iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ani-009443

Ensembl Protein ID

CADANIAP00009153

UniProt Accession

Q5BAI9; C8VP07; Q5BAI9_EMENI

Genbank Protein ID

CBF86860.1; EAA64147.1

Protein Name

NEDD8-activating enzyme E1 regulatory subunit

Genbank Nucleotide ID

BN001307; AACD01000040

Gene Name

ANIA_02441; AN2441.2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADANIAG00009153	CADANIAT00009153	CADANIAP00009153

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	3.20e-56	190.4	19	544

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagg............lGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaeal 81
           YDRQ+rlw + +q++l++++vllv+ +g            +G+E+lKnLvl Gvg +t+vD + v+  +l+ +F+++ e+ g+s+Ae +++ l
   Q: 19   YDRQLRLWAASGQQALEESRVLLVNSDGpwgnrstgvsgvVGVETLKNLVLPGVGGFTIVDPAVVTEPDLGVNFFLENESLGRSRAEETCRLL 111
           ************************98766666666666669**************************************************** PP
   S: 82   kelnpdvnveaheesiteleeeiv.FfkkfdvVvlaldnrear.rkvnrlclnarvpliesgtlGllGqvrviikgltecyscsd.....dpp 167
           kelnpdv++++ +++i e+ +e++  + +++++++    + ++ r + +   ++ +p + +++ G++++ +  ++ +  + + ++     +++
   Q: 112  KELNPDVEGSFRTKPIAEILQEEPgILAQHKLILISGPIEHSSlRALCDGAKKLAIPVLYTRSVGFYSTFSLQLPAVFPIVETHPdpestQDL 204
           **********************99*99999999775544444304445555566*********************99777776666999999* PP
   S: 168  qktiPfctlketpn..........aaehtiewavlfnklleeeageeevlekldseekeegkdkvkselks....edeenfeeaieiavkafa 246
           ++ +P+++l    +           ++ +++++ l+ ++le++++ ++++ +++++ek++++d v+s +++      een++ea+++++k+++
   Q: 205  RLLNPWPELTAAGAsirnldsfddHQHGHVPYVLLLLHYLEKWKETHNGSVPSNYKEKTAFRDFVRSCARTnnsqGGEENYDEAVAAVLKSLN 297
           **********99666667777777******************************************9999955555689************** PP
   S: 247  kttins.ikqllksfecdivtkskspfwv................................................................ 274
           +++  s +++++++ ec +++  +++fwv                                                                
   Q: 298  PFSLRSsTREIFEMEECRQLSAASADFWViasavrefyethqllplpgslpdmkaqsadyvslqniyktkarediaevtdiirrlesqlgraa 390
           ********************************************************************************************* PP
   S: 275  ........sfcsnaealq............vpekvekdeevvkasap....lylllralerfekkkgrkpgelsfekdddsavdlvtaaanlr 343
                    fc+na+ +q              e ++k+ +    +++     yl++++l+++ +  ++ +++++  +dd +  + + ++++ +
   Q: 391  rvddkdieIFCKNASHIQvirgrdipqvdgG-EDTKKRLRLELNNDEslipVYLAFEVLDTVVTGIQEGKYHQDALDDDGIWSSEIGRILAVI 482
           ******************6666555544431.3333333333233234779***********9999998889999999999888888888899 PP
   S: 344  aeslgiep..kldddlikeiagniipaiattnavvgGlaaqEviKvvsgkfeplknfflfda 403
           a + ++ +  +   d+ +e+ ++  ++++ +++  gGl+aqE++Kv++ +++pl+n+ +fd+
   Q: 483  AADAAVDEarNRVLDAAQELRRTKGGELHNISSLTGGLVAQEALKVLTRQYVPLDNTCIFDG 544
           999999985566678899******************************************97 PP

Organism

Aspergillus nidulans

Functional Description
(View)

Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.

Protein Sequence
(Fasta)

MTSEFPHALT GPSSKERKYD RQLRLWAASG QQALEESRVL LVNSDGPWGN RSTGVSGVVG 60
VETLKNLVLP GVGGFTIVDP AVVTEPDLGV NFFLENESLG RSRAEETCRL LKELNPDVEG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCATTCTGTC TTACATTACA CCCTGGGTTG AAATGACATC GGAGTTTCCC CACGCCTTAA 60
CAGGGCCCTC GTCTAAGGAG AGAAAATACG ATCGCCAGTT GCGGCTTTGG GCTGCCAGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR030667--APP-BP1
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd

Pfam

PF00899--ThiF

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

KEGG

ani:AN2441.2

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000764	Aegilops tauschii	32.24	4.00e-69	253.00
IUUC-Aml-002333	Ailuropoda melanoleuca	33.75	3.00e-85	307.00
IUUC-Atr-002644	Amborella trichopoda	30.41	7.00e-62	229.00
IUUC-Apl-003446	Anas platyrhynchos	33.09	2.00e-75	274.00
IUUC-Aca-004450	Anolis carolinensis	33.45	7.00e-83	299.00
IUUC-Aly-005466	Arabidopsis lyrata	31.19	1.00e-71	261.00
IUUC-Ath-006692	Arabidopsis thaliana	31.19	9.00e-73	265.00
IUUC-Ago-007900	Ashbya gossypii	25.37	6.00e-31	126.00
IUUC-Acl-008333	Aspergillus clavatus	72.58	0.00e+00	802.00
IUUC-Afl-008529	Aspergillus flavus	72.94	0.00e+00	809.00
IUUC-Afu-009071	Aspergillus fumigatus	73.61	0.00e+00	831.00
IUUC-Ang-009669	Aspergillus niger	73.53	0.00e+00	850.00
IUUC-Aor-009914	Aspergillus oryzae	72.29	0.00e+00	801.00
IUUC-Ate-010450	Aspergillus terreus	71.86	0.00e+00	803.00
IUUC-Ame-011183	Astyanax mexicanus	33.33	3.00e-86	310.00
IUUC-Bgr-012111	Blumeria graminis	43.72	2.00e-116	410.00
IUUC-Bta-012583	Bos taurus	33.51	3.00e-85	307.00
IUUC-Bci-013892	Botrytis cinerea	47.70	6.00e-133	465.00
IUUC-Bdi-014592	Brachypodium distachyon	32.42	1.00e-67	248.00
IUUC-Bol-016401	Brassica oleracea	32.29	4.00e-75	273.00
IUUC-Bra-017506	Brassica rapa	31.11	2.00e-70	258.00
IUUC-Cel-018456	Caenorhabditis elegans	32.27	1.00e-61	228.00
IUUC-Cja-020007	Callithrix jacchus	33.69	5.00e-85	306.00
IUUC-Cfa-020324	Canis familiaris	33.21	5.00e-85	306.00
IUUC-Cpo-022248	Cavia porcellus	29.26	9.00e-45	172.00
IUUC-Csa-023149	Chlorocebus sabaeus	30.54	6.00e-61	226.00
IUUC-Cho-024537	Choloepus hoffmanni	27.43	2.00e-46	178.00
IUUC-Cin-025763	Ciona intestinalis	35.05	3.00e-79	287.00
IUUC-Csv-026113	Ciona savignyi	34.12	4.00e-83	300.00
IUUC-Cgl-026428	Colletotrichum gloeosporioides	44.89	1.00e-125	441.00
IUUC-Cne-026884	Cryptococcus neoformans	29.75	5.00e-59	220.00
IUUC-Dre-028140	Danio rerio	33.63	2.00e-85	308.00
IUUC-Dno-030033	Dasypus novemcinctus	34.86	1.00e-76	278.00
IUUC-Dor-030513	Dipodomys ordii	47.46	2.00e-23	102.00
IUUC-Dse-031536	Dothistroma septosporum	45.79	5.00e-140	489.00
IUUC-Dme-031683	Drosophila melanogaster	34.18	1.00e-75	275.00
IUUC-Ete-032420	Echinops telfairi	30.00	7.00e-65	239.00
IUUC-Eca-033992	Equus caballus	30.70	2.00e-59	221.00
IUUC-Eeu-034713	Erinaceus europaeus	50.00	2.00e-25	108.00
IUUC-Fca-036548	Felis catus	32.97	7.00e-83	299.00
IUUC-Fal-037600	Ficedula albicollis	31.62	1.00e-72	265.00
IUUC-Fox-038037	Fusarium oxysporum	45.14	4.00e-129	453.00
IUUC-Fso-038387	Fusarium solani	43.71	8.00e-130	455.00
IUUC-Gmo-038562	Gadus morhua	32.38	4.00e-83	300.00
IUUC-Ggr-040005	Gaeumannomyces graminis	45.23	2.00e-133	467.00
IUUC-Gga-041129	Gallus gallus	34.36	2.00e-81	294.00
IUUC-Gac-042558	Gasterosteus aculeatus	34.06	9.00e-86	309.00
IUUC-Gma-043610	Glycine max	31.26	1.00e-69	255.00
IUUC-Ggo-045611	Gorilla gorilla	33.87	4.00e-85	306.00
IUUC-Hsa-046563	Homo sapiens	34.05	5.00e-87	313.00
IUUC-Hvu-047790	Hordeum vulgare	29.87	3.00e-39	154.00
IUUC-Itr-048066	Ictidomys tridecemlineatus	33.69	4.00e-85	306.00
IUUC-Kpa-049309	Komagataella pastoris	35.56	4.00e-76	276.00
IUUC-Lch-050038	Latimeria chalumnae	33.87	1.00e-79	288.00
IUUC-Lpe-051535	Leersia perrieri	29.45	2.00e-50	191.00
IUUC-Loc-051917	Lepisosteus oculatus	32.51	7.00e-77	279.00
IUUC-Lma-053112	Leptosphaeria maculans	48.78	4.00e-154	536.00
IUUC-Laf-053690	Loxodonta africana	34.05	1.00e-86	311.00
IUUC-Mcc-055117	Macaca mulatta	32.56	2.00e-80	291.00
IUUC-Meu-056761	Macropus eugenii	28.09	1.00e-58	219.00
IUUC-Mor-057230	Magnaporthe oryzae	44.43	1.00e-134	471.00
IUUC-Mpo-057514	Magnaporthe poae	46.41	4.00e-127	446.00
IUUC-Mtr-058551	Medicago truncatula	29.95	1.00e-62	232.00
IUUC-Mla-059183	Melampsora laricipopulina	33.04	1.00e-80	292.00
IUUC-Mga-060144	Meleagris gallopavo	33.33	3.00e-77	280.00
IUUC-Mvi-060221	Microbotryum violaceum	39.36	9.00e-70	256.00
IUUC-Mmr-061325	Microcebus murinus	32.44	8.00e-80	289.00
IUUC-Mdo-062532	Monodelphis domestica	33.94	4.00e-86	310.00
IUUC-Mmu-063956	Mus musculus	33.69	3.00e-86	310.00
IUUC-Mac-064521	Musa acuminata	32.07	8.00e-70	256.00
IUUC-Mpu-066716	Mustela putorius furo	34.78	5.00e-76	276.00
IUUC-Mlu-067459	Myotis lucifugus	33.45	9.00e-87	312.00
IUUC-Nfi-068245	Neosartorya fischeri	73.97	0.00e+00	827.00
IUUC-Ncr-068910	Neurospora crassa	46.84	6.00e-143	499.00
IUUC-Nle-070034	Nomascus leucogenys	31.92	5.00e-76	276.00
IUUC-Opr-070552	Ochotona princeps	32.29	2.00e-62	231.00
IUUC-Ont-071426	Oreochromis niloticus	34.12	8.00e-87	312.00
IUUC-Oan-073389	Ornithorhynchus anatinus	31.21	2.00e-56	211.00
IUUC-Ocu-074911	Oryctolagus cuniculus	33.33	3.00e-84	303.00
IUUC-Oba-075437	Oryza barthii	31.58	7.00e-58	216.00
IUUC-Obr-076684	Oryza brachyantha	31.16	5.00e-54	203.00
IUUC-Ogl-077170	Oryza glaberrima	31.58	7.00e-58	216.00
IUUC-Ogu-078844	Oryza glumaepatula	31.74	1.00e-51	195.00
IUUC-Oin-079105	Oryza indica	31.58	4.00e-58	217.00
IUUC-Olo-080943	Oryza longistaminata	29.94	2.00e-45	175.00
IUUC-Oni-082891	Oryza nivara	30.49	5.00e-52	197.00
IUUC-Opu-083457	Oryza punctata	31.76	9.00e-57	212.00
IUUC-Oru-084960	Oryza rufipogon	29.94	1.00e-45	175.00
IUUC-Osa-085358	Oryza sativa	31.34	4.00e-58	217.00
IUUC-Ola-086420	Oryzias latipes	32.98	3.00e-55	207.00
IUUC-Olu-087625	Ostreococcus lucimarinus	25.61	2.00e-39	154.00
IUUC-Oga-088810	Otolemur garnettii	33.39	5.00e-86	310.00
IUUC-Oar-089196	Ovis aries	33.33	1.00e-83	301.00
IUUC-Ptr-090617	Pan troglodytes	33.87	4.00e-86	310.00
IUUC-Pan-092761	Papio anubis	33.69	4.00e-86	310.00
IUUC-Psi-093191	Pelodiscus sinensis	32.47	2.00e-77	281.00
IUUC-Pma-094380	Petromyzon marinus	38.93	4.00e-77	280.00
IUUC-Pno-095084	Phaeosphaeria nodorum	46.33	2.00e-134	472.00
IUUC-Ppa-095875	Physcomitrella patens	30.43	2.00e-64	238.00
IUUC-Pfo-096467	Poecilia formosa	33.09	3.00e-84	303.00
IUUC-Pab-098255	Pongo abelii	35.00	7.00e-77	279.00
IUUC-Pop-099722	Populus trichocarpa	31.62	2.00e-68	251.00
IUUC-Pca-100807	Procavia capensis	35.42	2.00e-26	111.00
IUUC-Ppe-101280	Prunus persica	31.19	1.00e-72	265.00
IUUC-Pva-102333	Pteropus vampyrus	32.44	1.00e-76	278.00
IUUC-Pgr-103401	Puccinia graminis	30.61	8.00e-70	256.00
IUUC-Ptt-103889	Puccinia triticina	30.12	3.00e-65	241.00
IUUC-Pte-104355	Pyrenophora teres	49.48	5.00e-155	539.00
IUUC-Pyt-104545	Pyrenophora triticirepentis	50.87	4.00e-156	543.00
IUUC-Rno-105810	Rattus norvegicus	32.68	1.00e-83	301.00
IUUC-Sce-106397	Saccharomyces cerevisiae	25.24	7.00e-24	103.00
IUUC-Sha-106770	Sarcophilus harrisii	38.06	4.00e-51	192.00
IUUC-Sja-107926	Schizosaccharomyces japonicus	31.32	1.00e-72	265.00
IUUC-Spo-108276	Schizosaccharomyces pombe	32.66	4.00e-75	273.00
IUUC-Ssl-108387	Sclerotinia sclerotiorum	47.71	1.00e-135	474.00
IUUC-Smo-109296	Selaginella moellendorffii	33.27	4.00e-75	273.00
IUUC-Sit-110157	Setaria italica	31.81	8.00e-72	262.00
IUUC-Sly-111105	Solanum lycopersicum	31.74	2.00e-73	268.00
IUUC-Stu-112469	Solanum tuberosum	32.09	3.00e-73	267.00
IUUC-Sar-113083	Sorex araneus	24.45	1.00e-42	165.00
IUUC-Sbi-113813	Sorghum bicolor	31.27	8.00e-70	256.00
IUUC-Sre-115058	Sporisorium reilianum	36.52	8.00e-69	253.00
IUUC-Tgu-116772	Taeniopygia guttata	32.60	5.00e-74	270.00
IUUC-Tru-118686	Takifugu rubripes	34.23	6.00e-89	319.00
IUUC-Tsy-119111	Tarsius syrichta	34.24	5.00e-41	160.00
IUUC-Tni-120231	Tetraodon nigroviridis	30.22	6.00e-73	266.00
IUUC-Tca-121491	Theobroma cacao	31.08	1.00e-66	245.00
IUUC-Tre-122103	Trichoderma reesei	44.89	7.00e-132	462.00
IUUC-Tvi-122672	Trichoderma virens	43.26	9.00e-127	445.00
IUUC-Tae-125684	Triticum aestivum	32.24	1.00e-69	255.00
IUUC-Tur-126487	Triticum urartu	31.25	8.00e-65	239.00
IUUC-Tme-127097	Tuber melanosporum	39.50	2.00e-99	354.00
IUUC-Ttr-128465	Tursiops truncatus	30.71	1.00e-68	252.00
IUUC-Uma-129645	Ustilago maydis	36.75	1.00e-70	259.00
IUUC-Vda-129989	Verticillium dahliae	40.07	8.00e-100	355.00
IUUC-Vpa-130529	Vicugna pacos	31.37	3.00e-73	267.00
IUUC-Vvi-131059	Vitis vinifera	30.59	2.00e-69	254.00
IUUC-Xtr-132002	Xenopus tropicalis	35.21	3.00e-89	320.00
IUUC-Xma-133930	Xiphophorus maculatus	33.03	2.00e-81	295.00
IUUC-Yli-134505	Yarrowia lipolytica	34.62	1.00e-79	288.00
IUUC-Zma-135895	Zea mays	31.20	2.00e-68	251.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence