iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-091274

Ensembl Protein ID

ENSPTRP00000057514.2

UniProt Accession

H2RCM1; H2RCM1_PANTR

Genbank Protein ID

JAA07129.1; JAA15882.1; JAA30210.1; JAA40799.1

Protein Name

Zinc finger and BTB domain containing 1

Genbank Nucleotide ID

AACZ03095231; GABF01006263; GABD01002890; GABE01003940

Gene Name

ZBTB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000006438.5	ENSPTRT00000065940.2	ENSPTRP00000057514.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	6.90e-13	48.8	24	87

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalf.lmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +D+++ +++ +f+ahk+vLaa+Ss+F+  f +++ +  +  +  ++k +++e+f  +l+F+Y gk+
   Q: 24   CDCCIAIDDIYFQAHKAVLAACSSYFRMFFmNHQHSTAQ-LNLSNMK-ISAECFDLILQFMYLGKI 87
           8*************************9999333333333.5555666.****************97 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MAKPSHSSYV LQQLNNQREW GFLCDCCIAI DDIYFQAHKA VLAACSSYFR MFFMNHQHST 60
AQLNLSNMKI SAECFDLILQ FMYLGKIMTA PSSFEQFKVA MNYLQLYNVP DCLEDIQDAD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCAGAAACT TGTTGCAACA AACAGGCGAC CGCGGGTGCC CCTAGCAGCC AGCGGCAGAG 60
TGGGTGGGCG GGCGAGAGGG AGGGGAAGGC TGGCGGACGC CGCAGCGAAC TGGTGGGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000210--BTB/POZ_dom
IPR000877--Prot_inh_BBI
IPR004039--Rubredoxin-type_fold
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0016604--C:nuclear body
GO:0031965--C:nuclear membrane
GO:0046872--F:metal ion binding
GO:0003676--F:nucleic acid binding
GO:0030183--P:B cell differentiation
GO:0034644--P:cellular response to UV
GO:0006338--P:chromatin remodeling
GO:0042789--P:mRNA transcription from RNA polymerase II promoter
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0032825--P:positive regulation of natural killer cell differentiation
GO:2000176--P:positive regulation of pro-T cell differentiation
GO:0002711--P:positive regulation of T cell mediated immunity
GO:0051260--P:protein homooligomerization
GO:0033077--P:T cell differentiation in thymus
GO:0048538--P:thymus development
GO:0019985--P:translesion synthesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001844	Ailuropoda melanoleuca	97.05	0.00e+00	1352.00
IUUC-Apl-003725	Anas platyrhynchos	82.27	0.00e+00	1134.00
IUUC-Aca-004672	Anolis carolinensis	71.78	0.00e+00	952.00
IUUC-Ame-011859	Astyanax mexicanus	48.57	3.00e-179	622.00
IUUC-Bta-013323	Bos taurus	98.04	0.00e+00	1414.00
IUUC-Cja-018727	Callithrix jacchus	99.02	0.00e+00	1375.00
IUUC-Cfa-020390	Canis familiaris	97.05	0.00e+00	1360.00
IUUC-Cpo-022434	Cavia porcellus	96.35	0.00e+00	1385.00
IUUC-Csa-023909	Chlorocebus sabaeus	98.89	0.00e+00	1181.00
IUUC-Cho-024288	Choloepus hoffmanni	96.88	0.00e+00	954.00
IUUC-Dre-027623	Danio rerio	47.62	2.00e-179	622.00
IUUC-Dno-029224	Dasypus novemcinctus	98.04	0.00e+00	1412.00
IUUC-Ete-032672	Echinops telfairi	93.24	0.00e+00	989.00
IUUC-Eca-034361	Equus caballus	97.94	0.00e+00	1194.00
IUUC-Eeu-035254	Erinaceus europaeus	90.58	4.00e-157	548.00
IUUC-Fca-036217	Felis catus	96.77	0.00e+00	1394.00
IUUC-Fal-037026	Ficedula albicollis	78.16	0.00e+00	958.00
IUUC-Gga-040550	Gallus gallus	77.08	9.00e-143	499.00
IUUC-Gac-041379	Gasterosteus aculeatus	45.93	7.00e-170	590.00
IUUC-Ggo-044852	Gorilla gorilla	99.86	0.00e+00	1432.00
IUUC-Hsa-046418	Homo sapiens	100.00	0.00e+00	1434.00
IUUC-Itr-048065	Ictidomys tridecemlineatus	97.19	0.00e+00	1395.00
IUUC-Lch-050025	Latimeria chalumnae	55.92	0.00e+00	786.00
IUUC-Loc-052590	Lepisosteus oculatus	50.41	0.00e+00	653.00
IUUC-Laf-054526	Loxodonta africana	96.77	0.00e+00	1377.00
IUUC-Mcc-055796	Macaca mulatta	99.02	0.00e+00	1355.00
IUUC-Mga-059889	Meleagris gallopavo	81.58	0.00e+00	1145.00
IUUC-Mmr-061304	Microcebus murinus	98.04	0.00e+00	1365.00
IUUC-Mdo-062964	Monodelphis domestica	89.06	0.00e+00	1279.00
IUUC-Mmu-064268	Mus musculus	94.96	0.00e+00	1355.00
IUUC-Mpu-065817	Mustela putorius furo	95.57	0.00e+00	1169.00
IUUC-Mlu-068225	Myotis lucifugus	97.48	0.00e+00	1380.00
IUUC-Nle-069390	Nomascus leucogenys	99.44	0.00e+00	1424.00
IUUC-Opr-070274	Ochotona princeps	95.79	0.00e+00	1338.00
IUUC-Ont-072145	Oreochromis niloticus	46.26	6.00e-172	597.00
IUUC-Oan-073144	Ornithorhynchus anatinus	84.91	0.00e+00	1026.00
IUUC-Ocu-074835	Oryctolagus cuniculus	89.90	0.00e+00	1240.00
IUUC-Ola-087520	Oryzias latipes	46.92	3.00e-170	592.00
IUUC-Oga-088605	Otolemur garnettii	97.34	0.00e+00	1395.00
IUUC-Oar-089788	Ovis aries	98.04	0.00e+00	1414.00
IUUC-Psi-093560	Pelodiscus sinensis	79.97	0.00e+00	1010.00
IUUC-Pfo-097221	Poecilia formosa	46.70	8.00e-169	587.00
IUUC-Pab-097799	Pongo abelii	99.53	0.00e+00	1254.00
IUUC-Pva-102769	Pteropus vampyrus	97.48	0.00e+00	1363.00
IUUC-Rno-105959	Rattus norvegicus	92.10	0.00e+00	1166.00
IUUC-Sha-106613	Sarcophilus harrisii	88.64	0.00e+00	1265.00
IUUC-Sar-112951	Sorex araneus	86.39	0.00e+00	1082.00
IUUC-Ssc-115673	Sus scrofa	97.76	0.00e+00	1361.00
IUUC-Tgu-116806	Taeniopygia guttata	80.19	0.00e+00	1103.00
IUUC-Tru-117544	Takifugu rubripes	43.21	3.00e-132	465.00
IUUC-Tsy-119233	Tarsius syrichta	90.88	0.00e+00	1241.00
IUUC-Tni-120273	Tetraodon nigroviridis	57.05	5.00e-101	361.00
IUUC-Tbe-128020	Tupaia belangeri	96.76	0.00e+00	1194.00
IUUC-Ttr-128357	Tursiops truncatus	97.76	0.00e+00	1350.00
IUUC-Vpa-130487	Vicugna pacos	98.04	0.00e+00	1413.00
IUUC-Xtr-132415	Xenopus tropicalis	58.08	0.00e+00	796.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence