iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-14	54.4	595	625

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWD 29
           gHtd+ ++l+    + ++++++++D ++ +WD
   Q: 595  GHTDELWGLCThpfQ-NRFLTCGHDRQLCLWD 625
           8*******9877543.89************** PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MDGTAGPGEG PAHETLQTLS QRLRVQEEEM ELVKAALAEA LRLLRLHGPT TTLQGSGISA 60
PTRNSITVPP GLPPTCSPSL VSRGTQTEGG LEMEPISGPP GLSNGPPALQ GGSEEPSGTQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGTAAGAGG CCCAGCTCCA CAGCGCCCCC TCCAATTCCT GTCCCCACGC TCGACGGCGC 60
CCCCGAGGGG TGGCACTGCT CCTCTCCGCG CGCGCCCTGG TGCTTCCTTC CCCTCTCCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0015630--C:microtubule cytoskeleton
GO:0008017--F:microtubule binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002054	Ailuropoda melanoleuca	87.99	0.00e+00	1128.00
IUUC-Ame-011151	Astyanax mexicanus	66.02	0.00e+00	935.00
IUUC-Bta-012809	Bos taurus	91.68	0.00e+00	1345.00
IUUC-Cja-019497	Callithrix jacchus	92.76	0.00e+00	1388.00
IUUC-Cfa-020836	Canis familiaris	90.60	0.00e+00	1368.00
IUUC-Cpo-021285	Cavia porcellus	93.31	0.00e+00	1325.00
IUUC-Csa-023442	Chlorocebus sabaeus	93.21	0.00e+00	1395.00
IUUC-Cho-024509	Choloepus hoffmanni	87.60	5.00e-126	444.00
IUUC-Dre-027697	Danio rerio	66.48	0.00e+00	1014.00
IUUC-Dno-029179	Dasypus novemcinctus	89.60	0.00e+00	1354.00
IUUC-Dor-030271	Dipodomys ordii	92.69	0.00e+00	1383.00
IUUC-Eca-033995	Equus caballus	93.98	0.00e+00	1391.00
IUUC-Eeu-034661	Erinaceus europaeus	87.25	1.00e-142	500.00
IUUC-Fca-036507	Felis catus	91.32	0.00e+00	1386.00
IUUC-Gmo-038631	Gadus morhua	66.26	0.00e+00	889.00
IUUC-Gga-041067	Gallus gallus	73.26	0.00e+00	972.00
IUUC-Gac-042487	Gasterosteus aculeatus	63.57	0.00e+00	882.00
IUUC-Ggo-044578	Gorilla gorilla	95.35	0.00e+00	1291.00
IUUC-Hsa-045907	Homo sapiens	93.01	0.00e+00	1226.00
IUUC-Itr-047963	Ictidomys tridecemlineatus	93.53	0.00e+00	1456.00
IUUC-Lch-049525	Latimeria chalumnae	65.61	0.00e+00	899.00
IUUC-Laf-054051	Loxodonta africana	90.18	0.00e+00	1442.00
IUUC-Mcc-055534	Macaca mulatta	92.86	0.00e+00	1225.00
IUUC-Meu-056318	Macropus eugenii	87.01	0.00e+00	1076.00
IUUC-Mmr-060972	Microcebus murinus	92.60	0.00e+00	1206.00
IUUC-Mdo-062421	Monodelphis domestica	87.56	0.00e+00	1241.00
IUUC-Mmu-064240	Mus musculus	98.22	0.00e+00	1509.00
IUUC-Mpu-065950	Mustela putorius furo	92.98	0.00e+00	1363.00
IUUC-Mlu-067823	Myotis lucifugus	88.95	0.00e+00	1139.00
IUUC-Nle-069939	Nomascus leucogenys	92.28	0.00e+00	1381.00
IUUC-Opr-070593	Ochotona princeps	90.47	0.00e+00	1243.00
IUUC-Ont-072032	Oreochromis niloticus	66.86	0.00e+00	986.00
IUUC-Oan-073228	Ornithorhynchus anatinus	90.32	0.00e+00	1187.00
IUUC-Ocu-074660	Oryctolagus cuniculus	92.36	0.00e+00	1362.00
IUUC-Ola-087269	Oryzias latipes	55.25	0.00e+00	957.00
IUUC-Oga-088749	Otolemur garnettii	92.49	0.00e+00	1223.00
IUUC-Oar-090190	Ovis aries	90.53	0.00e+00	1368.00
IUUC-Pan-091858	Papio anubis	93.22	0.00e+00	1396.00
IUUC-Psi-093997	Pelodiscus sinensis	76.66	0.00e+00	1078.00
IUUC-Pfo-096045	Poecilia formosa	64.81	0.00e+00	949.00
IUUC-Pab-098492	Pongo abelii	93.58	0.00e+00	1368.00
IUUC-Pca-100221	Procavia capensis	84.46	0.00e+00	1324.00
IUUC-Pva-103024	Pteropus vampyrus	88.93	0.00e+00	1361.00
IUUC-Sha-106886	Sarcophilus harrisii	89.23	0.00e+00	1031.00
IUUC-Ssc-116107	Sus scrofa	92.86	0.00e+00	1403.00
IUUC-Ttr-128375	Tursiops truncatus	86.90	0.00e+00	1234.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence