iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000021646.1	ENSSTOT00000029188.1	ENSSTOP00000015342.1
ENSSTOG00000021646.1	ENSSTOT00000022031.1	ENSSTOP00000017536.1
ENSSTOG00000021646.1	ENSSTOT00000028804.1	ENSSTOP00000020778.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.80e-59	192.7	41	80
UBD/Beta-Prp	1.00e-133	445.1	661	879

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdD..gtikvWDlrtgvllk 37
           Ht +v claf sd  +l+s + D  +t+ +WD+r+g+ll 
   Q: 41   HTHGVACLAFdSDgQRLASVGLDakNTVCIWDWRKGKLLA 80
           99*********999*******9999***********9875 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatg..srdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtl 90
           gh+++ ++ ++++p k+++atg  +rd+ i vwd++t k+l+ l  +h+ +v a++fs dgk lv+++ D  + i  wd ++g+ + t 
   Q: 661  GHDDDILS-LTIHPVKDYVATGqvGRDAAIHVWDTQTLKCLSLLkGQHQRGVCALDFSADGKCLVSVGLDdfHSIVFWDWKKGEKIATT 748
           45555555.999*********95569******************7789**********************77788889*********** PP
   S: 91   kghedsvlslsfspsg.dklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           +gh+d++  ++ +p   dklv+ +  + i+ w+   g   ++      +g+ ++ +cv++   ++l++sG++ + + +W  k   ll+t
   Q: 749  RGHKDKIFVVKCNPHHvDKLVTVG-MKHIKFWQQAGGGFTSKrgifGSAGKLETMMCVSYGRMEDLVFSGAATGDIFIW--KDVLLLKT 834
           **************7769999988.99*****98888888889998899******************************..8899**** PP
   S: 175  ltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght 222
            +  h+++v  +   +  k +v+g++dg v+lwd   ++c++t+   +
   Q: 835  VKA-HDGPVFAMYALD--KGFVTGGKDGIVELWDDMFERCLKTYAIKR 879
           *98.*******99888..57*********************9997655 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

FSLALHPDKT LIATGQVGKE PYICIWDSYN VQTVSILKDV HTHGVACLAF DSDGQRLASV 60
GLDAKNTVCI WDWRKGKLLA SATGHSDRIF DISWDPYQPN RVVSCGVKHI KFWTLCGNAL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCAGCCTTG CCTTACACCC AGATAAAACT CTCATTGCAA CTGGCCAAGT TGGGAAGGAG 60
CCGTATATTT GCATATGGGA TTCCTATAAT GTCCAGACTG TGTCTATTCT CAAAGATGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001387	Ailuropoda melanoleuca	96.32	0.00e+00	3719.00
IUUC-Apl-003604	Anas platyrhynchos	92.80	0.00e+00	3578.00
IUUC-Aca-004572	Anolis carolinensis	88.64	0.00e+00	3477.00
IUUC-Ame-010713	Astyanax mexicanus	79.17	0.00e+00	3054.00
IUUC-Bta-012812	Bos taurus	96.11	0.00e+00	3711.00
IUUC-Cja-019191	Callithrix jacchus	95.90	0.00e+00	3713.00
IUUC-Cfa-020041	Canis familiaris	96.00	0.00e+00	3442.00
IUUC-Cpo-022304	Cavia porcellus	71.38	0.00e+00	2862.00
IUUC-Csa-023689	Chlorocebus sabaeus	95.66	0.00e+00	3706.00
IUUC-Cho-025038	Choloepus hoffmanni	94.52	0.00e+00	1476.00
IUUC-Cin-025205	Ciona intestinalis	60.59	0.00e+00	2419.00
IUUC-Csv-026014	Ciona savignyi	62.02	0.00e+00	2444.00
IUUC-Dre-028772	Danio rerio	72.82	0.00e+00	2944.00
IUUC-Dno-029982	Dasypus novemcinctus	94.86	0.00e+00	3659.00
IUUC-Dor-030980	Dipodomys ordii	68.14	0.00e+00	1283.00
IUUC-Ete-032554	Echinops telfairi	68.87	0.00e+00	816.00
IUUC-Eca-034161	Equus caballus	95.32	0.00e+00	3676.00
IUUC-Eeu-035180	Erinaceus europaeus	63.68	0.00e+00	1153.00
IUUC-Fca-036307	Felis catus	96.27	0.00e+00	3714.00
IUUC-Fal-037332	Ficedula albicollis	91.19	0.00e+00	3520.00
IUUC-Gmo-039057	Gadus morhua	73.21	0.00e+00	2818.00
IUUC-Gga-041095	Gallus gallus	73.62	0.00e+00	2095.00
IUUC-Gac-042555	Gasterosteus aculeatus	78.47	0.00e+00	3077.00
IUUC-Ggo-045107	Gorilla gorilla	96.11	0.00e+00	3717.00
IUUC-Hsa-046482	Homo sapiens	96.16	0.00e+00	3718.00
IUUC-Lch-050306	Latimeria chalumnae	72.72	0.00e+00	2751.00
IUUC-Loc-052642	Lepisosteus oculatus	86.86	0.00e+00	3358.00
IUUC-Laf-053649	Loxodonta africana	95.53	0.00e+00	3652.00
IUUC-Mcc-055361	Macaca mulatta	95.83	0.00e+00	3348.00
IUUC-Meu-056618	Macropus eugenii	75.71	0.00e+00	1675.00
IUUC-Mga-059202	Meleagris gallopavo	91.74	0.00e+00	3567.00
IUUC-Mmr-060729	Microcebus murinus	96.32	0.00e+00	3719.00
IUUC-Mdo-062462	Monodelphis domestica	94.06	0.00e+00	3653.00
IUUC-Mmu-063865	Mus musculus	95.32	0.00e+00	3690.00
IUUC-Mpu-066724	Mustela putorius furo	96.48	0.00e+00	3724.00
IUUC-Mlu-067816	Myotis lucifugus	96.27	0.00e+00	3729.00
IUUC-Nle-069911	Nomascus leucogenys	73.49	0.00e+00	2949.00
IUUC-Opr-070213	Ochotona princeps	95.03	0.00e+00	2006.00
IUUC-Ont-071928	Oreochromis niloticus	78.51	0.00e+00	3140.00
IUUC-Oan-073563	Ornithorhynchus anatinus	93.24	0.00e+00	3623.00
IUUC-Ocu-074531	Oryctolagus cuniculus	96.43	0.00e+00	3721.00
IUUC-Ola-086943	Oryzias latipes	77.34	0.00e+00	3101.00
IUUC-Olu-087860	Ostreococcus lucimarinus	38.84	4.00e-117	415.00
IUUC-Oga-088665	Otolemur garnettii	95.43	0.00e+00	3688.00
IUUC-Oar-090429	Ovis aries	96.27	0.00e+00	3718.00
IUUC-Ptr-091168	Pan troglodytes	86.75	0.00e+00	3290.00
IUUC-Pan-092788	Papio anubis	95.54	0.00e+00	3028.00
IUUC-Psi-093281	Pelodiscus sinensis	91.02	0.00e+00	3507.00
IUUC-Pma-094424	Petromyzon marinus	72.83	1.00e-124	438.00
IUUC-Pfo-096073	Poecilia formosa	73.62	0.00e+00	2978.00
IUUC-Pab-098561	Pongo abelii	94.93	0.00e+00	3204.00
IUUC-Pca-100177	Procavia capensis	83.63	0.00e+00	1514.00
IUUC-Pva-102880	Pteropus vampyrus	70.56	0.00e+00	2794.00
IUUC-Rno-105002	Rattus norvegicus	94.53	0.00e+00	3692.00
IUUC-Sha-107105	Sarcophilus harrisii	91.56	0.00e+00	3533.00
IUUC-Sar-113150	Sorex araneus	97.35	0.00e+00	765.00
IUUC-Ssc-116282	Sus scrofa	96.69	0.00e+00	3734.00
IUUC-Tgu-116807	Taeniopygia guttata	92.01	0.00e+00	3553.00
IUUC-Tru-118040	Takifugu rubripes	77.17	0.00e+00	3020.00
IUUC-Tsy-118941	Tarsius syrichta	64.94	0.00e+00	2245.00
IUUC-Tni-120118	Tetraodon nigroviridis	74.57	0.00e+00	2993.00
IUUC-Tbe-127467	Tupaia belangeri	68.69	0.00e+00	1460.00
IUUC-Ttr-129138	Tursiops truncatus	70.35	0.00e+00	2801.00
IUUC-Vpa-130083	Vicugna pacos	69.91	0.00e+00	2707.00
IUUC-Xtr-131835	Xenopus tropicalis	72.64	0.00e+00	2959.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence