iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066370

Ensembl Protein ID

ENSMPUP00000012114.1

UniProt Accession

M3YLA7; M3YLA7_MUSPF

Genbank Protein ID

ENSMPUP00000012114

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01033126

Gene Name

RNF149

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000012210.1	ENSMPUT00000012313.1	ENSMPUP00000012114.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.10e-06	29.0	268	309

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C e f  kd  ++lpC+H+fh+ C+  w         + +CP C+
   Q: 268  CAVCIENFkvKDVIRILPCKHIFHRICIDPW------LLDHRTCPMCK 309
           ********9988899****************......9999******6 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MACRRRPEAG VGARGALALL ALALNVPGAR GRALEWYSAV VSTEYVDPHT NRTVWSVSES 60
GRFGDSSPKE GAQGLVGVPR AADRDPEGCA PDTRFLVPAP GGQGDAPWVA LVARGGCTFK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGTGTC GGCGGCGACC CGAGGCTGGC GTCGGGGCCC GCGGCGCGCT GGCGCTGCTG 60
GCGCTGGCTC TGAACGTGCC CGGGGCCAGG GGCCGGGCGC TCGAGTGGTA CTCGGCCGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF02225--PA
PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0035690--P:cellular response to drug
GO:0043409--P:negative regulation of MAPK cascade
GO:0031647--P:regulation of protein stability

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001968	Ailuropoda melanoleuca	94.88	0.00e+00	699.00
IUUC-Apl-004109	Anas platyrhynchos	71.96	3.00e-98	351.00
IUUC-Ago-007863	Ashbya gossypii	37.21	1.00e-06	48.10
IUUC-Bta-012340	Bos taurus	84.02	9.00e-174	602.00
IUUC-Cja-019566	Callithrix jacchus	83.06	2.00e-174	604.00
IUUC-Cfa-020289	Canis familiaris	95.38	2.00e-125	441.00
IUUC-Cpo-021916	Cavia porcellus	66.67	3.00e-77	281.00
IUUC-Csa-024084	Chlorocebus sabaeus	84.38	1.00e-171	595.00
IUUC-Cho-024305	Choloepus hoffmanni	79.35	7.00e-130	456.00
IUUC-Cgl-026578	Colletotrichum gloeosporioides	48.08	3.00e-12	66.60
IUUC-Cne-026985	Cryptococcus neoformans	29.91	3.00e-11	64.30
IUUC-Dno-030098	Dasypus novemcinctus	82.96	2.00e-179	621.00
IUUC-Dor-030620	Dipodomys ordii	75.84	3.00e-145	508.00
IUUC-Ete-032306	Echinops telfairi	85.75	3.00e-173	600.00
IUUC-Fca-035950	Felis catus	89.84	5.00e-123	433.00
IUUC-Fal-037429	Ficedula albicollis	67.47	1.00e-134	472.00
IUUC-Fox-038011	Fusarium oxysporum	40.30	4.00e-13	69.70
IUUC-Fso-038141	Fusarium solani	43.04	5.00e-16	79.00
IUUC-Gga-041201	Gallus gallus	67.87	8.00e-132	463.00
IUUC-Ggo-045429	Gorilla gorilla	83.61	2.00e-166	578.00
IUUC-Hsa-046191	Homo sapiens	82.29	4.00e-175	607.00
IUUC-Itr-048018	Ictidomys tridecemlineatus	81.99	1.00e-157	548.00
IUUC-Lch-049498	Latimeria chalumnae	61.73	2.00e-132	465.00
IUUC-Laf-054239	Loxodonta africana	73.22	8.00e-129	453.00
IUUC-Meu-056382	Macropus eugenii	75.28	5.00e-152	530.00
IUUC-Mla-058935	Melampsora laricipopulina	39.02	2.00e-09	57.80
IUUC-Mmr-061513	Microcebus murinus	81.34	7.00e-172	596.00
IUUC-Mdo-063028	Monodelphis domestica	75.62	8.00e-155	539.00
IUUC-Mmu-063545	Mus musculus	79.36	8.00e-156	543.00
IUUC-Mlu-067271	Myotis lucifugus	81.16	8.00e-139	486.00
IUUC-Nle-069207	Nomascus leucogenys	84.22	6.00e-175	606.00
IUUC-Opr-070704	Ochotona princeps	72.87	9.00e-95	339.00
IUUC-Oan-072837	Ornithorhynchus anatinus	68.97	2.00e-143	501.00
IUUC-Ocu-074671	Oryctolagus cuniculus	79.72	8.00e-123	432.00
IUUC-Oga-089083	Otolemur garnettii	82.46	4.00e-174	603.00
IUUC-Oar-089254	Ovis aries	83.27	5.00e-115	406.00
IUUC-Ptr-090940	Pan troglodytes	84.05	1.00e-172	598.00
IUUC-Pan-092636	Papio anubis	84.11	5.00e-172	597.00
IUUC-Psi-093435	Pelodiscus sinensis	74.07	8.00e-92	329.00
IUUC-Pab-098525	Pongo abelii	84.49	8.00e-170	589.00
IUUC-Pva-102395	Pteropus vampyrus	83.96	8.00e-180	622.00
IUUC-Pgr-103263	Puccinia graminis	37.93	3.00e-12	67.40
IUUC-Rno-105789	Rattus norvegicus	79.45	1.00e-153	535.00
IUUC-Sha-107305	Sarcophilus harrisii	74.37	5.00e-95	340.00
IUUC-Ssc-115598	Sus scrofa	84.68	3.00e-174	604.00
IUUC-Tgu-116463	Taeniopygia guttata	66.39	3.00e-127	447.00
IUUC-Tsy-118915	Tarsius syrichta	79.67	7.00e-106	376.00
IUUC-Tre-121978	Trichoderma reesei	48.98	2.00e-12	67.40
IUUC-Tme-126970	Tuber melanosporum	49.06	1.00e-12	68.20
IUUC-Tbe-127906	Tupaia belangeri	67.35	5.00e-82	296.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence