iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000002066.1	ENSSHAT00000002355.1	ENSSHAP00000002331.1
ENSSHAG00000002066.1	ENSSHAT00000002356.1	ENSSHAP00000002332.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.60e-08	35.1	12	53
UBD/SH3	3.90e-31	107.0	385	441

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++C+e ++   +vlpC+H+f++ Clq++     +++ke rCP Cr
   Q: 12   CPVCFEKLDVTAKVLPCQHTFCKPCLQRI----FKTRKELRCPECR 53
           ********88899****************....99**********8 PP

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           + + + ++y+a+  deL l+kG+ ++vi   +  egWlkgv+  +g+ G+fP+++v+ +
   Q: 385  NMFVAVHSYSAKGPDELDLQKGEGIRVI--GKYHEGWLKGVSLVTGRVGIFPKDYVVPI 441
           57889***********************..78889*********************876 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MDDLALLDLL ECPVCFEKLD VTAKVLPCQH TFCKPCLQRI FKTRKELRCP ECRTLVFCSI 60
EELPANLLLV RLLDGVRSGQ SMVRVGSFRR PGVLTSQDSR RKSRTEPRSS QPSPYRLIPN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATGATT TGGCGTTACT TGATCTTCTG GAGTGTCCTG TGTGTTTTGA AAAGCTCGAT 60
GTCACAGCCA AAGTCCTCCC CTGCCAGCAC ACCTTTTGTA AACCATGTCT ACAGAGGATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011511--SH3_2
IPR001452--SH3_domain
IPR028511--SH3RF2
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF07653--SH3_2
PF14604--SH3_9
PF00097--zf-C3HC4

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008270--F:zinc ion binding
GO:0010923--P:negative regulation of phosphatase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001594	Ailuropoda melanoleuca	69.32	0.00e+00	863.00
IUUC-Apl-003443	Anas platyrhynchos	56.44	9.00e-173	600.00
IUUC-Aca-004632	Anolis carolinensis	53.22	8.00e-173	600.00
IUUC-Afl-008572	Aspergillus flavus	39.34	3.00e-09	52.80
IUUC-Bta-013400	Bos taurus	69.53	0.00e+00	852.00
IUUC-Cja-019686	Callithrix jacchus	61.06	0.00e+00	731.00
IUUC-Cfa-020893	Canis familiaris	69.27	0.00e+00	851.00
IUUC-Cpo-021638	Cavia porcellus	65.92	0.00e+00	828.00
IUUC-Csa-023846	Chlorocebus sabaeus	68.79	0.00e+00	880.00
IUUC-Cho-024609	Choloepus hoffmanni	73.49	1.00e-147	516.00
IUUC-Cme-027278	Cyanidioschyzon merolae	44.19	2.00e-07	51.20
IUUC-Dno-028940	Dasypus novemcinctus	66.48	0.00e+00	862.00
IUUC-Dor-030491	Dipodomys ordii	84.10	4.00e-105	375.00
IUUC-Dse-031414	Dothistroma septosporum	36.36	3.00e-08	54.30
IUUC-Ete-032513	Echinops telfairi	68.59	0.00e+00	877.00
IUUC-Eca-034241	Equus caballus	69.09	0.00e+00	907.00
IUUC-Eeu-034636	Erinaceus europaeus	64.11	0.00e+00	731.00
IUUC-Fca-035862	Felis catus	68.98	0.00e+00	867.00
IUUC-Fox-038057	Fusarium oxysporum	30.36	4.00e-09	57.00
IUUC-Gga-040748	Gallus gallus	48.78	5.00e-144	504.00
IUUC-Ggo-045267	Gorilla gorilla	68.35	0.00e+00	845.00
IUUC-Hsa-045761	Homo sapiens	67.93	0.00e+00	840.00
IUUC-Itr-048226	Ictidomys tridecemlineatus	67.69	0.00e+00	838.00
IUUC-Lch-050498	Latimeria chalumnae	43.05	6.00e-123	434.00
IUUC-Laf-054061	Loxodonta africana	59.34	7.00e-178	616.00
IUUC-Mcc-054746	Macaca mulatta	68.35	0.00e+00	839.00
IUUC-Meu-056390	Macropus eugenii	69.47	4.00e-114	405.00
IUUC-Mmr-061390	Microcebus murinus	63.78	0.00e+00	668.00
IUUC-Mdo-062951	Monodelphis domestica	80.14	0.00e+00	1122.00
IUUC-Mmu-063840	Mus musculus	65.69	0.00e+00	835.00
IUUC-Mpu-065840	Mustela putorius furo	68.30	0.00e+00	884.00
IUUC-Mlu-067378	Myotis lucifugus	68.30	0.00e+00	828.00
IUUC-Nle-069535	Nomascus leucogenys	66.39	0.00e+00	802.00
IUUC-Opr-070739	Ochotona princeps	66.10	0.00e+00	828.00
IUUC-Oan-073468	Ornithorhynchus anatinus	65.97	0.00e+00	806.00
IUUC-Ocu-074343	Oryctolagus cuniculus	66.25	0.00e+00	805.00
IUUC-Oga-088276	Otolemur garnettii	61.88	0.00e+00	756.00
IUUC-Oar-090315	Ovis aries	68.97	0.00e+00	854.00
IUUC-Ptr-091119	Pan troglodytes	67.93	0.00e+00	840.00
IUUC-Pan-092158	Papio anubis	71.81	0.00e+00	676.00
IUUC-Psi-092959	Pelodiscus sinensis	58.83	0.00e+00	724.00
IUUC-Pab-097675	Pongo abelii	68.50	0.00e+00	845.00
IUUC-Pca-101021	Procavia capensis	60.81	0.00e+00	738.00
IUUC-Pva-102619	Pteropus vampyrus	69.68	0.00e+00	864.00
IUUC-Rno-105918	Rattus norvegicus	65.45	0.00e+00	827.00
IUUC-Sar-113148	Sorex araneus	70.64	4.00e-163	568.00
IUUC-Tgu-116584	Taeniopygia guttata	63.46	3.00e-74	271.00
IUUC-Tsy-118968	Tarsius syrichta	69.50	1.00e-137	483.00
IUUC-Tbe-128007	Tupaia belangeri	72.34	0.00e+00	659.00
IUUC-Ttr-128499	Tursiops truncatus	68.95	0.00e+00	889.00
IUUC-Vpa-130075	Vicugna pacos	88.52	4.00e-67	249.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence