iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010968

Ensembl Protein ID

ENSAMXP00000002776.1

UniProt Accession

W5K5B5; W5K5B5_ASTMX

Genbank Protein ID

ENSAMXP00000002776

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01036098

Gene Name

USP31

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000002715.1	ENSAMXT00000002776.1	ENSAMXP00000002776.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.60e-93	312.7	92	731

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle...kkkeklneenp.............kepkgellkslqklfeelwkskkkavsprell 74
           GlkN+gNtC+mN++LQcLsn+  ++e+l     +   ++  e++              ++kg+++++l+ l+++lw+ + +    re++
   Q: 92   GLKNHGNTCFMNAILQCLSNTDLFAEYLALeqfR--GDVTTEEEkpktngvhlqrkgAQSKGDVTEHLAGLVRALWTFEYTPHHSREFK 178
           9**************************9886551..33333333445555666666678888*************************** PP
   S: 75   kalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvs 163
           +a++k a +++g++q+DaqEfl +lld+++e+l+    +++ + +   +++    +  + + +  s++++lFq q++s+++c++c+++s
   Q: 179  NAVSKRAMQYRGNAQHDAQEFLLWLLDRVHEDLNA-VGHSRASIKPPIEEDDGALEGPSLPLSAGSFVQELFQAQYRSSLTCPHCQKQS 266
           *********************************66.33333333333333334447778888999************************ PP
   S: 164  sreepfldlslpvpgkeetkke................................................................... 185
           ++++pfl +slp+p  +++ ++                                                                   
   Q: 267  NTFDPFLCISLPIPLPHTR-PLyvtvvyqgkyshcmrigvavplnstvsrlreavsretkippdqfvltemyydgfhrsfcdddddldi 354
           **************87755.34689**************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 355  iqesdsifafetpetfrlenirskrgsllanlnqnnlkygsemvrtpsfmqgavnpaspnknagadkmillicnractghqgrrfglpf 443
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 444  vlymertvtwdvlqkailekmhhllrqgvyiqvgpfslrvvgvvgityllpqeehplchptveraykscgqggpphvkivvewdketkd 532
           ***************************************************************************************** PP
   S: 186  ..............................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqk 244
                                         +l +c++ +tkee+l  ++++ c++ck++q+ + kl+l++lP+vLilhLkRf  ++e++
   Q: 533  ylfghteeeyipdaesvylhreqhhqpqacTLAQCFQLYTKEEQLAPDDAWRCPHCKQLQQGRIKLSLWTLPDVLILHLKRF--RQEGD 619
           **********************************************************************************..99*** PP
   S: 245  srekinkkvefple.Ldlspfctspeekqke...................kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDs 312
           +r k+++ v fpl  +d++p+++++++++ +                   ++ Y+L+av++H+G++++GHY+ay+kn  +g+W++fdDs
   Q: 620  RRVKMQNMVRFPLVgMDMAPHMVKRSQSSWSlpshwspwrrpyglgrnpeDYLYDLYAVCNHHGNMHGGHYTAYCKNsIDGQWYCFDDS 708
           ************************77666559999999999999999999***************************66888******* PP
   S: 313  kVtevkeeevleetgstaYvlfYkrr 338
           +V++v  e+v++   +taY+lfY+rr
   Q: 709  EVQPVADEDVCQ---QTAYILFYQRR 731
           ************...*********96 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MSTKSSTKEK KSGLSKKLFR RGSVRSVGSF MNRVLKTLTT LSHFGSELHA AEGEKDDGGF 60
TAFKVDGKGS VASDESDCGG FLSRDKIPGV SGLKNHGNTC FMNAILQCLS NTDLFAEYLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGACCA AATCTTCGAC CAAGGAGAAA AAGTCAGGCC TGAGCAAGAA GCTCTTCCGG 60
AGAGGCTCGG TACGCTCAGT GGGGAGTTTT ATGAACAGGG TCTTGAAGAC CCTTACAACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001207	Ailuropoda melanoleuca	67.10	0.00e+00	1067.00
IUUC-Apl-003186	Anas platyrhynchos	69.94	0.00e+00	1011.00
IUUC-Aca-004949	Anolis carolinensis	69.27	0.00e+00	1081.00
IUUC-Bta-013271	Bos taurus	66.92	0.00e+00	1059.00
IUUC-Cja-019663	Callithrix jacchus	68.21	0.00e+00	966.00
IUUC-Cfa-021258	Canis familiaris	67.21	0.00e+00	1087.00
IUUC-Csa-024188	Chlorocebus sabaeus	69.59	0.00e+00	1064.00
IUUC-Cho-024813	Choloepus hoffmanni	66.39	0.00e+00	829.00
IUUC-Csv-026086	Ciona savignyi	39.97	3.00e-131	462.00
IUUC-Dre-027372	Danio rerio	81.63	0.00e+00	1512.00
IUUC-Dno-029964	Dasypus novemcinctus	67.54	0.00e+00	983.00
IUUC-Dor-030448	Dipodomys ordii	64.04	2.00e-167	583.00
IUUC-Dme-032088	Drosophila melanogaster	46.04	9.00e-66	245.00
IUUC-Ete-032975	Echinops telfairi	55.04	0.00e+00	715.00
IUUC-Eca-034030	Equus caballus	68.20	0.00e+00	1042.00
IUUC-Eeu-034629	Erinaceus europaeus	53.25	0.00e+00	658.00
IUUC-Fca-035788	Felis catus	68.00	0.00e+00	1033.00
IUUC-Fal-036874	Ficedula albicollis	69.61	0.00e+00	999.00
IUUC-Gmo-039479	Gadus morhua	72.57	0.00e+00	1607.00
IUUC-Gga-041092	Gallus gallus	65.86	0.00e+00	1132.00
IUUC-Gac-041778	Gasterosteus aculeatus	73.79	0.00e+00	1599.00
IUUC-Hsa-046805	Homo sapiens	67.85	0.00e+00	1105.00
IUUC-Itr-048158	Ictidomys tridecemlineatus	68.82	0.00e+00	991.00
IUUC-Lch-050332	Latimeria chalumnae	61.53	0.00e+00	1247.00
IUUC-Loc-051953	Lepisosteus oculatus	68.75	0.00e+00	1502.00
IUUC-Mcc-055398	Macaca mulatta	68.97	0.00e+00	1101.00
IUUC-Meu-056822	Macropus eugenii	62.95	0.00e+00	843.00
IUUC-Mga-060115	Meleagris gallopavo	67.50	0.00e+00	1000.00
IUUC-Mmr-061150	Microcebus murinus	67.44	0.00e+00	1064.00
IUUC-Mdo-062700	Monodelphis domestica	68.52	0.00e+00	1149.00
IUUC-Mmu-063512	Mus musculus	70.39	0.00e+00	1056.00
IUUC-Mpu-066059	Mustela putorius furo	66.03	0.00e+00	907.00
IUUC-Mlu-067870	Myotis lucifugus	68.85	0.00e+00	1012.00
IUUC-Nle-069898	Nomascus leucogenys	67.85	0.00e+00	1101.00
IUUC-Ont-072354	Oreochromis niloticus	74.81	0.00e+00	1613.00
IUUC-Oan-073175	Ornithorhynchus anatinus	69.89	0.00e+00	982.00
IUUC-Ola-086745	Oryzias latipes	72.99	0.00e+00	1523.00
IUUC-Oga-089021	Otolemur garnettii	67.85	0.00e+00	1086.00
IUUC-Oar-090016	Ovis aries	66.81	0.00e+00	1063.00
IUUC-Ptr-090864	Pan troglodytes	67.64	0.00e+00	1102.00
IUUC-Pan-092370	Papio anubis	69.68	0.00e+00	1068.00
IUUC-Psi-093881	Pelodiscus sinensis	66.99	0.00e+00	981.00
IUUC-Pfo-097171	Poecilia formosa	73.07	0.00e+00	1568.00
IUUC-Pab-098104	Pongo abelii	66.09	0.00e+00	1060.00
IUUC-Pca-100640	Procavia capensis	72.12	3.00e-89	323.00
IUUC-Pva-102287	Pteropus vampyrus	67.23	0.00e+00	930.00
IUUC-Rno-106033	Rattus norvegicus	67.83	0.00e+00	1059.00
IUUC-Sha-107041	Sarcophilus harrisii	71.81	0.00e+00	1006.00
IUUC-Tru-117929	Takifugu rubripes	73.33	0.00e+00	1545.00
IUUC-Tsy-118887	Tarsius syrichta	63.33	0.00e+00	896.00
IUUC-Tbe-127491	Tupaia belangeri	76.81	2.00e-63	237.00
IUUC-Ttr-128210	Tursiops truncatus	65.27	0.00e+00	1031.00
IUUC-Vpa-130222	Vicugna pacos	64.14	2.00e-160	559.00
IUUC-Xtr-132509	Xenopus tropicalis	69.09	0.00e+00	1024.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence