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Tag Content
UUCD2 ID IUUC-Cin-025572
UUCD1 version UUC-CiI-00258
Ensembl Protein ID ENSCINP00000018763.3
UniProt Accession F6W1H2; F6W1H2_CIOIN
Genbank Protein ID ENSCINP00000018763
Protein Name Coatomer subunit alpha
Genbank Nucleotide ID EAAA01002234
Gene Name LOC100185196
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCING00000009231.3 ENSCINT00000018763.3 ENSCINP00000018763.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 8.40e-33 110.8 50 80
UBD/Beta-Prp 5.50e-74 248.8 3 333
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           H ++v++++f s  +l+vsG+dD +ik+W++
   Q: 50   HDGPVRGVCFhSQqPLFVSGGDDYKIKIWNY 80
           99********9667***************96 PP
   

   UBD/Beta-Prp
   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkg 92
           t +++++++++ + f+p++++++++  +g+i++wd+++ +l+ ++++h+++v+ v+f+++++++v+g++D+ ik+w+++ + c+ tl g
   Q: 3    TKFETKSARVKGLSFHPKRPWVLSSLHNGCIQLWDYRMCTLIDKFEEHDGPVRGVCFHSQQPLFVSGGDDYKIKIWNYKLRRCLFTLLG 91
           67889999********************************************************************************* PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl............... 166
           h d++++  f+ +  +++s+s+d+tir+w+++++ c+  +l+gh++ v+++++hp+++l+vs+slD+t r+Wd+               
   Q: 92   HLDYIRTAVFHHEYPWILSASDDQTIRIWNWQSRNCIA-VLTGHNHYVMSAQFHPTDDLIVSASLDQTARVWDIsglrkknlspggnsl 179
           **************************************.************************************************** PP
   S: 167  .....................ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfsp 232
                                +t++l+++  +gh++ v++  f+++ + +v++++d+ vklw + +++   v++++gh +nv++  f+p
   Q: 180  eetvrgtpgsaggpssielfgSTDFLVKHVLEGHDRGVNWACFHPSLPVVVTAADDRLVKLWRMNESKAweVDSCRGHYNNVSCCSFHP 268
           *****************************9888********************************888878****************** PP
   S: 233  nderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkknep 299
           ++++++s+s+D+sir+Wd+ ++  ++++ + +++++  ++ +++ n +++g  d+   i+kl++++p
   Q: 269  RQDLIISASEDKSIRVWDMGKRSSIQSFRRDQDRFWILSC-HPTLNLFAAGH-DNGMVIFKLERERP 333
           ****************************************.88877777764.67899999988765 PP
   
Organism Ciona intestinalis
Functional Description
(View)

Functional Description


     The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.
 The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.
Protein Sequence
(Fasta)
MLTKFETKSA RVKGLSFHPK RPWVLSSLHN GCIQLWDYRM CTLIDKFEEH DGPVRGVCFH 60
SQQPLFVSGG DDYKIKIWNY KLRRCLFTLL GHLDYIRTAV FHHEYPWILS ASDDQTIRIW 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cin-025572|E3,WD_repeat;UBD,Beta-Prp|Ciona intestinalis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTTAATTTGG TCTCTTTTAT TTAAATTGAA GCTTAAATAA GATTTATTTG TTGCAGCATC 60
ATCAGTTTGG TAACTGCTAT AAGTAGTGGG TATATAAAAC AGAAAGGCGA GAAATTAACG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cin-025572|E3,WD_repeat;UBD,Beta-Prp|Ciona intestinalis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER
KEGG cin:100185196
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000064 Aegilops tauschii 57.86 0.00e+00 1017.00
IUUC-Aml-001758 Ailuropoda melanoleuca 72.49 0.00e+00 1878.00
IUUC-Atr-002493 Amborella trichopoda 59.66 0.00e+00 1034.00
IUUC-Apl-003385 Anas platyrhynchos 71.08 0.00e+00 1565.00
IUUC-Aca-005154 Anolis carolinensis 79.17 7.00e-104 367.00
IUUC-Aly-006020 Arabidopsis lyrata 57.19 0.00e+00 1001.00
IUUC-Ath-007058 Arabidopsis thaliana 57.19 0.00e+00 1001.00
IUUC-Ago-007992 Ashbya gossypii 42.55 0.00e+00 963.00
IUUC-Acl-008027 Aspergillus clavatus 54.89 0.00e+00 971.00
IUUC-Afl-008644 Aspergillus flavus 55.68 0.00e+00 967.00
IUUC-Afu-008964 Aspergillus fumigatus 55.56 0.00e+00 974.00
IUUC-Ani-009379 Aspergillus nidulans 55.44 0.00e+00 969.00
IUUC-Ang-009756 Aspergillus niger 55.85 0.00e+00 982.00
IUUC-Aor-010174 Aspergillus oryzae 55.68 0.00e+00 967.00
IUUC-Ate-010302 Aspergillus terreus 48.27 0.00e+00 1183.00
IUUC-Ame-011229 Astyanax mexicanus 71.66 0.00e+00 1815.00
IUUC-Bgr-012300 Blumeria graminis 46.93 0.00e+00 1090.00
IUUC-Bta-012524 Bos taurus 72.85 0.00e+00 1868.00
IUUC-Bci-013781 Botrytis cinerea 55.13 0.00e+00 978.00
IUUC-Bdi-014549 Brachypodium distachyon 50.24 0.00e+00 1245.00
IUUC-Bol-015925 Brassica oleracea 57.31 0.00e+00 1000.00
IUUC-Bra-016978 Brassica rapa 56.83 0.00e+00 996.00
IUUC-Cel-018115 Caenorhabditis elegans 60.17 0.00e+00 1050.00
IUUC-Cja-019107 Callithrix jacchus 71.58 0.00e+00 1849.00
IUUC-Cfa-020675 Canis familiaris 72.20 0.00e+00 1848.00
IUUC-Cpo-021813 Cavia porcellus 72.93 0.00e+00 1884.00
IUUC-Cre-022969 Chlamydomonas reinhardtii 60.24 0.00e+00 1042.00
IUUC-Csa-023523 Chlorocebus sabaeus 73.58 0.00e+00 1889.00
IUUC-Cho-024704 Choloepus hoffmanni 62.13 0.00e+00 1438.00
IUUC-Csv-025864 Ciona savignyi 89.23 0.00e+00 2095.00
IUUC-Cgl-026510 Colletotrichum gloeosporioides 55.68 0.00e+00 986.00
IUUC-Cne-027053 Cryptococcus neoformans 56.23 0.00e+00 1005.00
IUUC-Cme-027222 Cyanidioschyzon merolae 39.94 5.00e-141 494.00
IUUC-Dre-027421 Danio rerio 71.56 0.00e+00 1804.00
IUUC-Dno-029303 Dasypus novemcinctus 72.78 0.00e+00 1877.00
IUUC-Dor-030290 Dipodomys ordii 65.19 0.00e+00 723.00
IUUC-Dse-031543 Dothistroma septosporum 45.40 0.00e+00 1092.00
IUUC-Dme-031945 Drosophila melanogaster 70.55 0.00e+00 1187.00
IUUC-Ete-032873 Echinops telfairi 73.30 0.00e+00 1301.00
IUUC-Eca-033773 Equus caballus 70.69 0.00e+00 1811.00
IUUC-Eeu-034874 Erinaceus europaeus 62.97 0.00e+00 1079.00
IUUC-Fca-035739 Felis catus 72.24 0.00e+00 1839.00
IUUC-Fal-037263 Ficedula albicollis 68.84 0.00e+00 1692.00
IUUC-Fox-037738 Fusarium oxysporum 48.23 0.00e+00 1170.00
IUUC-Fso-038153 Fusarium solani 54.38 0.00e+00 987.00
IUUC-Gmo-039602 Gadus morhua 67.39 0.00e+00 1684.00
IUUC-Ggr-039931 Gaeumannomyces graminis 54.67 0.00e+00 980.00
IUUC-Gga-040590 Gallus gallus 73.74 0.00e+00 1898.00
IUUC-Gac-041318 Gasterosteus aculeatus 71.05 0.00e+00 1837.00
IUUC-Gma-043354 Glycine max 58.65 0.00e+00 1018.00
IUUC-Ggo-045029 Gorilla gorilla 73.13 0.00e+00 1882.00
IUUC-Hsa-046078 Homo sapiens 73.05 0.00e+00 1880.00
IUUC-Hvu-047556 Hordeum vulgare 50.00 0.00e+00 1244.00
IUUC-Itr-048881 Ictidomys tridecemlineatus 70.11 0.00e+00 1246.00
IUUC-Kpa-049256 Komagataella pastoris 50.54 0.00e+00 889.00
IUUC-Lch-049706 Latimeria chalumnae 72.29 0.00e+00 1846.00
IUUC-Lpe-051316 Leersia perrieri 58.22 0.00e+00 1022.00
IUUC-Loc-051867 Lepisosteus oculatus 60.47 0.00e+00 998.00
IUUC-Lma-053138 Leptosphaeria maculans 54.40 0.00e+00 978.00
IUUC-Laf-053510 Loxodonta africana 73.38 0.00e+00 1889.00
IUUC-Mcc-055836 Macaca mulatta 72.52 0.00e+00 1887.00
IUUC-Meu-056238 Macropus eugenii 69.42 0.00e+00 981.00
IUUC-Mor-057172 Magnaporthe oryzae 54.48 0.00e+00 969.00
IUUC-Mpo-057300 Magnaporthe poae 54.90 0.00e+00 980.00
IUUC-Mtr-058248 Medicago truncatula 59.62 0.00e+00 1033.00
IUUC-Mla-059019 Melampsora laricipopulina 56.62 0.00e+00 1008.00
IUUC-Mga-059499 Meleagris gallopavo 73.54 0.00e+00 1890.00
IUUC-Mvi-060336 Microbotryum violaceum 50.16 0.00e+00 1200.00
IUUC-Mmr-061102 Microcebus murinus 72.22 0.00e+00 1872.00
IUUC-Mdo-062594 Monodelphis domestica 73.42 0.00e+00 1883.00
IUUC-Mmu-063736 Mus musculus 72.81 0.00e+00 1872.00
IUUC-Mac-065272 Musa acuminata 47.58 0.00e+00 1139.00
IUUC-Mpu-066701 Mustela putorius furo 72.46 0.00e+00 1874.00
IUUC-Mlu-067392 Myotis lucifugus 73.20 0.00e+00 1880.00
IUUC-Nfi-068270 Neosartorya fischeri 55.74 0.00e+00 975.00
IUUC-Ncr-068892 Neurospora crassa 56.03 0.00e+00 985.00
IUUC-Nle-069634 Nomascus leucogenys 79.07 0.00e+00 1159.00
IUUC-Opr-070952 Ochotona princeps 61.47 0.00e+00 1287.00
IUUC-Ont-072488 Oreochromis niloticus 72.32 0.00e+00 1843.00
IUUC-Ocu-074211 Oryctolagus cuniculus 72.93 0.00e+00 1885.00
IUUC-Oba-075761 Oryza barthii 58.22 0.00e+00 1023.00
IUUC-Obr-076429 Oryza brachyantha 57.62 0.00e+00 1012.00
IUUC-Ogl-077364 Oryza glaberrima 58.22 0.00e+00 1023.00
IUUC-Ogu-078257 Oryza glumaepatula 58.34 0.00e+00 1023.00
IUUC-Oin-080029 Oryza indica 58.22 0.00e+00 1021.00
IUUC-Olo-080466 Oryza longistaminata 58.24 0.00e+00 1019.00
IUUC-Ome-081993 Oryza meridionalis 59.68 0.00e+00 965.00
IUUC-Oni-082874 Oryza nivara 58.22 0.00e+00 1023.00
IUUC-Opu-083885 Oryza punctata 58.34 0.00e+00 1022.00
IUUC-Oru-084274 Oryza rufipogon 58.22 0.00e+00 1024.00
IUUC-Osa-085565 Oryza sativa 58.22 0.00e+00 1024.00
IUUC-Ola-086921 Oryzias latipes 70.37 0.00e+00 1808.00
IUUC-Olu-087639 Ostreococcus lucimarinus 61.32 0.00e+00 1064.00
IUUC-Oga-087991 Otolemur garnettii 68.98 0.00e+00 1761.00
IUUC-Oar-089590 Ovis aries 72.85 0.00e+00 1885.00
IUUC-Ptr-090808 Pan troglodytes 73.05 0.00e+00 1881.00
IUUC-Pan-092475 Papio anubis 73.20 0.00e+00 1875.00
IUUC-Psi-093044 Pelodiscus sinensis 66.75 0.00e+00 1112.00
IUUC-Pno-094839 Phaeosphaeria nodorum 45.98 0.00e+00 1051.00
IUUC-Ppa-095254 Physcomitrella patens 53.63 0.00e+00 1314.00
IUUC-Pfo-097493 Poecilia formosa 72.08 0.00e+00 1822.00
IUUC-Pab-098497 Pongo abelii 73.50 0.00e+00 1888.00
IUUC-Pop-099992 Populus trichocarpa 59.30 0.00e+00 1023.00
IUUC-Pca-100413 Procavia capensis 70.18 0.00e+00 842.00
IUUC-Ppe-101392 Prunus persica 51.08 0.00e+00 1236.00
IUUC-Pva-102126 Pteropus vampyrus 69.83 0.00e+00 1789.00
IUUC-Pgr-103376 Puccinia graminis 50.36 0.00e+00 1238.00
IUUC-Ptt-103978 Puccinia triticina 49.62 0.00e+00 776.00
IUUC-Pte-104126 Pyrenophora teres 55.76 0.00e+00 942.00
IUUC-Pyt-104778 Pyrenophora triticirepentis 46.35 1.00e-172 599.00
IUUC-Rno-105428 Rattus norvegicus 73.10 0.00e+00 1882.00
IUUC-Sce-106464 Saccharomyces cerevisiae 42.48 0.00e+00 954.00
IUUC-Sha-107301 Sarcophilus harrisii 72.89 0.00e+00 1858.00
IUUC-Sja-107961 Schizosaccharomyces japonicus 52.40 0.00e+00 911.00
IUUC-Spo-108217 Schizosaccharomyces pombe 45.24 0.00e+00 1086.00
IUUC-Ssl-108643 Sclerotinia sclerotiorum 55.13 0.00e+00 978.00
IUUC-Smo-109582 Selaginella moellendorffii 60.48 0.00e+00 1071.00
IUUC-Sit-109697 Setaria italica 58.10 0.00e+00 1021.00
IUUC-Sly-111759 Solanum lycopersicum 51.08 0.00e+00 1252.00
IUUC-Stu-112564 Solanum tuberosum 50.84 0.00e+00 1249.00
IUUC-Sar-113313 Sorex araneus 64.24 0.00e+00 1056.00
IUUC-Sbi-114388 Sorghum bicolor 58.46 0.00e+00 1023.00
IUUC-Sre-115209 Sporisorium reilianum 56.28 0.00e+00 1005.00
IUUC-Ssc-115933 Sus scrofa 73.01 0.00e+00 1887.00
IUUC-Tgu-117109 Taeniopygia guttata 61.13 1.00e-160 558.00
IUUC-Tru-117772 Takifugu rubripes 70.97 0.00e+00 1791.00
IUUC-Tsy-119105 Tarsius syrichta 64.53 0.00e+00 1633.00
IUUC-Tni-120556 Tetraodon nigroviridis 57.45 0.00e+00 1226.00
IUUC-Tca-121046 Theobroma cacao 58.51 0.00e+00 1025.00
IUUC-Tre-121951 Trichoderma reesei 58.49 0.00e+00 980.00
IUUC-Tvi-122359 Trichoderma virens 56.39 0.00e+00 991.00
IUUC-Tae-123611 Triticum aestivum 57.86 0.00e+00 1017.00
IUUC-Tur-126754 Triticum urartu 57.86 0.00e+00 1016.00
IUUC-Tme-127170 Tuber melanosporum 47.39 0.00e+00 1163.00
IUUC-Tbe-127882 Tupaia belangeri 56.27 0.00e+00 645.00
IUUC-Ttr-128217 Tursiops truncatus 70.64 0.00e+00 1813.00
IUUC-Uma-129337 Ustilago maydis 56.28 0.00e+00 1003.00
IUUC-Vda-129828 Verticillium dahliae 47.54 0.00e+00 1129.00
IUUC-Vpa-130537 Vicugna pacos 72.08 0.00e+00 1847.00
IUUC-Vvi-130958 Vitis vinifera 58.70 0.00e+00 1027.00
IUUC-Xtr-132857 Xenopus tropicalis 70.20 0.00e+00 1739.00
IUUC-Xma-133138 Xiphophorus maculatus 71.83 0.00e+00 1818.00
IUUC-Yli-134399 Yarrowia lipolytica 49.42 0.00e+00 833.00
IUUC-Zma-135612 Zea mays 50.20 0.00e+00 1234.00
Created Date 25-Jun-2017

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