iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093968

Ensembl Protein ID

ENSPSIP00000005319.1

UniProt Accession

K7FBA9; K7FBA9_PELSI

Genbank Protein ID

ENSPSIP00000005319

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01039715

Gene Name

UBE2B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000004966.1	ENSPSIT00000005350.1	ENSPSIP00000005319.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.00e-54	184.1	8	142

Active Site

Position(s)	Description	Evidence
88	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           Rl++++k+l++dpp g+s  p+++ ++++w+++i+Gpe+tp+e+g+Fkl ief+e+YP kPP+v+fl+k+fhPnvy++G++Cl+il+  
   Q: 8    RLMRDFKRLQEDPPVGVSGAPSEN-NIMQWNAVIFGPEGTPFEDGTFKLIIEFSEEYPNKPPTVRFLSKMFHPNVYADGSICLDILQ-- 93
           9**********************9.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++Wsp+++v+s+l+siqsll+epnp+sp+n++aa+l+++n++ey+k+v+
   Q: 94   NRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVS 142
           **********************************************996 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MSTPARRRLM RDFKRLQEDP PVGVSGAPSE NNIMQWNAVI FGPEGTPFED GTFKLIIEFS 60
EEYPNKPPTV RFLSKMFHPN VYADGSICLD ILQNRWSPTY DVSSILTSIQ SLLDEPNPNS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCGGCAGAG CGAGTGGTAC GGTCGCGGAG GAGCCTGTGA CTTTCCCTCC CCCCGGCGGA 60
GGGAGACGCC ATTGCAGGGT TGTTTGTGTA GCCGCTGCGG GCTGGGGAGG GAGACCGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0033503--C:HULC complex
GO:0000790--C:nuclear chromatin
GO:0005657--C:replication fork
GO:0001741--C:XY body
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0060070--P:canonical Wnt signaling pathway
GO:0051026--P:chiasma assembly
GO:0033522--P:histone H2A ubiquitination
GO:0070076--P:histone lysine demethylation
GO:0006344--P:maintenance of chromatin silencing
GO:0045141--P:meiotic telomere clustering
GO:0043066--P:negative regulation of apoptotic process
GO:0043951--P:negative regulation of cAMP-mediated signaling
GO:0033128--P:negative regulation of histone phosphorylation
GO:0010845--P:positive regulation of reciprocal meiotic recombination
GO:0006301--P:postreplication repair
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0050821--P:protein stabilization
GO:0042493--P:response to drug
GO:0009411--P:response to UV
GO:0007288--P:sperm axoneme assembly
GO:0070193--P:synaptonemal complex organization

KEGG

pss:102445549

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002120	Ailuropoda melanoleuca	99.34	6.00e-88	315.00
IUUC-Apl-004063	Anas platyrhynchos	91.95	2.00e-76	276.00
IUUC-Aca-005001	Anolis carolinensis	100.00	5.00e-88	315.00
IUUC-Ago-007745	Ashbya gossypii	69.80	8.00e-63	232.00
IUUC-Ame-010743	Astyanax mexicanus	96.05	1.00e-84	304.00
IUUC-Bta-012840	Bos taurus	99.34	6.00e-88	315.00
IUUC-Cja-019737	Callithrix jacchus	99.34	6.00e-88	315.00
IUUC-Cfa-020244	Canis familiaris	99.34	6.00e-88	315.00
IUUC-Cpo-022192	Cavia porcellus	99.34	6.00e-88	315.00
IUUC-Cre-022822	Chlamydomonas reinhardtii	75.97	9.00e-58	215.00
IUUC-Csa-023430	Chlorocebus sabaeus	99.34	6.00e-88	315.00
IUUC-Cho-024773	Choloepus hoffmanni	79.61	9.00e-65	238.00
IUUC-Dno-029661	Dasypus novemcinctus	99.34	6.00e-88	315.00
IUUC-Dor-030452	Dipodomys ordii	99.27	2.00e-78	283.00
IUUC-Ete-032595	Echinops telfairi	96.05	4.00e-85	306.00
IUUC-Eca-033377	Equus caballus	99.34	6.00e-88	315.00
IUUC-Fca-036336	Felis catus	99.34	6.00e-88	315.00
IUUC-Gga-040494	Gallus gallus	99.34	6.00e-88	315.00
IUUC-Hsa-046239	Homo sapiens	99.34	6.00e-88	315.00
IUUC-Itr-048960	Ictidomys tridecemlineatus	99.34	6.00e-88	315.00
IUUC-Lch-050283	Latimeria chalumnae	96.69	1.00e-85	307.00
IUUC-Loc-051962	Lepisosteus oculatus	97.37	3.00e-86	309.00
IUUC-Laf-053380	Loxodonta africana	99.34	6.00e-88	315.00
IUUC-Mcc-054819	Macaca mulatta	99.34	4.00e-88	316.00
IUUC-Mla-058876	Melampsora laricipopulina	73.51	1.00e-58	218.00
IUUC-Mga-059863	Meleagris gallopavo	97.86	5.00e-79	285.00
IUUC-Mmr-060630	Microcebus murinus	99.34	6.00e-88	315.00
IUUC-Mdo-062676	Monodelphis domestica	99.34	6.00e-88	315.00
IUUC-Mmu-063491	Mus musculus	99.34	6.00e-88	315.00
IUUC-Mpu-065803	Mustela putorius furo	99.34	6.00e-88	315.00
IUUC-Mlu-067147	Myotis lucifugus	99.34	6.00e-88	315.00
IUUC-Nle-070105	Nomascus leucogenys	99.34	6.00e-88	315.00
IUUC-Opr-070935	Ochotona princeps	99.34	6.00e-88	315.00
IUUC-Oan-072706	Ornithorhynchus anatinus	93.96	2.00e-80	290.00
IUUC-Ocu-074130	Oryctolagus cuniculus	99.34	6.00e-88	315.00
IUUC-Oga-088836	Otolemur garnettii	99.34	6.00e-88	315.00
IUUC-Oar-090141	Ovis aries	99.34	6.00e-88	315.00
IUUC-Ptr-091453	Pan troglodytes	99.34	6.00e-88	315.00
IUUC-Pan-092511	Papio anubis	99.34	6.00e-88	315.00
IUUC-Pno-094935	Phaeosphaeria nodorum	68.21	3.00e-64	236.00
IUUC-Pab-098121	Pongo abelii	99.34	6.00e-88	315.00
IUUC-Pgr-103611	Puccinia graminis	72.85	7.00e-59	219.00
IUUC-Ptt-103971	Puccinia triticina	73.73	1.00e-44	171.00
IUUC-Pte-104378	Pyrenophora teres	68.87	1.00e-64	237.00
IUUC-Pyt-104757	Pyrenophora triticirepentis	68.87	1.00e-64	237.00
IUUC-Rno-105772	Rattus norvegicus	99.34	3.00e-88	317.00
IUUC-Sha-107650	Sarcophilus harrisii	98.03	5.00e-86	308.00
IUUC-Sar-113429	Sorex araneus	99.34	6.00e-88	315.00
IUUC-Ssc-115257	Sus scrofa	97.37	7.00e-86	308.00
IUUC-Tgu-116604	Taeniopygia guttata	93.21	1.00e-85	307.00
IUUC-Tru-118576	Takifugu rubripes	94.74	7.00e-84	301.00
IUUC-Tsy-119000	Tarsius syrichta	99.34	6.00e-88	315.00
IUUC-Tni-119745	Tetraodon nigroviridis	94.74	5.00e-84	302.00
IUUC-Tbe-127921	Tupaia belangeri	97.37	2.00e-83	300.00
IUUC-Ttr-129121	Tursiops truncatus	99.34	6.00e-88	315.00
IUUC-Uma-129561	Ustilago maydis	73.51	5.00e-60	223.00
IUUC-Vpa-130570	Vicugna pacos	92.70	2.00e-71	259.00
IUUC-Xtr-131824	Xenopus tropicalis	98.03	1.00e-86	311.00
IUUC-Yli-134660	Yarrowia lipolytica	65.56	7.00e-63	232.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence