iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054450

UUCD1 version

UUC-LoA-00667

Ensembl Protein ID

ENSLAFP00000016752.2

UniProt Accession

G3TNE3; G3TNE3_LOXAF

Protein Name

Uncharacterized protein

Gene Name

WDR27

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000022577.2	ENSLAFT00000021735.2	ENSLAFP00000016752.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.40e-29	99.4	100	139
UBD/Beta-Prp	8.10e-46	156.9	453	749

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH ++vt+laf     +l++s+s D t+kvWD + g++++
   Q: 100  GHLAPVTSLAFcaWQaNLVISASEDRTVKVWDCHVGTSVH 139
           89*******99983449***************99888776 PP

UBD/Beta-Prp

   S: 11   svitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls................. 82
           + ++c+++s d++ la g +++ + v+d++   + + +sgh+++v++v++s++g++lv++s Dr +++w+ +                 
   Q: 453  TMVCCLQYSGDGQRLACGLANHLLLVFDASLTGTPAAFSGHDGPVSTVSWSHSGEWLVSASPDRSLRLWSAQgavhtvllgkdvfpkpi 541
           57899****************************************************************99999999999999****** PP
   S: 83   .........................................tgkcvhtlk.ghedsvlslsfsp..sgdklvsGshdrtirvwdletgq 127
                                                    ++++vh l+ ++ ++++sls     +++ ++++++ rt++++dl+  +
   Q: 542  qfaqfyyidafillssgpefhllkyhvdtrrdeikrykqksKCQPVHRLSmANAAEITSLSAANdfYSYIVLTAGRNRTLEIFDLNA-S 629
           ***************************************88888899998889999****99997777888999*********9865.5 PP
   S: 128  clee...........tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvysls..fdsngkelvsgsldg 202
           c+ +              +++g+   v+ + ++ nl+ +++    ++lWd++t+++ r+++g h ++ +     ++  g++++ g++d+
   Q: 630  CSAAvipeahsrpvhQICQNKGSPFAVQQP-EAyNLFLTAAVGDGIKLWDMRTQRCERRFEG-HANRCHPCGvaLSACGRHVACGAEDR 716
           555567777777754223344444455544.555**************************99.9999986554488999********** PP
   S: 203  tvklwdlqtgecvrtlnghtdnvksvrfspnde 235
           +v l+++ +++  r+l ghtd+v++v+fsp   
   Q: 717  YVYLYEMGSSTFSRRLGGHTDTVTRVAFSPSAP 749
           ****************************97665 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

QFLILRGHHQ SITAVAFGNK VSPLLVCSAS RDYVIVWNLE ECKENALQGA APRGTVLGTL 60
MGKVLCLRFS PDDHAVGVCT GNKIVMLDAE GPSVLAELQG HLAPVTSLAF CAWQANLVIS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGTTTCTAA TCCTAAGAGG ACACCATCAG TCCATAACTG CCGTGGCTTT TGGAAATAAA 60
GTGAGTCCGC TTCTTGTCTG CTCTGCGTCA CGTGACTACG TCATAGTGTG GAACTTGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002258	Ailuropoda melanoleuca	61.78	0.00e+00	752.00
IUUC-Aca-004807	Anolis carolinensis	55.58	0.00e+00	877.00
IUUC-Bta-013316	Bos taurus	61.95	0.00e+00	914.00
IUUC-Cja-018825	Callithrix jacchus	60.43	0.00e+00	971.00
IUUC-Cfa-020895	Canis familiaris	63.29	0.00e+00	979.00
IUUC-Cpo-022282	Cavia porcellus	60.34	0.00e+00	927.00
IUUC-Csa-023439	Chlorocebus sabaeus	64.39	0.00e+00	924.00
IUUC-Cho-025046	Choloepus hoffmanni	61.74	0.00e+00	709.00
IUUC-Dre-028376	Danio rerio	41.37	6.00e-149	521.00
IUUC-Dno-029649	Dasypus novemcinctus	73.89	0.00e+00	905.00
IUUC-Dor-030824	Dipodomys ordii	53.93	0.00e+00	687.00
IUUC-Eca-033270	Equus caballus	66.31	0.00e+00	1021.00
IUUC-Fca-036149	Felis catus	60.53	0.00e+00	925.00
IUUC-Fal-037410	Ficedula albicollis	52.83	0.00e+00	719.00
IUUC-Gmo-038923	Gadus morhua	37.27	4.00e-124	438.00
IUUC-Gga-040974	Gallus gallus	52.31	0.00e+00	789.00
IUUC-Gac-042310	Gasterosteus aculeatus	40.00	8.00e-105	374.00
IUUC-Ggo-044557	Gorilla gorilla	63.90	0.00e+00	1001.00
IUUC-Hsa-046312	Homo sapiens	65.01	0.00e+00	1007.00
IUUC-Itr-049033	Ictidomys tridecemlineatus	60.05	0.00e+00	899.00
IUUC-Mcc-055807	Macaca mulatta	60.37	0.00e+00	777.00
IUUC-Meu-056116	Macropus eugenii	47.56	2.00e-61	230.00
IUUC-Mga-060088	Meleagris gallopavo	51.87	0.00e+00	684.00
IUUC-Mdo-062857	Monodelphis domestica	61.91	0.00e+00	989.00
IUUC-Mmu-063220	Mus musculus	60.15	0.00e+00	786.00
IUUC-Mpu-066921	Mustela putorius furo	59.89	0.00e+00	850.00
IUUC-Mlu-067717	Myotis lucifugus	58.74	0.00e+00	763.00
IUUC-Nle-069061	Nomascus leucogenys	53.38	0.00e+00	761.00
IUUC-Opr-070612	Ochotona princeps	56.59	6.00e-78	285.00
IUUC-Ont-072187	Oreochromis niloticus	41.98	2.00e-162	566.00
IUUC-Oan-072701	Ornithorhynchus anatinus	53.44	6.00e-139	487.00
IUUC-Ocu-074602	Oryctolagus cuniculus	62.82	0.00e+00	972.00
IUUC-Ola-086633	Oryzias latipes	39.07	8.00e-126	444.00
IUUC-Oga-088499	Otolemur garnettii	67.33	0.00e+00	1025.00
IUUC-Oar-089256	Ovis aries	61.72	0.00e+00	901.00
IUUC-Ptr-091545	Pan troglodytes	61.11	5.00e-172	597.00
IUUC-Pan-092299	Papio anubis	62.59	0.00e+00	983.00
IUUC-Psi-093010	Pelodiscus sinensis	57.93	0.00e+00	904.00
IUUC-Pab-097646	Pongo abelii	57.01	3.00e-160	558.00
IUUC-Pca-100720	Procavia capensis	70.62	3.00e-160	558.00
IUUC-Pva-102808	Pteropus vampyrus	53.72	0.00e+00	758.00
IUUC-Rno-105715	Rattus norvegicus	60.29	0.00e+00	908.00
IUUC-Sha-107546	Sarcophilus harrisii	60.21	0.00e+00	964.00
IUUC-Sar-113543	Sorex araneus	53.45	0.00e+00	726.00
IUUC-Ssc-116335	Sus scrofa	69.75	8.00e-46	176.00
IUUC-Tgu-117249	Taeniopygia guttata	52.37	0.00e+00	719.00
IUUC-Tsy-119238	Tarsius syrichta	59.42	0.00e+00	763.00
IUUC-Tni-120639	Tetraodon nigroviridis	34.13	2.00e-44	172.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence