtlkgh 93
           ++l+++++dgti  w+++  ++      l        +          +++ +fs+ g ++vtgs+D++i+++    ++++ +  l+ h
   Q: 221  RYLTSTGADGTICFWQWHVNTMkfkdrpL--------KftersrpgvqISCSSFSSGGMFIVTGSTDHVIRIYylGSESPEKIAELESH 301
           799***********999886665566652........2333334456699***********************88888*********** PP
   S: 94   edsvlslsfspsg..dklvsGshdrtirvwdletgqclee...............tlsghdgvvncvvvhpdgnllvsGslDrtvrlWd 165
           +d+v++++f+ +g   k+vsGs+d t+++w+ +++++ +                 +++ +  v++v+++  +  ++++ ++  +++W+
   Q: 302  TDKVVAVQFCNNGdsLKFVSGSRDGTAKIWQYQQQEWKKMvldmttkatghnlpnEDKVSKLKVTMVAWDRYDATVITAVNNFLLKVWN 390
           ***********7733589*******************999*************9999999999************************** PP
   S: 166  lktgkllrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsi 246
           ++tg+ll+ ltg h+d v  l+   fd+  + ++s+++dg v +wdl +g+ +r + +         v + +fsp++++++++ s+g +
   Q: 391  SSTGQLLHNLTG-HDDEVFVLEahpFDQ--RIMLSAGHDGNVFIWDLDRGTKIRNYFNMIegqghGAVFDCKFSPDGQHFACTDSHGHL 476
           ***********9.*********555555..999*******************9888775545555777788999999999999998877 PP
   S: 247  ri 248
            +
   Q: 477  LL 478
           66 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

VTANAHIPPD YLLKICERIG PLLDREIPQS VPGVQTLLGV GRQSLLRAAK GKTCLAFGGD 60
GQMGKDCGRP PELPADYTRA PNVVTITSAR QLTGCGRFSH IFPSSSYQQM KMHKRILGHL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTAAAGGT TTTGCTCACT ATCAAACATT TGTGTGTTGT ATTGTTGCTG TTTTAGGTGA 60
CAGCCAATGC ACACATTCCT CCAGACTACC TCCTTAAAAT TTGTGAGCGG ATTGGTCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR002469--Peptidase_S9B_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001881	Ailuropoda melanoleuca	75.98	0.00e+00	2341.00
IUUC-Apl-004016	Anas platyrhynchos	74.53	0.00e+00	2092.00
IUUC-Aca-004722	Anolis carolinensis	73.60	0.00e+00	2081.00
IUUC-Ame-010602	Astyanax mexicanus	62.88	0.00e+00	1730.00
IUUC-Bta-013198	Bos taurus	75.83	0.00e+00	2227.00
IUUC-Cja-019966	Callithrix jacchus	58.92	0.00e+00	1649.00
IUUC-Cfa-020963	Canis familiaris	76.60	0.00e+00	2332.00
IUUC-Cpo-022448	Cavia porcellus	72.20	0.00e+00	2206.00
IUUC-Csa-023166	Chlorocebus sabaeus	76.57	0.00e+00	2322.00
IUUC-Cin-025553	Ciona intestinalis	39.63	9.00e-112	397.00
IUUC-Dre-028508	Danio rerio	63.40	0.00e+00	1691.00
IUUC-Dno-030070	Dasypus novemcinctus	75.65	0.00e+00	2215.00
IUUC-Dor-031052	Dipodomys ordii	72.27	0.00e+00	980.00
IUUC-Ete-032650	Echinops telfairi	76.64	0.00e+00	1481.00
IUUC-Eca-033953	Equus caballus	77.20	0.00e+00	2202.00
IUUC-Eeu-034871	Erinaceus europaeus	68.25	0.00e+00	1031.00
IUUC-Fca-036099	Felis catus	76.35	0.00e+00	2339.00
IUUC-Fal-037246	Ficedula albicollis	76.80	0.00e+00	2268.00
IUUC-Gga-041097	Gallus gallus	77.52	0.00e+00	2298.00
IUUC-Gac-042435	Gasterosteus aculeatus	62.62	0.00e+00	1699.00
IUUC-Ggo-045500	Gorilla gorilla	59.00	0.00e+00	1633.00
IUUC-Hsa-045666	Homo sapiens	76.70	0.00e+00	2331.00
IUUC-Lch-050646	Latimeria chalumnae	58.10	0.00e+00	1654.00
IUUC-Loc-051802	Lepisosteus oculatus	66.60	0.00e+00	1912.00
IUUC-Laf-053942	Loxodonta africana	77.25	0.00e+00	2331.00
IUUC-Mcc-054645	Macaca mulatta	76.70	0.00e+00	2327.00
IUUC-Meu-056321	Macropus eugenii	79.80	0.00e+00	1132.00
IUUC-Mga-060063	Meleagris gallopavo	77.67	0.00e+00	2308.00
IUUC-Mmr-061262	Microcebus murinus	77.57	0.00e+00	2327.00
IUUC-Mdo-062320	Monodelphis domestica	80.61	0.00e+00	2564.00
IUUC-Mmu-063163	Mus musculus	77.43	0.00e+00	2261.00
IUUC-Mpu-066628	Mustela putorius furo	76.10	0.00e+00	2337.00
IUUC-Mlu-068082	Myotis lucifugus	76.26	0.00e+00	2296.00
IUUC-Nle-069609	Nomascus leucogenys	76.82	0.00e+00	2348.00
IUUC-Ont-071589	Oreochromis niloticus	63.49	0.00e+00	1674.00
IUUC-Ocu-074122	Oryctolagus cuniculus	77.02	0.00e+00	1740.00
IUUC-Ola-086580	Oryzias latipes	64.03	0.00e+00	1731.00
IUUC-Oga-089053	Otolemur garnettii	77.70	0.00e+00	2308.00
IUUC-Oar-090042	Ovis aries	75.77	0.00e+00	2327.00
IUUC-Ptr-091268	Pan troglodytes	76.70	0.00e+00	2330.00
IUUC-Pan-092376	Papio anubis	76.70	0.00e+00	2327.00
IUUC-Psi-093408	Pelodiscus sinensis	76.70	0.00e+00	2363.00
IUUC-Pfo-096515	Poecilia formosa	63.47	0.00e+00	1622.00
IUUC-Pab-097672	Pongo abelii	75.83	0.00e+00	2316.00
IUUC-Pva-102512	Pteropus vampyrus	82.76	0.00e+00	1936.00
IUUC-Rno-105797	Rattus norvegicus	76.71	0.00e+00	2264.00
IUUC-Sar-113004	Sorex araneus	61.71	0.00e+00	1135.00
IUUC-Tgu-117254	Taeniopygia guttata	76.87	0.00e+00	2270.00
IUUC-Tru-118186	Takifugu rubripes	62.70	0.00e+00	1678.00
IUUC-Tsy-119003	Tarsius syrichta	72.58	0.00e+00	2094.00
IUUC-Tni-120110	Tetraodon nigroviridis	62.77	0.00e+00	1662.00
IUUC-Ttr-129265	Tursiops truncatus	78.43	0.00e+00	2251.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence