iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059720

UUCD1 version

UUC-MeG-00842

Ensembl Protein ID

ENSMGAP00000006279.2

UniProt Accession

G1N3I2; G1N3I2_MELGA

Protein Name

Uncharacterized protein

Gene Name

USP49

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000006273.2	ENSMGAT00000007026.2	ENSMGAP00000006279.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.90e-100	334.7	84	490

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle........kkkeklneenp....................................... 42
           tGl+NlgNtCYmNS+LQ+Ls+++++re++l+           +++    +                                       
   Q: 84   TGLRNLGNTCYMNSILQVLSHLQKFRECFLTldlceteeLLAKTV----Ngksrlpgrlangsaanesgrtdrvgsygaqslpaglngs 168
           7******************************88875554334444....2555599999999999999********************* PP
   S: 43   ...............kepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpke 116
                           +++ +l+++l++lf+ +w++k+  vsp ++l++++++ + f+gy+qqDaqEfl+ lld++++el         
   Q: 169  ssisrsleliqpkepRSKHISLCHELHTLFRVMWSGKWALVSPFAMLHSVWSLIPAFRGYDQQDAQEFLCELLDKVQQEL--------- 248
           ***99999999999999999************************************************************......... PP
   S: 117  eeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke..........slqdcLesft 195
           e+e+++++ l   +++k +k+  ++++++F+gql sq++c +c+ +s++ epf+dlsl++p++ ++ ++           l+++L++ft
   Q: 249  ESEGTKRRILIPFSQRKLTKQVLKVVNTIFHGQLLSQVTCITCNYKSNTVEPFWDLSLEFPERYHSIEKgiipvnqaecMLTEMLAKFT 337
           6788899999999**************************************************988666******************** PP
   S: 196  keeelegenkyycekckkkqe...........aekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqk 273
           ++e leg+  y c++c++k++           a+k+l++ +lP+vL lhLkRf++se+ ++reki  +v f + L+++p+c++++ ++ 
   Q: 338  ETEALEGRI-YACDQCNSKRRksspkplvlseAKKQLMIYRLPQVLRLHLKRFRWSER-NHREKIGVHVLFDQVLNMEPYCCRDSLSSL 424
           ******965.*******9999999*******************************997.8889********************887765 PP
   S: 274  e..kkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkrr 338
           +  +  Y+L+avv+H+G +++sGHY+ay++n++g+ W++++Dsk ++++ eev++   ++aY+lfY++r
   Q: 425  DkeTFVYDLSAVVMHHGkGFGSGHYTAYCYNTEGGfWVHCNDSKLNVCSVEEVCK---TQAYILFYTQR 490
           433899*************************9999********************...********985 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

ELEKKKEAAR RRRQEMKRQL LEELANTPPR KSARLLSHVH RENLIPRKFR EVATASPTSR 60
QMQSSRFNQF YSIRRKPLMT PGVTGLRNLG NTCYMNSILQ VLSHLQKFRE CFLTLDLCET 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGTTGGAGA AGAAGAAGGA GGCAGCTAGG CGGCGACGGC AGGAGATGAA GAGACAGCTT 60
CTGGAGGAGC TGGCAAACAC TCCTCCGAGG AAGAGTGCAA GGCTGCTGTC GCACGTGCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035616--P:histone H2B conserved C-terminal lysine deubiquitination
GO:0000398--P:mRNA splicing, via spliceosome
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002395	Ailuropoda melanoleuca	84.35	0.00e+00	751.00
IUUC-Apl-003658	Anas platyrhynchos	97.86	0.00e+00	1014.00
IUUC-Aca-005278	Anolis carolinensis	90.96	0.00e+00	950.00
IUUC-Cho-025051	Choloepus hoffmanni	80.68	4.00e-168	584.00
IUUC-Dre-027577	Danio rerio	66.33	8.00e-172	596.00
IUUC-Fca-035919	Felis catus	85.00	0.00e+00	706.00
IUUC-Fal-037290	Ficedula albicollis	90.14	0.00e+00	878.00
IUUC-Gmo-039249	Gadus morhua	79.56	2.00e-152	532.00
IUUC-Gga-040383	Gallus gallus	96.17	0.00e+00	953.00
IUUC-Loc-051961	Lepisosteus oculatus	74.49	0.00e+00	701.00
IUUC-Laf-053819	Loxodonta africana	84.15	0.00e+00	751.00
IUUC-Mdo-062073	Monodelphis domestica	89.62	0.00e+00	946.00
IUUC-Mpu-066318	Mustela putorius furo	85.32	0.00e+00	777.00
IUUC-Oan-073245	Ornithorhynchus anatinus	89.68	0.00e+00	633.00
IUUC-Ola-086413	Oryzias latipes	68.55	0.00e+00	662.00
IUUC-Oar-089462	Ovis aries	81.32	0.00e+00	726.00
IUUC-Psi-093353	Pelodiscus sinensis	94.15	0.00e+00	976.00
IUUC-Pma-094155	Petromyzon marinus	56.90	9.00e-84	302.00
IUUC-Sha-107337	Sarcophilus harrisii	89.35	0.00e+00	919.00
IUUC-Sar-113561	Sorex araneus	87.95	5.00e-86	310.00
IUUC-Tgu-117025	Taeniopygia guttata	83.40	0.00e+00	794.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence