iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000051956.4	ENSMUST00000063548.3	ENSMUSP00000066906.3
ENSMUSG00000051956.4	ENSMUST00000115354.1	ENSMUSP00000111011.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
TRANSFAC	RepTar
Post-translational Modifications (PTMs)
PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	9.10e-06	27.2	256	297

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC+e +   + +++l C+H+fh++C+  w         + +CP C+
   Q: 256  CVICFEAYkpNEIVRILTCKHFFHKNCIDPW------ILAHGTCPMCK 297
           ******9955334******************......99999*****6 PP

Organism

Mus musculus

Functional Description
(View)

Has E3 ubiquitin-protein ligase activity.

Protein Sequence
(Fasta)

MNPLQTSTWQ NQAPSFWLLR FSFIWLVSQK CCTASAVWTA YMNISFHVGN RMLSELGETG 60
VFGRSSILKR VAGVVVPPEG KIQNACDPNT TFILPRNKEP WIALIERGGC AFTQKIKVAS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGCAGTATC TAAAGTTACA GCAGTGAGAC AGGAATTTCT TTACTATCTA AAGCTTTTCT 60
CTCTAATAAA ACATCTGAAA CTCAAGACAT CTTTAGAAAG CTCTTGCTGA AACATGCTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0832--Ubl conjugation
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF02225--PA
PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0016740--F:transferase activity
GO:0008270--F:zinc ion binding
GO:0051865--P:protein autoubiquitination

KEGG

mmu:386611

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001468	Ailuropoda melanoleuca	79.94	1.00e-170	592.00
IUUC-Cpo-021838	Cavia porcellus	64.10	1.00e-143	502.00
IUUC-Csa-024064	Chlorocebus sabaeus	73.94	3.00e-169	587.00
IUUC-Cme-027309	Cyanidioschyzon merolae	38.46	7.00e-12	66.20
IUUC-Dno-029415	Dasypus novemcinctus	77.13	4.00e-175	607.00
IUUC-Dor-030278	Dipodomys ordii	71.09	3.00e-158	551.00
IUUC-Ete-033121	Echinops telfairi	68.07	5.00e-99	353.00
IUUC-Eca-033955	Equus caballus	76.06	2.00e-168	585.00
IUUC-Ggo-045319	Gorilla gorilla	73.40	3.00e-158	551.00
IUUC-Hsa-046802	Homo sapiens	73.94	1.00e-159	555.00
IUUC-Mlu-068071	Myotis lucifugus	72.87	2.00e-164	571.00
IUUC-Opr-070767	Ochotona princeps	76.60	9.00e-155	539.00
IUUC-Ocu-074834	Oryctolagus cuniculus	77.39	2.00e-180	624.00
IUUC-Oga-088182	Otolemur garnettii	76.86	2.00e-178	617.00
IUUC-Oar-089395	Ovis aries	75.86	3.00e-175	607.00
IUUC-Pva-103079	Pteropus vampyrus	73.61	8.00e-172	596.00
IUUC-Sha-106598	Sarcophilus harrisii	77.12	3.00e-169	587.00
IUUC-Tbe-127498	Tupaia belangeri	76.60	4.00e-177	613.00
IUUC-Ttr-129094	Tursiops truncatus	76.15	2.00e-172	598.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence