iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000002035.1	ENSSHAT00000002314.1	ENSSHAP00000002290.1
ENSSHAG00000002035.1	ENSSHAT00000002315.1	ENSSHAP00000002291.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-30	103.9	1529	1562
UBD/Beta-Prp	1.70e-42	145.8	1395	1599

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           H+d+v++laf ++ ++l+s ++ g ikvW++  +
   Q: 1529 HKDWVCALAFvPGrPMLLSTCRGGFIKVWNVENF 1562
           ***********999****************9765 PP

UBD/Beta-Prp

   S: 50   gheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sg.dklvsGshdrtirvwdletgqclee.. 131
           + e +++++ ++p+g + + +++ + ++vw+l+ ++++ +l+gh   v++l++s+  ++ d +v+Gs+d ++++++l  g+c+    
   Q: 1395 QGEHQINQIALNPTG-TTLYAASGNSVRVWELNRFQPIGKLTGHIGPVMCLTVSQtsNQhDLVVTGSKDHYVKMFEL--GECVMGni 1478
           45678*********9.8999999********************************98445***************66..55665556 PP
   S: 132  .....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtge 213
                ++ +h + + c+++++  ++l+sGs D+ ++ Wdl++++l+++   +h+d v  l+f + ++ l+s  + g +k+w++++ +
   Q: 1479 spthnFEPPHYDGIECLAIQG--DILFSGSRDNGIKKWDLEQQELIQQIPNAHKDWVCALAFVPGRPMLLSTCRGGFIKVWNVENFT 1563
           8888899**************..**************************999*********************************** PP
   S: 214  cvrtlnghtdnvksvrfspnderlvsgssDgsiriWdl 251
            + + +gh+++++ + +   ++++ ++ssD ++++W+ 
   Q: 1564 PIGEIKGHDSPINAICTN--SKHIFTASSDLTVKLWNG 1599
           *************87777..****************95 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

RIRPQLSKEK IEGCHICTSV TPGEPQVLLG KDKAFTYDFV FDLDTWQEQI YTACVGKLIE 60
GCFEGYNATV LAYGQTGAGK TYTMGTGFDM STSEEEHGII PRAIAHLFGG IAERKKRAQE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGCAGTGCA GCTGGGGAGC ATGATGGGCA GATGCCAGGG GCCCTTGGCC ATGGTGCTGC 60
TCCTGAACCA GCACCGTGGC CTACTCAAAA TGGCATTTCT TCTGTGCTTC CTTTCTTGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001279	Ailuropoda melanoleuca	89.76	0.00e+00	2665.00
IUUC-Apl-003204	Anas platyrhynchos	76.61	0.00e+00	1594.00
IUUC-Aca-004506	Anolis carolinensis	81.54	0.00e+00	1565.00
IUUC-Bta-013185	Bos taurus	70.97	0.00e+00	1989.00
IUUC-Cja-018844	Callithrix jacchus	87.13	0.00e+00	2596.00
IUUC-Cfa-021187	Canis familiaris	89.70	0.00e+00	2652.00
IUUC-Cpo-022444	Cavia porcellus	89.84	0.00e+00	2654.00
IUUC-Csa-023852	Chlorocebus sabaeus	90.01	0.00e+00	2670.00
IUUC-Csv-026158	Ciona savignyi	58.14	4.00e-177	615.00
IUUC-Dre-027839	Danio rerio	73.66	0.00e+00	1409.00
IUUC-Dno-030058	Dasypus novemcinctus	87.33	0.00e+00	2629.00
IUUC-Dor-030673	Dipodomys ordii	86.61	0.00e+00	2472.00
IUUC-Ete-032705	Echinops telfairi	79.81	0.00e+00	846.00
IUUC-Eca-033885	Equus caballus	88.89	0.00e+00	2598.00
IUUC-Eeu-035338	Erinaceus europaeus	78.05	0.00e+00	2074.00
IUUC-Fca-035388	Felis catus	89.33	0.00e+00	2480.00
IUUC-Fal-037044	Ficedula albicollis	85.67	0.00e+00	2654.00
IUUC-Gmo-039034	Gadus morhua	66.07	0.00e+00	1192.00
IUUC-Gac-041328	Gasterosteus aculeatus	73.06	0.00e+00	2233.00
IUUC-Ggo-045392	Gorilla gorilla	89.38	0.00e+00	2648.00
IUUC-Hsa-046713	Homo sapiens	89.94	0.00e+00	2669.00
IUUC-Itr-049068	Ictidomys tridecemlineatus	92.07	0.00e+00	1544.00
IUUC-Loc-052703	Lepisosteus oculatus	78.65	0.00e+00	2388.00
IUUC-Laf-054193	Loxodonta africana	80.98	0.00e+00	2386.00
IUUC-Mcc-055484	Macaca mulatta	88.83	0.00e+00	2648.00
IUUC-Meu-056278	Macropus eugenii	89.78	0.00e+00	1218.00
IUUC-Mga-059816	Meleagris gallopavo	83.91	0.00e+00	2546.00
IUUC-Mmr-061071	Microcebus murinus	87.25	0.00e+00	2583.00
IUUC-Mdo-062845	Monodelphis domestica	93.18	0.00e+00	2784.00
IUUC-Mmu-063967	Mus musculus	90.64	0.00e+00	2618.00
IUUC-Mpu-066448	Mustela putorius furo	88.21	0.00e+00	2626.00
IUUC-Nle-070037	Nomascus leucogenys	87.46	0.00e+00	2034.00
IUUC-Opr-070325	Ochotona princeps	85.33	0.00e+00	2493.00
IUUC-Ont-071851	Oreochromis niloticus	73.07	0.00e+00	2224.00
IUUC-Oan-073615	Ornithorhynchus anatinus	88.88	0.00e+00	2461.00
IUUC-Ocu-073855	Oryctolagus cuniculus	89.27	0.00e+00	2615.00
IUUC-Ola-086703	Oryzias latipes	72.54	0.00e+00	2212.00
IUUC-Oga-088171	Otolemur garnettii	89.21	0.00e+00	2667.00
IUUC-Oar-089693	Ovis aries	76.32	0.00e+00	1167.00
IUUC-Ptr-090535	Pan troglodytes	90.53	0.00e+00	1659.00
IUUC-Pan-091917	Papio anubis	90.96	0.00e+00	2509.00
IUUC-Psi-093752	Pelodiscus sinensis	77.96	0.00e+00	1356.00
IUUC-Pfo-096827	Poecilia formosa	70.11	0.00e+00	1350.00
IUUC-Pab-098441	Pongo abelii	90.56	0.00e+00	2679.00
IUUC-Pca-100781	Procavia capensis	91.83	0.00e+00	875.00
IUUC-Pva-103099	Pteropus vampyrus	87.47	0.00e+00	1285.00
IUUC-Rno-105872	Rattus norvegicus	90.20	0.00e+00	2650.00
IUUC-Ssc-115638	Sus scrofa	89.60	0.00e+00	2362.00
IUUC-Tgu-116504	Taeniopygia guttata	83.59	0.00e+00	1642.00
IUUC-Tru-118242	Takifugu rubripes	72.25	0.00e+00	1419.00
IUUC-Ttr-128824	Tursiops truncatus	84.57	0.00e+00	2076.00
IUUC-Xtr-131798	Xenopus tropicalis	64.09	0.00e+00	1141.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence