iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118441

UUCD1 version

UUC-TaR-00478

Ensembl Protein ID

ENSTRUP00000023176.1

UniProt Accession

H2TET3; H2TET3_TAKRU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000009215.1	ENSTRUT00000023272.1	ENSTRUP00000023175.1
ENSTRUG00000009215.1	ENSTRUT00000023273.1	ENSTRUP00000023176.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	58.38	3.00e-149	526.00	IUUC-Hsa-045805

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

LSHRGTMWSN LKSKCQTLFH NNSNPGPADS GPEADAVRCT LGGAAASGAS SPSRRLQPAP 60
AASAGRRHHN CVSNVPQIVE ITIDKESEDV RGDVGAVPLA RRDSYSRHAP WGGKKKHSCS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCTCCCACC GCGGAACCAT GTGGAGCAAC CTGAAGAGCA AATGCCAGAC GCTGTTCCAC 60
AACAACAGTA ACCCGGGACC TGCGGACAGC GGGCCGGAGG CGGATGCTGT CCGCTGCACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR022252--SOCS4/SOCS5_dom
IPR028420--SOCS5
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF12610--SOCS
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004860--F:protein kinase inhibitor activity
GO:0019221--P:cytokine-mediated signaling pathway
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0007259--P:JAK-STAT cascade
GO:0042059--P:negative regulation of epidermal growth factor receptor signaling pathway
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0006469--P:negative regulation of protein kinase activity
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000371	Aegilops tauschii	35.00	1.10e-01	29.60
IUUC-Aml-001789	Ailuropoda melanoleuca	44.87	7.00e-81	294.00
IUUC-Apl-003815	Anas platyrhynchos	60.41	4.00e-171	594.00
IUUC-Aca-004504	Anolis carolinensis	58.26	3.00e-159	555.00
IUUC-Ame-010677	Astyanax mexicanus	67.50	0.00e+00	648.00
IUUC-Bta-012338	Bos taurus	58.56	9.00e-167	580.00
IUUC-Bol-016597	Brassica oleracea	28.24	3.40e-02	33.50
IUUC-Cja-019828	Callithrix jacchus	58.38	1.00e-163	569.00
IUUC-Cfa-020369	Canis familiaris	58.75	9.00e-167	580.00
IUUC-Cpo-021397	Cavia porcellus	58.93	2.00e-168	585.00
IUUC-Csa-023856	Chlorocebus sabaeus	58.20	3.00e-166	578.00
IUUC-Cho-024700	Choloepus hoffmanni	42.89	2.00e-84	305.00
IUUC-Dre-028262	Danio rerio	67.50	6.00e-177	613.00
IUUC-Dno-029019	Dasypus novemcinctus	58.93	1.00e-169	589.00
IUUC-Dor-030273	Dipodomys ordii	43.90	1.00e-80	293.00
IUUC-Ete-032972	Echinops telfairi	45.91	2.00e-70	259.00
IUUC-Eca-033867	Equus caballus	58.55	1.00e-170	592.00
IUUC-Eeu-035208	Erinaceus europaeus	43.04	5.00e-80	291.00
IUUC-Fca-035806	Felis catus	58.41	5.00e-165	573.00
IUUC-Fal-037117	Ficedula albicollis	60.41	7.00e-171	593.00
IUUC-Gmo-039066	Gadus morhua	77.42	4.00e-95	341.00
IUUC-Gga-040876	Gallus gallus	60.04	2.00e-169	589.00
IUUC-Gac-042149	Gasterosteus aculeatus	79.01	0.00e+00	732.00
IUUC-Ggo-045169	Gorilla gorilla	57.27	2.00e-164	572.00
IUUC-Hsa-045805	Homo sapiens	58.20	3.00e-166	578.00
IUUC-Hvu-047122	Hordeum vulgare	41.38	1.60e+00	26.60
IUUC-Itr-049048	Ictidomys tridecemlineatus	58.93	9.00e-169	586.00
IUUC-Lch-049686	Latimeria chalumnae	59.82	6.00e-159	553.00
IUUC-Loc-051745	Lepisosteus oculatus	64.89	5.00e-170	590.00
IUUC-Laf-054124	Loxodonta africana	58.41	3.00e-169	588.00
IUUC-Mcc-055175	Macaca mulatta	58.20	3.00e-166	578.00
IUUC-Meu-056557	Macropus eugenii	60.92	3.00e-173	601.00
IUUC-Mga-059214	Meleagris gallopavo	60.41	3.00e-171	594.00
IUUC-Mmr-060613	Microcebus murinus	47.70	9.00e-114	403.00
IUUC-Mdo-062788	Monodelphis domestica	60.73	4.00e-169	587.00
IUUC-Mmu-064333	Mus musculus	60.26	3.00e-170	591.00
IUUC-Mpu-066048	Mustela putorius furo	58.38	4.00e-166	577.00
IUUC-Mlu-067430	Myotis lucifugus	57.46	6.00e-163	567.00
IUUC-Nle-069086	Nomascus leucogenys	58.75	3.00e-169	588.00
IUUC-Opr-070312	Ochotona princeps	59.30	3.00e-164	571.00
IUUC-Ont-072299	Oreochromis niloticus	78.04	0.00e+00	747.00
IUUC-Ocu-074123	Oryctolagus cuniculus	60.92	5.00e-163	567.00
IUUC-Ola-086934	Oryzias latipes	78.27	0.00e+00	756.00
IUUC-Oga-088535	Otolemur garnettii	58.96	8.00e-169	586.00
IUUC-Oar-089875	Ovis aries	58.61	4.00e-167	581.00
IUUC-Ptr-090541	Pan troglodytes	58.20	3.00e-166	578.00
IUUC-Pan-092416	Papio anubis	58.20	3.00e-166	578.00
IUUC-Psi-092960	Pelodiscus sinensis	59.12	2.00e-170	592.00
IUUC-Pma-094222	Petromyzon marinus	49.21	9.00e-96	344.00
IUUC-Pfo-096930	Poecilia formosa	74.20	0.00e+00	739.00
IUUC-Pab-098659	Pongo abelii	58.20	3.00e-166	578.00
IUUC-Pca-100222	Procavia capensis	58.38	5.00e-169	587.00
IUUC-Pva-102387	Pteropus vampyrus	58.01	4.00e-166	577.00
IUUC-Rno-105698	Rattus norvegicus	59.89	2.00e-169	588.00
IUUC-Sha-107234	Sarcophilus harrisii	60.00	5.00e-166	577.00
IUUC-Sar-113698	Sorex araneus	59.82	9.00e-155	540.00
IUUC-Ssc-115985	Sus scrofa	58.46	6.00e-169	587.00
IUUC-Tgu-116676	Taeniopygia guttata	60.41	6.00e-171	593.00
IUUC-Tsy-119163	Tarsius syrichta	56.23	1.00e-154	539.00
IUUC-Tni-120436	Tetraodon nigroviridis	83.24	0.00e+00	821.00
IUUC-Tae-124846	Triticum aestivum	35.00	2.00e-01	28.90
IUUC-Tbe-127353	Tupaia belangeri	58.56	7.00e-167	580.00
IUUC-Ttr-128907	Tursiops truncatus	58.38	5.00e-163	567.00
IUUC-Vpa-130140	Vicugna pacos	58.56	1.00e-166	579.00
IUUC-Xtr-132817	Xenopus tropicalis	57.70	9.00e-164	570.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence