iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106636

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01134165

Gene Name

TBL1XR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000005700.1	ENSSHAT00000006608.1	ENSSHAP00000006551.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-53	176.8	349	387
UBD/Beta-Prp	6.40e-66	222.7	312	515

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHt++v+++++ ++ +ll+s+sdD t+k+W++++  +++
   Q: 349  GHTNEVNAIKWdPTgNLLASCSDDMTLKIWSMKQESCVH 387
           8***********778*****************9999986 PP

UBD/Beta-Prp

   S: 12   vitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlsl 100
           +  +v++ ++++ +a+ s+d +i v ++ +   +++++gh++ev+a+k++p+g++l+++s+D+t+k+w++++ +cvh l++h+++++++
   Q: 312  PALDVDW-QSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQESCVHDLQAHNKEIYTI 399
           4445555.677778888888888888888877788888888888888888888888888888888888888888888888888888888 PP
   S: 101  sfsp........sg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgght 180
           ++sp        +    l+s+s d+t+r+wd++ g c++ tl++h++ v +v+++pdg++l+sGs D++v +W+ +tg l++  +g  t
   Q: 400  KWSPtgpgtnnpNAnLMLASASFDSTVRLWDVDRGICIH-TLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG--T 485
           887766555444222467788888888888888888887.8888888888888888888888888888888888888888888877..7 PP
   S: 181  dsvyslsfdsngkelvsgsldgtvklwdlq 210
           + +  + ++  g  + + + dg+v + dl+
   Q: 486  GGIFEVCWNAAGDKVGASASDGSVCVLDLR 515
           788888888888888888888877777765 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

KMSISSDEVN FLVYRYLQES GFSHSAFTFG IESHISQSNI NGALVPPAAL ISIIQKGLQY 60
VEAEVSINED GTLFDGRPIE SLSLIDAVMP DVVQTRQQAY RDKLAQQQAA AAAAAATTTT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATCAACTCC ATGTGATTGG AAGTACCAAA TAAGTTGAGC TTCCCCACAT CAATGTACTG 60
CCAATGGTAA GAGAATTCTT TCTAGTTGGA ATCAGAGTAT GATGATTTAA CTTATACAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08513--LisH
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00667--LisH
SM00320--WD40

Gene Ontology

GO:0000118--C:histone deacetylase complex
GO:0005876--C:spindle microtubule
GO:0017053--C:transcriptional repressor complex
GO:0003714--F:transcription corepressor activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0060613--P:fat pad development
GO:0016042--P:lipid catabolic process
GO:0035264--P:multicellular organism growth
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0030814--P:regulation of cAMP metabolic process
GO:0090207--P:regulation of triglyceride metabolic process
GO:0002021--P:response to dietary excess
GO:0050872--P:white fat cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000916	Aegilops tauschii	60.00	2.00e-54	204.00
IUUC-Aml-001717	Ailuropoda melanoleuca	95.15	0.00e+00	951.00
IUUC-Atr-002514	Amborella trichopoda	65.11	1.00e-144	506.00
IUUC-Apl-003708	Anas platyrhynchos	98.18	0.00e+00	915.00
IUUC-Aca-004611	Anolis carolinensis	98.06	0.00e+00	952.00
IUUC-Aly-005622	Arabidopsis lyrata	58.40	9.00e-120	424.00
IUUC-Ath-007137	Arabidopsis thaliana	59.50	2.00e-121	429.00
IUUC-Ame-011601	Astyanax mexicanus	92.43	0.00e+00	903.00
IUUC-Bta-012418	Bos taurus	98.06	0.00e+00	976.00
IUUC-Bdi-014315	Brachypodium distachyon	60.42	2.00e-134	472.00
IUUC-Bol-016277	Brassica oleracea	57.25	5.00e-127	447.00
IUUC-Bra-016944	Brassica rapa	60.28	3.00e-126	445.00
IUUC-Cja-018832	Callithrix jacchus	98.26	0.00e+00	956.00
IUUC-Cfa-020029	Canis familiaris	94.95	0.00e+00	950.00
IUUC-Cpo-022080	Cavia porcellus	92.84	0.00e+00	914.00
IUUC-Csa-024075	Chlorocebus sabaeus	95.34	0.00e+00	950.00
IUUC-Cho-024872	Choloepus hoffmanni	96.60	1.00e-110	393.00
IUUC-Dre-028075	Danio rerio	95.34	0.00e+00	923.00
IUUC-Dno-029196	Dasypus novemcinctus	98.45	0.00e+00	957.00
IUUC-Dor-030732	Dipodomys ordii	98.90	0.00e+00	730.00
IUUC-Eeu-034952	Erinaceus europaeus	88.06	0.00e+00	821.00
IUUC-Fca-035734	Felis catus	98.06	0.00e+00	955.00
IUUC-Fal-037185	Ficedula albicollis	98.25	0.00e+00	956.00
IUUC-Gmo-038870	Gadus morhua	90.10	0.00e+00	926.00
IUUC-Gga-041161	Gallus gallus	98.45	0.00e+00	956.00
IUUC-Gac-041844	Gasterosteus aculeatus	95.34	0.00e+00	959.00
IUUC-Ggo-044882	Gorilla gorilla	95.34	0.00e+00	950.00
IUUC-Hsa-046488	Homo sapiens	95.34	0.00e+00	950.00
IUUC-Itr-047958	Ictidomys tridecemlineatus	99.45	0.00e+00	738.00
IUUC-Lch-050672	Latimeria chalumnae	96.89	0.00e+00	974.00
IUUC-Lpe-051084	Leersia perrieri	62.91	8.00e-137	480.00
IUUC-Loc-052030	Lepisosteus oculatus	95.75	0.00e+00	962.00
IUUC-Laf-054280	Loxodonta africana	97.67	0.00e+00	975.00
IUUC-Mcc-055203	Macaca mulatta	95.35	0.00e+00	952.00
IUUC-Meu-056563	Macropus eugenii	99.16	7.00e-136	476.00
IUUC-Mga-059660	Meleagris gallopavo	98.45	0.00e+00	956.00
IUUC-Mvi-060557	Microbotryum violaceum	36.77	6.00e-71	262.00
IUUC-Mmr-060925	Microcebus murinus	97.01	0.00e+00	914.00
IUUC-Mdo-062078	Monodelphis domestica	99.42	0.00e+00	963.00
IUUC-Mmu-063603	Mus musculus	97.86	0.00e+00	950.00
IUUC-Mac-065508	Musa acuminata	45.73	3.00e-104	371.00
IUUC-Mpu-066741	Mustela putorius furo	94.95	0.00e+00	950.00
IUUC-Mlu-068152	Myotis lucifugus	98.25	0.00e+00	948.00
IUUC-Nle-069229	Nomascus leucogenys	95.34	0.00e+00	950.00
IUUC-Opr-070277	Ochotona princeps	87.60	0.00e+00	806.00
IUUC-Ont-072623	Oreochromis niloticus	95.73	0.00e+00	960.00
IUUC-Ocu-074280	Oryctolagus cuniculus	96.57	0.00e+00	947.00
IUUC-Obr-076718	Oryza brachyantha	59.95	1.00e-136	479.00
IUUC-Olo-080427	Oryza longistaminata	63.04	1.00e-131	463.00
IUUC-Ola-087365	Oryzias latipes	94.96	0.00e+00	958.00
IUUC-Oga-088357	Otolemur garnettii	94.17	0.00e+00	900.00
IUUC-Oar-089214	Ovis aries	98.26	0.00e+00	981.00
IUUC-Ptr-091532	Pan troglodytes	95.34	0.00e+00	950.00
IUUC-Pan-091927	Papio anubis	95.34	0.00e+00	950.00
IUUC-Psi-093941	Pelodiscus sinensis	92.80	0.00e+00	937.00
IUUC-Pma-094105	Petromyzon marinus	65.99	4.00e-101	360.00
IUUC-Ppa-095868	Physcomitrella patens	64.89	4.00e-139	488.00
IUUC-Pfo-096158	Poecilia formosa	95.15	0.00e+00	959.00
IUUC-Pab-098705	Pongo abelii	95.34	0.00e+00	950.00
IUUC-Pca-100256	Procavia capensis	97.65	0.00e+00	941.00
IUUC-Pva-102616	Pteropus vampyrus	97.83	0.00e+00	934.00
IUUC-Rno-105411	Rattus norvegicus	98.06	0.00e+00	953.00
IUUC-Smo-109301	Selaginella moellendorffii	63.76	4.00e-143	501.00
IUUC-Sit-110710	Setaria italica	63.43	6.00e-142	497.00
IUUC-Sar-112971	Sorex araneus	86.69	0.00e+00	862.00
IUUC-Sbi-114420	Sorghum bicolor	62.91	8.00e-142	497.00
IUUC-Sre-115175	Sporisorium reilianum	38.00	4.00e-58	219.00
IUUC-Ssc-115695	Sus scrofa	96.50	0.00e+00	933.00
IUUC-Tgu-117009	Taeniopygia guttata	98.43	0.00e+00	942.00
IUUC-Tru-118581	Takifugu rubripes	94.95	0.00e+00	960.00
IUUC-Tsy-119424	Tarsius syrichta	81.10	0.00e+00	722.00
IUUC-Tni-119986	Tetraodon nigroviridis	95.15	0.00e+00	961.00
IUUC-Tca-121739	Theobroma cacao	53.83	2.00e-124	439.00
IUUC-Tae-125368	Triticum aestivum	61.35	3.00e-135	475.00
IUUC-Tur-126856	Triticum urartu	60.61	6.00e-62	231.00
IUUC-Tme-127126	Tuber melanosporum	38.24	1.00e-58	220.00
IUUC-Tbe-127665	Tupaia belangeri	82.88	0.00e+00	826.00
IUUC-Uma-129469	Ustilago maydis	42.75	2.00e-58	221.00
IUUC-Vpa-130768	Vicugna pacos	94.90	0.00e+00	935.00
IUUC-Xtr-132842	Xenopus tropicalis	92.57	0.00e+00	905.00
IUUC-Xma-134020	Xiphophorus maculatus	95.16	0.00e+00	961.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence