iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000014290.5	ENSGALT00000023108.4	ENSGALP00000023065.3
ENSGALG00000014290.5	ENSGALT00000086806.1	ENSGALP00000058907.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	4.50e-46	156.4	8	146
UBD/Alpha-Helix/UBA	1.00e-10	41.8	161	199
UBD/UBC-like/UBD_UBC	7.20e-73	243.5	8	149

Active Site

Position(s)	Description	Evidence
92	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    Rlkkelkel...ekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsi 85
           R+k+e+ke+   e++++++i++++vde ++te++ +i Gp+dtpYegg ++lei++pe+YPf+PPkv+f+tki+hPn+++  G++Cl+i
   Q: 8    RIKREFKEVlksEETSKNQIKVDLVDE-NFTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVtGAICLDI 95
           7888888873335556699********.9***************************************************99******* PP
   S: 86   lkeeekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           lk  ++W +a+++++vlls+q+lla ++p++p+++ +a+++k+n+e++k+++r
   Q: 96   LK--DQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTAR 146
           *9..**********************************************986 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMGFdreealqaLraannnleaAveyLld 40
           e++ k+e+l++MGFdr++++ aL + ++++e A+e+Ll+
   Q: 161  EYTRKIENLCAMGFDRNAVIVALSSKSWDVETATELLLS 199
           5788*********************************97 PP

UBD/UBC-like/UBD_UBC

   S: 1    rikkelkdllrdeea...qisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpnins.ngsicldil 85
           rik+e+k++l++ee+   qi++dlvd++++elr++iagppd+pyegg+++l+ik+p++ypf+ppkv+fitki+hpni+s +g+icldil
   Q: 8    RIKREFKEVLKSEETsknQIKVDLVDENFTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSvTGAICLDIL 96
           8*************9999*********************************************************************** PP
   S: 86   rsqwsaaltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           ++qw+aa+tl++vllsl++lla+aepddp++a++a++yk+++e++k++ar+w+
   Q: 97   KDQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTARLWA 149
           ****************************************************7 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MANIAVQRIK REFKEVLKSE ETSKNQIKVD LVDENFTELR GEIAGPPDTP YEGGRYQLEI 60
KIPETYPFNP PKVRFITKIW HPNISSVTGA ICLDILKDQW AAAMTLRTVL LSLQALLAAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CATTTTGGTG GGGCCGGGAG TTATCCAGCG GGAGCGGCGG CGGCGGAGCT CGCTGGGCCC 60
GGCTCGGAGG TGGCGGCGAG TGCGCGCTCG CTGCGGAGAT GGCCAACATC GCGGTGCAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50030--UBA
PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00627--UBA
PF00179--UQ_con

SMART

SM00165--UBA

Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0032433--C:filopodium tip
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0035458--P:cellular response to interferon-beta
GO:0010994--P:free ubiquitin chain polymerization
GO:0010800--P:positive regulation of peptidyl-threonine phosphorylation
GO:0060340--P:positive regulation of type I interferon-mediated signaling pathway
GO:0070936--P:protein K48-linked ubiquitination
GO:0032434--P:regulation of proteasomal ubiquitin-dependent protein catabolic process

KEGG

gga:428787

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000621	Aegilops tauschii	51.55	3.00e-28	117.00
IUUC-Aml-001286	Ailuropoda melanoleuca	99.50	9.00e-110	388.00
IUUC-Atr-003063	Amborella trichopoda	47.94	1.00e-39	155.00
IUUC-Apl-004122	Anas platyrhynchos	92.00	4.00e-97	346.00
IUUC-Aca-004565	Anolis carolinensis	94.21	5.00e-99	352.00
IUUC-Aly-006390	Arabidopsis lyrata	47.72	5.00e-44	170.00
IUUC-Ath-006637	Arabidopsis thaliana	46.86	3.00e-41	161.00
IUUC-Ago-007714	Ashbya gossypii	44.62	6.00e-38	150.00
IUUC-Acl-008189	Aspergillus clavatus	49.68	6.00e-28	117.00
IUUC-Afl-008489	Aspergillus flavus	41.40	4.00e-28	117.00
IUUC-Afu-008850	Aspergillus fumigatus	40.65	6.00e-29	120.00
IUUC-Ani-009361	Aspergillus nidulans	50.68	1.00e-26	113.00
IUUC-Ang-009548	Aspergillus niger	48.39	2.00e-26	112.00
IUUC-Aor-010105	Aspergillus oryzae	41.40	4.00e-28	117.00
IUUC-Ate-010389	Aspergillus terreus	40.55	4.00e-28	117.00
IUUC-Ame-011454	Astyanax mexicanus	97.50	5.00e-108	382.00
IUUC-Bgr-012255	Blumeria graminis	48.41	7.00e-34	137.00
IUUC-Bta-012992	Bos taurus	99.50	9.00e-110	388.00
IUUC-Bci-013806	Botrytis cinerea	40.09	3.00e-36	144.00
IUUC-Bdi-015024	Brachypodium distachyon	48.22	1.00e-40	158.00
IUUC-Bol-015985	Brassica oleracea	48.22	1.00e-44	172.00
IUUC-Bra-016805	Brassica rapa	48.22	7.00e-45	172.00
IUUC-Cel-018353	Caenorhabditis elegans	52.26	1.00e-56	212.00
IUUC-Cja-019051	Callithrix jacchus	99.00	7.00e-109	385.00
IUUC-Cfa-020016	Canis familiaris	99.50	9.00e-110	388.00
IUUC-Cpo-022026	Cavia porcellus	99.50	9.00e-110	388.00
IUUC-Cre-022987	Chlamydomonas reinhardtii	48.98	7.00e-42	162.00
IUUC-Csa-023059	Chlorocebus sabaeus	99.50	9.00e-110	388.00
IUUC-Cho-024276	Choloepus hoffmanni	95.92	2.00e-73	267.00
IUUC-Cin-025598	Ciona intestinalis	60.71	4.00e-56	210.00
IUUC-Csv-025831	Ciona savignyi	62.24	2.00e-54	204.00
IUUC-Cgl-026449	Colletotrichum gloeosporioides	43.90	3.00e-34	137.00
IUUC-Cne-027068	Cryptococcus neoformans	41.87	1.00e-41	162.00
IUUC-Dre-028139	Danio rerio	97.50	6.00e-108	382.00
IUUC-Dno-029169	Dasypus novemcinctus	93.00	6.00e-102	362.00
IUUC-Dor-030382	Dipodomys ordii	85.50	3.00e-88	317.00
IUUC-Dse-031335	Dothistroma septosporum	50.96	6.00e-37	147.00
IUUC-Dme-032003	Drosophila melanogaster	68.34	2.00e-71	261.00
IUUC-Ete-032868	Echinops telfairi	90.50	3.00e-88	317.00
IUUC-Eca-033428	Equus caballus	99.50	9.00e-110	388.00
IUUC-Eeu-035103	Erinaceus europaeus	72.66	5.00e-49	185.00
IUUC-Fca-035366	Felis catus	99.50	9.00e-110	388.00
IUUC-Fal-037016	Ficedula albicollis	99.50	9.00e-110	388.00
IUUC-Fox-037969	Fusarium oxysporum	42.08	6.00e-34	137.00
IUUC-Fso-038296	Fusarium solani	44.26	6.00e-36	143.00
IUUC-Gmo-039135	Gadus morhua	96.50	1.00e-106	377.00
IUUC-Ggr-039768	Gaeumannomyces graminis	46.25	7.00e-26	110.00
IUUC-Gac-041503	Gasterosteus aculeatus	97.00	2.00e-107	380.00
IUUC-Gma-042779	Glycine max	50.26	3.00e-43	167.00
IUUC-Ggo-045032	Gorilla gorilla	99.50	9.00e-110	388.00
IUUC-Hsa-046490	Homo sapiens	99.50	9.00e-110	388.00
IUUC-Itr-048373	Ictidomys tridecemlineatus	99.50	9.00e-110	388.00
IUUC-Kpa-049297	Komagataella pastoris	49.02	6.00e-34	137.00
IUUC-Lch-050588	Latimeria chalumnae	68.72	2.00e-76	278.00
IUUC-Lpe-051070	Leersia perrieri	48.22	1.00e-32	132.00
IUUC-Loc-052549	Lepisosteus oculatus	98.00	2.00e-108	384.00
IUUC-Lma-052949	Leptosphaeria maculans	49.36	6.00e-37	147.00
IUUC-Laf-053688	Loxodonta africana	91.67	6.00e-100	355.00
IUUC-Mcc-055606	Macaca mulatta	99.50	9.00e-110	388.00
IUUC-Mor-056946	Magnaporthe oryzae	37.93	3.00e-23	101.00
IUUC-Mpo-057441	Magnaporthe poae	46.47	6.00e-26	110.00
IUUC-Mtr-058002	Medicago truncatula	49.74	8.00e-43	166.00
IUUC-Mla-059007	Melampsora laricipopulina	43.52	9.00e-38	149.00
IUUC-Mga-059254	Meleagris gallopavo	99.44	5.00e-98	349.00
IUUC-Mvi-060346	Microbotryum violaceum	41.50	1.00e-33	135.00
IUUC-Mmr-061211	Microcebus murinus	99.50	9.00e-110	388.00
IUUC-Mdo-062458	Monodelphis domestica	98.50	3.00e-107	380.00
IUUC-Mmu-063648	Mus musculus	99.50	9.00e-110	388.00
IUUC-Mac-065447	Musa acuminata	48.22	5.00e-41	160.00
IUUC-Mpu-066407	Mustela putorius furo	99.50	4.00e-109	386.00
IUUC-Mlu-067682	Myotis lucifugus	92.42	4.00e-100	356.00
IUUC-Nfi-068517	Neosartorya fischeri	41.12	4.00e-29	120.00
IUUC-Ncr-068749	Neurospora crassa	48.08	2.00e-38	152.00
IUUC-Nle-069712	Nomascus leucogenys	99.44	4.00e-98	350.00
IUUC-Opr-070651	Ochotona princeps	99.50	9.00e-110	388.00
IUUC-Ont-071433	Oreochromis niloticus	97.00	2.00e-107	381.00
IUUC-Oan-073058	Ornithorhynchus anatinus	99.32	1.00e-78	284.00
IUUC-Ocu-074939	Oryctolagus cuniculus	99.50	9.00e-110	388.00
IUUC-Oba-075530	Oryza barthii	48.99	8.00e-32	129.00
IUUC-Obr-076838	Oryza brachyantha	48.48	3.00e-31	127.00
IUUC-Ogl-077606	Oryza glaberrima	48.99	8.00e-32	129.00
IUUC-Ogu-078238	Oryza glumaepatula	48.99	8.00e-32	129.00
IUUC-Oin-079643	Oryza indica	48.99	2.00e-31	128.00
IUUC-Ome-081274	Oryza meridionalis	48.99	8.00e-32	129.00
IUUC-Oni-082651	Oryza nivara	48.99	8.00e-32	129.00
IUUC-Opu-083933	Oryza punctata	48.99	2.00e-31	128.00
IUUC-Oru-085054	Oryza rufipogon	48.99	2.00e-31	128.00
IUUC-Osa-085716	Oryza sativa	48.99	2.00e-31	128.00
IUUC-Ola-087043	Oryzias latipes	97.00	2.00e-107	380.00
IUUC-Olu-087846	Ostreococcus lucimarinus	46.63	6.00e-42	163.00
IUUC-Oga-088897	Otolemur garnettii	93.43	4.00e-100	356.00
IUUC-Oar-089673	Ovis aries	92.42	2.00e-100	357.00
IUUC-Ptr-091295	Pan troglodytes	99.50	9.00e-110	388.00
IUUC-Pan-092034	Papio anubis	99.44	2.00e-97	347.00
IUUC-Psi-093498	Pelodiscus sinensis	99.50	9.00e-110	388.00
IUUC-Pma-094115	Petromyzon marinus	83.42	7.00e-90	322.00
IUUC-Pno-095102	Phaeosphaeria nodorum	40.28	1.00e-37	149.00
IUUC-Ppa-095326	Physcomitrella patens	46.19	7.00e-40	156.00
IUUC-Pfo-096940	Poecilia formosa	97.00	2.00e-107	381.00
IUUC-Pab-098279	Pongo abelii	99.50	9.00e-110	388.00
IUUC-Pop-099543	Populus trichocarpa	49.24	3.00e-44	171.00
IUUC-Pca-100782	Procavia capensis	99.00	9.00e-108	381.00
IUUC-Ppe-101789	Prunus persica	47.94	4.00e-37	147.00
IUUC-Pva-102147	Pteropus vampyrus	70.45	1.00e-57	215.00
IUUC-Pgr-103643	Puccinia graminis	46.75	9.00e-38	150.00
IUUC-Ptt-103772	Puccinia triticina	47.95	2.00e-36	145.00
IUUC-Pte-104370	Pyrenophora teres	49.36	9.00e-37	146.00
IUUC-Pyt-104592	Pyrenophora triticirepentis	49.36	1.00e-36	145.00
IUUC-Rno-104984	Rattus norvegicus	99.50	9.00e-110	388.00
IUUC-Sce-106394	Saccharomyces cerevisiae	43.01	3.00e-35	140.00
IUUC-Sha-106624	Sarcophilus harrisii	93.00	1.00e-103	368.00
IUUC-Ssl-108609	Sclerotinia sclerotiorum	42.86	1.00e-40	159.00
IUUC-Smo-109656	Selaginella moellendorffii	48.47	3.00e-40	157.00
IUUC-Sit-110639	Setaria italica	47.98	2.00e-39	154.00
IUUC-Sly-110978	Solanum lycopersicum	48.22	7.00e-44	169.00
IUUC-Stu-112088	Solanum tuberosum	48.22	3.00e-44	171.00
IUUC-Sar-113285	Sorex araneus	83.80	5.00e-76	276.00
IUUC-Sbi-113986	Sorghum bicolor	47.98	3.00e-39	154.00
IUUC-Ssc-116314	Sus scrofa	99.50	9.00e-110	388.00
IUUC-Tgu-117427	Taeniopygia guttata	98.89	1.00e-97	348.00
IUUC-Tru-118618	Takifugu rubripes	92.00	2.00e-102	364.00
IUUC-Tsy-119208	Tarsius syrichta	97.47	2.00e-106	377.00
IUUC-Tni-119667	Tetraodon nigroviridis	97.50	8.00e-108	382.00
IUUC-Tca-121446	Theobroma cacao	49.75	4.00e-45	173.00
IUUC-Tre-122053	Trichoderma reesei	36.82	2.00e-31	129.00
IUUC-Tvi-122533	Trichoderma virens	37.31	5.00e-31	127.00
IUUC-Tae-124726	Triticum aestivum	48.73	2.00e-33	134.00
IUUC-Tme-127024	Tuber melanosporum	50.97	3.00e-39	154.00
IUUC-Tbe-127752	Tupaia belangeri	96.00	1.00e-104	371.00
IUUC-Ttr-128287	Tursiops truncatus	99.44	1.00e-97	347.00
IUUC-Vda-129947	Verticillium dahliae	37.20	2.00e-31	128.00
IUUC-Vpa-130481	Vicugna pacos	99.49	1.00e-107	381.00
IUUC-Vvi-131429	Vitis vinifera	46.19	3.00e-41	160.00
IUUC-Xtr-132710	Xenopus tropicalis	82.67	3.00e-95	340.00
IUUC-Xma-134308	Xiphophorus maculatus	96.50	4.00e-107	379.00
IUUC-Yli-134523	Yarrowia lipolytica	42.78	5.00e-34	137.00
IUUC-Zma-135733	Zea mays	47.14	1.00e-37	149.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence