iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052895

Ensembl Protein ID

ENSLOCP00000019030.1

UniProt Accession

W5NEH1; W5NEH1_LEPOC

Genbank Protein ID

ENSLOCP00000019030

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01027896

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000015464.1	ENSLOCT00000019062.1	ENSLOCP00000019030.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-37	126.2	412	444
UBD/Beta-Prp	7.30e-63	212.7	169	456

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           gHtd +t+l+f +d  l++s+s D++++vWD+r
   Q: 412  GHTDTITSLSFsPDsSLVASSSMDNSVRVWDIR 444
           8***********9999***************86 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkl................................lrslsgheaevtavkfspd 63
           +h ++ ++   +s d++lla+g++++++k+w+++   l                                ++ l gh ++v+ + f  d
   Q: 169  HHTEQLLNTAEISGDSKLLAAGFDSSCVKLWSLRARRLraqphvvdvsrvhlacdvldeeaddedsagseMKILRGHCGPVYRTAFLTD 257
           566667777888***************************************************************************** PP
   S: 64   gkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnll 152
           ++ l+t+seD ti+ wdl +++ +  ++gh + v+++++sp + +++s shdrt+r+w     + l+ + +gh + v cv++hp++++l
   Q: 258  SSGLITCSEDTTIRYWDLGSFTNTALYQGHAYPVWDVDISPCSLYFASSSHDRTARLWTFGRTYPLR-LYAGHLADVDCVKFHPNSSYL 345
           *******************************************************************.********************* PP
   S: 153  vsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgs 241
           ++Gs+D+tvrlW+l++g+ +r +tg h ++v  l+f++ngk+l+s+++d+++klwdl +g+  + l+ghtd+++s+ fsp++ +++s s
   Q: 346  ATGSTDKTVRLWSLQQGNSVRLFTG-HRGPVLALAFSPNGKYLASAGEDQRLKLWDLASGTLFKDLRGHTDTITSLSFSPDSSLVASSS 433
           ************************9.*************************************************************** PP
   S: 242  sDgsiriWdlrsgdllktlqlhn 264
           +D+s+r+Wd+r+  +     ++ 
   Q: 434  MDNSVRVWDIRNAYCSAPADGSS 456
           ********999988876666655 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MKRVRAEQIQ YTVAQYLKRR QYVDVESSLK GAKLSQTAEE MAANLTVQTE SGCANVVSAA 60
PCQADPQQYE LQFGQLHSFL SGKLNVISEL RPHADSLKGS VSSWCQRNRP FSFQQLLKDG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCATAACTAT AAACTAGTAT AATAAATAAG AATAATTTCA GTAGATACCG ATTACCTGTG 60
TACAAATATA TGACCATTTA ATGTATTTTT ACACATAAAA CAGAAACTGT AGTTTACAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002016	Ailuropoda melanoleuca	83.38	0.00e+00	630.00
IUUC-Apl-003636	Anas platyrhynchos	83.56	0.00e+00	661.00
IUUC-Aca-004229	Anolis carolinensis	79.49	0.00e+00	637.00
IUUC-Ame-010599	Astyanax mexicanus	80.65	5.00e-175	607.00
IUUC-Bta-013404	Bos taurus	81.74	3.00e-176	611.00
IUUC-Cja-019643	Callithrix jacchus	82.48	0.00e+00	632.00
IUUC-Cfa-020913	Canis familiaris	82.53	0.00e+00	633.00
IUUC-Cpo-021777	Cavia porcellus	81.47	9.00e-177	613.00
IUUC-Csa-024184	Chlorocebus sabaeus	82.21	0.00e+00	643.00
IUUC-Cho-024638	Choloepus hoffmanni	83.47	0.00e+00	638.00
IUUC-Cin-025618	Ciona intestinalis	43.52	1.00e-72	267.00
IUUC-Csv-025874	Ciona savignyi	41.23	8.00e-75	274.00
IUUC-Dre-028817	Danio rerio	81.57	7.00e-174	603.00
IUUC-Dno-029969	Dasypus novemcinctus	67.71	0.00e+00	630.00
IUUC-Dor-031117	Dipodomys ordii	83.11	0.00e+00	644.00
IUUC-Ete-032712	Echinops telfairi	82.29	2.00e-180	625.00
IUUC-Eca-033742	Equus caballus	82.75	0.00e+00	632.00
IUUC-Eeu-035096	Erinaceus europaeus	82.35	0.00e+00	650.00
IUUC-Fca-035769	Felis catus	83.33	0.00e+00	660.00
IUUC-Fal-036645	Ficedula albicollis	82.60	6.00e-174	603.00
IUUC-Gmo-038636	Gadus morhua	74.39	2.00e-158	552.00
IUUC-Gga-040144	Gallus gallus	83.06	0.00e+00	639.00
IUUC-Gac-041716	Gasterosteus aculeatus	84.03	2.00e-172	598.00
IUUC-Ggo-044568	Gorilla gorilla	82.48	0.00e+00	632.00
IUUC-Hsa-046178	Homo sapiens	82.48	0.00e+00	632.00
IUUC-Itr-048967	Ictidomys tridecemlineatus	78.22	1.00e-178	619.00
IUUC-Lch-050501	Latimeria chalumnae	79.07	5.00e-164	570.00
IUUC-Laf-053950	Loxodonta africana	80.11	2.00e-177	615.00
IUUC-Mcc-055450	Macaca mulatta	82.21	0.00e+00	628.00
IUUC-Meu-056182	Macropus eugenii	83.47	0.00e+00	633.00
IUUC-Mga-059619	Meleagris gallopavo	83.33	0.00e+00	642.00
IUUC-Mmr-061074	Microcebus murinus	83.33	0.00e+00	636.00
IUUC-Mdo-062307	Monodelphis domestica	82.17	1.00e-123	437.00
IUUC-Mmu-063226	Mus musculus	78.59	9.00e-175	606.00
IUUC-Mpu-066016	Mustela putorius furo	82.83	1.00e-180	625.00
IUUC-Mlu-067257	Myotis lucifugus	79.89	5.00e-179	620.00
IUUC-Nle-070139	Nomascus leucogenys	82.48	0.00e+00	632.00
IUUC-Opr-070243	Ochotona princeps	82.61	0.00e+00	640.00
IUUC-Ont-072686	Oreochromis niloticus	83.16	5.00e-179	620.00
IUUC-Oan-073670	Ornithorhynchus anatinus	68.41	5.00e-176	610.00
IUUC-Ocu-074525	Oryctolagus cuniculus	83.42	0.00e+00	634.00
IUUC-Ola-086524	Oryzias latipes	83.01	0.00e+00	644.00
IUUC-Oga-088540	Otolemur garnettii	80.89	0.00e+00	627.00
IUUC-Oar-089793	Ovis aries	77.66	5.00e-159	554.00
IUUC-Ptr-091154	Pan troglodytes	82.48	0.00e+00	632.00
IUUC-Pan-092759	Papio anubis	82.21	0.00e+00	628.00
IUUC-Psi-094008	Pelodiscus sinensis	79.57	2.00e-178	619.00
IUUC-Pma-094593	Petromyzon marinus	56.90	2.00e-109	389.00
IUUC-Pfo-097409	Poecilia formosa	81.84	2.00e-171	595.00
IUUC-Pab-097946	Pongo abelii	68.79	0.00e+00	674.00
IUUC-Pca-100727	Procavia capensis	82.56	0.00e+00	626.00
IUUC-Pva-103211	Pteropus vampyrus	78.51	4.00e-172	598.00
IUUC-Rno-105236	Rattus norvegicus	81.47	1.00e-176	613.00
IUUC-Sha-106833	Sarcophilus harrisii	81.94	3.00e-178	618.00
IUUC-Sar-113381	Sorex araneus	83.78	0.00e+00	661.00
IUUC-Ssc-116421	Sus scrofa	82.83	0.00e+00	649.00
IUUC-Tgu-117143	Taeniopygia guttata	82.75	0.00e+00	657.00
IUUC-Tru-118680	Takifugu rubripes	83.19	1.00e-179	623.00
IUUC-Tsy-119622	Tarsius syrichta	69.57	1.00e-140	493.00
IUUC-Tni-120131	Tetraodon nigroviridis	83.47	0.00e+00	628.00
IUUC-Ttr-129171	Tursiops truncatus	82.42	0.00e+00	631.00
IUUC-Xtr-132241	Xenopus tropicalis	78.88	2.00e-176	612.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence