iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sly-110914

Ensembl Protein ID

Solyc09g018450.2.1

UniProt Accession

K4CSA9; K4CSA9_SOLLC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Solyc09g018450.2	Solyc09g018450.2.1	Solyc09g018450.2.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	3.40e-172	574.0	479	966

Active Site

Position(s)	Description	Evidence
660	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnp 86
           YD Qi ++G + q+kl++ak+++vG g+lGcE+lKnL+l+Gv     g++t++D+d +e+snl+rqFLfr++++g+ K+ vaa+a+  +np
   Q: 479  YDAQISVFGNKLQQKLEEAKAFVVGSGALGCEFLKNLALMGVccgveGKLTITDDDVIEKSNLSRQFLFRDWNIGQAKSTVAAAAASLINP 569
           ******************************************************************************************* PP
   S: 87   dvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfc 174
            +++ea +++ ++++e+++   F ++++vVv+aldn+ ar++++++cl+ ++pl+esgtlG + +++ +i++lte y +s+dpp+k++P+c
   Q: 570  RIRIEALQNRASPETESVFddtFWENLSVVVNALDNVNARLYIDQRCLYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMC 660
           *****************99************************************************************************ PP
   S: 175  tlketpnaaehtiewa.............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttins 252
           t+ ++p +++h+++wa             ++ + l+++++  ++ ++    ++ ++++d+v + l +e+ ++fe++i++a+  f+ ++   
   Q: 661  TVHSFPHNIDHCLTWArsefegllektptEVNAYLINPTDYISSMQK-AGDAQARDILDRVLECLDKERCDSFEDCITWARLRFEDYFADR 750
           ****************************7666666777776666665.677999************************************* PP
   S: 253  ikqllksfecdivtkskspfwv.........................................................sfcsnaealqvp 286
           +kql+  f+ d  t+s++pfw+                                                          f + ++ + v 
   Q: 751  VKQLTYTFPEDAATSSGAPFWSapkrfprplqfsvddashlqfllaasmlraetfgisipdwvnspqklaeavdkvmvpDFQPKKDVKIVT 841
           ****************************************************************999888888877777555555544444 PP
   S: 287  ekvekdeevvkasap..lylllralerfekk..kgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiat 371
           +  + ++ +++ +++  +  l+  le+ ++k  +g k++ ++fekddd   ++d+++ +an+ra +++i++ +d+ + k iag+iipaiat
   Q: 842  DEKATSMSASSIDDAavINELVMQLETCRQKlpSGYKMNPIQFEKDDDTnyHMDFIAGLANMRARNYSIPE-VDKLKAKFIAGRIIPAIAT 931
           4444444444444446977777778777766447899999*******************************.******************* PP
   S: 372  tnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
            +a+  Gl+++E++Kv++g  k e ++n+f ++a+
   Q: 932  STAMATGLVCLELYKVLNGghKVEDYRNTFANLAL 966
           *******************999********99875 PP

Organism

Solanum lycopersicum

Protein Sequence
(Fasta)

MLPVKRSSIV EVGGDNDGGS VDPLTKKYKT AAAAAGGDSS TVTMAGAGSA TGDVSANGNA 60
TNGRTGGVSP VDLRNLSDID EDLHSRQLAV YGRETMRKLF AANVLISGLQ GLGAEIAKNL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATCTAAGCT CAAAGCATCT CTCATACAAA CCCTAATCAT CACGCGCATC TCATTTCACT 60
TCCTTCACTC CTTCATATTC TCCATTCTTG GTACCCTCTC TTCCTATTTA ACATTTCTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

KEGG

sly:101253520

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002684	Amborella trichopoda	79.72	0.00e+00	1675.00
IUUC-Apl-004158	Anas platyrhynchos	38.71	0.00e+00	665.00
IUUC-Aca-004620	Anolis carolinensis	43.92	0.00e+00	871.00
IUUC-Ago-007873	Ashbya gossypii	46.27	0.00e+00	845.00
IUUC-Acl-008181	Aspergillus clavatus	44.18	0.00e+00	822.00
IUUC-Afu-009065	Aspergillus fumigatus	45.02	0.00e+00	853.00
IUUC-Ate-010466	Aspergillus terreus	45.64	0.00e+00	868.00
IUUC-Ame-010933	Astyanax mexicanus	43.59	0.00e+00	841.00
IUUC-Bgr-012281	Blumeria graminis	44.97	0.00e+00	824.00
IUUC-Bci-013721	Botrytis cinerea	45.92	0.00e+00	809.00
IUUC-Bol-015880	Brassica oleracea	79.35	0.00e+00	1731.00
IUUC-Bra-017252	Brassica rapa	79.35	0.00e+00	1731.00
IUUC-Cel-018260	Caenorhabditis elegans	39.90	0.00e+00	668.00
IUUC-Cja-019152	Callithrix jacchus	43.91	0.00e+00	886.00
IUUC-Cfa-020622	Canis familiaris	42.63	0.00e+00	837.00
IUUC-Cpo-022526	Cavia porcellus	43.74	0.00e+00	875.00
IUUC-Cre-022702	Chlamydomonas reinhardtii	58.04	0.00e+00	1153.00
IUUC-Cin-025790	Ciona intestinalis	44.81	0.00e+00	882.00
IUUC-Csv-026084	Ciona savignyi	44.05	0.00e+00	862.00
IUUC-Cgl-026512	Colletotrichum gloeosporioides	45.91	0.00e+00	885.00
IUUC-Cne-026960	Cryptococcus neoformans	45.07	0.00e+00	868.00
IUUC-Dre-028149	Danio rerio	44.18	0.00e+00	868.00
IUUC-Dno-028884	Dasypus novemcinctus	43.45	0.00e+00	881.00
IUUC-Dor-030229	Dipodomys ordii	42.24	0.00e+00	830.00
IUUC-Dse-031524	Dothistroma septosporum	42.95	0.00e+00	819.00
IUUC-Dme-032045	Drosophila melanogaster	44.16	0.00e+00	841.00
IUUC-Ete-033124	Echinops telfairi	39.00	6.00e-127	447.00
IUUC-Fca-036255	Felis catus	44.02	0.00e+00	874.00
IUUC-Fal-036848	Ficedula albicollis	38.32	0.00e+00	672.00
IUUC-Fox-038007	Fusarium oxysporum	46.98	5.00e-133	467.00
IUUC-Fso-038339	Fusarium solani	46.60	0.00e+00	834.00
IUUC-Gmo-039338	Gadus morhua	43.02	0.00e+00	822.00
IUUC-Ggr-039823	Gaeumannomyces graminis	45.11	0.00e+00	880.00
IUUC-Gga-040747	Gallus gallus	38.12	0.00e+00	659.00
IUUC-Gac-041773	Gasterosteus aculeatus	44.25	0.00e+00	839.00
IUUC-Gma-043198	Glycine max	83.37	0.00e+00	1750.00
IUUC-Ggo-045336	Gorilla gorilla	43.73	0.00e+00	867.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	43.92	0.00e+00	884.00
IUUC-Kpa-049112	Komagataella pastoris	45.96	0.00e+00	858.00
IUUC-Lch-050371	Latimeria chalumnae	44.63	0.00e+00	879.00
IUUC-Lpe-051299	Leersia perrieri	75.15	0.00e+00	1613.00
IUUC-Loc-052936	Lepisosteus oculatus	44.70	0.00e+00	880.00
IUUC-Lma-053315	Leptosphaeria maculans	45.76	0.00e+00	880.00
IUUC-Meu-056258	Macropus eugenii	43.54	0.00e+00	869.00
IUUC-Mor-057269	Magnaporthe oryzae	44.88	0.00e+00	858.00
IUUC-Mpo-057435	Magnaporthe poae	45.51	0.00e+00	866.00
IUUC-Mvi-060437	Microbotryum violaceum	42.70	0.00e+00	810.00
IUUC-Mmr-061405	Microcebus murinus	42.80	0.00e+00	845.00
IUUC-Mdo-062032	Monodelphis domestica	43.01	0.00e+00	850.00
IUUC-Mmu-063721	Mus musculus	44.97	0.00e+00	882.00
IUUC-Mac-065505	Musa acuminata	78.54	0.00e+00	1658.00
IUUC-Mlu-067217	Myotis lucifugus	43.96	0.00e+00	872.00
IUUC-Nfi-068407	Neosartorya fischeri	45.26	0.00e+00	836.00
IUUC-Ncr-068698	Neurospora crassa	45.76	0.00e+00	861.00
IUUC-Nle-070072	Nomascus leucogenys	41.16	0.00e+00	790.00
IUUC-Opr-070715	Ochotona princeps	35.77	2.00e-153	535.00
IUUC-Ont-071671	Oreochromis niloticus	44.94	0.00e+00	863.00
IUUC-Oan-073268	Ornithorhynchus anatinus	38.58	5.00e-178	617.00
IUUC-Ocu-074544	Oryctolagus cuniculus	43.91	0.00e+00	888.00
IUUC-Ogu-078305	Oryza glumaepatula	75.46	0.00e+00	1610.00
IUUC-Olo-081089	Oryza longistaminata	75.75	0.00e+00	1615.00
IUUC-Opu-083301	Oryza punctata	77.49	0.00e+00	1621.00
IUUC-Oru-084469	Oryza rufipogon	75.66	0.00e+00	1612.00
IUUC-Ola-087002	Oryzias latipes	45.80	0.00e+00	874.00
IUUC-Olu-087687	Ostreococcus lucimarinus	58.84	0.00e+00	1138.00
IUUC-Oga-088594	Otolemur garnettii	44.06	0.00e+00	869.00
IUUC-Oar-090068	Ovis aries	43.98	0.00e+00	883.00
IUUC-Ptr-090609	Pan troglodytes	37.75	0.00e+00	660.00
IUUC-Pma-094214	Petromyzon marinus	47.37	1.00e-35	141.00
IUUC-Pno-095154	Phaeosphaeria nodorum	44.21	0.00e+00	863.00
IUUC-Ppa-095227	Physcomitrella patens	72.57	0.00e+00	1511.00
IUUC-Pab-097861	Pongo abelii	43.63	0.00e+00	853.00
IUUC-Pop-098934	Populus trichocarpa	79.03	0.00e+00	1736.00
IUUC-Pca-100347	Procavia capensis	42.31	0.00e+00	699.00
IUUC-Ppe-102012	Prunus persica	82.91	0.00e+00	1787.00
IUUC-Pva-102584	Pteropus vampyrus	44.21	0.00e+00	912.00
IUUC-Pte-104200	Pyrenophora teres	45.76	0.00e+00	889.00
IUUC-Pyt-104441	Pyrenophora triticirepentis	44.91	0.00e+00	883.00
IUUC-Rno-105462	Rattus norvegicus	43.08	0.00e+00	860.00
IUUC-Sce-106245	Saccharomyces cerevisiae	44.94	0.00e+00	880.00
IUUC-Sha-107142	Sarcophilus harrisii	43.46	0.00e+00	875.00
IUUC-Sja-107841	Schizosaccharomyces japonicus	44.28	0.00e+00	850.00
IUUC-Spo-108034	Schizosaccharomyces pombe	43.65	0.00e+00	846.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	45.73	0.00e+00	829.00
IUUC-Stu-112109	Solanum tuberosum	97.70	0.00e+00	2111.00
IUUC-Sar-113737	Sorex araneus	44.17	0.00e+00	877.00
IUUC-Ssc-115777	Sus scrofa	43.91	0.00e+00	882.00
IUUC-Tgu-116565	Taeniopygia guttata	38.32	0.00e+00	669.00
IUUC-Tru-118742	Takifugu rubripes	43.99	0.00e+00	815.00
IUUC-Tsy-119436	Tarsius syrichta	34.31	2.00e-157	549.00
IUUC-Tni-120401	Tetraodon nigroviridis	44.18	0.00e+00	824.00
IUUC-Tca-121436	Theobroma cacao	79.42	0.00e+00	1775.00
IUUC-Tre-122009	Trichoderma reesei	46.91	0.00e+00	845.00
IUUC-Tvi-122259	Trichoderma virens	45.69	0.00e+00	822.00
IUUC-Tbe-127714	Tupaia belangeri	34.14	4.00e-138	484.00
IUUC-Ttr-128331	Tursiops truncatus	43.93	0.00e+00	868.00
IUUC-Vda-129977	Verticillium dahliae	47.80	0.00e+00	816.00
IUUC-Vpa-130716	Vicugna pacos	37.07	0.00e+00	650.00
IUUC-Vvi-131026	Vitis vinifera	84.67	0.00e+00	1817.00
IUUC-Yli-134547	Yarrowia lipolytica	44.37	0.00e+00	858.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence