iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-098510

Ensembl Protein ID

ENSPPYP00000011077.2

UniProt Accession

H2NYJ6; H2NYJ6_PONAB

Genbank Protein ID

ENSPPYP00000011077

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01252488

Gene Name

WDR62

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000009895.2	ENSPPYT00000011509.2	ENSPPYP00000011077.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-27	94.9	153	190
UBD/Beta-Prp	2.60e-56	191.1	495	753

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGs..dDgtikvWDlrtgv 34
           gH+ +v c+af ++ +++vs +  +D ++ vWD++++ 
   Q: 153  GHKYGVACVAFsPNmKHIVSMGyqHDMVLNVWDWKKDI 190
           89**********888*****9989*********98765 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk...ilvtgseDrtikvwdls.tgkcvhtlkghedsv 97
           ++++++spd+++la+g r+g +++++++ ++ l +++ h+aev ++++s+ +    +l+++s+Dr+i+v +++ ++   +tl  h++s+
   Q: 495  VRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETgltLLASASRDRLIHVLNVEkNYNLEQTLDDHSSSI 583
           67899*******************************************99887899***************997888999********* PP
   S: 98   lslsfspsg.dklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltgg 178
           ++++f  ++   ++s ++d+ i     ++g+   +        ++ +   + ++ ++++++ ++ Dr vr+++    k++k+ +  +g 
   Q: 584  TAIKFAGNRdIQMISCGADKSIYFRSAQQGSDGLHfvrtHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTvngKQKKCYKGSQG- 671
           *******885789********998666666655545332112222233446677778****************988888888888898. PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW.......dlrs 253
           +++s  ++ +d++g++l++   d+++ + d+ +gec+ ++ gh++ v+s++f+ + ++l+++s D  ++iW       ++ +
   Q: 672  DEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIVTSMKFTYDCHHLITVSGDSCVFIWhlgpeitNCMK 753
           999999999**************************************************************66554444433 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MAAVGSGGYA RNDAGEKLPS VMAGVPARRG QSSPPPAPPL CLRRRTRLST ASEETVQNRV 60
SLEKVLGITA QNSSGLTCDP GTGYVAYLAG CVVVILDPKE NKQQHIFNTA RKSLSALAFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAAGCGCCG GCTTTCCCGC GGCTGTTCGC TGTTCCAGTG GGTCGTGGCG GTGGCGGCAG 60
CGGCGGTTAG GGGATGTAAC GGTCGCCCGG CTGCGGCGTG ACGATGGCGG CCGTAGGGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR002469--Peptidase_S9B_N
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR030545--WDR62

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0005634--C:nucleus
GO:0000922--C:spindle pole
GO:0007099--P:centriole replication
GO:0021987--P:cerebral cortex development
GO:0007052--P:mitotic spindle organization
GO:0022008--P:neurogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001371	Ailuropoda melanoleuca	81.55	0.00e+00	2336.00
IUUC-Aca-004935	Anolis carolinensis	71.45	0.00e+00	1011.00
IUUC-Afu-008757	Aspergillus fumigatus	21.61	5.00e-29	123.00
IUUC-Bta-013336	Bos taurus	79.80	0.00e+00	2227.00
IUUC-Cel-018592	Caenorhabditis elegans	28.69	1.00e-74	275.00
IUUC-Cja-019094	Callithrix jacchus	88.98	0.00e+00	2554.00
IUUC-Cfa-020529	Canis familiaris	82.02	0.00e+00	2353.00
IUUC-Cpo-021970	Cavia porcellus	86.77	0.00e+00	1660.00
IUUC-Cre-022999	Chlamydomonas reinhardtii	28.38	8.00e-14	72.40
IUUC-Csa-024161	Chlorocebus sabaeus	93.41	0.00e+00	2687.00
IUUC-Cho-024310	Choloepus hoffmanni	84.80	0.00e+00	1169.00
IUUC-Cgl-026454	Colletotrichum gloeosporioides	22.71	3.00e-24	107.00
IUUC-Dre-028678	Danio rerio	57.13	0.00e+00	1006.00
IUUC-Dno-029933	Dasypus novemcinctus	75.10	0.00e+00	2086.00
IUUC-Dor-031147	Dipodomys ordii	76.99	0.00e+00	2098.00
IUUC-Dse-031501	Dothistroma septosporum	27.99	8.00e-24	106.00
IUUC-Eca-033675	Equus caballus	80.36	0.00e+00	2247.00
IUUC-Fca-035826	Felis catus	80.74	0.00e+00	2381.00
IUUC-Gma-043644	Glycine max	31.59	2.00e-101	363.00
IUUC-Ggo-045152	Gorilla gorilla	95.93	0.00e+00	2679.00
IUUC-Hsa-045891	Homo sapiens	95.73	0.00e+00	2694.00
IUUC-Itr-048019	Ictidomys tridecemlineatus	91.93	0.00e+00	1553.00
IUUC-Lch-049669	Latimeria chalumnae	48.59	0.00e+00	1062.00
IUUC-Loc-052488	Lepisosteus oculatus	56.13	0.00e+00	1027.00
IUUC-Laf-053992	Loxodonta africana	78.10	0.00e+00	2263.00
IUUC-Mcc-054994	Macaca mulatta	94.48	0.00e+00	2655.00
IUUC-Meu-056815	Macropus eugenii	78.91	0.00e+00	1420.00
IUUC-Mtr-058383	Medicago truncatula	30.21	1.00e-49	190.00
IUUC-Mmr-060693	Microcebus murinus	79.66	0.00e+00	2207.00
IUUC-Mdo-063007	Monodelphis domestica	62.76	0.00e+00	1765.00
IUUC-Mmu-064067	Mus musculus	74.89	0.00e+00	2111.00
IUUC-Mpu-066532	Mustela putorius furo	81.77	0.00e+00	2387.00
IUUC-Mlu-066982	Myotis lucifugus	77.62	0.00e+00	2106.00
IUUC-Nle-070042	Nomascus leucogenys	84.72	0.00e+00	2274.00
IUUC-Opr-070397	Ochotona princeps	79.49	0.00e+00	2277.00
IUUC-Ocu-074274	Oryctolagus cuniculus	79.47	0.00e+00	2188.00
IUUC-Oga-088577	Otolemur garnettii	81.73	0.00e+00	2320.00
IUUC-Oar-090117	Ovis aries	76.65	0.00e+00	2130.00
IUUC-Ptr-090553	Pan troglodytes	95.73	0.00e+00	2721.00
IUUC-Pan-092559	Papio anubis	91.12	0.00e+00	1441.00
IUUC-Psi-093710	Pelodiscus sinensis	64.05	0.00e+00	1382.00
IUUC-Pca-100323	Procavia capensis	71.99	0.00e+00	1340.00
IUUC-Pva-102895	Pteropus vampyrus	81.17	0.00e+00	2300.00
IUUC-Rno-105598	Rattus norvegicus	74.98	0.00e+00	2154.00
IUUC-Sha-107013	Sarcophilus harrisii	67.22	0.00e+00	1806.00
IUUC-Smo-109134	Selaginella moellendorffii	36.81	4.00e-133	469.00
IUUC-Sar-113261	Sorex araneus	75.43	0.00e+00	2072.00
IUUC-Ssc-115317	Sus scrofa	80.43	0.00e+00	2221.00
IUUC-Tsy-118799	Tarsius syrichta	91.90	0.00e+00	867.00
IUUC-Tme-127128	Tuber melanosporum	23.67	2.00e-32	135.00
IUUC-Tbe-127555	Tupaia belangeri	93.24	0.00e+00	1015.00
IUUC-Ttr-128722	Tursiops truncatus	79.56	0.00e+00	2239.00
IUUC-Vda-129957	Verticillium dahliae	22.61	7.00e-29	122.00
IUUC-Vpa-130392	Vicugna pacos	68.77	5.00e-108	385.00
IUUC-Xtr-131789	Xenopus tropicalis	59.88	0.00e+00	994.00
IUUC-Yli-134437	Yarrowia lipolytica	26.07	1.00e-16	82.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence