iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-097946

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01197727

Gene Name

TAF5L

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000000124.2	ENSPPYT00000000135.2	ENSPPYP00000000126.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.30e-42	140.4	438	470
UBD/Beta-Prp	4.60e-68	229.7	201	494

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           gHtd +t+l f +d +l++s+s D++++vWD+r
   Q: 438  GHTDNITSLTFsPDsGLIASASMDNSVRVWDIR 470
           8***********999****************76 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkl................................lrslsgheaevtavkfspdgkilvt 69
           ++   +spd++lla+g+++++ik+w+++++kl                                ++ l gh ++v++++f  d++ l++
   Q: 201  LNTAEISPDSKLLAAGFDNSCIKLWSLRSKKLksephqvdvsrihlacdileeeddeddnagteMKILRGHCGPVYSTRFLADSSGLLS 289
           5667889********************************************************************************** PP
   S: 70   gseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslD 158
           +seD+ i+ wdl +++ ++ ++gh + v++l++sp++ +++sGshdrt+r+w  +  + l+ + +gh + v cv++hp++n+l++Gs+D
   Q: 290  CSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLR-IYAGHLADVDCVKFHPNSNYLATGSTD 377
           *************************************************************.*************************** PP
   S: 159  rtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsir 247
           +tvrlW+ ++g+ +r +tg h ++v sl+f++ngk+l+s+++d+++klwdl +g+  ++l+ghtdn++s+ fsp++ +++s+s+D+s+r
   Q: 378  KTVRLWSAQQGNSVRLFTG-HRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVR 465
           ******************9.********************************************************************* PP
   S: 248  iWdlrsgdllktlqlhnssvisvavlsfg 276
           +Wd+r+  +     ++ s ++ v + +++
   Q: 466  VWDIRNTYCSAPADGSSSELVGVYTGQMS 494
           **999999988888888666666663333 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MKRVRTEQIQ MAVSCYLKRR QYVDSDGPLK QGLRLSQTAE EMAANLTDSD SQHSHEVMPL 60
LYPLFVYLQL QTTNPIQDIL SNFKLRAFLD NKYVVRLQED SYNYLIRYLQ SDNNTALCKV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAACGAG TGCGTACCGA GCAGATTCAG ATGGCAGTGT CCTGCTACCT CAAACGCCGG 60
CAGTACGTGG ACTCAGATGG TCCCCTGAAG CAAGGACTGC GGCTGTCACA GACTGCTGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR007582--TFIID_NTD2
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04494--TFIID_NTD2
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016607--C:nuclear speck
GO:0000932--C:P-body
GO:0030914--C:STAGA complex
GO:0033276--C:transcription factor TFTC complex
GO:0004402--F:histone acetyltransferase activity
GO:0003713--F:transcription coactivator activity
GO:0043966--P:histone H3 acetylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002016	Ailuropoda melanoleuca	84.89	0.00e+00	936.00
IUUC-Apl-003636	Anas platyrhynchos	81.90	0.00e+00	962.00
IUUC-Aca-004229	Anolis carolinensis	81.66	0.00e+00	936.00
IUUC-Ame-010599	Astyanax mexicanus	60.73	0.00e+00	696.00
IUUC-Bta-013404	Bos taurus	79.97	0.00e+00	881.00
IUUC-Cja-019643	Callithrix jacchus	86.25	0.00e+00	972.00
IUUC-Cfa-020913	Canis familiaris	85.40	0.00e+00	959.00
IUUC-Cpo-021777	Cavia porcellus	81.83	0.00e+00	911.00
IUUC-Csa-024184	Chlorocebus sabaeus	86.25	0.00e+00	975.00
IUUC-Cho-024638	Choloepus hoffmanni	84.72	0.00e+00	931.00
IUUC-Cin-025618	Ciona intestinalis	33.67	2.00e-80	293.00
IUUC-Csv-025874	Ciona savignyi	42.31	2.00e-77	283.00
IUUC-Dre-028817	Danio rerio	60.47	0.00e+00	685.00
IUUC-Dno-029969	Dasypus novemcinctus	77.42	0.00e+00	897.00
IUUC-Dor-031117	Dipodomys ordii	83.19	0.00e+00	950.00
IUUC-Ete-032712	Echinops telfairi	82.34	0.00e+00	906.00
IUUC-Eca-033742	Equus caballus	85.40	0.00e+00	960.00
IUUC-Eeu-035096	Erinaceus europaeus	82.37	0.00e+00	961.00
IUUC-Fca-035769	Felis catus	84.43	0.00e+00	981.00
IUUC-Fal-036645	Ficedula albicollis	80.76	0.00e+00	893.00
IUUC-Fso-038302	Fusarium solani	33.24	2.00e-40	160.00
IUUC-Gmo-038636	Gadus morhua	57.50	0.00e+00	644.00
IUUC-Gga-040144	Gallus gallus	81.83	0.00e+00	932.00
IUUC-Gac-041716	Gasterosteus aculeatus	60.20	0.00e+00	674.00
IUUC-Ggo-044568	Gorilla gorilla	86.42	0.00e+00	973.00
IUUC-Hsa-046178	Homo sapiens	86.42	0.00e+00	973.00
IUUC-Itr-048967	Ictidomys tridecemlineatus	78.95	0.00e+00	917.00
IUUC-Lch-050501	Latimeria chalumnae	71.63	0.00e+00	775.00
IUUC-Loc-052895	Lepisosteus oculatus	68.45	0.00e+00	688.00
IUUC-Laf-053950	Loxodonta africana	80.98	0.00e+00	899.00
IUUC-Mcc-055450	Macaca mulatta	86.25	0.00e+00	969.00
IUUC-Meu-056182	Macropus eugenii	84.04	0.00e+00	938.00
IUUC-Mga-059619	Meleagris gallopavo	82.00	0.00e+00	935.00
IUUC-Mmr-061074	Microcebus murinus	85.96	0.00e+00	978.00
IUUC-Mdo-062307	Monodelphis domestica	80.62	0.00e+00	729.00
IUUC-Mmu-063226	Mus musculus	80.48	0.00e+00	905.00
IUUC-Mpu-066016	Mustela putorius furo	84.72	0.00e+00	931.00
IUUC-Mlu-067257	Myotis lucifugus	77.46	0.00e+00	908.00
IUUC-Nle-070139	Nomascus leucogenys	86.42	0.00e+00	973.00
IUUC-Opr-070243	Ochotona princeps	82.34	0.00e+00	923.00
IUUC-Ont-072686	Oreochromis niloticus	62.40	0.00e+00	707.00
IUUC-Oan-073670	Ornithorhynchus anatinus	77.06	0.00e+00	766.00
IUUC-Ocu-074525	Oryctolagus cuniculus	86.59	0.00e+00	964.00
IUUC-Ola-086524	Oryzias latipes	61.90	0.00e+00	724.00
IUUC-Oga-088540	Otolemur garnettii	84.89	0.00e+00	957.00
IUUC-Oar-089793	Ovis aries	77.03	0.00e+00	814.00
IUUC-Ptr-091154	Pan troglodytes	86.42	0.00e+00	973.00
IUUC-Pan-092759	Papio anubis	86.25	0.00e+00	969.00
IUUC-Psi-094008	Pelodiscus sinensis	79.29	0.00e+00	926.00
IUUC-Pma-094593	Petromyzon marinus	49.56	7.00e-116	410.00
IUUC-Pfo-097409	Poecilia formosa	59.90	0.00e+00	679.00
IUUC-Pca-100727	Procavia capensis	82.68	0.00e+00	914.00
IUUC-Pva-103211	Pteropus vampyrus	74.19	0.00e+00	847.00
IUUC-Ptt-103995	Puccinia triticina	43.83	5.00e-70	259.00
IUUC-Rno-105236	Rattus norvegicus	80.81	0.00e+00	895.00
IUUC-Sha-106833	Sarcophilus harrisii	82.94	0.00e+00	923.00
IUUC-Sar-113381	Sorex araneus	85.23	0.00e+00	989.00
IUUC-Ssc-116421	Sus scrofa	83.36	0.00e+00	959.00
IUUC-Tgu-117143	Taeniopygia guttata	82.34	0.00e+00	964.00
IUUC-Tru-118680	Takifugu rubripes	61.33	0.00e+00	704.00
IUUC-Tsy-119622	Tarsius syrichta	75.38	0.00e+00	776.00
IUUC-Tni-120131	Tetraodon nigroviridis	60.07	0.00e+00	700.00
IUUC-Tbe-127656	Tupaia belangeri	95.45	5.00e-89	321.00
IUUC-Ttr-129171	Tursiops truncatus	81.49	0.00e+00	903.00
IUUC-Xtr-132241	Xenopus tropicalis	73.56	0.00e+00	827.00
IUUC-Xma-133554	Xiphophorus maculatus	59.36	5.00e-177	613.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence