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Tag Content
UUCD2 ID IUUC-Cpo-021743
UUCD1 version UUC-CaP-00591
Ensembl Protein ID ENSCPOP00000011806.2
UniProt Accession H0VN00; H0VN00_CAVPO
Genbank Protein ID ENSCPOP00000011806
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAKN02033115
Gene Name NLE1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCPOG00000013116.3 ENSCPOT00000013243.2 ENSCPOP00000011806.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.20e-66 217.5 197 240
UBD/Beta-Prp 2.80e-78 263.1 106 304
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf......sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH+ ++t+l++      ++ ++++s+s Dg+++vWD+++g++++
   Q: 197  GHSKWITGLSWeplhvnPEcRYVASSSKDGSVRVWDTTSGRCER 240
           8***************9889**********************86 PP
   

   UBD/Beta-Prp
   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleet 132
           + +s++gh+++v +v fsp+gk+l++gs D t++ wdlst ++  t kgh + vls+s+sp+g +l+sG +   i +wd +tg  +  t
   Q: 106  CTSSIEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGRRLASGCKNGQILLWDPSTGNQMGRT 194
           57899************************************************************************************ PP
   S: 133  lsghdgvvncvvv.....hpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvr 216
           l+gh+++++++++     +p++++++s+s+D+ vr+Wd  +g++ r ltg ht+sv++l +  +g  l s+s+d+t+k+w  + g   r
   Q: 195  LTGHSKWITGLSWeplhvNPECRYVASSSKDGSVRVWDTTSGRCERVLTG-HTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCR 281
           *********98652222278899**************************9.************98.*********************** PP
   S: 217  tlnghtdnvksvrfspnderlvsg 240
           tl+gh  +v+ +++s  d  l +g
   Q: 282  TLQGHGHWVNTMALS-TDYALRTG 304
           **************9.44444444 PP
   
Organism Cavia porcellus
Protein Sequence
(Fasta)
MAAEAADEEA AHDVQRLLVQ FQDESGQLLG SPFDVPVDIT PERLQLVCNA LLAQEDPLPL 60
AFYVHDAEIV SSLGKTLESQ AVETEKVVDI IYQPQAIFRV RAVTRCTSSI EGHSEAVISV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cpo-021743|E3,WD_repeat;UBD,Beta-Prp|Cavia porcellus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGCGGCAG AAGCAGCGGT GGGTGTGAGC GGATGGGAAG GGGAGCCACG GCTCGGCGCC 60
AGACCGAGTC CCCGAGGCCG GAGGGAGGCA AAGCGGGGAT CTAACGGTCG GGCGGAGGTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cpo-021743|E3,WD_repeat;UBD,Beta-Prp|Cavia porcellus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR012972--NLE
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08154--NLE
PF00400--WD40
PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0005730--C:nucleolus
GO:0061484--P:hematopoietic stem cell homeostasis
GO:0001826--P:inner cell mass cell differentiation
GO:0001822--P:kidney development
GO:2001268--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
GO:0045930--P:negative regulation of mitotic cell cycle
GO:0007219--P:Notch signaling pathway
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0042273--P:ribosomal large subunit biogenesis
GO:0048705--P:skeletal system morphogenesis
GO:0001756--P:somitogenesis
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000437 Aegilops tauschii 58.80 9.00e-172 596.00
IUUC-Aml-001793 Ailuropoda melanoleuca 94.93 0.00e+00 935.00
IUUC-Atr-002507 Amborella trichopoda 59.06 1.00e-169 588.00
IUUC-Apl-003964 Anas platyrhynchos 83.70 0.00e+00 809.00
IUUC-Aly-006396 Arabidopsis lyrata 54.68 1.00e-161 562.00
IUUC-Ath-007278 Arabidopsis thaliana 54.89 1.00e-161 562.00
IUUC-Ago-007951 Ashbya gossypii 47.85 1.00e-129 456.00
IUUC-Acl-008298 Aspergillus clavatus 47.50 8.00e-121 427.00
IUUC-Afl-008581 Aspergillus flavus 52.37 1.00e-108 386.00
IUUC-Afu-008906 Aspergillus fumigatus 46.49 1.00e-120 426.00
IUUC-Ani-009189 Aspergillus nidulans 45.12 2.00e-117 416.00
IUUC-Ang-009630 Aspergillus niger 48.04 6.00e-124 437.00
IUUC-Aor-010038 Aspergillus oryzae 47.72 2.00e-127 449.00
IUUC-Ate-010278 Aspergillus terreus 47.09 1.00e-122 433.00
IUUC-Ame-011890 Astyanax mexicanus 79.28 0.00e+00 816.00
IUUC-Bgr-012011 Blumeria graminis 48.65 7.00e-132 463.00
IUUC-Bta-012964 Bos taurus 94.71 0.00e+00 934.00
IUUC-Bci-013592 Botrytis cinerea 45.55 2.00e-121 429.00
IUUC-Bdi-015035 Brachypodium distachyon 58.46 7.00e-172 596.00
IUUC-Bol-015501 Brassica oleracea 55.56 1.00e-161 562.00
IUUC-Bra-017642 Brassica rapa 55.34 6.00e-161 560.00
IUUC-Cel-018430 Caenorhabditis elegans 57.94 2.00e-166 578.00
IUUC-Cja-019125 Callithrix jacchus 95.35 0.00e+00 936.00
IUUC-Cfa-021013 Canis familiaris 94.46 0.00e+00 852.00
IUUC-Cre-022973 Chlamydomonas reinhardtii 46.07 5.00e-117 414.00
IUUC-Csa-024270 Chlorocebus sabaeus 95.35 0.00e+00 937.00
IUUC-Cin-025795 Ciona intestinalis 66.52 0.00e+00 690.00
IUUC-Csv-025953 Ciona savignyi 66.74 0.00e+00 684.00
IUUC-Cgl-026517 Colletotrichum gloeosporioides 52.52 1.00e-109 390.00
IUUC-Cne-026901 Cryptococcus neoformans 48.80 9.00e-138 483.00
IUUC-Cme-027281 Cyanidioschyzon merolae 47.60 2.00e-114 406.00
IUUC-Dre-028515 Danio rerio 76.74 0.00e+00 796.00
IUUC-Dno-029596 Dasypus novemcinctus 94.93 0.00e+00 934.00
IUUC-Dor-030494 Dipodomys ordii 95.75 0.00e+00 932.00
IUUC-Dse-031538 Dothistroma septosporum 48.03 5.00e-130 457.00
IUUC-Dme-031974 Drosophila melanogaster 58.26 1.00e-168 586.00
IUUC-Ete-032948 Echinops telfairi 97.61 7.00e-119 420.00
IUUC-Eca-033399 Equus caballus 96.39 0.00e+00 940.00
IUUC-Eeu-035013 Erinaceus europaeus 96.17 2.00e-117 416.00
IUUC-Fca-035860 Felis catus 94.71 0.00e+00 931.00
IUUC-Fal-037069 Ficedula albicollis 87.60 1.00e-131 462.00
IUUC-Fox-038059 Fusarium oxysporum 46.97 2.00e-126 445.00
IUUC-Fso-038445 Fusarium solani 47.18 1.00e-126 446.00
IUUC-Gmo-039319 Gadus morhua 75.11 0.00e+00 731.00
IUUC-Ggr-040095 Gaeumannomyces graminis 47.29 2.00e-122 432.00
IUUC-Gga-040303 Gallus gallus 85.60 4.00e-130 456.00
IUUC-Gac-042267 Gasterosteus aculeatus 77.47 0.00e+00 763.00
IUUC-Gma-043974 Glycine max 57.02 6.00e-170 590.00
IUUC-Ggo-044637 Gorilla gorilla 95.54 0.00e+00 931.00
IUUC-Hsa-046128 Homo sapiens 95.98 0.00e+00 942.00
IUUC-Hvu-047373 Hordeum vulgare 58.24 6.00e-171 593.00
IUUC-Itr-048070 Ictidomys tridecemlineatus 94.77 0.00e+00 936.00
IUUC-Kpa-049274 Komagataella pastoris 44.15 3.00e-125 441.00
IUUC-Lch-049907 Latimeria chalumnae 81.13 0.00e+00 817.00
IUUC-Lpe-050778 Leersia perrieri 54.39 2.00e-153 535.00
IUUC-Loc-051889 Lepisosteus oculatus 79.70 0.00e+00 822.00
IUUC-Lma-053041 Leptosphaeria maculans 49.18 5.00e-116 411.00
IUUC-Laf-053598 Loxodonta africana 95.35 0.00e+00 940.00
IUUC-Mcc-055660 Macaca mulatta 95.14 0.00e+00 935.00
IUUC-Meu-056197 Macropus eugenii 78.68 0.00e+00 768.00
IUUC-Mor-056949 Magnaporthe oryzae 46.47 4.00e-120 425.00
IUUC-Mpo-057571 Magnaporthe poae 54.17 6.00e-64 238.00
IUUC-Mtr-058530 Medicago truncatula 57.87 4.00e-166 577.00
IUUC-Mla-059133 Melampsora laricipopulina 45.67 4.00e-124 438.00
IUUC-Mga-059252 Meleagris gallopavo 84.38 0.00e+00 662.00
IUUC-Mvi-060522 Microbotryum violaceum 49.80 3.00e-136 478.00
IUUC-Mmr-061117 Microcebus murinus 95.15 0.00e+00 932.00
IUUC-Mdo-062892 Monodelphis domestica 88.16 0.00e+00 883.00
IUUC-Mmu-064108 Mus musculus 95.77 0.00e+00 915.00
IUUC-Mac-064430 Musa acuminata 59.10 4.00e-173 600.00
IUUC-Mpu-065882 Mustela putorius furo 94.50 0.00e+00 927.00
IUUC-Mlu-068123 Myotis lucifugus 95.56 0.00e+00 939.00
IUUC-Nfi-068484 Neosartorya fischeri 47.18 7.00e-121 427.00
IUUC-Ncr-068649 Neurospora crassa 44.17 6.00e-116 410.00
IUUC-Nle-069140 Nomascus leucogenys 95.12 0.00e+00 929.00
IUUC-Opr-070220 Ochotona princeps 88.51 0.00e+00 818.00
IUUC-Ont-072643 Oreochromis niloticus 78.95 0.00e+00 813.00
IUUC-Ocu-074007 Oryctolagus cuniculus 95.99 0.00e+00 917.00
IUUC-Oba-075904 Oryza barthii 59.10 3.00e-173 601.00
IUUC-Obr-076280 Oryza brachyantha 58.67 2.00e-172 598.00
IUUC-Ogl-077425 Oryza glaberrima 59.10 2.00e-173 601.00
IUUC-Ogu-078586 Oryza glumaepatula 59.10 3.00e-173 601.00
IUUC-Oin-079489 Oryza indica 56.96 2.00e-164 572.00
IUUC-Olo-080766 Oryza longistaminata 58.97 4.00e-173 600.00
IUUC-Ome-081905 Oryza meridionalis 59.10 2.00e-173 602.00
IUUC-Oni-083022 Oryza nivara 59.10 1.00e-173 602.00
IUUC-Opu-083615 Oryza punctata 59.10 2.00e-173 601.00
IUUC-Oru-085076 Oryza rufipogon 59.10 1.00e-173 602.00
IUUC-Osa-085744 Oryza sativa 59.31 8.00e-174 603.00
IUUC-Ola-087290 Oryzias latipes 77.85 0.00e+00 801.00
IUUC-Olu-087898 Ostreococcus lucimarinus 53.04 1.00e-144 506.00
IUUC-Oga-088980 Otolemur garnettii 95.75 0.00e+00 934.00
IUUC-Oar-089580 Ovis aries 94.13 0.00e+00 809.00
IUUC-Ptr-090845 Pan troglodytes 94.69 0.00e+00 924.00
IUUC-Pan-092836 Papio anubis 95.35 0.00e+00 939.00
IUUC-Psi-093965 Pelodiscus sinensis 82.46 2.00e-56 210.00
IUUC-Pno-095052 Phaeosphaeria nodorum 46.79 4.00e-122 431.00
IUUC-Ppa-095432 Physcomitrella patens 58.42 2.00e-170 592.00
IUUC-Pfo-096963 Poecilia formosa 70.74 0.00e+00 697.00
IUUC-Pab-097716 Pongo abelii 91.30 0.00e+00 884.00
IUUC-Pop-099224 Populus trichocarpa 58.51 1.00e-171 595.00
IUUC-Pca-100682 Procavia capensis 91.27 0.00e+00 674.00
IUUC-Ppe-101819 Prunus persica 58.00 6.00e-169 587.00
IUUC-Pva-102338 Pteropus vampyrus 94.12 0.00e+00 707.00
IUUC-Pgr-103583 Puccinia graminis 54.77 5.00e-132 464.00
IUUC-Ptt-103737 Puccinia triticina 44.57 2.00e-99 356.00
IUUC-Pte-104150 Pyrenophora teres 49.10 3.00e-120 425.00
IUUC-Pyt-104606 Pyrenophora triticirepentis 49.43 5.00e-120 424.00
IUUC-Rno-105987 Rattus norvegicus 95.55 0.00e+00 937.00
IUUC-Sce-106315 Saccharomyces cerevisiae 47.56 2.00e-130 459.00
IUUC-Sha-107273 Sarcophilus harrisii 88.58 0.00e+00 892.00
IUUC-Sja-107677 Schizosaccharomyces japonicus 46.12 6.00e-118 417.00
IUUC-Spo-108092 Schizosaccharomyces pombe 48.05 5.00e-122 431.00
IUUC-Ssl-108442 Sclerotinia sclerotiorum 45.32 9.00e-118 417.00
IUUC-Smo-108855 Selaginella moellendorffii 56.26 2.00e-164 572.00
IUUC-Sit-110329 Setaria italica 59.10 1.00e-172 599.00
IUUC-Sly-111830 Solanum lycopersicum 59.31 2.00e-174 605.00
IUUC-Stu-112603 Solanum tuberosum 59.31 2.00e-174 605.00
IUUC-Sar-113504 Sorex araneus 90.07 2.00e-72 266.00
IUUC-Sbi-114560 Sorghum bicolor 58.46 1.00e-170 592.00
IUUC-Sre-115133 Sporisorium reilianum 40.95 9.00e-122 430.00
IUUC-Ssc-115903 Sus scrofa 94.50 0.00e+00 931.00
IUUC-Tgu-116798 Taeniopygia guttata 83.93 0.00e+00 850.00
IUUC-Tru-118361 Takifugu rubripes 77.05 0.00e+00 798.00
IUUC-Tsy-118849 Tarsius syrichta 95.74 0.00e+00 932.00
IUUC-Tni-120094 Tetraodon nigroviridis 77.26 0.00e+00 799.00
IUUC-Tca-121634 Theobroma cacao 57.87 4.00e-168 584.00
IUUC-Tre-122051 Trichoderma reesei 47.50 2.00e-121 429.00
IUUC-Tvi-122322 Trichoderma virens 47.19 4.00e-124 438.00
IUUC-Tae-125822 Triticum aestivum 58.67 5.00e-172 597.00
IUUC-Tur-126766 Triticum urartu 52.38 1.00e-163 569.00
IUUC-Tme-127175 Tuber melanosporum 50.63 6.00e-132 464.00
IUUC-Tbe-127779 Tupaia belangeri 94.85 0.00e+00 831.00
IUUC-Ttr-128224 Tursiops truncatus 90.19 0.00e+00 803.00
IUUC-Uma-129537 Ustilago maydis 41.65 9.00e-124 437.00
IUUC-Vda-129927 Verticillium dahliae 46.23 2.00e-112 399.00
IUUC-Vpa-130658 Vicugna pacos 82.55 0.00e+00 784.00
IUUC-Vvi-131659 Vitis vinifera 58.00 2.00e-170 592.00
IUUC-Xtr-132918 Xenopus tropicalis 75.79 0.00e+00 782.00
IUUC-Xma-133700 Xiphophorus maculatus 79.16 0.00e+00 810.00
IUUC-Yli-134478 Yarrowia lipolytica 49.59 3.00e-138 485.00
IUUC-Zma-135835 Zea mays 55.98 1.00e-167 582.00
Created Date 25-Jun-2017

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