iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cja-019845

Ensembl Protein ID

ENSCJAP00000024139.2

UniProt Accession

F7DRF8; F7DRF8_CALJA

Genbank Protein ID

JAB02847.1; JAB17748.1; JAB31730.1

Protein Name

Guanine nucleotide-binding protein subunit beta-4

Genbank Nucleotide ID

ACFV01110607; GAMS01005388; GAMR01002202

Gene Name

GNB4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000013134.2	ENSCJAT00000025533.2	ENSCJAP00000024139.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.00e-38	129.1	224	258
UBD/Beta-Prp	1.50e-51	176.3	46	268

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           gH +++++++f ++   +++GsdD t++++Dlr +
   Q: 224  GHVSDINAVSFfPNgYAFATGSDDATCRLFDLRAD 258
           8*********99885679**************987 PP

UBD/Beta-Prp

   S: 43   kllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee 131
            + r+l gh a+++a+ +  d+ +lv++s+D+ + +wd  t   +h++   ++ v+++++ psg++++ G+ d++  +++l+t++    
   Q: 46   RTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYNLKTREGNVR 134
           446899*****************************************************************************987776 PP
   S: 132  ...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrt 217
               l gh+g  +c ++ + ++ +v++s D+t+ lWd++t++  +t+tg h ++v sls++++++ +vsg++d + klwd++ g c ++
   Q: 135  vsrELPGHTGYLSCCRFLD-DSQIVTSSGDTTCALWDIETAQQTTTFTG-HSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQS 221
           6779*************99.67789***********************9.*************************************** PP
   S: 218  lnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn 264
           ++gh + ++ v f+pn+  +++gs+D + r++dlr ++ l  +++ n
   Q: 222  FTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHDN 268
           **************************************998888743 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MSELEQLRQE AEQLRNQIQD ARKACNDATL VQITSNMDSV GRIQMRTRRT LRGHLAKIYA 60
MHWGYDSRLL VSASQDGKLI IWDSYTTNKM HAIPLRSSWV MTCAYAPSGN FVACGGLDNI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCCCCCGGC CCGGGCCGCG CGCGCTCCGA GGGTCTGCGC GCCCCCGACA CGTCCCCGCC 60
CGTCCCGGCG CGCGCCGAGT TGCTGCTGCT AGGCGCGGGG CTGGGTGTGG CCGGCGGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR002469--Peptidase_S9B_N
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005765--C:lysosomal membrane
GO:0043209--C:myelin sheath
GO:0007165--P:signal transduction
GO:0021762--P:substantia nigra development

KEGG

cjc:100395633

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001727	Ailuropoda melanoleuca	99.38	0.00e+00	665.00
IUUC-Apl-003923	Anas platyrhynchos	94.44	3.00e-175	607.00
IUUC-Aca-004754	Anolis carolinensis	94.43	7.00e-176	609.00
IUUC-Ate-010520	Aspergillus terreus	61.44	1.00e-109	389.00
IUUC-Bta-013200	Bos taurus	99.38	0.00e+00	664.00
IUUC-Cfa-020395	Canis familiaris	99.38	0.00e+00	665.00
IUUC-Cpo-021376	Cavia porcellus	98.76	0.00e+00	663.00
IUUC-Csa-023295	Chlorocebus sabaeus	99.69	0.00e+00	666.00
IUUC-Cho-024766	Choloepus hoffmanni	99.08	0.00e+00	667.00
IUUC-Dno-029802	Dasypus novemcinctus	99.01	0.00e+00	625.00
IUUC-Ete-032710	Echinops telfairi	96.43	1.00e-179	621.00
IUUC-Eca-033628	Equus caballus	99.07	0.00e+00	663.00
IUUC-Eeu-034978	Erinaceus europaeus	97.07	2.00e-157	547.00
IUUC-Fal-037616	Ficedula albicollis	94.74	1.00e-176	611.00
IUUC-Gmo-039556	Gadus morhua	92.26	2.00e-180	624.00
IUUC-Gga-040249	Gallus gallus	94.74	1.00e-176	611.00
IUUC-Gac-041805	Gasterosteus aculeatus	91.33	3.00e-180	624.00
IUUC-Ggo-044954	Gorilla gorilla	99.38	0.00e+00	664.00
IUUC-Hsa-046105	Homo sapiens	99.69	0.00e+00	666.00
IUUC-Itr-048623	Ictidomys tridecemlineatus	99.69	0.00e+00	662.00
IUUC-Kpa-049192	Komagataella pastoris	38.89	6.00e-63	234.00
IUUC-Mcc-055787	Macaca mulatta	99.69	0.00e+00	666.00
IUUC-Mga-060050	Meleagris gallopavo	94.44	3.00e-175	607.00
IUUC-Mmr-060931	Microcebus murinus	99.69	0.00e+00	666.00
IUUC-Mdo-063055	Monodelphis domestica	94.12	8.00e-176	609.00
IUUC-Mmu-064368	Mus musculus	96.28	0.00e+00	649.00
IUUC-Mpu-066358	Mustela putorius furo	99.38	0.00e+00	665.00
IUUC-Mlu-067328	Myotis lucifugus	98.45	0.00e+00	658.00
IUUC-Nle-069612	Nomascus leucogenys	99.69	0.00e+00	666.00
IUUC-Ont-071287	Oreochromis niloticus	92.26	2.00e-180	624.00
IUUC-Oan-072913	Ornithorhynchus anatinus	95.05	2.00e-177	614.00
IUUC-Ocu-074126	Oryctolagus cuniculus	99.07	0.00e+00	668.00
IUUC-Ola-087297	Oryzias latipes	92.00	0.00e+00	626.00
IUUC-Oar-089360	Ovis aries	99.38	0.00e+00	664.00
IUUC-Ptr-091437	Pan troglodytes	99.69	0.00e+00	666.00
IUUC-Pan-092195	Papio anubis	100.00	0.00e+00	667.00
IUUC-Psi-093718	Pelodiscus sinensis	94.74	1.00e-176	611.00
IUUC-Pfo-096251	Poecilia formosa	91.95	1.00e-179	622.00
IUUC-Sce-106298	Saccharomyces cerevisiae	37.40	1.00e-68	253.00
IUUC-Sha-106534	Sarcophilus harrisii	94.12	5.00e-176	609.00
IUUC-Sja-107891	Schizosaccharomyces japonicus	35.48	9.00e-60	223.00
IUUC-Smo-108835	Selaginella moellendorffii	43.58	2.00e-74	272.00
IUUC-Sar-113642	Sorex araneus	98.90	9.00e-161	559.00
IUUC-Tgu-117198	Taeniopygia guttata	94.74	1.00e-176	611.00
IUUC-Tru-118399	Takifugu rubripes	91.64	4.00e-180	623.00
IUUC-Tsy-119354	Tarsius syrichta	96.28	0.00e+00	647.00
IUUC-Ttr-129243	Tursiops truncatus	99.69	0.00e+00	666.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence