iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-007149

UUCD1 version

UUC-ArT-01586

Ensembl Protein ID

AT1G14400.1

UniProt Accession

P25865; Q4TZ08; UBC1_ARATH

Genbank Protein ID

AAA32903.1; AAA32897.1; AAY44842.1; AAF43940.1; AEE29158.1; AEE29159.1; AAG48814.1; AAL49769.1; AAM14269.1; AAM63000.1; BAE98537.1; CAA81773.1

Protein Name

Ubiquitin-conjugating enzyme E2 1; E2 ubiquitin-conjugating enzyme 1; Ubiquitin carrier protein 1; Ubiquitin-conjugating enzyme E2-17 kDa 1; Ubiquitin-protein ligase 1

Genbank Nucleotide ID

M62721; L19351; DQ027016; AC012188; CP002684; CP002684; AF332451; AY070074; AY091330; AY085783; AK226391; Z27262

Gene Name

UBC1; At1g14400; F14L17.17; F14L17_35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT1G14400	AT1G14400.1	AT1G14400.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
Protein-protein Interaction
iRefIndex	PINA	HINT
Protein 3D Structure
PDB	MMDB
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E2/UBC	E2_UBC	16699537; 16339806

Classification

Family	E-value	Score	Start	End
E2/UBC	2.10e-53	180.7	8	142

Active Site

Position(s)	Description	Evidence
88	Glycyl thioester intermediate	N/A

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsv 98
           Rl++++k+l++dpp+gis  p+d+ +++ w+++i+Gp+dtp++gg+Fkl+++f+edYP kPP+v+f++++fhPn+y++G++Cl+il+  ++Wsp ++v
   Q: 8    RLMRDFKRLQQDPPAGISGAPQDN-NIMLWNAVIFGPDDTPWDGGTFKLSLQFSEDYPNKPPTVRFVSRMFHPNIYADGSICLDILQ--NQWSPIYDV 102
           9**********************9.9************************************************************9..********* PP
   S: 99   esvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           + +l+siqsll++pnp+sp+n+eaa++++++++ey+++vr
   Q: 103  AAILTSIQSLLCDPNPNSPANSEAARMYSESKREYNRRVR 142
           **************************************98 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.

Protein Sequence
(Fasta)

MSTPARKRLM RDFKRLQQDP PAGISGAPQD NNIMLWNAVI FGPDDTPWDG GTFKLSLQFS 60
EDYPNKPPTV RFVSRMFHPN IYADGSICLD ILQNQWSPIY DVAAILTSIQ SLLCDPNPNS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTAACTAAC ACTAATCTCC CGGTTAAAGT GTAGATTGCC CTAAACGGTT TAATTCCGGT 60
TAGGAACAAA CCAACCACTC GCTCGGTCGT CCAAAGGGCA AAGCGAATCC AACTTTACAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0006281--P:DNA repair
GO:0033523--P:histone H2B ubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process
GO:0010228--P:vegetative to reproductive phase transition of meristem

KEGG

ath:AT1G14400

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002120	Ailuropoda melanoleuca	76.51	8.00e-70	254.00
IUUC-Apl-004063	Anas platyrhynchos	70.55	4.00e-59	219.00
IUUC-Aca-005001	Anolis carolinensis	76.51	1.00e-69	254.00
IUUC-Aly-005584	Arabidopsis lyrata	100.00	2.00e-88	316.00
IUUC-Afl-008551	Aspergillus flavus	65.77	3.00e-60	223.00
IUUC-Afu-008980	Aspergillus fumigatus	65.77	3.00e-60	223.00
IUUC-Ang-009554	Aspergillus niger	65.77	3.00e-60	223.00
IUUC-Aor-010242	Aspergillus oryzae	65.77	3.00e-60	223.00
IUUC-Ate-010390	Aspergillus terreus	65.77	3.00e-60	223.00
IUUC-Ame-010844	Astyanax mexicanus	77.18	4.00e-71	259.00
IUUC-Bta-012840	Bos taurus	76.51	8.00e-70	254.00
IUUC-Bol-015726	Brassica oleracea	100.00	8.00e-89	320.00
IUUC-Bra-016809	Brassica rapa	100.00	8.00e-89	318.00
IUUC-Cel-018244	Caenorhabditis elegans	73.15	9.00e-69	251.00
IUUC-Cja-018783	Callithrix jacchus	77.18	5.00e-71	258.00
IUUC-Cfa-020646	Canis familiaris	77.18	1.00e-70	258.00
IUUC-Cpo-021323	Cavia porcellus	76.51	8.00e-71	258.00
IUUC-Csa-023588	Chlorocebus sabaeus	77.18	5.00e-71	258.00
IUUC-Cho-024773	Choloepus hoffmanni	60.40	9.00e-49	184.00
IUUC-Cin-025537	Ciona intestinalis	70.00	4.00e-55	206.00
IUUC-Csv-025846	Ciona savignyi	69.08	1.00e-58	218.00
IUUC-Cgl-026381	Colletotrichum gloeosporioides	66.44	2.00e-61	227.00
IUUC-Cme-027284	Cyanidioschyzon merolae	69.33	1.00e-57	215.00
IUUC-Dre-028774	Danio rerio	77.18	4.00e-71	259.00
IUUC-Dno-029661	Dasypus novemcinctus	76.51	8.00e-70	254.00
IUUC-Dor-030452	Dipodomys ordii	74.63	5.00e-61	225.00
IUUC-Dme-031863	Drosophila melanogaster	76.51	3.00e-70	256.00
IUUC-Ete-032595	Echinops telfairi	75.84	2.00e-69	253.00
IUUC-Eca-033377	Equus caballus	76.51	8.00e-70	254.00
IUUC-Eeu-035191	Erinaceus europaeus	60.26	2.00e-48	184.00
IUUC-Fca-036581	Felis catus	77.18	5.00e-71	258.00
IUUC-Fal-037474	Ficedula albicollis	75.00	6.00e-53	197.00
IUUC-Fox-037808	Fusarium oxysporum	66.44	3.00e-61	226.00
IUUC-Gmo-038517	Gadus morhua	77.18	5.00e-71	258.00
IUUC-Ggr-039875	Gaeumannomyces graminis	65.13	2.00e-61	226.00
IUUC-Gga-040588	Gallus gallus	77.18	5.00e-71	258.00
IUUC-Gac-041504	Gasterosteus aculeatus	76.51	1.00e-70	257.00
IUUC-Ggo-044896	Gorilla gorilla	77.18	5.00e-71	258.00
IUUC-Hsa-046383	Homo sapiens	77.18	5.00e-71	258.00
IUUC-Itr-048507	Ictidomys tridecemlineatus	77.18	5.00e-71	258.00
IUUC-Kpa-049225	Komagataella pastoris	65.33	2.00e-59	220.00
IUUC-Lch-050415	Latimeria chalumnae	77.18	2.00e-71	260.00
IUUC-Loc-051962	Lepisosteus oculatus	77.85	3.00e-71	259.00
IUUC-Laf-053680	Loxodonta africana	77.18	5.00e-71	258.00
IUUC-Mcc-055546	Macaca mulatta	77.18	2.00e-70	257.00
IUUC-Meu-056231	Macropus eugenii	77.18	5.00e-71	258.00
IUUC-Mor-057087	Magnaporthe oryzae	63.50	2.00e-53	200.00
IUUC-Mla-058876	Melampsora laricipopulina	69.33	7.00e-54	202.00
IUUC-Mga-059863	Meleagris gallopavo	73.72	1.00e-61	227.00
IUUC-Mmr-060630	Microcebus murinus	76.51	8.00e-70	254.00
IUUC-Mdo-062292	Monodelphis domestica	77.18	5.00e-71	258.00
IUUC-Mmu-063680	Mus musculus	77.18	5.00e-71	258.00
IUUC-Mpu-065803	Mustela putorius furo	76.51	8.00e-70	254.00
IUUC-Mlu-067147	Myotis lucifugus	76.51	8.00e-70	254.00
IUUC-Nfi-068580	Neosartorya fischeri	65.77	3.00e-60	223.00
IUUC-Nle-069121	Nomascus leucogenys	77.18	5.00e-71	258.00
IUUC-Opr-070935	Ochotona princeps	76.51	8.00e-70	254.00
IUUC-Ont-071716	Oreochromis niloticus	78.00	1.00e-70	257.00
IUUC-Oan-072706	Ornithorhynchus anatinus	70.55	1.00e-62	231.00
IUUC-Ocu-074550	Oryctolagus cuniculus	77.18	1.00e-70	258.00
IUUC-Ola-087448	Oryzias latipes	78.00	8.00e-71	258.00
IUUC-Olu-087830	Ostreococcus lucimarinus	77.85	1.00e-62	230.00
IUUC-Oga-088659	Otolemur garnettii	77.18	5.00e-71	258.00
IUUC-Oar-090141	Ovis aries	76.51	8.00e-70	254.00
IUUC-Ptr-091305	Pan troglodytes	77.18	5.00e-71	258.00
IUUC-Pan-092740	Papio anubis	77.18	2.00e-70	257.00
IUUC-Psi-094094	Pelodiscus sinensis	77.18	5.00e-71	258.00
IUUC-Pma-094376	Petromyzon marinus	77.85	7.00e-71	258.00
IUUC-Ppa-095689	Physcomitrella patens	93.42	8.00e-73	265.00
IUUC-Pfo-096656	Poecilia formosa	76.51	8.00e-71	258.00
IUUC-Pab-097972	Pongo abelii	77.18	5.00e-71	258.00
IUUC-Pca-100906	Procavia capensis	73.83	1.00e-65	241.00
IUUC-Pva-102380	Pteropus vampyrus	77.18	1.00e-69	254.00
IUUC-Pgr-103611	Puccinia graminis	69.13	3.00e-54	203.00
IUUC-Ptt-103971	Puccinia triticina	68.97	3.00e-40	155.00
IUUC-Pte-104378	Pyrenophora teres	66.44	2.00e-61	226.00
IUUC-Pyt-104757	Pyrenophora triticirepentis	66.44	2.00e-61	226.00
IUUC-Rno-105772	Rattus norvegicus	76.51	3.00e-70	256.00
IUUC-Sha-107650	Sarcophilus harrisii	75.84	2.00e-68	250.00
IUUC-Sja-107790	Schizosaccharomyces japonicus	70.86	2.00e-56	210.00
IUUC-Spo-108073	Schizosaccharomyces pombe	70.86	1.00e-56	211.00
IUUC-Smo-109036	Selaginella moellendorffii	94.08	2.00e-85	306.00
IUUC-Sar-113429	Sorex araneus	76.51	8.00e-70	254.00
IUUC-Sre-115106	Sporisorium reilianum	71.71	9.00e-57	211.00
IUUC-Ssc-116265	Sus scrofa	77.18	5.00e-71	258.00
IUUC-Tgu-117383	Taeniopygia guttata	77.18	5.00e-71	258.00
IUUC-Tru-118576	Takifugu rubripes	78.00	1.00e-70	257.00
IUUC-Tsy-119000	Tarsius syrichta	76.51	8.00e-70	254.00
IUUC-Tni-119745	Tetraodon nigroviridis	78.52	1.00e-70	257.00
IUUC-Tre-122002	Trichoderma reesei	66.44	4.00e-61	226.00
IUUC-Tvi-122331	Trichoderma virens	66.44	4.00e-61	226.00
IUUC-Tae-124461	Triticum aestivum	95.39	2.00e-86	311.00
IUUC-Tbe-127921	Tupaia belangeri	74.50	2.00e-65	240.00
IUUC-Ttr-129121	Tursiops truncatus	76.51	8.00e-70	254.00
IUUC-Uma-129561	Ustilago maydis	71.71	6.00e-57	212.00
IUUC-Vda-129711	Verticillium dahliae	66.44	2.00e-61	227.00
IUUC-Vpa-130570	Vicugna pacos	71.64	1.00e-56	211.00
IUUC-Xtr-132301	Xenopus tropicalis	77.18	5.00e-71	258.00
IUUC-Xma-133937	Xiphophorus maculatus	77.18	5.00e-71	258.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence