iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-090590

Ensembl Protein ID

ENSPTRP00000032533.2

UniProt Accession

H2QUD1; H2QUD1_PANTR

Genbank Protein ID

JAA02448.1; JAA20711.1; JAA24917.1; JAA35085.1

Protein Name

Nucleotide-binding oligomerization domain containing 1

Genbank Nucleotide ID

AC091716; GABF01001434; GABD01008183; GABE01009654

Gene Name

NOD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000019040.2	ENSPTRT00000035193.2	ENSPTRP00000032533.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/CARD	99.58	0.00e+00	1825.00	IUUC-Hsa-046886

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MEEQGHSEME IIPSESHPHI QLLKSNRELL VTHIRNTQCL VDNLLKNDYF SAEDAEIVCA 60
CPTQPDKVRK ILDLVQSKGE EVSEFFLYLL QQLADAYVDL RPWLLEIGFS PSLLTQSKVV 120

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Nucleotide Sequence
(Fasta)

GTTCCGGGCC CGCGAGGCGG CCACCCCGGT CCTGCCCCTC CCTCGCGCTA CTGCGGGAGC 60
AGCGTCCTCC CGGGCCACGG CGCTTCCCGG CCCCGGCGTC CCCGGACCAT GGCGCTCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001315--CARD
IPR011029--DEATH-like_dom
IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR007111--NACHT_NTPase

PROSITE

PS50209--CARD
PS50837--NACHT

Pfam

PF00619--CARD
PF13516--LRR_6

Gene Ontology

GO:0016323--C:basolateral plasma membrane
GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0071225--P:cellular response to muramyl dipeptide
GO:0050830--P:defense response to Gram-positive bacterium
GO:0016045--P:detection of bacterium
GO:0042228--P:interleukin-8 biosynthetic process
GO:0035556--P:intracellular signal transduction
GO:0002606--P:positive regulation of dendritic cell antigen processing and presentation
GO:0070374--P:positive regulation of ERK1 and ERK2 cascade
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032755--P:positive regulation of interleukin-6 production
GO:0046330--P:positive regulation of JNK cascade
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:1901224--P:positive regulation of NIK/NF-kappaB signaling
GO:0032760--P:positive regulation of tumor necrosis factor production
GO:1904417--P:positive regulation of xenophagy

KEGG

ptr:472336

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001299	Ailuropoda melanoleuca	82.58	0.00e+00	1410.00
IUUC-Apl-003908	Anas platyrhynchos	61.90	0.00e+00	1145.00
IUUC-Aca-005144	Anolis carolinensis	60.71	0.00e+00	1123.00
IUUC-Ame-010829	Astyanax mexicanus	51.37	0.00e+00	898.00
IUUC-Bta-013358	Bos taurus	83.12	0.00e+00	1486.00
IUUC-Cja-019392	Callithrix jacchus	93.60	0.00e+00	1693.00
IUUC-Cfa-020776	Canis familiaris	83.63	0.00e+00	1470.00
IUUC-Cpo-021393	Cavia porcellus	79.56	0.00e+00	1463.00
IUUC-Csa-023872	Chlorocebus sabaeus	96.64	0.00e+00	1773.00
IUUC-Cho-024569	Choloepus hoffmanni	73.89	2.00e-180	626.00
IUUC-Dre-027478	Danio rerio	51.17	0.00e+00	882.00
IUUC-Dno-029231	Dasypus novemcinctus	83.53	0.00e+00	1524.00
IUUC-Dor-030251	Dipodomys ordii	57.55	2.00e-156	546.00
IUUC-Ete-032484	Echinops telfairi	72.94	0.00e+00	774.00
IUUC-Eca-033564	Equus caballus	86.12	0.00e+00	1550.00
IUUC-Eeu-034456	Erinaceus europaeus	66.75	3.00e-142	498.00
IUUC-Fca-036372	Felis catus	82.79	0.00e+00	1479.00
IUUC-Fal-037418	Ficedula albicollis	62.42	0.00e+00	1138.00
IUUC-Gmo-038740	Gadus morhua	51.02	0.00e+00	897.00
IUUC-Gga-040775	Gallus gallus	62.42	0.00e+00	1175.00
IUUC-Gac-041612	Gasterosteus aculeatus	49.69	0.00e+00	899.00
IUUC-Ggo-045161	Gorilla gorilla	99.63	0.00e+00	1550.00
IUUC-Hsa-046886	Homo sapiens	99.58	0.00e+00	1825.00
IUUC-Itr-048414	Ictidomys tridecemlineatus	85.59	0.00e+00	1629.00
IUUC-Lch-049764	Latimeria chalumnae	58.90	0.00e+00	1014.00
IUUC-Loc-052143	Lepisosteus oculatus	54.20	0.00e+00	998.00
IUUC-Laf-053503	Loxodonta africana	82.98	0.00e+00	1515.00
IUUC-Mcc-054992	Macaca mulatta	96.01	0.00e+00	1763.00
IUUC-Meu-056406	Macropus eugenii	62.65	0.00e+00	1103.00
IUUC-Mga-059351	Meleagris gallopavo	61.78	0.00e+00	1169.00
IUUC-Mmr-061537	Microcebus murinus	85.94	0.00e+00	1493.00
IUUC-Mdo-061832	Monodelphis domestica	64.87	0.00e+00	1075.00
IUUC-Mmu-064282	Mus musculus	81.53	0.00e+00	1494.00
IUUC-Mpu-066399	Mustela putorius furo	84.05	0.00e+00	1506.00
IUUC-Mlu-067265	Myotis lucifugus	81.41	0.00e+00	1440.00
IUUC-Nle-069078	Nomascus leucogenys	96.75	0.00e+00	1768.00
IUUC-Opr-070946	Ochotona princeps	74.77	0.00e+00	1358.00
IUUC-Ont-071355	Oreochromis niloticus	49.27	0.00e+00	902.00
IUUC-Oan-072937	Ornithorhynchus anatinus	73.67	0.00e+00	1360.00
IUUC-Ocu-073815	Oryctolagus cuniculus	81.64	0.00e+00	1538.00
IUUC-Ola-087381	Oryzias latipes	49.41	0.00e+00	872.00
IUUC-Oga-088725	Otolemur garnettii	85.31	0.00e+00	1570.00
IUUC-Oar-090401	Ovis aries	80.82	0.00e+00	1499.00
IUUC-Pan-091765	Papio anubis	96.33	0.00e+00	1766.00
IUUC-Psi-093182	Pelodiscus sinensis	62.00	0.00e+00	1159.00
IUUC-Pfo-097422	Poecilia formosa	48.98	0.00e+00	876.00
IUUC-Pab-098289	Pongo abelii	97.80	0.00e+00	1781.00
IUUC-Pca-100165	Procavia capensis	73.29	0.00e+00	1021.00
IUUC-Pva-102943	Pteropus vampyrus	84.99	0.00e+00	1539.00
IUUC-Rno-104930	Rattus norvegicus	81.43	0.00e+00	1518.00
IUUC-Sha-106800	Sarcophilus harrisii	50.00	0.00e+00	798.00
IUUC-Sar-113205	Sorex araneus	70.79	0.00e+00	982.00
IUUC-Ssc-115910	Sus scrofa	83.31	0.00e+00	1313.00
IUUC-Tgu-117179	Taeniopygia guttata	63.17	0.00e+00	1155.00
IUUC-Tru-118220	Takifugu rubripes	48.23	0.00e+00	849.00
IUUC-Tsy-119418	Tarsius syrichta	83.92	0.00e+00	1247.00
IUUC-Tni-120033	Tetraodon nigroviridis	51.99	1.00e-71	263.00
IUUC-Tbe-127308	Tupaia belangeri	85.83	0.00e+00	629.00
IUUC-Ttr-129233	Tursiops truncatus	83.00	0.00e+00	1499.00
IUUC-Vpa-130620	Vicugna pacos	81.27	3.00e-111	396.00
IUUC-Xtr-132075	Xenopus tropicalis	52.89	0.00e+00	993.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence